共查询到16条相似文献,搜索用时 109 毫秒
1.
婴儿腭部郎格汉斯细胞组织细胞增生症(Langerhans cell histiocytosis,LCH)在临床上较少见。本文报告1例婴儿腭部LCH病例,结合文献复习,从发病率、临床表现、影像学特点、诊断、临床分型、分级、治疗方法和预后等方面进行讨论。本例患者采用局部肿块刮除加术后化疗,效果良好。 相似文献
2.
3.
本文报道1例下颌骨朗格汉斯细胞组织细胞增生症。患者,女性,34岁,左下后牙龈疼痛1年,伴溢脓2个月,经组织病理及免疫组织化学检查证实为朗格汉斯细胞组织细胞增生症。 相似文献
4.
颌骨郎格罕细胞组织细胞增生症的临床病理及免疫组化研究 总被引:3,自引:0,他引:3
目的研究慢性局限性郎格罕细胞组织细胞增生症(Langerhanscelhistiocytosis,LCH)的组织病理学及免疫组织化学特点。方法HE染色及组织学观察,有丝分裂计数和免疫组织化学染色。结果本项研究包括22例LCH。HE染色见郎格罕细胞(LC)核因扭曲而呈现多样性,核分裂并不少见(平均每10个高倍视野7.1个核分裂像)。片状排列的细胞间可见明显不规则的细胞间隙。免疫染色见LCS-100阳性,增殖细胞核抗原(PCNA)阳性率平均为14.5%,病变中还散在CD68及组织蛋白酶D阳性的组织细胞,淋巴细胞以T细胞为主。结论上述结果提示,LC细胞核形态的多样性及细胞排列是诊断本病的基础;该病变的性质是LC增殖而不是LC单纯聚积,可能属于肿瘤性增生;病变中的LC属不成熟的LC前体细胞。 相似文献
5.
<正>恶性组织细胞增生症(malignant histiocytosis,MH)是全身性进行性单核吞噬系统的组织细胞及其前身细胞弥漫性浸润的恶性疾病,是系统性、进行性、浸润性非典型组织细胞增生的恶性肿瘤。小儿较少见,占小儿恶性肿瘤的10.4%[1],病死率极高,多在发病半年内死亡[2]。因其临床表现复杂多样,缺乏特异性,实验室检查结果亦可阴性,病程进展迅速,自然病程短,故确诊较困难。当合并颌面感染 相似文献
6.
吕炳辉 《口腔颌面外科杂志》2003,13(4):294-294
朗格汉斯组织细胞增生症又称组织细胞增生症X或网状内皮细胞增生症,可以单发或多发,包括3个类型。此病较少见,现将我科的l例报道如下。 患者,女,5岁。因右愕部肿物1年余,于2(X)2年7月22日人院。患者1年前发现右愕部有肿物隆起,渐进性增大,伴轻度疼痛,无发热,无其他不适。未曾做过任何治疗。检查见右愕部粉红色隆起增生物,边界不清,波及对侧愕部,质地中等偏硬,无活动,有轻度压痛,头颈浅表淋巴结未触及。人院后,先行抗炎治疗,效果不佳。2以犯年7月26日行愕部肿物活检术。术中见右侧牙槽晴骨质破坏,恒牙胚松动。病理:可见粘膜组织被覆鳞状上皮… 相似文献
7.
8.
郎格罕细胞组织细胞增生症(Langerhans cell histiocytosis,LCH)是一组病因不明、以病理性郎格罕细胞增生、浸润为主要特点的疾病,临床上成人LCH较少见,亦少累及上颌骨和腭部。本文报道了一例以腭部溃疡为主诉的成年LCH病例,并通过对近年相关文献的复习,介绍LCH的病因、临床损害特点、诊断标准、分类、治疗等。 相似文献
9.
本文对原发于下颌骨的21例(26个病灶)组织细胞增多症的X线表现进行了讨论。通过对病灶所在下颌骨不同区域的划分和分析X线片上各病灶对骨的破坏方式和牙体、牙囊的影响及其与邻近正常骨质结构的关系,作者们提出了自己对本病X线特征性表现的看法和有关的鉴别诊断问题,以期加深对本病X线表现的认识。 相似文献
10.
32例小儿边缘性下颌骨骨髓炎临床分析安徽省阜阳地区人民医院口腔科丁杉,杨玲安徽省阜阳地区人民医院儿科陈梦琪我院1977年~1992年共收治小儿边缘住下颌骨骨髓炎32例,分析如下。临床资料一般资料:我院近15年间共收治下颌骨骨髓炎266例,其中小儿边缘... 相似文献
11.
Eleven cases of Langerhans' cell histocytosis of the jaw bones are reported. The clinial and radiographical features are described, and the role of the dentist in the diagnosis and management of this disorder is discussed. 相似文献
12.
Takashi Kaneda D.D.S. Ph.D. Manabu Minami M.D. Mitsuaki Yamashiro D.D.S. Yoshiaki Akimoto D.D.S. Ph.D. Hiroyuki Okada D.D.S. Ph.D. Hirotsugu Yamamoto D.D.S. Ph.D. Hiromi Suzuki D.D.S. Ph.D. Yasuhito Sasaki M.D. Ph.D. 《Oral Radiology》1997,13(2):109-114
Langerhans cell histiocytosis in the mandible is a rare disease. The clinical and advanced imaging features of Langerhans
cell histiocytosis in an 18-year-old male are presented. CT images showed an diffuse, ill-defined, expansile lesion of heterogeneous
density extending from the anterior mandibular area to the right molar area. CT was particularly helpful in confirming a cortical
invasion. T1-weighted gradient echo MR images revealed a heterogeneously low-to high-signal intensity lesion in the right
side of the mandible. T2-weighted spin echo MR images showed a heterogeneously iso-to high-signal intensity area with low-intensity
areas. Multidirectional MR images revealed the extent of the lesion in the mandibular bone marrow more clearly than CT. 相似文献
13.
Eleven cases of Langerhans' cell histocytosis of the jaw bones are reported. The clinial and radiographical features are described, and the role of the dentist in the diagnosis and management of this disorder is discussed. 相似文献
14.
Andrew M. Felstead Barry G. Main Steven J. Thomas Ceri W. Hughes 《The British journal of oral & maxillofacial surgery》2013
We report a case of Langerhans cell histiocytosis with a restricted presentation (eosinophilic granuloma of the mandible) complicated by multiple reactivations. 相似文献
15.
Langerhans' cell histiocytosis (LCH) is a rare disease where different organs and systems may be affected. Oral involvement generally consists of mucosal ulceration associated with lesions of the underlying bone. Many reports exist about the misdiagnosis of this disease. Various symptoms may lead the clinician to an incorrect diagnosis, especially with multiple organ involvement. Oral manifestations are common, and dentists should be aware of this disease and evaluate intraoral findings accordingly. This study presents an LCH case characterized by oral mucosal ulcerations with no involvement of the underlying bone. A definitive diagnosis was made by open biopsy from the oral mucosa. 相似文献
16.
J. G. C. Saunders J. W. Eveson M. Addy C. N. Bell 《Journal of clinical periodontology》1998,25(4):340-342
Abstract. Eosinophilic granuloma represents one of a triad of lesions encompassing a disease under the generic name, histiocytosis X or Langerhans cell histiocytosis. Localised eosinophilic granuloma, muitifocal eosinophilic granuloma, Hand-Schüller-Christian disease, and the most malignant form of histiocytosis, Letterer-Siwe disease, can all present as destructive bony lesions of the jaws. The present case was a 30-year-old man who presented with almost total destruction of the periodontal support to the left and right mandibular, 1st and 2nd molars. Whereas the radiographic features were typical of eosinophilic granuloma, the clinical appearance and mirror image presentation were unusual. 相似文献