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目的 观察联合应用不同根管充填糊剂治疗慢性根尖周炎的临床疗效.方法 选取2007-2009年山东大学口腔医学院综合科门诊诊治的慢性根尖周炎患者298例(422颗牙),按患者就诊先后顺序随机分为4组.A组(AH Plus糊剂+Vitapex糊剂+牙胶尖)75例患者108颗牙,B组(AH Plus糊剂+牙胶尖)75例患者105颗牙,C组(Vitapex糊剂+牙胶尖)74例患者105颗牙,D组[氧化锌丁香油糊剂(ZOE)糊剂+牙胶尖]74例患者104颗牙.对4组术后7 d、6个月、1年的临床疗效进行比较、分析.结果 298例患者根管充填7 d后复查,A、C组术后反应轻,与B组比较,差异具有统计学差异(P＜0.05);D组术后反应最重,与其他3组比较,差异均有统计学意义(均P＜0.05).根管充填6个月、1年后复查的结果没有差异(P＞0.05),A组有效率最高,与其他3组比较,差异有统计学意义(P＜0.05);D组有效率最低,与其他3组比较,差异有统计学意义(P＜0.05).结论 AH Plus糊剂+Vitapex糊剂+牙胶尖治疗慢性根尖周炎,既诱导了根尖周阴影区的骨质增生修复,又能使根尖孔形成完善的封闭,达到治愈根尖周炎、防止继发感染或复发的目的 .     

Vitapex糊剂治疗具有明显根尖手术指征的根尖周炎疗效观察

目的　探讨用Vitapex糊剂治疗具有明显根尖手术指征的根尖周炎临床治疗效果。方法　对患根尖周炎具有明显根尖手术指征的 12 0颗牙 ,预备根管后用Vitapex糊剂加牙胶尖根管充填治疗。结果　经过 18个月到 4年的临床随访 ,113颗牙成功保留 ,成功率 94 .2 %。 5 6例有瘘管者瘘管全部消失 ;85例根尖阴影全部消失 ;2 8例根尖阴影明显缩小 ;32例病例治疗后当天患牙有浮出伸长感 ,咀嚼痛 ,2～ 3d后自行缓解。结论　Vitapex糊剂是一种适合治疗具有明显根尖手术指征的根尖周炎的根充材料     

不同材料根管充填后近期疼痛发生情况分析

目的比较活髓牙经不同材料根管充填后的疼痛发生情况。方法288颗需要进行根管治疗的活髓牙分为4组,2组分别采用Cortisomol糊剂+牙胶尖和Vitapex糊剂+牙胶尖一次性根管充填;2组经引流24～48h后,分别用Cortisomol糊剂+牙胶尖和Vitapex+牙胶尖根管充填;观察术后1周内的疼痛发生情况。结果所有患牙中,根充后可自愈性疼痛的发生率为22.6%,非自愈性疼痛的发生率为2.08%;一次性根充组中,Cortisomol糊剂组较Vitapex糊剂组的可自愈性疼痛发生率低,有显著性差异(P<0.01);引流后根充组中,Cortisomol糊剂组较Vitapex糊剂组的可自愈性疼痛发生率低,但无显著性差异(P>0.05);各组间非自愈性疼痛的发生率均无显著性差异(P>0.05);大多数患牙根充后的疼痛发生在72h之内。结论Cortisomol糊剂+牙胶尖根管充填可以减少根充后疼痛的发生。     

3种糊剂根充效果观察

目的 观察CRCS氢氧化钙糊剂、AH-plus糊剂、Cortisomol糊剂在根管充填术后1周的急性反应及1年的临床效果。方法 慢性根尖周病患牙360颗随机分成三组,其中CRCS氢氧化钙糊剂组119颗,AH-plus糊剂组117颗,Cortisomol糊剂组124颗。分别采用糊剂加牙胶尖根管充填,观察术后1周及1年的疗效。结果 CRCS氢氧化钙糊剂根充后1周无疼痛发生率为87.4%,根充后1年的总有效率为92.4%;AH-plus糊剂根充后1周无疼痛发生率为87.2%,根充后1年的总有效率为92.3%;Cortisomol糊剂根充后1周无疼痛发生率为84.7%,根充后1年的总有效率为91.1%;无统计学意义。结论 三种根充糊剂均为目前较理想的根充糊剂。     

不同根充糊剂根尖封闭性的比较研究

目的　比较不同根充糊剂根管充填后的根尖封闭性。方法　 79颗离体单根牙随机分为阳性对照 (2颗 )、阴性对照 (2颗 )及 5个实验组 (各 15颗 ) ,分别用不同的根充糊剂加牙胶尖以冷侧压法充填根管 ,通过染料渗入法检查根尖微渗漏。结果　所有根充糊剂充填后根尖部位均有微渗漏 ,Vitapex组的微渗漏值低于其他各组 ,差异有显著性 (P <0 .0 5 ) ,而其余各组结果差异无显著性 (P >0 .0 5 )。结论　各种根充糊剂充填后都不能完全封闭根尖孔 ,Vitapex的根尖封闭性优于其他各组。     

微波联合Vitapex糊剂治疗根尖周小囊肿的临床效果

目的探讨微波联合Vitapex糊剂治疗根尖周小囊肿的临床效果。方法对确诊为根尖周小囊肿的48例患者52颗患牙,采用微波烧灼囊腔壁及Vitapex糊剂加压注射入囊腔,牙胶尖加根充糊剂侧方加压根管充填等非手术方式治疗根尖周小囊肿,术后临床检查及拍摄X线片,随访1～3年,观察临床疗效。结果 48例患者52颗患牙,随访50颗,其中治愈为39颗,治愈率78%,好转为8颗,好转率为16%,总有效率为94%,失败为3颗,失败率为6%。结论微波联合Vitapex糊剂治疗根尖周小囊肿的效果满意。     

Cortisomol与Vitapex糊剂用于根尖周炎根充治疗的临床疗效比较

目的 比较Cortisomol糊剂和Vitapex糊剂充填根管治疗根尖周炎的术后反应及临床疗效,以帮助临床医师进行根充材料的选择。方法 选择205例215颗根尖周炎患牙,随机分为实验组(Cortisomol组)110颗牙和对照组(Vitapex组)105颗牙。常规根管预备后,分别采用Cortisomol糊剂、Vitapex糊剂加牙胶尖充填根管。观察术后1周内急症反应及2年的疗效。结果 二者1周内急症反应较轻,两组差异无显著性(P>0.05),术后2年复查,实验组成功率为93.6%,对照组成功率为84.8%,实验组疗效明显高于对照组,两组差异有显著性(P<0.05)。结论 Cortisomol糊剂疗效优于Vitapex糊剂,是目前根管治疗中较为理想的一种永久性根管充填材料。     

3种根充材料在一次法根管治疗中临床疗效观察

目的:比较三种根管充填材料一次法根充的临床疗效。方法:5 0 2个需根管治疗的患牙随机分为3组;分别采用Cortisomol糊剂加牙胶尖、Vitapex糊剂加牙胶尖、氧化锌糊剂加牙胶尖充填根管。观察术后1周内疼痛发生情况及1年后的疗效。结果:Cortisomol组和Vitapex组疼痛发生率较氧化锌组低,有显著性差异(P <0 .0 5 ) ;术后一年复查,Cortisomol组和Vitapex组总疗效好于氧化锌组,但无显著性差异(P >0 .0 5 )。根尖有暗影患牙的疗效Vitapex组好于Cortisomol组和氧化锌组,有显著性差异(P <0 .0 5 )。结论:Cortisomol糊剂和Vitapex糊剂充填根管可以有效减少一次性根管充填术后急症的发生,对根尖有暗影患牙的治疗Vitapex糊剂更有效。     

Vitapex根管充填糊剂治疗老年糖尿病患者窦道型根尖周炎的疗效

目的 观察Vitapex糊剂治疗老年糖尿病患者窦道型根尖周炎,观察治疗1周后的急症反应和2年后的临床疗效.方法 选择患有糖尿病且有窦道型根尖周炎的老年患者144例的225颗患牙,常规根管预备消毒后分为2组:A组72例116颗患牙使用Vitapex糊剂加牙胶尖充填根管,B组72例109颗患牙用Cortisomol糊剂加牙...     

Vitapex糊剂治疗根尖周炎疗效观察

目的探讨Vitapex糊剂治疗慢性根尖周炎疗效与氧化锌丁香性糊剂疗效观察。方法将255例根尖患牙随机分成2组。Vitapex实验组135例。根管内注入Vitapex糊剂后加牙胶尖致密充填;常规治疗组氧化锌丁香油糊剂 牙胶尖致密充填。结果治疗总有效率实验组91.85%,对照组82.5%。两组疗效有显著差异(P<0.05)。结论Vitapex糊剂在治疗慢性根尖周炎患牙疗效优于氧化锌丁香油糊剂     

Variation in periodontal referral in 2 regions in theUK

This study investigated the periodontal referral patterns of general dental practitioners (GDPs) in Northern Ireland (NI) and North West England (NWE). A questionnaire dealing with periodontal referral was sent to all 520 GDPs registered in NI and to 274 GDPs in NWE. A usable return was made by 355 (68%) in NI and 189 (70%) in NWE. The NI dentists made significantly more periodontal referrals (median 5, range 0-80) in the year preceding the survey than those in NWE (median 2, range 0-50), p<0.001. Distance was the only factor significantly related to the referral rate in both regions with those who practised more than 25 miles from a specialist referring significantly fewer patients in both regions. In NI, there was a trend towards increased periodontal referral by GDPs who had attended more postgraduate courses; however, in NWE, this was not the case. The GDPs in NWE were significantly less likely than those in NI to refer patients with medical conditions. It is concluded that there is considerable variation in periodontal referral both within and between the 2 regions studied. It is further concluded that in many cases, non-disease factors, such as the accessibility of the specialist service, have powerful effects on the decisions made by dentists and patients in these regions (NI and NWE) in relation to periodontal referral. Much of the variance in referral in North West England, as in Northern Ireland, remains unexplained.     

云南省五岁儿童乳牙龋病调查分析

目的：了解云南省５岁儿童乳牙龋齿患病情况。方法：随机抽取云南省三个城市三个农村的２１３２名５岁常住儿童,采用第二次全国口腔健康流行病学调查标准调查龋齿患病情况。结果：云南省５岁儿童乳牙患龋率为７５．７５％,龋均为４．４４,充填率仅为６．５７％,仅占构成比的４．３９％。结论：云南省５岁儿童乳牙龋齿患病率高,充填率低。儿童龋病防治应注重两个方面：１．加强对家长和教师的幼儿口腔卫生保健知识及方法的宣传。     

Changes in cyclooxygenase metabolities in experimental periodontitis in Macaca mulatta

The four principal metabolites of cyclooxygenase (CO) were examined during the progression of experimental periodontitis in the rhesus monkey Macaca mulatta. Thirty-two monkeys were divided in four disease-matched groups. Three groups were treated with flurbiprofen, a potent CO inhibitor, at either 0.027, 0.27 or 7.1 mg/kg/day delivered systemically by a subcutaneously-implanted osmotic mini-pump. We have previously described the findings indicating that flurbiprofen treatment significantly retarded clinical attachment loss (ALOSS), redness and radiographic bone loss (BLOSS). This investigation focuses on the changes in CO metabolites which occur during disease progression of ligature-induced periodontitis and on the dose-response relationship of flurbiprofen, as it relates to disease inhibition and the suppression of ARA metabolites within the crevicular fluid (CF). In untreated animals there was a statistically significant 3-fold increase in CF levels of prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) at 3 months, as compared to baseline, which positively correlated with increases in redness, bleeding, ALOSS and BLOSS. CF-PGE2 and TxB2 levels reached a 6-fold peak at 6 months and returned to baseline by 12 months. Flurbiprofen (Fb) prevented the 3-month rise in TxB2, but did not affect the increase in PGE2. At 6 months, Fb administration caused a dose-dependent inhibition of both PGE2 and TxB2. Probit analysis of the dose-response data revealed that the concentration of Fb which caused a 50% inhibition of CF-TxB2 level (the IC50 value for TxB2 synthesis) was approximately two logs lower than the IC50 value for PGE2 synthesis, i.e. TxA2-IC50 = 0.013 vs. PGE2-IC50 = 1.35 mg flurbiprofen/kg/d. The slopes of the PGE2 and TxB2 inhibition curves were identical, consistent with a similar mechanism or singular enzyme for the site of action of Fb inhibition of CO activity. However, the kinetics and sensitivity of Fb inhibition were significantly different for the CO activity responsible for TxB2 and PGE2 synthesis, perhaps due to different compartmentalization of CO within different cell types.     

Mast cells in masseter muscle in experimental bruxism in man

Three human subjects performed tooth grinding for 25 min, and after 20 h biopsies of the right and left masseter muscles were examined for their contents of mast cells. In comparison with specimens from a control group of three subjects, there was an increase of degranulating mast cells in muscles that had performed bruxism.     

Experience in using moradol in osteoplastic operations in oral surgery

Osteoplastic operations on the jaws were carried out in 19 patients aged 14-64 under moradol anesthesia. The mean length of the operation was 3 hours. The authors come to a conclusion that moradol in a dose of 0.3 mg/kg b. w. ensures adequate anesthesia, with a high level of analgesia persisting in the immediate postoperative period.