共查询到20条相似文献,搜索用时 46 毫秒
1.
2.
3.
4.
5.
Current Aspects of Modes of Action of Dapsone 总被引:1,自引:0,他引:1
6.
7.
8.
9.
10.
11.
The structure of the skin and the pattern of alteration in chronic ulcerations associated with deficiency of prolidase have been studied superficially in the past. We examined histologically several biopsies taken from apparently normal skin and from ulcerations afflicting a young woman with such a syndrome. Deposits of amyloid were found within the walls of medium-sized vessels and occasionally occluding their lumens. Impaired cutaneous microcirculation resulting from statis, moderate vasculitis, and abnormal structure of the dermis may be responsible for the regional preponderance of deposits of amyloid and ulcerations in the legs. 相似文献
12.
13.
14.
15.
红皮病120例病因分析 总被引:10,自引:1,他引:9
目的:探讨红皮病的病因及并发感染的情况。方法:回顾性分析120例红皮病患者的临床资料。结果:120例患者中73.3%红皮病继发于原有皮肤病,其他致病原因依次为药物过敏、肿瘤,部分原因不明。28.3%并发感染的红皮病患者中,41~60岁组和〉60岁年龄组的感染率高于≤40岁年龄组,差异有统计学意义(P均〈0.05);血浆白蛋白降低组患者感染率高于血浆白蛋白正常组患者,差异亦有统计学意义(P〈0.01)。结论:红皮病病因多种多样,不能忽视非常见病因的存在。随着年龄的增长和血浆白蛋白的降低,红皮病患者的感染率增加,应注意皮肤护理及早期支持治疗。 相似文献
16.
S. Gandini J.‐F. Dor P. Autier R. Greinert M. Boniol 《Journal of the European Academy of Dermatology and Venereology》2019,33(Z2):57-62
The International Agency for Research on Cancer classified, in July 2009, exposure to artificial tanning devices (sunbeds) as carcinogenic to humans. This classification was based on evidence from epidemiological and experimental animal studies. The present chapter will review these epidemiological evidences. The summary risk estimates from 27 epidemiological studies obtained through a meta‐analysis showed an increased risk of melanoma: summary relative risk (SRR) = 1.20 [95% confidence interval (CI) 1.08–1.34]. The risk was higher when exposure took place at younger age (SRR = 1.59; 95% CI 1.36–1.85). The risk was independent of skin sensitivity or population and a dose response was evident. A meta‐analysis of 12 studies was conducted for non‐melanoma skin cancers and showed a significantly increased risk for basal cell carcinoma (SRR = 1.29; 95% CI 1.08–1.53) and for squamous cell carcinoma (SRR = 1.67; 95% CI 1.29–2.17). As for melanoma, the risk for other skin cancers increased for first exposures at young age. Epidemiological studies have gradually strengthened the evidence for a causal relationship between indoor tanning and skin cancer and they fit with prior knowledge on relationship between UV exposure and skin cancer. Additionally, several case–control studies provided consistent evidence of a positive association between use of sunbed and ocular melanoma, also with greater risk for first exposures at younger age. Preventive measures based on information on risk or by requiring parental authorization for young users proved to be inefficient in several studies. The significant impact of strong actions or total ban, such as performed in Iceland, or a total ban of sunbed use, as in Brazil or Australian states, needs to be further assessed. 相似文献
17.
18.
Seven patients with latent syphilis are described, in whom the routine serologic tests (RST) were negative during the first examination and over the course of therapy, and the specific tests (T. pallidum immobilization and immunofluorescence) were repeatedly positive before therapy. Early latent seropositive recurrent forms of syphilis were detected in the majority of these patients' sexual partners. The patients were not administered antisyphilis therapy before. The diagnosis of latent seronegative early syphilis negative in the RST is epidemiologically significant, for it helps timely carry out the necessary treatment and prophylaxis measures to prevent the disease dissemination. 相似文献
19.