泛影葡胺子宫输卵管造影30例

泛影葡胺子宫输卵管造影３０例董蓓，刘西元我科近３年来，使用泛影葡胺行子宫输卵管造影术，取得满意效果，报道如下。ｌ资料与方法本组３０例。年龄２５～３６岁，平均２７岁。术前诊断为原发性不孕９例，继发性不孕２１例。造影前３０ｍｉｎ肌注阿托品０．５ｍｇ，排空...     

用泛影葡胺行子宫输卵管造影对不孕症的应用价值

目的 探讨利用泛影葡胺行子宫输卵管造影对不孕症的诊断价值。方法 对139例不孕症，用76％泛影葡胺采用球囊导管并加压注射法作子宫输卵管造影检查。并在透视下实时点片。结果 139例病人造影全部成功（100％），双侧输卵管显示117例（84．17％），单侧显示13例。发现子宫畸形7例；子宫腔轮廓异常5例；输卵管异常103例，其中输卵管积水23例，输卵管狭窄14例，输卵管不通（阻塞）21例；造影剂盆腔内弥散异常87例。结论 利用球囊导管以及加压注射水溶性造影剂，可以明显提高子宫输卵管造影质量及输卵管再通效果，有重要的临床价值。     

HSG碘油与泛影葡胺影像诊断质量对比研究

目的 探讨碘化油及泛影葡胺两种造影剂行子宫输卵管造影（hysterosalpingography,HSG）对不孕症的影像诊断质量.方法 随机抽取我院自2012年1～8月使用碘化油和泛影葡胺行子宫输卵管造影的患者各200例,统计分析两种造影剂的影像诊断质量.结果 两种造影剂在宫腔、输卵管、盆腔弥散及逆流显示方面具有显著性差异（P〈0.01）,在输卵管积液显示方面具有统计学意义（P〈0.05）.结论 碘化油影像质量高于泛影葡胺,碘油应作为子宫输卵管造影首选造影剂.     

离子型与非离子型造影剂在子宫输卵管造影检查中的应用对照

目的探讨离子型造影剂(泛影葡胺)和非离子型造影剂(碘海醇)在子宫输卵管造影检查中的应用效果。方法对我院2009年6月～2010年5月拟行子宫输卵管造影的180例病人随机选择使用两种不同造影剂检查,对造影过程、造影剂反应情况、影像质量进行对比分析。结果 (1)碘海醇组不良反应发生率低于泛影葡胺组;(2)碘海醇组造影剂所得图像优良率高于泛影葡胺组;(3)两种造影剂逆流现象发生率无显著差异。结论非离子型造影剂可降低不良反应的发生率,在一定程度上提高了子宫输卵管造影图像显示的优良率。     

浅谈碘化油及60％泛影葡胺在子宫输卵管造影中的应用及利弊

目的探讨碘化油与60％泛影葡胺在子宫输卵管造影中的利弊。方法对160例不孕患者分成两组，分别用碘化油及60％泛影葡胺造影，比较两组在造影中的显影情况及不良反应。结果两组不孕患者分别采用碘化油及60％泛影葡胺造影，结果证明60％泛影葡胺优于碘化油。结论60％泛影葡胺在子宫输卵管造影时较安全，并发症较碘化油少，值得临床使用。     

碘化油及泛影葡胺在子宫输卵管造影检查中的应用评价

子宫输卵管造影术为不孕症患者首选的检查方法。我科自60年代到2004年，采用碘化油进行了宫输卵管造影检查。自2004年数字胃肠机投入使用以来，子宫输卵管造影对比剂被复方泛影葡胺所取代，随机抽取碘化油和复方泛影葡胺行子宫输卵管造影术各150例进行对比分析。     

泛影葡胺用于输卵管吻合术后造影分析

泛影葡胺用于输卵管吻合术后造影分析李尊民，张新华，宋文，朱景润（临沂地区人民医院）（临沂地区中医医院）关键词泛影葡胺；造影术；输卵管吻合术于１９８９年２月至１９９３年４月，我院对输卵管吻合术后子宫输卵管造影３７例。现报告如下。１一般资料３７例病人均有...     

数字胃肠机及泛影葡胺在子宫输卵管造影中的应用

目的 本文探讨分析了泛影葡胺对子宫输卵管造影的作用及数字胃肠机在子宫输卵管造影中的应用.方法 应用数字胃肠X线机进行子宫输卵管造影.结果 回顾性分析352例不孕患者子宫输卵管造影表现,原发性不孕的有76例,占21.6%;继发性不孕276例,占78.4%;发现子宫先天性发育不全10例、子宫肌瘤4例、宫腔炎症粘连211例、输卵管结核1例等.结论 在数字胃肠机下使用泛影葡胺行子宫输卵管造影更方便、快速、安全.     

复方泛影葡胺在子宫输卵管造影中的应用价值

目的 总结复方泛影葡胺对子宫输卵管造影的价值。方法 应用60%～70%复方泛影葡胺8～10毫升加温后经通液器注入宫腔,在透视下观查显影满意后摄片,之后取出通液器,嘱咐患者在台上翻身4～5次后再摄第二片。结果 50例复方泛影葡胺子宫输卵管造影均显影满意。结论 复方泛葡胺子宫输卵管造影有一定的临床价值,与传统的碘化油造影剂相比有明显的优越性。     

泛影葡胺与欧乃派克在不孕症子宫输卵管造影检查中的应用价值

目的:对比泛影葡胺和欧乃派克在子宫输卵管检查中的优缺点,探讨泛影葡胺和欧乃派克在不孕症子宫输卵管造影(HSG)检查中的推广应用价值。方法:随机选取欲行子宫输卵管造影的患者,分别用76%泛影葡胺(对照组)及300 mg/ml欧乃派克(研究组)行子宫输卵管造影各150例,术中、术后进行观察与随访,对泛影葡胺与欧乃派克在HSG中的造影效果与安全性进行对比分析。结果:研究组的造影图像优良率为96.7%,对照组优良率为83.3%,两组组间对比差异有统计学意义(P<0.05)。研究组的造影腹痛、恶心、呕吐、头晕等不良反应总体发生率明显低于对照组,对比差异有统计学意义(P<0.05)。结论:不孕症子宫输卵管造影检查选用欧乃派克造影剂可降低不良反应的发生率,提高了子宫输卵管造影图像质量,应优先选用,有推广使用价值。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.