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ENDEMIC CHRONIC ARSENISM IN XINJIANG 总被引:1,自引:0,他引:1
Huang Yue-zhen黄月珍 Qian Xu-chun 钱戌春 Wang Guo-quan 王国荃 Xiao Bi-yu 肖碧玉 Ren Dun-ding任敦鼎 Feng Zhao-yue冯兆悦。 Wu Ji-yao吴继尧 Xu Rong-jiang徐荣江and Zhang Feng-e张风娥 《中华医学杂志(英文版)》1985,98(3):219-222
This paper reports an investigation of endemic
chronic arsenism due to drinking deep artesian well
water in a plant in Kuitun Area, Xinjiang Uighur
Autonomous Region. The 0.6 mg L arsenic concen
tration of this water was 15 times the maximal per'
missible concentration. In the plant, endemic chronic
arsenism morbidity rate was 44.6To. The clinical
features and histopathologic changes of this disease
are described. The authors believe that areas of
hyperpigmentation mixed with whitish depigmented
spots are typical arsenic dyspigmentation, and that
the spotted keratosis and corn-like keratosis palmaris
et plantaris are typical arsenic keratosis although
there are no standardly recognized specific diagnostic
pathologic changes. These characteristic changes
may aid in diagnosis. 相似文献
3.
Liu Yan-fang刘彦仿 Hu Ming-qin胡明钦 Departme''nt of Patholog''y th Militar''g Medical College Niu Shu-miao牛恕淼 Department of Pathology Xian Medical Col.lege Xian Wu Yan-ling吴延玲Department of Patlzology Shaanxi Medical Coll ege for Advanced Stud''y Xia}z 《中华医学杂志(英文版)》1984,97(6):429-432
ChroLnic lymphocytic thyroiditis and lympho-
cyte infiltration were studied in 2,053 cases of
endemic goiter. Only 7 cases of chronic lympho-
cytic thyroiditis and 3 0f focal thyroiditis
showed diffused enlargement of thyroid. Among
2,053 cases, 150 had thyroiditis (7.3%), of whom
137 (7.1%) were accompanied by nodular goiters.
If focal thyroiditis was excludetl, the incidence
rate of chronic lymphocytic thyroiditis would be
2.39T%
The increased incidence of Hashimoto's
disease was considered to he due to the decreased
incidence of endemic goiter and the neglect of
chronic lymphocytic thyroiditis accompanied by
nodular goiters. Thyroiditis occurs in the sur-
rounding tissues of the nodule, and it is why
the changes in thyroiditis were overlooked iii
excised nodules. 相似文献
4.
Zhu Xianyi 《中华医学杂志(英文版)》1981,94(9):555-566
This paper report,s the iodine metabolism
and pituitary-thyroid axis function among the
inhabitants of an untreated endemic goiter
region in the southeast.ern part (Heba commune)
of Guizhou province.
The results of the investigation showed
that the urine iodine excretion of the inhabi-
tants in the untreated endemic goiter region was
lower than that of those in the normal non-
endemic region, a rural commune of Guiyang
city and an iodized salt treated endemic region,
Shilong commune. The urine iodine excretion
was low not only among the goiter patients and
cretins but also among the nongoitrous adults
and children. Same was with the 24 hr thyroid
.131I uptake figures which were higher than
normal among the goiter patients and cretins as
well as nongoitrous adults and children in Heba
commune. It is concluded that in the endemic
goiter region, the goiter patients and cretins as
well as the nongoitrous adults and children are
suffering from iodine deficiency.
Studies of pituitary thyroid axis function of
the inhabitants in the untreated endemic goiter
region, Heba commune, showed basically normal
values for serum T3, definitely low values for
serum T4 and markedly elevated values for se-
rum TSH. The relation_ship between low serum
T4 and elevated serum TSH was frequently ob-
served among the cretins and the goiter ;patients
although myxedema was rarely manifested.
Thus hormonal hypothyroidism was not un-
common among the inhabitants of Heba com-
mune and the term "euthyroidism" should be
used with discretion. 相似文献
5.
目的 了解淄博市的地方性氟中毒现状,为病情预测和开展水氟的健康干预提供技术依据。方法 收集2008—2012年间淄博市农村饮水工程末梢水氟化物监测数据,对比2012年地方性氟中毒的分布情况,应用地理信息系统(GIS)技术分析水氟浓度和地方性氟中毒之间的可能关联。结果 淄博市水氟呈现明显的地区聚集性,水氟浓度的空间分布预测显示,高青县和桓台县为高氟区,以高高相邻为主,与淄博市2012年的氟中毒病区分布存在对应关系。结论 淄博市地方性氟中毒以高青县最为严重,为以后重点防控区域;GIS分析对病情预测和健康干预具有科学指导意义。 相似文献
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In treating endemic goiter, we have
discovered that oral administration of
iodine requires prolonged therapy, incurs
high expenditures and is ineffective in
larger or nodular goiters and surgical treat-
ment requires a certain amount of equip-
ment and technical facilities, which is in-
convenient for large scale adoption. One
day in 1970, poor peasant Grandma Liu
Teh-shan came to our scientific research
group, asking for a goiter operation. After
a careful examination, her age and poor
health left us with no choice and we hacl
to refuse her request. Grandma LiLi uncler-
stood us and saicl: "Couldn't you try to
think of a method to cure me without an
operation?” This typical hope of the poor
and lower middle peasants of the area
spurred us into seeking a nexv non-opera-
tive method for them. 相似文献
8.
辽宁省地方性氟中毒流行病学调查 总被引:1,自引:0,他引:1
我们从1980到1983年对辽宁省进行了地方性氟中毒流行病学调查。辽宁省有饮水型和燃煤污染型两类地方性氟中毒病区。饮水氟含量在1.1~17.0mg/L之间的高氟区,有人口837 795人,氟中毒病人数395 880人,分布于40个县区,2428个村。重病区在辽东和辽西山地间的辽河平原(新民、法库、彰武和康平)地区、辽西的北部(建平、北票和阜新)地区以及温泉区。干旱气候区浅层潜水型病区分布在中长铁路以西地区,深层地下水型病区在锦县、盘山等渤海湾沿岸区。全省48个温泉中有34个是病区。燃煤污染型病区分布在本溪县。 相似文献
9.
地方性克汀病患者红细胞SOD和LPO的测定 总被引:2,自引:0,他引:2
作者测定了严重碘缺乏地区神经型克汀病患者的红细胞中的SOD活性及LPO含量。结果发现患者比正常人血中红细胞SOD活性显著降低,LPO含量明显升高,SOD/LPO比值下降。上述结果表明地方性克汀病的发病可能与自由基损伤作用有关。 相似文献
10.
任大礼 《山东医学高等专科学校学报》1989,(4)
定群观察了食盐加碘对地方性克汀病流行的影响。在我县低碘的三岔、土门两乡30个村38321人中,分别用食盐加碘和不加碘进行了10年定群研究观察,结果对照组与食盐加碘组人年发病率出现显著性差异(p<0.05),RR=5.89,AR%:83%。此后,两组皆食盐加碘观察6年,对照组人年发病率降至0.91/10万,两组的地方性克汀病流行均基本控制。 相似文献
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Zhu Xian-yi 朱宪彝 I。u Ti-zhang 卢倜章 Song Xi-kun 宋喜坤Li Xi-tian 李锡田 Gao Shi-mei 呙士美 Yang He-mei杨鹤梅Ma Tai 马太 Li Yun-zhi 李云志 Zhang Wan-quan张万权 《中华医学杂志(英文版)》1984,97(7):545-550
The incidence of goiter in two villages of Shi-
jiu Commune situated along the sea coast was 31.3
and 41.7To, and the average urine iodine excretion
was l,423.0 and 2,097.0 Ug/g creatinine, respectively.
Their average iodine contents in drinking water
were 35.5 and 26.0 vg/L, respectively. Because the
inhabitants in the villages consumed large quantities
ot' kelp salt and its pickled vegetables, we believed
that goiter was caused by excessive intake of iodine.
The other two villages in Taole Commune had simi-
tar geographical conditions as Shijiu Commune did,
but their inhabitants took iodine deficient common
table salt. Their goiter incidence was 6.7To and
8.Oc70, respectively. Goiter in these villages is consider-
ed as mild iodine excess goiter. The goiter incidence
in Mazhao Commune of a hilly region 15 kilometers
away from the sea, and in Huangdun Commune of
a mountainous region 30 kilometers away from the
sea, was 29.4'70 and 23.5'70, respectively. The average
urine iodine excretion was low (46.5 and 23.96 u.g./g
creatinine); it was associated with the low iodine
content of drinking water (1.5 and 0.65 ug/L). The
inhabitants in both regions were all peasants consum
ing iodine deficient table salt. Therefore, goiter in
the latter two communes is considered as the com
mon iodine deficient goiter. 相似文献
13.
《中华医学杂志(英文版)》1982,95(1):7-14
An epidemiologic investigation on endemic
goiter and cretinism in southeastern Guizhou
province was carried out in 1979. The incidence
of goiter in Shilong, Heba and Pingliang com-
munes was 23.2%, 31.5%。
Qianling commune was
and 30.4% respectively.
taken as a nonendemic
control with a goiter rate of 0.97%. The in-
cidence of endemic cretinism was 5.2%, 3.1% and
2.8% for Shilong, Heba and Pingliang communes
respectively. No endemic cretinism was dis-
covered in Qianling commune. Female goiter 相似文献
14.
对湖南省涟源市不同地方性氟中毒发病区的二个自然村的全体人群进行氟斑牙普查,部分人群进行骨X线、尿氟和发氟检查、并同时测定两村的空气、土壤、水和食物中的氟含量。结果提示,氟中毒高发区的唐家村属显著流行区,其主要氟源是土壤。 相似文献
15.
Z F Shi G H Zeng J X Zhang X T Li M T Hou T Z Lu J B Wu G X Wang Z Z Tian J L Liu 《中华医学杂志(英文版)》1984,97(9):689-697
This paper reports morbidity of endemic cretirr
ism in endemic areas of 3 agricuftural communes in
southeastern and southern Guizhou. They were 3.1'io,
2.8'70 and 5.2To in 1979. Retardation of physical deve-
lopment before 7 years of age is seen. Thyroid
gland biopsy shows hyperplasia; point patches
are scattered in scans and l/.scintiscans and there
are cold and warm nodules. The surface area of
thyroid gland is either normal, decreased or increased.
There is mental retardation in all patients. The deaf
mutism or cerebral palsy is a characteristic of neural
deficit. The roentgenographic features are delayed
bony age and late ossification center of the
femoral head. In this group iodine uptake of thyroid
gland is increased apparently, urine iodine 25yg'gm
cretinine, serum T4 4.1Vg/dl, TSH 36.3yU;ml. This
group shows both severe psychoneurologic defects
and evident hypothyroidism without myxedema, and
is classified as the so-called mixecl type of cretinism. 相似文献
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S Luo F S Ye Z C Mo Y X Su J S He C Q Zhou M J Tong B E Henderson M C Yu 《中华医学杂志(英文版)》1988,101(9):654-658
Fifty patients with primary hepatocellular carcinoma (PHC) and 49 controls were assayed for he-
patitis B virus (HBV) markers by radioimmunoas.
say. The results showed that the hepatitis B surface
antigen (HBsAg) was positive in 43 0ut of 50 (8670)
PHC patients and in 11 0ut of 49 (22.570) controls
(p<0.001). Both anti-HBs and anti-HBc were present
in six PHC patients and in 27 controls. The positive
rate for at least one HBV marker was 9870, (49/50) in
the PHC patients. The rellationship between HBsAg
positivity and PHC in our young patients suggests
that these individuals were infected by the HBV in
their early life either by vertical transmission from
the carrier mothers during the perinatal period or by
close family contacts during the postnatal period.
This study confirmed the strong geographic correla-
tion between HBsAg prevalence and incidence of
PHC. 相似文献
19.
于志恒 《河北医科大学学报》1988,(2)
高碘地方性甲状腺肿是新认识的一种地方病。1978~1981年,在河北省渤海湾海滨进行了一系列调查,通过流行病观察和动物实验证实,此地的地方性甲状腺肿是由于高碘水所引起。现在,不仅河北、山东省的沿河地区,就是内陆地区的山西省与新疆自治区亦发现此病。 相似文献