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Heikki Teräväinen 《Acta neurologica Scandinavica》1984,69(2):125-127
Non-selective adrenergic beta-blocking drugs prevented isoproterenol enhancement of essential tremor amplitude far more effectively than beta-1-selective blockers. 相似文献
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Kathleen E. Norman PhD PT Shauna N. D'Amboise MSc PT Giovanna Pari MD Martin E. Héroux PhD PT 《Movement disorders》2011,26(11):2088-2094
Essential tremor is the most common movement disorder, typically characterized by the presence of both postural and kinetic tremor of the hand. In recent studies, we described the effects of altering force and load conditions on tremor amplitude and power in people with essential tremor. In the same participants, we also measured tremor‐related functional disability. In this article we report on the current study on correlations of measures of tremor severity with those of tremor‐related functional disability. Twenty‐one participants with essential tremor had tremor measured in their more tremorous hand. Power spectral and amplitude measures of tremor were calculated for each of 16 conditions: force tremor at 4 submaximal force levels, postural tremor in unloaded and 3 submaximal load conditions, and kinetic tremor in unloaded and 3 submaximal load conditions for each of concentric and eccentric contractions of the wrist extensors. Participants were rated on the hand items of the Fahn‐Tolosa‐Marin rating scale and timed on the unilateral hand tasks of the Test Évaluant la Performance des Membres supérieurs des Personnes Âgées. The most consistently high and significant correlations were found between kinetic tremor measures and the hand task scores and tremor‐B scores (r = 0.548–0.780, P < .01). Postural tremor measures correlated with disability measures only in loaded conditions, most consistently with the hand task measures (r = 0.640–0.725, P < .01). Thus, measures of kinetic tremor and loaded postural tremor, but not unloaded postural tremor or force tremor, relate well to disability captured with dynamic tasks. © 2011 Movement Disorder Society 相似文献
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Jiaxin Peng Ling Wang Nannan Li Junying Li Liren Duan Rong Peng 《Acta neurologica Scandinavica》2020,142(1):74-82
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Roopa Rajan;Reghu Anandapadmanabhan;Aayushi Vishnoi;Anna Latorre;Nivethida Thirugnanasambandam;Alish Dipani;Deblina Biswas;Divya M. Radhakrishnan;Achal Srivastava;Kailash P. Bhatia; 《Movement Disorders Clinical Practice》2024,11(2):136-142
The merits of classifying the heterogeneous group of essential tremors into essential tremor (ET) and essential tremor plus (ETP) are debated. 相似文献
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Most patients with essential tremor experience a transient improvement after ingesting a small amount of alcohol. It has been accordingly suggested that essential tremor patients may have an increased risk of developing alcoholism. In this study, the frequency and amount of alcohol intake of essential tremor patients were found to be largely similar to the drinking habits of a control sample from the general population. This indicates that essential tremor does not generally augment alcohol consumption, nor is it a common cause of alcoholism. 相似文献
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Stefanie H. Müller BSc Emeline Mundwiller BS May Bungeroth Dipl.‐Biol Alexandra Durr MD PhD Manuela Pendziwiat Dipl.‐Biochem Mathieu Anheim MD Susanne A. Schneider Lukas Tittmann Dipl.‐Bibl Stephan Klebe MD Delia Lorenz MD Günther Deuschl MD Gregor Kuhlenbäumer MD PhD 《Movement disorders》2015,30(5):721-724
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Rodger J. Elble 《JOURNAL OF CLINICAL NEUROLOGY》2022,18(2):127
Essential tremor (ET) plus is a new tremor classification that was introduced in 2018 by a task force of the International Parkinson and Movement Disorder Society. Patients with ET plus meet the criteria for ET but have one or more additional systemic or neurologic signs of uncertain significance or relevance to tremor (“soft signs”). Soft signs are not sufficient to diagnose another tremor syndrome or movement disorder, and soft signs in ET plus are known to have poor interrater reliability and low diagnostic sensitivity and specificity. Therefore, the clinical significance of ET plus must be interpreted probabilistically when judging whether a patient is more likely to have ET or a combined tremor syndrome, such as dystonic tremor. Such a probabilistic interpretation is possible with Bayesian analysis. This review presents a Bayesian analysis of ET plus in patients suspected of having ET versus a dystonic tremor syndrome, which is the most common differential diagnosis in patients referred for ET. Bayesian analysis of soft signs provides an estimate of the probability that a patient with possible ET is more likely to have an alternative diagnosis. ET plus is a distinct tremor classification and should not be viewed as a subtype of ET. ET plus covers a more-comprehensive phenotyping of people with possible ET, and the clinical interpretation of ET plus is enhanced with Bayesian analysis of associated soft signs. 相似文献
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Julie Leegwater-Kim Elan D Louis Seth L Pullman Alicia G Floyd Sarah Borden Carol B Moskowitz Lawrence S Honig 《Movement disorders》2006,21(11):2001-2005
Patients with essential tremor (ET) have kinetic arm tremor; this tremor can also have an intentional component. We are unaware of reports of intention tremor of the head in ET. Our aims were to describe, provide electrophysiological data and video documentation of, and estimate the prevalence of intention tremor of the head in our sample. Ten (9.0%; 95% confidence interval = 4.7%-14.3%) of 111 patients had intention tremor of the head; in 7 it involved the neck and in 3 the chin. These patients trended toward having more severe kinetic arm tremor and they had more severe intention tremor of the arms. These observations provide further support for the evolving view that the cerebellum may be involved in ET. 相似文献
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目的 探讨震颤分析在帕金森病(parkinson's disease,PD)和原发性震颤(essential trem-or,ET)鉴别诊断中的应用价值.方法 选取2017年9月至2020年11月在福建省立金山医院门诊和住院确诊的PD患者27例(PD组)和ET患者23例(ET组),所有患者均至少有一侧上肢静止性或姿势性... 相似文献
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Ioannis U. Isaias MD Giorgio Marotta MD Shigeki Hirano MD PhD Margherita Canesi MD Riccardo Benti MD Andrea Righini MD Chengke Tang MD Roberto Cilia MD Gianni Pezzoli MD David Eidelberg MD Angelo Antonini MD PhD 《Movement disorders》2010,25(6):679-686
To investigate over time changes in striatal dopamine transporter (DAT), we performed two sequential N‐ω‐fluoropropyl‐2β‐carbomethoxy‐3β‐(4‐iodophenyl) tropane single photon computed tomography (SPECT) scans in 20 subjects with essential tremor (ET), in 13 with Parkinson disease (PD) and in 23 healthy controls (HC, one scan only). We also performed an [99mTc]ethyl cysteinate dimer bicisate SPECT exam for regional brain network analysis in 9 ET, in a second group of 18 PD (9 with tremor, tPD and 9 akinetic‐rigid dominant, arPD) and in 8 HC. PD subjects had a reduced DAT binding in comparison to ET and HC with an annual decline rate of 7.3% in the contralateral putamen. There were no mean uptake differences between ET and HC at baseline and no uptake loss over time in ET. A discriminant analysis grouped 30% (first scan) and 5% (second scan) of ET as PD and a partition analysis showed overlap between ET and PD for caudate nucleus uptake. Spatial covariance analysis revealed that the expression of the PD‐related regional pattern separated both tPD and arPD from ET and HC. In conclusion, PD and ET do not share a common pattern of dopaminergic loss over time. However, mild impairment of dopamine transporter in the caudate nucleus may contribute to tremor onset in ET. © 2010 Movement Disorder Society 相似文献
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Sarah Schiebler MD Alexander Schmidt MD Simone Zittel MD Tobias Bäumer MD Christian Gerloff MD Christine Klein MD Alexander Münchau MD 《Movement disorders》2011,26(10):1789-1792
The classification of arm tremor in cervical dystonia is a controversial issue. There have been many, at times passionate disputes in the movement disorder community about whether it should be classified as a manifestation of dystonia or essential tremor associated with dystonia. There are arguments in favor of both views. Settling the issue might be relevant to the understanding of the etiological, presumably genetic, background because phenomenological grouping is the starting point for genetic analyses. From this point of view, we outline this tremor debate and add some new clinical data. © 2011 Movement Disorder Society 相似文献
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《Movement Disorders Clinical Practice》2017,4(6):838-842
Introduction
Depression and neuropsychiatric disorders in individuals with essential tremor (ET ) are not well characterized in the literature.Methods
We compared 104 ET subjects with 481 non‐ET controls involved in the Arizona Study of Aging and Neurodegenerative Disorders. An analysis of baseline depression scales and neuropsychiatric inventory (NPI ) was done between the two groups. Additionally, comparisons were made within the ET group based on tremor severity, duration of tremor, and age of onset.Results
There were no significant differences between the ET and non‐ET groups. There were no significant differences in the ET group above and below the median tremor duration. Additionally, no differences were found in the ET group based on objective measures of tremor severity, age of onset, or those with subjectively distressing tremor compared with those without.Conclusion
There were no significant differences in depressive symptoms between ET and non‐ET groups. Furthermore, no correlation was found between depressive symptoms in ET groups based on tremor severity, duration, or age of onset.20.
目的 探讨特发性震颤(EI)的临床和电生理学特点.方法 回顾性分析并比较33例ET患者(ET组)和30例生理性震颤患者(对照组)的震颤类型、程度、幅度和负重对其的影响,以总结ET的临床和电生理学特点.结果 ET组患者动作性震颤(KT)的震颤程度明显高于对照组,震颤幅度明显大于对照组(均P＜0.01);而姿势性震颤(PT... 相似文献