太极扣附着体在游离端牙列缺损修复中的应用

目的探讨太极扣附着体在游离端牙列缺损修复中的应用效果。方法结合24例应用太极扣附着体修复的牙列缺损患者,修复肯氏Ⅰ类缺损9例,肯氏Ⅱ类缺损15例。对其进行满意度、固位性能、咀嚼效能、舒适程度、美观性、摘戴方便程度等调查。通过患者主诉、临床X线片检查基牙的牙体、牙周状况等方面观察其修复效果。其中6例较以前曾使用过的传统可摘局部义齿明显感觉舒适、美观。有1例因基牙龈合距离低于5 mm,颌力过大,致义齿断裂;其余使用良好。结果经12～24个月的观察,24例太极扣附着体在各方面都比传统修复体有明显提高。结论太极扣附着体在修复肯氏Ⅰ、Ⅱ类牙列缺损时是一种简单可靠、成本低、易于推广应用的附着体。     

太极扣附着体义齿的临床应用

目的:评价一种冠外精密附着体义齿修复牙列缺损的临床效果。方法:采用太极扣附着体17副,分别修复10例牙列缺损患者。其中肯氏Ⅰ类缺损7例,肯氏Ⅱ类缺损3例,对临床修复效果进行分析,并与同期进行的、同类别缺损RPD对照。结果:经6个月观察,89%以上患者认为附着体义齿美观、舒适、稳固、易适应、咀嚼有力。对61颗基牙复查结果显示,基牙无叩痛、松动。无根尖周病变及牙槽骨吸收,其中10颗基牙有龈缘充血水肿现象。附着体上少量牙石沉积,对照组58颗基牙中23颗有龈缘充血水肿。结论:太极扣精密附着体义齿能达到良好的修复效果。     

OT—CAP、OT—BOX附着体在可摘局部义齿中的应用

肯氏Ⅰ ,Ⅱ类牙列缺损仅余留前牙或双尖牙齿，采用常规卡环式固位体制作可摘局部义齿往往对基牙损害较大 ,并且义齿的稳定性不理想 ,卡环的暴露也影响了美观 ;此外 ,一些仅余留少数残冠、残根而临床牙冠短的牙列缺损 ,不宜进行人造冠修复 ,采用一般覆盖义齿修复因固位稳定性较差 ,因而功能较难恢复。笔者自１９９７年起采用ＯＴ＿ＣＡＰ ,ＯＴ＿ＢＯＸ附着体 ,为上述牙列缺损患者制作了根上附着体的覆盖义齿和固定—可摘联合义齿共２０件 ,临床应用效果良好 ,现报道如下。１．一般资料门诊病人２０例 ,男１５例 ,女５例 ;年龄３５～６７岁 ,…     

太极扣精密附着体在肯氏Ⅱ类牙列缺失修复中的临床应用

目的:介绍太极扣精密附着体修复肯氏Ⅱ类牙列缺失的适应证选择、临床使用注意事项及疗效观察。方法:选择26例第一及第二磨牙缺失的肯氏Ⅱ类牙列缺失患者,利用太极扣附着体进行单侧修复,追踪随访,分别从主观感觉、口腔检查和X线检查观察其修复效果。结果:临床随访1.0～2.5年,25例患者义齿固位良好,行使功能佳,基牙及牙周组织健康,1例折断,成功率95%。结论:太极扣精密附着体在肯氏Ⅱ类牙列缺失修复中取得较好疗效,值得推广。     

按扣式附着体义齿修复游离端牙列缺损的临床应用

目的：应用按扣式精密附着体义齿修复游离端牙列缺损,评价其临床修复效果。方法：采用Ceka按扣式附着体,为69例游离端牙列缺损患者制作69件精密附着体义齿,观察修复效果。结果：随访1-7年,88%以上患者感觉义齿美观、舒适、固位稳定性好、易适应、咀嚼功能好。未见基牙松动,仅有1颗基牙发生根尖周炎,2颗基牙出现颈部继发龋。结论：Ceka按扣式附着体义齿用于游离端牙列缺损修复,效果良好。     

快套式精密附着体进行(牙合)重建的应用研究

目的:探讨快套式附着体固位可摘义齿修复重度牙齿磨耗伴牙列缺损 (双侧游离端缺失 )的临床效果。方法:对 8例患者 5 1颗基牙 ,应用快套式冠外附着体 16件 ,经过半年至 2年时间的临床结果进行分析。 结果 :8例患者咀嚼能力明显改善 ,该修复体具有治疗性咬合板和牙周夹板的作用 ,义齿固位稳定性及美观效果好 ,基牙牙槽骨无明显吸收。 结论:快套式附着体固位可摘义齿是一种固定 -活动联合修复体 ,兼有固定和活动义齿的优点 ,值得临床推广应用。     

冠外附着体义齿修复双侧游离缺失的临床应用

目的观察Ceka冠外精密附着体在双侧游离端牙列缺损修复中的临床疗效。方法两系列Ceka冠外精密附着体为35例双侧磨牙游离端缺失的患者制作附着体义齿，临床复诊0．5～3年，从主观感受、临床检查和X线检查三方面观察其修复效果。结果患者进行双侧冠外精密附着体义齿修复后美观效果满意，异物感小，固位稳定效果好，咀嚼有力，其中27例相较以前可摘活动义齿明显感觉舒适，修复效果满意。30例患者基牙，牙龈，牙槽嵴粘膜健康。1例患者在使用1年后出现阳性附着体对应处咬合面断裂。1例患者2年后出现缺牙区牙槽骨吸收。结论Ceka系列冠外精密附着体是一种较理想的游离牙列缺损修复固位体。     

SD球帽式附着体义齿的临床应用研究

目的：探讨SD球帽式附着体义齿在肯氏I类牙列缺损中的修复。方法：采用SD球帽式附着体为30例患者制作36件义齿,并经过6个月至3年半的临床随访。结果：患者对义齿的美观及功能均满意,临床观察未见基牙根周骨质吸收。结论：该种附着体在肯氏I类牙列缺损修复中具有良好的临床应用价值,值得推广。     

太极扣附着体在游离缺失义齿修复中的应用

目的观察太极扣附着体(Sterngold附着体)在单双侧游离缺失义齿修复中的应用效果。方法采用太极扣-RV和微型太极扣附着体为Kennedy Class分型Ⅰ类和Ⅱ类牙列缺损各14例患者制作可摘局部义齿。随访6～24个月,对两组义齿的固位效果、咀嚼功能和使用满意度进行评估。结果28例患者的太极扣附着体义齿使用均正常,义齿的固位力、稳定性及咀嚼功能、基牙和牙槽嵴吸收均表现良好,患者满意或基本满意。Kennedy Class Ⅰ类患者的修复效果好于Ⅱ类患者。结论Sterngold附着体适用于kennedy Class Ⅰ类和Ⅱ类单、双侧游离缺失的义齿修复,可为其提供足够的固位力,且稳定性好,口感舒适。     

精密附着体义齿修复游离牙列缺损10例效果观察

目的:探讨精密附着体义齿修复游离牙列缺损的临床疗效。方法:对10例游离牙列缺损的患者,采用精密附着体义齿修复,追踪3~24个月,评价修复后的功能和外观、固位及稳定,咀嚼效率及对基牙的影响。结果:10例患者对固定和稳定,咀嚼效率的效果都很满意,对功能及美观满意9例,基本满意1例;松动牙基4例均满意。结论:精密附着体义齿是目前修复游离牙列缺损的最佳修复方式,具有广泛应用的前景。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.