Angiolymphoid hyperplasia with eosinophilia

Angiolymphoid hyperplasia with eosinophilia is a rare condition and is poorly recognized in the otolaryngological literature. The condition is characterized by the appearance of cutaneous nodules within the head and neck region especially around the external ear. Variable lymphadenopathy and peripheral eosinophilia can occur and the condition can mimic neoplasia. It is important to be aware of this disease entity in order to avoid overtreatment. Surgical removal is the treatment of choice; however, this often multilobulated and poorly delineated lesion often precludes initial wide excision and local recurrence is common. We present three cases of this unusual condition and a brief resumé of the literature.     

Angiolymphoid hyperplasia with eosinophilia (Kimura's disease). Apropos a case report with ultrastructural and histoenzymological study

One case of angiolymphoid hyperplasia with eosinophilia is related in a 30-years old woman. This observations has all the characteristics of the disease: telangiectasic oedema, nodules and infiltrated areas located in the cervico-facial skin and also in the nasal and buccopharyngeal mucosa. Histologically, the proliferation is made of adult or young capillaries surrounded by inflammatory cells. The results of the peculiar morphological methods used here prove the endothelial nature of cells: high enzymatic activities of alkaline phosphatase and ATPases; factor VIII present on the cells; ultrastructural features characteristic of more or less differentiated vessels. Besides their nosologic interest, these methods may be useful for the diagnosis of this disease with the other vascular tumors.     

Angiolymphoid hyperplasia with eosinophilia — A case report

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a distinctive vascular tumor presenting as isolated or grouped papules or plaques or nodules over skin in head and neck. We, hereby, present a case of ALHE affecting the base of tongue-a rare site of involvement.     

Angiolymphoid hyperplasia with eosinophilia: a case report and literature review

Angiolymphoid hyperplasia with eosinophilia is a rare, benign vascular tumor affecting principally the head and neck region of young adult females. Microscopic analysis reveals hyperplastic blood vessels lined by a hypertrophic endothelium. An inflammatory infiltrate rich in eosinophils is also present. Etiology of the lesion is unknown. Various treatment modalities have been described. We describe a case successfully treated by extensive excision and reconstruction.     

Angiolymphoid hyperplasia with eosinophilia of the auricle: progression of histopathological changes

Angiolymphoid hyperplasia with eosinophilia is a rare condition that demonstrates dermal or subcutaneous proliferation of endothelial cells associated with an inflammatory cell infiltrate. A case is reported, with emphasis on the histopathological features on repeated biopsies. The report serves to stress the importance of considering this condition in the differential diagnosis of lesions in and around the ear.     

Angiolymphoid hyperplasia with eosinophilia. A case report and review of the literature

A patient had skin and subcutaneous manifestations of angiolymphoid hyperplasia with eosinophilia. The diagnosis and treatment of this angioproliferative disease with a predilection for the head and neck were determined, and recommendations were made for avoiding surgical misadventure.     

Angiolymphoid hyperplasia with eosinophilia: an uncommon tumor of the external auditory canal

We present a case of an 80-year-old woman with a six-month history of painless nodules in her external auditory canal. Biopsies of these nodules revealed ALHE. This type of lesion rarely has been reported in the otolaryngologic literature, despite the fact that the head and neck are sites of predilection. The potential of malignancy with this disorder is debatable, and the histologic features overlap with other benign and malignant vascular tumors. Thus, adequate local excision is recommended.     

Angiolymphoid hyperplasia with eosbvophilia-case report

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign condition characterized by subcutaneous lesions in the head-neck region. It is frequently misdiagnosed as a malignant lesion. Knowledge of the existence of the disease and pathological interpretation are requisites for early diagnosis. We present a case report and review of the literature.     

Angiolymphoid hyperplasia of the head and neck

Angiolymphoid hyperplasia is a rare benign condition affecting the skin and subcutaneous tissue of the head and neck. Superficial (intradermal) lesions frequently affect the external ear and such a case presenting to an otolaryngologist is described. Clinically the disease is characterized by single or multiple plum-coloured nodules or plaques which are often itchy and may bleed with mild trauma. Histologically the lesions are composed of proliferating capillary vessels associated with a heavy inflammatory infiltrate including eosinophils and mast cells. The cause remains obscure. The lesions often persist for many years and may regress spontaneously. Several forms of treatment have been used, including cryosurgery, curettage and diathermy, radiotherapy and intralesional steroid injections. In this case the Argon laser was employed.     

Kimura's disease: a case report

Kimura's disease is a rare, idiopathic condition that usually affects young men of Asian descent. The decrease is characterized by swelling and lesions in the head and neck region, with involvement of the subcutaneous soft tissue, major salivary glands, and lymph nodes. Patients almost always have eosinophilia and elevated serum immunoglobulin E levels. The diagnosis is established by biopsy. Kimura's disease is usually self-limiting. Its etiology is unknown but is thought to be a manifestation of an aberrant allergic response. In this paper, we describe the case of a 30-year-old patient who was diagnosed with Kimura's disease at our institution.     

Kimura's disease of the parapharyngeal space

Kimura's disease is a fairly uncommon inflammatory condition of unknown etiology. It classically presents in young Asian males as tumorlike subcutaneous nodules in the head and neck with associated lymphadenopathy, peripheral eosinophilia, and an elevated serum IgE level. Kimura's disease affects the subcutaneous tissues, salivary glands, and lymph nodes; less common sites in the head and neck include the eyelid and tympanic membrane. We report a case of Kimura's disease of the parapharyngeal space in a 42-year-old Chinese woman. To the best of our knowledge, this is the first report of Kimura's disease at this site.