模拟定位机导引下经皮细针吸取活检对肺部肿块的诊断意义

目的 探讨模拟定位机导引入经皮细针吸取活检对肺部肿块的诊断意义。方法 应用模拟定位机导引下经皮细针吸取肺部肿块活检对１７５例肺部肿块的诊断价值进行分析。结果 共获得细胞学标本１６９例,活检成功率９６．６％（１６９／１７５）,诊断阳性率９２％（１６１／１７５）,并发症率６．３％（１１／１７５）,假阴性率４．７％（８／１６９）。本组恶性肿瘤占９０．１％（１４５／１７５）,可进行病理分类７７．９％（１１     

模拟定位机下经皮肺周围型肿块细针穿刺细胞学检查的价值

肺周围性肿块样病变 ,是临床上常见的影像学征象 ,也是多种疾病在肺部的表现。为了明确诊断肺周围肿块的性质 ,以往一般依靠痰细胞学 ,纤支镜检查等 ,仍有不少病例难以及时确诊。近十年来 ,经TNA的开展为临床提供了一种可靠的诊断手段[1] 。本组自 1997年 3月～ 2 0 0 1年 10月期间在模拟定位机引导下经皮肺周围型肿块细针穿刺细胞学检查 30例 ,结果满意。　　 材料和方法一　研究对象　本组 30例 ,男性 2 0例 ,女性 10例 ,年龄 15～ 79岁 ,平均 4 7岁。KPS评分≥ 70。全部病例均经影像学检查 (胸部X线及CT)发现有胸内肿块 ;病灶最大者…     

细针吸取细胞学检查乳腺肿块91例临床分析

目的评价细针吸取细胞学检查在乳腺肿块诊断价值。方法1998年~2002年用细针吸取细胞学检查诊断乳腺肿块91例对其结果进行回顾性分析。结果乳腺良性肿瘤和恶性肿瘤准确率分别是90%和100%。结论细针吸取细胞学检查快速简便,病人无痛苦,对术式选择有较大的价值。     

模拟定位机导向经皮肺穿刺周围型肺部病灶针吸活检术的临床应用

目的 :探讨模拟定位机导向经皮肺穿刺针吸活检术对周围型肺部病灶的诊断意义。方法 :1998 10～ 2 0 0 1 5期间随机选择 45例经纤维支气管镜和痰细胞学检查未能明确病理的周围型肺部病灶的病例 ,经CT扫描片的测量 ,在模拟定位机导向下 45次使用国产秦氏针进行针吸活检与细胞学检查。结果 :鳞癌 2 3例 ,腺癌 11例 ,小细胞癌 4例 ,未定型 2例 ,抗酸杆菌 4例 ,炎性细胞 1例 ,经手术 (2 0例 )与 1年以上随访 (2 5例 )证实。肺部病灶的确诊率为 88 9%。结论 :模拟定位机导向经皮肺穿刺周围型肺部病灶针吸活检是一简便而又可靠的诊断方法 ,对周围型肺部病灶的诊断具有重要价值。     

涎腺肿块的细针吸取细胞学诊断分析

目的通过对细针吸取涎腺肿块细胞图片的形态学分析,研究细针吸取细胞学在涎腺肿块中的诊断价值。方法对179例涎腺肿块疾病行细针吸取细胞学涂片,用显微镜对涂片进行形态学分析,作出细胞学诊断,并与术后病理学诊断作比较。结果本组病例细胞学诊断的总体分类准确率为93.2％,特异性为94．3％;良性病变准确率为95％,特异性为94．4％;恶性肿瘤准确率为83．3％,特异性为88．2％。结论细针吸取细胞学对涎腺肿块的诊断具有操作简便、诊断快速、准确率高等优点,可作为涎腺肿块疾病的常规诊断方法应用。     

经皮细针胸腔肿块穿刺细胞学诊断

目的 经皮细针胸腔肿块穿刺做细胞学诊断。方法 193例经皮细针胸腔肿块穿刺细胞学诊断。结果 诊断总符合率92.2％,敏感性93.3％,特异性98.4％,恶性肿瘤的诊断符合率91.3％,敏感性92.7％,特异性98.7％。鳞癌和腺癌的符合率分别为65.6％和76.5％。结论 经皮细针胸穿细胞学诊断率高,腺癌和鳞癌分类较不理想。提高正确诊断性的关键是获取足够的细胞量和训练有素的细胞学者注意结合临床表现。     

细针穿刺细胞学检查在乳腺肿块诊断中的意义

通过对826例乳腺肿块细针穿刺细胞学(FNAC)检查与临床组织病理的比较,分析两者之间的相关性,同时对62例两者之间不符病例进行回顾性分析。     

模拟定位机下行周围型肺肿块穿刺活检分析

肺癌是最常见的恶性肿瘤,近10年来,世界各国肺癌的发病率和死亡率都有明显上升趋势.早期明确的诊断对肺癌的治疗至关重要,自1997～2002年我们在模拟定位机下对位于肺周围肿物结节性病变行经皮穿刺肺活检术,现报告如下.     

细针吸取细胞学在乳腺肿块诊断中的应用

目的 探讨细针吸取细胞学对乳腺肿块的诊断价值,分析漏诊误诊原因.方法 总结493例乳腺肿块细针吸取细胞学资料,其中303例与术后病理组织学结果对照.结果 303例乳腺肿块病人,恶性肿瘤131例,良性172例,而细针吸取细胞学对诊断乳腺肿块良恶性的敏感性为96.2﹪,假阳性率为0,假阴性率为3.8﹪,准确率为98.3﹪.结论 细针吸取细胞学对乳腺肿块术前诊断具有重要价值,细胞学医生应详细询问病史,结合临床资料及免疫组化标记等进一步提高其准确性,避免漏诊误诊发生.     

针刺快速细胞学诊断在肺及纵隔肿瘤手术中的应用

目的：探讨细针穿刺细胞学诊断在肺及纵隔肿瘤手术中的应用价值。方法：对79例肺部肿块、12例纵隔肿瘤术中应用细针穿刺细胞学诊断，并与术后病理结果对照。结果：肺部肿块细胞学诊断准确率为97．5％（77／79），细胞类型诊断准确率为93％（55／59），纵隔肿瘤细胞学诊断准确率为100％。结论：对未定性的肺及纵隔肿瘤本操作具有容易、安全，快速和无非发症的优点，可避免盲目进行扩大肺组织切除，尽最大限度保留健康肺组织。     

乳腺肿物细针穿刺细胞学诊断的研究

目的　对细针穿刺细胞学诊断在乳腺肿物穿刺中的应用进行评价。方法　细针穿刺乳腺触及到实变处肿物吸取组织细胞涂片 ,采用瑞氏 -姬姆萨复合染色 ,显微镜下观察细胞排列、结构、背景特点、细胞形态等方面对乳腺肿物良恶性判定 ,并与病理组织学诊断进行对比分析。结果　乳腺肿物 3 3 2 5例细针穿刺 ,总准确率为 98 1% ;65 5例乳腺癌的诊断准确率为 10 0 % ;在部分良性病例 (乳腺纤维腺瘤 )的诊断准确率为 88% ;疑癌 94% ,描述性报告 7%确诊为乳腺癌。结论　细针穿刺细胞学诊断对于临床诊断良恶性病变有独到价值。且对恶性病例诊断更为可靠。此诊断技术简便 ,费用低 ,值得推广应用。     

模拟定位器引导经皮穿刺肺活检(附19例报告)

1978年4月至1984年2月我们使用模拟定位器引导,对19例周围型肺癌进行经皮肺针吸活检(PALB),获阳性病理诊断12例,阳性率63.2％。其中腺癌5例、鳞癌4例、小细胞癌1例,癌(未分类)2例。PALB阳性组12例中,经药物治疗7例均在3～11月内死亡;采取手术治疗5例,术后病理学诊断与PALB诊断相同。PALB阴性组7例均行手术治疗,术后病理诊断为腺癌3例、鳞癌3例、支气管肺泡癌1例。本方法对肺癌早期诊断为一有用途径。     

Accuracy of Fine Needle Aspiration Cytology in Head and Neck Masses

In ENT clinical practice patients with neck swelling is a common presentation. To know their exact nature a simple, sensitive and diagnostic tool is required to prevent unnecessary costlier investigation and corresponding treatment. Fine needle aspiration cytology (FNAC) is a very safe, sensitive and diagnostic tool. This study was done to know the diagnostic accuracy, sensitivity and specificity of the FNAC in head and neck masses. Present prospective study was done in 179 patients of head and neck masses which were subjected to FNAC and their results were later correlated with histopathological examination report (HPR) wherever available. Out of 179 FNAC, HPR available only in 152 cases. In present study 104 cases (58.10 %) of lymph node, 35 cases (19.55 %) of thyroid gland, 17 cases (9.49 %) of salivary gland, 12 cases (6.70 %) of soft tissue and 11 cases (6.14 %) of miscellaneous swellings were present. The sensitivity, specificity, positive predictive value and negative predictive value of present study were 81.8, 95.0, 81.8 and 95.0 % respectively. The accuracy was 92.10 %.     

Accuracy of Fine Needle Aspiration Cytology from Breast Masses in Thailand

Objective: To evaluate the accuracy and diagnostic performance of fine needle aspiration FNA cytology indiagnoses of breast masses. Methods: Women who had FNA diagnoses for breast masses and underwentsubsequent histopathologic evaluation during January 2003-December 2006 were accessed from the archive ofthe Anatomical Pathology Department of our institution. Cytologic diagnoses were classified as unsatisfactory,benign, atypical probably benign, suspicious probably malignant, and malignant, and were compared to thehistopathologic diagnoses obtained from core needle biopsy, excisional biopsy, or mastectomy to give an assessmentof the diagnostic performance of FNA. Results: A series of 190 breast masses were identified during the studyperiod. The FNA cytological diagnosis was unsatisfactory due to inadequate specimens in eight cases (4.2%).The diagnoses in the remaining 182 cases were: benign lesions in 98 (53.9%); suspicious for malignancy in 31(17.0%); and malignant in 53 (29.1%). From the subsequent histopathologic diagnoses, 6/98 cases of benigncytology turned out to be malignant lesions (false negatives); 22/31 cases of suspicious cytology were trulymalignant while the other nine were benign; and only 1/53 with malignant cytology was benign (false positive),the lesion being a fibroadenoma . The overall accuracy, sensitivity, specificity, positive predictive value, andnegative predictive value were 91.2% (95% confidence interval [CI], 87.6%-94.8%), 92.5% (95% CI, 88.7%-96.3%), 90.2% (95% CI, 85.9%-94.5%), 88.1% (95% CI, 83.4%-92.8%) and 93.9% (95% CI, 90.4%-97.4%),respectively. Conclusions: FNA cytology is highly accurate for diagnosis of breast masses. However, the clinicianshould correlate FNA cytological results with physical examination and imaging findings to prevent false negativeand false positive events and to obtain optimal management for their patients.     

CT引导下经皮肺细针抽吸活检术的临床应用价值

目的评价CT引导经皮肺细针抽吸活检术的临床应用价值。方法对110例CT引导下经皮肺细针抽吸活检术，病理检查证实93例。结果93例患者中，与病理检查相吻合的肺癌85例，穿刺确诊77例，8例为肺部良性病变。诊断灵敏度90．6％，特异度100．0％，诊断准确率91．4％。并发气胸9．1％，肺内出血10．9％，均自行吸收。结论CT引导经皮肺细针抽吸活检术临床应用准确性较高，并发症较少，有助于肺部病变的诊断。     

模拟机定位经胸细针肺穿刺诊断肺癌(附100例报告)

自1986年1月至1988年6月,共进行模拟机定位经胸细针肺穿刺诊断肺癌100例。穿刺成功率90%。未出现严重并发症。模拟机引导定位穿刺法诊断肺癌有许多优点,如定位精确、并发症少并有很高的阳性率。无论对周围型肺癌还是中心型肺癌,均可获得较高的穿刺成功率。     

Percutaneous Lung Aspiration Biopsy: A Comparison Between Two Fine Needles

Fine needle lung aspiration biopsy is now a well established method of obtaining tissue for histopatho-logical diagnosis. It is fast, simple and reliable, and has a very low complication rate. We report our experience using two fine needles, the Turner and the EZ-EM Cut-Biopsy needles, comparing their yield and complication rates. We found that both needles had comparable diagnostic yields (65% with the Turner, and 71% with the EZ-EM) and complication rates. We also found that in most cases, aspirates alone were sufficient for diagnosis, and that obtaining tissue cores with larger bore EZ-EM needles did not significantly influence the diagnostic outcome. We conclude that both the Turner and the EZ-EM needles are equally effective and safe in percutaneous lung aspiration biopsy. The least traumatic needle should be used except when the cytological diagnosis is nonspecific inflammatory cells or inadequate, in which case a repeat with a cutting needle is advised to obtain a core of tissue.     

CT引导下经皮肺穿活检的临床应用

目的　探讨CT引导下经皮肺穿活检的临床意义。方法　 96 0例患者 ,病变直径 1.9～ 14cm ,左肺 471例 ,右肺 489例 ;全部在CT引导下经皮穿刺活检。结果　穿刺成功率为 92 .91%,933例得到了最后的诊断 ,其中肺癌 6 5 3例 ,转移瘤 2 4例 ,结核 179例 ,肺内炎症 77例 ;93例出现了气胸 ,占 0 6 %,17例出现了咯血。结论　CT引导下的肺穿刺活检术是一个安全、并发症少、准确性高的诊断方法。