Direct pull of lateral cricoarytenoid muscle for unilateral vocal cord paralysis

CONCLUSION: Lateral cricoarytenoid muscle-pull surgery (LCA pull) is a safe and effective method for the treatment of unilateral vocal cord paralysis. OBJECTIVE: To evaluate the results of an improved method of LCA pull for unilateral vocal cord paralysis. MATERIAL AND METHODS: Thirteen patients with unilateral vocal cord paralysis underwent LCA pull between April 2003 and January 2004. A small window was made in the posterior lower part of the thyroid cartilage and 2-3 mm in a cranial direction to the lower edge of the thyroid cartilage. The inner perichondrium was carefully removed to expose the LCA muscle. A 4-0 nylon suture placed through the LCA muscle was pulled to adduct the arytenoid and was tied to the anterior lower part of the thyroid cartilage. All cases were treated by LCA pull alone. In all cases, the maximum phonation time was measured and an auditory evaluation was performed using the grade, roughness, breathiness, asthenia and strain scale. The airflow rate was measured in five cases. RESULTS: Vocal improvement was obtained in 11/13 cases (85%). One of the unimproved cases had cricoarytenoid joint ankylosis. No complications were observed.     

双蒂肌转入充填联合杓状软骨内移喉成形术治疗单侧声带麻痹

目的 探讨双蒂胸骨舌骨肌瓣转入声门旁联合杓状软骨内移治疗单侧声带麻痹的疗效.方法 不适合行喉返神经探查修复术的单侧声带麻痹19例.在甲状软骨板正中旁开0.5 cm裂开甲状软骨板,在杓状软骨内收固定的同时将带双蒂的胸骨舌骨肌瓣转入患侧声门旁内.治疗前后以电子喉镜、频闪喉镜、嗓音听评委主观评估、声学参数客观分析等评价治疗效果.结果 所有患侧声带膜部及声带突部术后即刻均明显内移,声带体积增大,发声时增大更为明显.术后2个月声门后裂隙消失6例,缩小13例;12个月后嗓音总嘶哑度评估:恢复正常6例,轻度声嘶12例,中度声嘶1例,较术前明显好转,采用等级资料数据秩和检验,差异具有统计学意义(z值为-4.062,P＜0.01).术后12个月的声门后裂隙、嗓音总嘶哑度与术后2个月比较无明显区别(P值均＞0.05).术后2个月及12个月声学客观指标的4个参数(基础频率、频率微扰、振幅微扰和谐噪比)平均值均明显小于术前,最长声时明显长于术前,差异均有统计学意义(P值均＜0.05).术后12个月与2个月比较上述参数差异均无统计学意义(P值均＞0.05).结论 双蒂胸骨舌骨肌充填联合杓状软骨内移喉成形术治疗不适合行喉返神经探查修复术的单侧声带麻痹患者的创伤小,无排异反应,远期效果较稳定.     

CO2激光单侧杓状软骨次全切除术治疗双侧外展性声带麻痹

目的　探讨CO2 激光单侧杓状软骨次全切除术治疗双侧外展性声带麻痹手术的适应证及临床意义。方法　支撑喉镜下对 8例双侧外展性声带麻痹伴呼吸困难的患者实施了CO2 激光单侧杓状软骨次全切除术和手术创面黏膜吻合术。其中 ,继发于双侧甲状腺切除术 5例 ,外伤所致双侧外展性声带麻痹 2例 ,原因不明 1例。术前接受气管造口术 5例 ,气管切开术 1例。术后通过纤维喉镜检查患者新建声门裂的通气情况 ,发音质量主观评估由患者本人和医疗小组共同完成。结果8例患者术后均恢复了满意的呼吸功能 ,发音质量均无明显下降 ,平均气管套管拔除时间为 44 2d。术后随访 5～ 43个月 ,没有出现误吸和再狭窄等并发症。结论　支撑喉镜下CO2 激光单侧杓状软骨次全切除术和创面黏膜吻合术简单易行 ,创面小 ,术后愈合快 ,可避免肉芽组织增生和瘢痕形成所导致的声门区再狭窄 ,患者的呼吸和发音功能均得到了满意的恢复和保留     

支撑喉镜下CO2激光杓状软骨切除术治疗双声带外展麻痹

目的　探讨支撑喉镜下CO2 激光显微杓状软骨切除术治疗双声带外展麻痹的手术方法、疗效和适应证。方法　 1994～ 1998年收治双声带外展麻痹患者 8例 ,其中 3例曾在外院经颈外进路手术失败 ,全部术前行气管切开术。参照并改良Ossoff窥镜下杓状软骨切除术 ,汽化杓状软骨前部 ,包括声带突和部分肌突 ,一小部分室带及声带后端 ,保留粘软骨膜并缝合切口 ,以消灭创面 ,双侧分次手术。结果　术后无肉芽滋生 ,无误吸 ,保留发音功能。 5例拔管 ,2例日间堵管、因睡眠时喉鸣未予拔管 ,1例等待对侧手术。随诊 6个月～ 3 5年。结论　本方式弥补了单纯窥镜及外科手术不足 ,如粘膜出血、水肿、操作困难等 ,而具备显微外科精细、准确的特点。术后反应轻微 ,保留发音功能。并可作为杓状软骨切除术或神经再支配手术失败后的补充手术     

红宝石激光同期杓状软骨内侧切除治疗双侧声带麻痹

目的 :探讨支撑喉镜下以红宝石激光同期切除双侧杓状软骨内侧治疗双侧声带麻痹的疗效。方法 :全部患者均行气管切开插管麻醉 ,以红宝石激光同期切除双侧杓状软骨的内侧。结果 :无手术并发症。全部患者随访 3～ 13个月 ,呼吸平稳 ,喉内无瘢痕粘连 ,发音明显好转 ,声门呼吸部较术前扩大≥ 4mm。结论 :以红宝石激光同期行双侧杓状软骨内侧切除治疗双侧声带麻痹是切实可行的。     

A "fenestration approach" for arytenoid adduction through the thyroid ala combined with type I thyroplasty

OBJECTIVE: To develop and evaluate the voice outcomes of an approach of arytenoid adduction (AA) through a fenestration of the thyroid ala for unilateral vocal cord paralysis. STUDY DESIGN: Twelve consecutive patients with severe unilateral vocal cord paralysis, whose maximum phonation times (MPTs) were less than or equal to 5 seconds, underwent laryngoplasty using an approach of AA performed through a fenestration of the thyroid ala combined with type I thyroplasty. METHOD: Two surgical windows were made in the lower part of the thyroid ala. The anterior window was for typical type I thyroplasty, and the posterior window was for AA. AA was performed by pulling the lateral cricoarytenoid muscle (LCA) (5 patients) or muscular process (7 patients) through the posterior fenestration in the contractile direction of the LCA without releasing the cricoarytenoid joint. The operation was performed under local anesthesia with sedation except in two patients who underwent general anesthesia using a laryngeal mask. The vocal cord medialization was confirmed endoscopically during the operation. For all patients, the MPT and mean airflow rate (MFR) were measured before and after the operation. The postoperative voices were analyzed using shimmer and jitter. RESULT: All patients achieved a MPT of over 12 seconds. The MFR, which ranged from 340 to 1902 mL/second before the operation, improved to less than 200 mL/second, except in one patient whose MFR was 210 mL/second. Shimmer and jitter improved significantly after the operation. Perceptual evaluation using the GRBAS (grade, roughness, breathiness, aesthenia, strain) scale also improved significantly. CONCLUSION: A fenestration-based approach simplified the combination of AA and type I thyroplasty because the two treatments could be performed in the same operating field and provided good voice improvement. Pulling the AA braid in the contractile direction of the LCA and endoscopic vocal cord observation during surgery may have contributed to the positive results.     

A Study of incidence and etiopathology of vocal cord paralysis

Vocal cord paralysis is not a disease per se but is considered as a sign of underlying disease process that may be congenital or acquired, unilateral or bilateral, sudden or gradual in onset, and may occur at any age from cradle to the grave. This study vas carried out to know the incidence and etiopathology of vocal cord paralysis.The incidence was 0.42% or 42 per ten thousand new patients seen. Most patients presented in the 5th and 6th decades (77.2%). Males outnumbered females in the ratio of 3:1. The most common symptom of vocaL cord paralysis was hoarseness of voice alone(83.6%.).Onset of symptoms was gradual in 60% of cases.Left vocal cord was almost twice more commonly (61.9%)involved than the right one(38.1%).Idiopalhic group constituted 38.18% of patients followed by neoplaslic diseases 29.09oc.     

An analysis of vocal cord paralysis before and after Teflon injection using combined glottography

Combined glottography shows clinical potential but has only had limited use in monitoring laryngeal function before and after surgery. Eight patients undergoing Polytetrafluoroethylene (Teflon) injection for unilateral vocal cord palsies had pre-and post-operative combined glottography performed. Grossly abnormal waveforms pre-operatively confirmed poor glottic closure and irregular vibratory cycles. Analysis was difficult. Post-operatively all patients had a marked improvement in voice. Combined glottography showed a clear recovery of the waveforms towards normal with resumption of the two-mass model of glottal movement. Analysis was greatly simplified. Objective records were produced.     

声带麻痹病因分析和治疗方法的探讨

目的：寻找声带麻痹的病因和有效的治疗方法。方法：分析65例声带麻痹患者的临床资料，65例患者均经间接喉镜、动态喉镜或电子喉镜检查；其中31例行杓状软骨拨动术治疗。结果：由颈、胸部肿瘤引起声带麻痹14例；感染引起9例；颈、胸、腹部手术引起16例；气管插管引起12例；胃管插管引起3例；不明原因11例。治疗后声带麻痹消失37例，好转1例，有效率为58．46％；无效27例。结论：临床上对声音嘶哑的患者，应进行常规的间接喉镜、动态喉镜或电子喉镜检查。对有声带麻痹的患者应尽早在间接喉镜、直接喉镜或支撑喉镜下行杓状软骨拨动术。     

Combination of direct pull of lateral cricoarytenoid muscle and thyroplasty type I for severe unilateral vocal cord paralysis

Techniques and the outcome of our approach that combined two operations, a direct pull of the lateral cricoarytenoid muscle (LCA-Pull) and Isshiki's thyroplasty type I are reported. LCA-Pull is very simple and allows natural adduction of arytenoid by pulling LCA. The subjects were five patients whose maximal phonation time (MPT) were under 5 seconds. All patients achieved MPT over 13 seconds. Mean flow rates (MFR) varied from 340ml/s to over 1000 ml/s before the operation. In all patients, the post operative MFR improved to under 150 ml/s. Sometimes severe unilateral vocal cord paralysis requires both arytenoid adduction and medialization thyroplasty to obtain good voice. Combination of LCA-Pull and thyroplasty type I is very effective for severe case, and could be done in the same operating field by creating an additional window in the thyroid ala.     

Teflon injection for unilateral vocal cord paralysis and its effect on lung function

We present a prospective analysis of the lung function of 22 patients with unilateral vocal cord paralysis before and after Teflon injection. In the majority of patients the vocal cord paralysis was caused by an underlying malignant condition. Full spirometric and flow-volume loop studies demonstrated an increase in airway resistance after Teflon injection which was not clinically evident. The improvement in symptom score for aspiration was greater than that for dysphonia. Keywords unilateral vocal cord paralysis Teflon injection airway resistance     

Quality of life measures and predictors for adults with unilateral vocal cord paralysis

Objective/Hypothesis: To investigate the quality of life (QoLF) status of Taiwanese adults with unilateral vocal cord paralysis (UVCP). Study Design: A prospective, QoLF survey in a tertiary referral voice center. Methods: Fifty‐five consecutive UVCP patients were evaluated with Medical Outcome Study Short Form‐36 (SF‐36) Health Survey and the voice outcome survey at entry. Results: UVCP patients have significantly lower scores in all eight SF‐36 subscales (P < .05) than do normative Taiwan adult population, particularly in role functioning‐physical problems, social functioning, and role functioning‐emotional problems. Shimmer parameter is a robust and consistent predictor for bodily pain (β = ?20.8), role functioning‐emotional problems (β = ?27.9), and social functioning (β = ?20) general health dimensions. Shimmer is also predictive of UVCP‐related total voice outcome survey score (β = ?8.6, P < .05). Conclusions: UVCP can seriously compromise phonation, swallowing, and social functions; thus significantly impacting a patient's general health status. Voice physiological function is also a QoLF outcome indicator.     

Voice and vocal fold position in men with unilateral vocal fold paralysis

The paralyzed vocal fold positioning and the degree of dysphonia are important inputs when one is deciding upon treatment options for unilateral vocal fold paralysis (UVFP).ObjectiveTo check voice characteristics and paralyzed vocal fold position in men with UVFP.Materials and MethodsThis is a retrospective historical cross-sectional cohort study, with data from 24 men with UVFP with mean age of 60.7 years, submitted to voice assessment by three speech therapists and three ENT physicians used laryngeal images to classify the position of the paralyzed vocal fold.ResultsThe paralyzed vocal fold was found in the paramedian position in 45.83% of the cases; in the intermediary position in 25%; lateral in 20.83%, and it was in the median position in 4.16%; the dysphonia resulting from the UVFP was characterized by moderate hoarseness, roughness and stress in the voice; breathiness (most had severe breathiness); weakness and instability(mostly mild); the position of the paralyzed vocal fold had a significant influence on the general degree of vocal deviation.ConclusionThe general degree of dysphonia is associated with the paralyzed vocal fold position; dysphonia is characterized by hoarseness, breathiness, roughness and stress of moderate to severe levels.     

成人单侧声带麻痹病因及治疗现状分析

目的探讨成人单侧声带麻痹的病因及治疗现状。方法回顾性分析55例成人单侧声带麻痹患者的临床资料,比较不同侧别、不同性别声带麻痹的病因有无差异,并电话回访了解患者的治疗现状。结果成人单侧声带麻痹男性多见(37/55,67.27 %),左侧为主(43/55,78.18 %),病因以颈、胸部肿瘤为首(27/55,49.09 %),其次为特发性声带麻痹(22/55,40 %)。不同侧别声带麻痹的病因差异无统计学意义(χ²=0.610,P=0.731),不同性别患者声带麻痹的病因差异有统计学意义(χ²=8.939,P=0.011)。颈、胸部肿瘤患者中放弃治疗者居多(20/27,74.07 %),特发性声带麻痹中部分患者可自愈(6/22,27.27 %)。结论成人单侧声带麻痹男性多于女性,左侧多于右侧。成年人单侧声带麻痹的病因以颈、胸部肿瘤为主,多为恶性,且肿瘤分期晚,大部分患者放弃了后续治疗。不同侧别的患者病因在临床上无差异。不同性别患者的病因在临床上存在差异,男性单侧声带麻痹的首位病因为颈、胸部肿瘤,而女性则多为特发性声带麻痹。部分特发性单侧声带麻痹患...     

Voice quality improvement after management of unilateral vocal cord paralysis with different techniques

The aim of this study was to objectively evaluate the voices of patients suffering from unilateral vocal cord paralysis, before and after endoscopic augmentation and thyroplasty. In the past, we used injectable Teflon to treat this condition; later techniques included collagen injection and Isshiki thyroplasty. In the last 7 years, preferred treatment methods have included Bioplastique injection and lipoaugmentation of the vocal cords as well as medialization thyroplasty using a titanium implant according to Friedrich. Pre- and postoperative data was evaluated and compared to 25 patients. Appropriate glottic closure of the vocal cords was achieved in every case, in most cases after the first intervention. We used voice range profile measurements to evaluate the results. An objective evaluation was performed using the Friedrich dysphonia index. Significant improvements were found: the dysphonia index decreased in every case, from an average of 2.47, preoperatively, to an average of 1.18 postoperatively. In agreement with earlier studies, voice pitch range was the only parameter that not significantly improved. There was no statistical difference between the lipoaugmentation and thyroplasty according to Friedrich. We concluded that both endoscopic methods and thyroplasty can be used to achieve an optimal result. Cases must be evaluated individually so that the best technique, or combination of methods can be determined.Presented at the 5th ELS Congress in Lisbon on 10-13 July 2004     

不同干预时间进行声带注射对甲状腺术后单侧声带麻痹的临床疗效

目的甲状腺手术后导致的单侧声带麻痹（UVCP）影响患者的声音质量和生活质量,喉内声带注射可以有效地提高患者的声音质量,本研究观察术后不同时间进行声带注射治疗UVCP的疗效。方法回顾分析2017年1月—2019年4月湘雅二医院耳鼻咽喉头颈外科就诊的因甲状腺手术后UVCP早期（1个月内）或晚期（6个月以上）行声带注射喉成型的患者31例。所有患者均行局麻电子喉镜下颈外径路透明质酸声带注射喉成型术,其中18例在术后1个月内进行声带注射（A组）,13例患者在术后6个月以上进行声带注射（B组）。对所有患者治疗前后进行动态喉镜、嗓音分析、GRBAS评估、嗓音障碍指数量表（VHI 10）测评。对比两组患者治疗前后各组数据。结果两组患者治疗前临床特征、嗓音分析结果、GRBAS评估得分、VHI 10测评得分差异无统计学意义。两组患者注射后1个月内复查动态喉镜均可见声带闭合良好,B组有4例患者患侧声带未见明显黏膜波。A组注射患者VHI 10量表评分、MPT与B组患者差异无统计学意义; GRBAS评估得分、jitter、shimmer均低于B组。结论甲状腺手术后UVCP患者早期行声带注射治疗效果优于晚期注射,其原因可能是声带长时间失去接触性刺激和失神经性营养导致的声带功能层次的损伤。     

Influence of aging and sex on voice parameters in patients with unilateral vocal cord paralysis

OBJECTIVES: The objective of this study was to investigate influences of aging and sex on different voice parameters in patients with unilateral vocal cord paralysis (VCP). STUDY DESIGN: Retrospective review of patients with unilateral VCP. MATERIALS AND METHODS: Forty-seven patients, 22 males, 25 females (24-85 years), were enrolled in the study. The diagnosis of VCP was established by videolaryngostroboscopy. The acoustic parameters of jitter, shimmer, degree of subharmonic, noise to harmonic ratio, fundamental frequency, and maximal intensity were measured. The auditive voice analysis included roughness, breathiness, and hoarseness. Statistical analysis involves Pearson's bivariate correlation coefficients and two-way analysis of variance with interaction variables. RESOLUTION: After unilateral VCP in the elderly, some sex- and age-related differences in the restriction of the voice can be documented. CONCLUSION: In general, the investigated voice parameters showed similar tendencies to those in otherwise healthy aging persons.