慢性前列腺炎患者前列腺液培养及临床意义

目的 探讨慢性前列腺炎患者前列腺液培养及临床意义。方法 选择2001年1月至2002年12月临床诊断慢性前列腺炎,前列腺液白细胞数超过10个,HP的患者280例,其中198例做前列腺液普培药敏实验,淋菌及非淋菌病后前列腺炎82例,同时做前列腺液特殊培养及药敏实验。结果 普通细菌培养198例,无细菌生长72例占36．3％,有细菌生长126例占63．7％,其中球菌类细菌87例,占阳性病例的69％,杆菌类细菌39例,占阳性病例的31％。特殊培养82例,无病原体生长20例占24．4％,有病原体生长62例占75．6％,其中淋病奈瑟菌25例,占阳性病例的40％,支原体衣原体37例,占阳性病例的60％。做20种抗生素药敏试验,耐药率较高。结论 慢性前列腺炎患者做前列腺液培养及药敏试验对于前列腺炎的临床分型及指导治疗有重要意义。     

Treatment of chronic postsurgical osteomyelitis with ciprofloxacin

Sixteen patients (11F, 5M, age 18–83, mean 59.8 years) with chronic postsurgical osteomyelitis were treated with ciprofloxacin. The dosage was 500 or 750 mg twice daily orally during one to six months; four patients started with 300 mg twice daily intravenously and changed after 3–7 days to oral therapy. Twelve patients had implanted prostheses. The organisms involved wereEnterobacteriaceae (11),Pseudomonas aeruginosa (7),Staphylococcus aureus (5),Streptococcus faecalis (4) andBacteroides fragilis (1). Nine patients had pure cultures, seven mixed cultures.

Cure (disappearance of infection symptoms, return of normal function with negative cultures, without resurgery) was obtained in 11 patients, improvement (resurgery required to obtain complete cure) in two. Three patients with infections byStaphylococcus aureus (2) andPseudomonas aeruginosa (1) failed to respond after one and four months treatment respectively. No side effects were observed.

     

Comparative analysis of azithromycin and ciprofloxacin in the treatment of chronic prostatitis caused by Chlamydia trachomatis

A total of 89 patients, (>18 years), with symptoms of chronic prostatitis and inflammatory findings as well as the presence of Chlamydia trachomatis confirmed by DNA/RNA DIGENE hybridization method and/or by isolation, McCoy culture and Lugol stain in expressed prostatic secretion or in voided bladder urine collected immediately after prostatic massage, were examined. The patients were randomized to receive a total of 4.5 g of azithromycin for 3 weeks, given as a 3-day therapy of 1 x 500 mg weekly or ciprofloxacin 500 mg b.i.d. for 20 days. Patients' sexual partners were treated at the same time. Clinical and bacteriological efficacy were evaluated 4-6 weeks after the end of therapy. Significantly higher eradication (36/45: 17/44; P=0.0002) and a significantly higher clinical cure (31/45: 15/44; P=0.0021) were achieved in the group of patients treated with azithromycin than in the ciprofloxacin group.     

Ciprofloxacin in the treatment of chronic bacterial prostatitis: a prospective, non-comparative multicentre clinical trial with long-term follow-up. The German Prostatitis Study Group

The efficacy and safety of ciprofloxacin 500 mg bd for 28 days were assessed in 65 adult males with symptomatic bacterial prostatitis, from eight centres in Germany. Urine and prostatic secretions were obtained for culture. Clinical signs and symptoms were evaluated at 12-18 days during treatment, end of treatment (4-9 days post-treatment), and 1, 3, 6 and 9 months post-treatment. Safety was monitored during and at the end of treatment. E. coli was the most frequent pathogen causing infection (35/62) and Enterococcus faecalis the second most frequent (13/62). The combined bacteriological response by patient determined at return visits 4-9 days post and 1 month post-treatment, respectively, was eradication 48/54 (88.9%), persistence 3/54 (5.6%), eradication with recurrence 1/54 (1.9%) and eradication with reinfection 2/54 (3.7%). The clinical response at 1 month post-treatment was resolution 53/54 (98. 1%) and 1/54 (1.9%) failure. The rates for continued eradication in the extended follow-up were 32/39 (82.1%) after 3 months, 26/34 (76. 4%) after 6 months and 13/22 (59.1%) after 9 months. Nineteen patients experienced at least one adverse event. In two patients the trial was prematurely discontinued due to adverse events.     

Synergistic effect between lycopene and ciprofloxacin on a chronic bacterial prostatitis rat model

Traditionally, long-term antibiotic therapy has been the gold standard treatment for chronic bacterial prostatitis (CBP). However, the treatment outcome is not ideal and long-term administration of antibiotics can result in adverse effects and bacterial resistance. For these reasons, both patients and physicians are dissatisfied with the management of this disease and there is interest in phytotherapy and other alternative therapies. Lycopene, an extract of tomatoes, has been reported to have an anti-inflammatory effect via an antioxidative function. To evaluate the therapeutic effect of lycopene on CBP, we developed a CBP rat model treated with ciprofloxacin or lycopene, or both. After 2 weeks of treatment, results of microbiological cultures of the prostate and urine as well as histological findings of the prostate were analysed. The ciprofloxacin group and the lycopene/ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the control group. The lycopene/ciprofloxacin group also showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group. These results suggest that lycopene may have an additional (synergistic) effect with ciprofloxacin in the treatment of CBP.     

特拉唑嗪联合前列安栓治疗Ⅲ型前列腺炎的疗效

目的探讨α肾上腺素能受体(α-AR)阻滞剂特拉唑嗪联合前列安栓治疗Ⅲ型前列腺炎(CP/CPPS)的疗效和安全性。方法选择Ⅲ型前列腺炎患者146例,采用临床对照随机分为Ⅰ、Ⅱ、Ⅲ组。Ⅰ组(特拉唑嗪组)45例,Ⅱ组(前列安栓组)44例,Ⅲ组(特拉唑嗪联合前列安栓组)57例,每组患者均接受药物治疗4周。采用美国国立卫生研究院慢性前列腺炎症状评分(NIH-CPSI)为主要指标、前列腺液常规中白细胞计数、卵磷脂小体数量为次要指标作为疗效评估,分别评价每组患者的疗效及药物不良反应。结果 135例患者完成4周治疗并接受最终评估,其中Ⅰ组42例,Ⅱ组44例,Ⅲ组49例。三组患者治疗前、后症状评分比较,差异有统计学意义(P<0.05)。药物不良反应包括:①体位性低血压(Ⅰ组11.36%,Ⅲ组14.28%);②肛周不适、腹泻(Ⅱ组10.86%,Ⅲ组12.5%)。因药物不良反应退出治疗的共11例,其中Ⅰ组6.81%,Ⅱ组0%,Ⅲ组14.28%。结论特拉唑嗪、前列安栓均能有效缓解CP/CPPS患者的症状,两者联合用药治疗的疗效优于单药治疗。     

前列安栓治疗119名慢性前列腺炎病人的有效性(英文)

目的:进一步评估前列安栓治疗慢性前列腺炎的有效性和安全性。方法:对复旦大学附属华山医院2001年7月至2002年3月间对期间诊断为慢性前列腺炎的119例患者进行前列安栓治疗。以前列腺按摩液和NIH前列腺炎症状评分表作为评估手段,对每个患者随访一个月后观察治疗效果。结果:经过一个月的治疗随访,总有效率为65.5％。治疗前119人的EPS中白细胞平均为21±20,治疗后为平均12±13。119人的症状程度评分由治疗前的平均12±4下降为7±5;其中疼痛评分由8±3下降为5±3;排尿评分由3.9±2.7下降为2.3±2.3,以上各项指标治疗前后变化情况经配对T检验,P均<0.05。只有两名(1.7％)患者出现了较为严重的腹泻。结论:前列安栓治疗慢性前列腺炎安全、有效,病程较短、炎症程度较轻、症状轻到中度、无既往治疗史的患者疗效尤为显著。     

腺按摩联合α1受体阻滞剂治疗Ⅲ型前列腺炎的疗效观察

目的 评价前列腺按摩联合α1受体阻滞剂治疗Ⅲ型前列腺炎的疗效.方法 将符合Ⅲ型前列腺炎诊断标准的86例患者随机分为治疗组及对照组,治疗组45例,给以每周2次的前列腺按摩及特拉唑嗪2 mg,每天1次.对照组41例仅给以特拉唑嗪2 mg,每天1次.疗程6周.采用美国国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）评分作为疗效评价指标评价两组疗效.结果 86例患者完成了6周的治疗并接受评估,治疗组患者治疗前后NIH-CPSI总分分别为（29.5 ±4.2）、（9.6±3.8）分,对照组治疗前后NIH-CPSI总分分别为（28.9±3.4）、（14.6±3.6）分,两组治疗前后相比总分下降均有统计学意义（t=12.131、6.999,均P＜0.05）,治疗组总分下降幅度明显大于对照组（t=4.649,P＜0.05）.治疗过程中无严重不良反应发生.结论 前列腺按摩联合α1受体阻滞剂治疗能有效缓解Ⅲ型前列腺炎患者的症状,改善患者的生活质量.联合治疗疗效优于单用α1受体阻滞剂治疗.     

Treatment of chronic bacterial prostatitis

The pathogenesis, clinical signs and symptoms, diagnosis and treatment of chronic bacterial prostatitis (CBP) are reviewed. The most common organism associated with CBP is Escherichia coli, although infections with Klebsiella, Enterobacter, Proteus, Pseudomonas, and enterococci have also been documented. The only symptoms of CBP may be those of an acute urinary-tract infection. The use of simultaneous quantitative urine cultures represents the most accurate method for diagnosing CBP. The use of trimethoprim-sulfamethoxazole, the current drug of choice for CBP, is based on results in animals showing good penetration of trimethoprim into acidic prostatic fluid and the knowledge that normal human prostatic fluid is acidic. Studies in patients with CBP, who have alkaline prostatic fluid, have demonstrated poor penetration of trimethoprim into prostatic fluid, which may explain the cure rate of about 40% seen with trimethoprim-sulfamethoxazole. A few patients have been treated successfully with kanamycin and streptomycin, but these drugs must be given by injection. Carbenicillin indanyl sodium has been associated with cure rates of almost 70% in a small number of studies. Both doxycycline and minocycline have been used to treat CBP, but inadequate urine-culture data make these studies difficult to evaluate. Erythromycin produced a cure rate of 88% in one study in patients who received 500 mg (as the stearate salt) four times daily for 14 days. Local injection of antibiotics into the prostate has been reported to be effective in a few cases. Although controlled comparative trials with trimethoprim-sulfamethoxazole are needed, carbenicillin indanyl sodium and erythromycin appear to be the drugs of choice for treating CBP; trimethoprim-sulfamethoxazole should be reserved for patients with CBP unable to tolerate or unresponsive to therapy with these agents.     

前列泰片治疗慢性前列腺炎的效果及对患者免疫功能的影响

目的探讨前列泰片治疗慢性前列腺炎的效果及对患者免疫功能的影响。方法选择2012年3月-2014年3月在本院就诊的90例慢性前列腺炎患者,随机分为观察组和对照组各45例。对照组采用综合治疗加抗生素,观察组在对照组治疗的基础上加用前列泰片治疗,比较两组的临床疗效。结果观察组总有效率为88.89%,高于对照组的71.11%,差异有统计学意义（P〈0.05）。治疗后,观察组前列腺液白细胞数少于对照组,差异有统计学意义（P〈0.01）;观察组患者前列腺液中分泌型免疫球蛋白A（sIgA）的水平低于对照组,差异有统计学意义（P〈0.01）。结论前列泰片治疗慢性前列腺炎效果显著,能明显改善患者前列腺液中的SIgA水平。     

Treatment of chronic osteomyelitis with ciprofloxacin

The results of the treatment of twenty-one patients (age 22–66 years) with chronic bone or joint infections with ciprofloxacin were evaluated. The osteomyelitis was secondary to trauma in 12 patients, joint replacement in six, previous acute hematogenous infection in two and osteotomy in one.Stafylococcus aureus (11 times) andPseudomonas aeruginosa (9 times) were most frequently cultured. The duration of ciprofloxacin therapy averaged 76 days. Concomitant antimicrobial drugs were used in one patient only. Fifteen patients were operated during treatment; in most cases the surgical procedure consisted of a thorough debridement. Nineteen patients could be evaluated. The bacteriological results were as follows: eradication 27; marked reduction 1; eradication with recurrence 1. Contamination occurred in five patients and superinfection in two, without much influence on the final outcome. The investigator's assessment at the end of the therapy was as follows: complete success in 14 patients and partial success in seven. During the follow-up (3–13 months) the therapy was judged completely successful in 16, partially successful in four and unsuccessful in one. Two patients had minor gastric complaints during therapy and one showed a temporary slight increase in the liver transaminases.

     

Intravenous ciprofloxacin versus ceftazidime for treatment of nosocomial pneumonia and urinary tract infection

Intravenous ciprofloxacin and ceftazidime were compared for efficacy in the treatment of nosocomial pneumonia and urinary tract infection (UTI). Patients with nosocomial pneumonia were randomized to receive ciprofloxacin (as the lactate salt) 300 mg i.v. every 12 hours or ceftazidime (with sodium carbonate) 2 g i.v. every eight hours. Patients with UTI were randomized to receive ciprofloxacin 200 mg i.v. every 12 hours or ceftazidime 1 g i.v. every eight hours. Sputum and urine specimens were collected before, during, and after therapy. For patients with pneumonia, the organisms most frequently isolated before treatment began were Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, and Proteus mirabilis. Of the 17 pneumonia patients who completed ciprofloxacin treatment, 15 (88%) had resolution of signs and symptoms or improvement. Of the 15 ceftazidime-treated pneumonia patients, 13 (87%) had resolution or improvement. Staphylococcus aureus, Streptococcus species, Acinetobacter species, and K. pneumoniae infections persisted for the ciprofloxacin treatment failures. Infections by Enterobacter cloacae and Acinetobacter species persisted for the ceftazidime treatment failures. For UTI patients, E. coli was the organism most frequently isolated before treatment. All 14 UTI patients who completed treatment showed resolution or improvement. In the ciprofloxacin group two patients were superinfected by Enterococcus species, and in the ceftazidime group there were two superinfections by Enterococcus species and one by Enterobacter cloacae. Intravenous ciprofloxacin was as effective as ceftazidime in the treatment of nosocomial pneumonia and urinary tract infection. Caution should be exercised when treating serious infections by streptococci or staphylococci.     

生物活性有机锌佐治慢性前列腺炎223例

目的　观察生物活性有机锌辅助治疗慢性前列腺炎的临床疗效。方法　应用补充含生物活性有机锌的活性蛋白制剂 (锌硒宝 )治疗 2 2 3例慢性前列腺炎患者 ,测定治疗前后患者前列腺液中锌离子浓度 ,并观察治疗前后患者的前列腺炎症状评分以及最大尿道闭合压的变化。结果　治疗后 ,前列腺液中锌离子浓度明显提高 ,前列腺炎症状评分和最大尿道闭合压则明显下降 ,其下降幅度均显著大于未补充生物活性有机锌的对照组 (P均 <0 0 5 )。结论　补充生物活性有机锌可提高慢性前列腺炎患者前列腺液中的锌离子浓度 ,有助于患者临床症状的缓解 ,提高其生活质量 ,是慢性前列腺炎有效的辅助治疗方法之一。     

Comparative randomized pilot study of azithromycin and doxycycline efficacy in the treatment of prostate infection caused by Chlamydia trachomatis

The study included 125 adult patients (> 18years of age) who had symptoms of chronic prostatitis and proven presence of Chlamydia trachomatis. The presence of C. trachomatis was confirmed in expressed prostatic secretion or in voided bladder urine collected immediately after prostatic massage by a DNA/RNA hybridization method and/or by isolation on McCoy culture and then by immunofluorescent typing with monoclonal antibodies. The patients were randomized in the ratio 2/1; azithromycin/doxycycline, to receive a total of 4.0 g azithromycin over 4 weeks, given as a single dose of 1 x 1000 mg weekly for 4 weeks or doxycycline 100 mg b.i.d. for 28 days. Patients' sexual partners were treated at the same time. Clinical and bacteriological efficacy was evaluated 4-6 weeks after the end of therapy. In the group of patients with chlamydial infection of the prostate, there was no significant difference between the eradication rates (azithromycin 65/82, doxycycline 33/43; P = 0.82) and the clinical cure rates (azithromycin 56/82, doxycycline 30/43; P = 0.94) of the two antimicrobials.     

宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎的临床疗效

目的宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎的临床疗效。方法选取2018年1月—2019年9月安徽医科大学安庆附属医院收治的62例细菌感染性前列腺炎患者作为研究对象,根据治疗方案的不同将患者分为对照组和观察组,每组31例。对照组患者静脉滴注盐酸左氧氟沙星注射液,0.4 g/d;观察组在对照组基础上口服宁泌泰胶囊,3粒/次,3次/d。两组患者均治疗2周。观察两组患者的临床疗效,同时比较两组治疗前后尿液、前列腺液中白细胞数量和美国国立卫生研究院前列腺炎症状指数(NIH-CPSI)评分。结果治疗后,观察组总有效率为93.54%,显著高于对照组的77.42%,差异具有统计学意义(P<0.05)。治疗后,两组尿液和前列腺液白细胞数量显著下降,差异具有统计学意义(P<0.01);观察组治疗后尿液和前列腺液白细胞数量显著低于对照组,差异具有统计学意义(P<0.01)。两组患者治疗后NIH-CPSI评分均显著下降,差异具有统计学意义(P<0.05);治疗后,观察组NIH-CPSI评分显著低于对照组,差异具有统计学意义(P<0.05)。治疗过程中,观察组恶心呕吐、腹痛腹泻发生例数均显著低于对照组,差异具有统计学意义(P<0.05)。结论宁泌泰胶囊联合左氧氟沙星治疗细菌性前列腺炎具有较好的临床疗效,不良反应发生率较低,值得临床推广。     

普适泰联合盐酸坦洛新缓释片治疗Ⅲaa型前列腺炎临床疗效分析

【摘要】目的探讨普适泰联合盐酸坦洛新缓释片治疗Ⅲaa型前列腺炎的临床疗效。方法将160例Ⅲaa型前列腺炎患者随机分为两组,每组各80例,治疗组给予普适泰1片／次,2次／d口服,盐酸坦洛新缓释片0．2mg,每晚1次口服;疗程6周。对照组仅给予盐酸坦洛新缓释片0．2mg,每晚1次口服;疗程6周。所有患者均于治疗前、治疗结束后行NIH—CPSI评分、前列腺液中WBC计数及药物不良反应评估。结果治疗组患者6周后治愈7例（8．8％）,显效30例（37．5％）,有效34例（42．5％）,无效9例（11．3％）,总有效率为88．8％;对照组患者6周后治愈4例（5．0％）,显效27例（33．8％）,有效24例（30．0％）,无效25例（31．3％）,总有效率为68．8％;治疗组与对照组在治愈率。总有效率两方面比较差异有统计学意义（P〈0．05）。无严重的药物不良反应事件发生。结论普适泰联合盐酸坦洛新缓释片治疗111a型前列腺炎有较满意的临床疗效．且患者耐受件好．     

宁泌泰胶囊联合萘哌地尔治疗慢性非细菌性前列腺炎的临床研究

目的探讨宁泌泰胶囊联合萘哌地尔治疗慢性非细菌性前列腺炎的疗效观察。方法选取2017年5月—2019年5月在河南大学淮河医院泌尿科住院治疗的106例慢性非细菌性前列腺炎患者为研究对象,按照随机数字表法分成对照组和治疗组,每组各有53例。对照组患者口服萘哌地尔分散片,起始剂量为25mg/次,1次/d,1周后未到理想疗效,可增加到50mg/次,1次/d,饭后服用。治疗组在对照组基础上口服宁泌泰胶囊,3~4粒/次,3次/d,饭后服用。两组患者均连续治疗7 d。观察两组的临床疗效,比较两组临床症状的消失时间;同时比较两组最大尿流率、平均尿流率、前列腺液中炎性因子的变化情况。结果治疗后,治疗组总有效率96.23%,显著高于对照组的83.02%(P<0.05)。治疗后,治疗组患者尿频消退时间、尿急消退时间、排尿困难消退时间均显著短于对照组(P<0.05)。治疗后,两组患者最大尿流率、平均尿流率均较治疗前显著提高(P<0.05);且治疗后,治疗组最大尿流率、平均尿流率显著高于对照组(P<0.05)。治疗后,两组患者前列腺液中炎性因子白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)、肿瘤坏死因子α(TNF-α)水平均较治疗前显著降低(P<0.05);治疗后,治疗组前列腺液中炎性因子水平显著对于对照组(P<0.05)。结论宁泌泰胶囊联合萘哌地尔治疗慢性非细菌性前列腺炎具有较好的临床疗效,能有效改善前列腺局部炎症反应,减低局部炎性细胞因子水平,在临床上具有一定的参考价值。     

正清风痛宁片联合美洛昔康治疗骨关节炎的临床研究

目的探讨正清风痛宁联合美洛昔康治疗骨关节炎的临床疗效。方法选取2014年2月—2016年2月隆昌县人民医院收治的骨关节炎患者440例,根据治疗方案的不同分为对照组和治疗组,每组各220例。对照组口服美洛昔康分散片,1片/次,2次/d。治疗组在对照组治疗基础上口服正清风痛宁片,4片/次,3次/d。两组患者均连续治疗4周。观察两组的临床疗效,同时比较两组治疗前后WOMAC评分、肿瘤坏死因子α(TNF-α)、白细胞介素1β(IL-1β)、软骨寡基质蛋白(COMP)及基质金属蛋白酶3(MMP-3)的变化情况。结果治疗后,对照组和治疗组的总有效率分别为89.09%、95.45%,两组比较差异有统计学意义(P0.05)。治疗后,两组患者疼痛评分、关节僵硬评分、日常活动评分、综合评分、IL-1β、TNF-α、COMP、MMP-3均显著降低,同组治疗前后差异有统计学意义(P0.05);且治疗组的降低程度优于对照组,两组比较差异有统计学意义(P0.05)。结论正清风痛宁联合美洛昔康治疗骨关节炎具有较好的临床疗效,可明显改善患者的临床症状,降低血清炎性指标,具有一定的临床推广应用价值。     

前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎的疗效观察

目的探讨前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎的临床疗效。方法选取2014年12月—2015年12月首都医科大学附属北京潞河医院收治的慢性前列腺炎患者86例,随机分为对照组和治疗组,每组各43例。对照组患者口服龙金通淋胶囊,2粒/次,3次/d。治疗组在对照组治疗基础上口服前列舒乐胶囊,4粒/次,3次/d。两组患者均连续治疗4周。观察两组的临床疗效,同时比较治疗前后两组慢性前列腺炎症状指数(NIH-CPSI)评分、前列腺液中的白细胞计数的变化情况。结果治疗后,对照组和治疗组的总有效率分别为79.1%、95.3%,两组总有效率比较差异有统计学意义(P0.05)。治疗后,两组患者生活质量影响评分、排尿症状评分、疼痛评分、总评分、前列腺液白细胞数均显著降低,同组治疗前后差异均具有统计学意义(P0.05);且治疗组的降低程度优于对照组,两组比较差异有统计学意义(P0.05)。结论前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎具有较好的临床疗效,可改善患者的临床症状,降低患者的炎症反应,具有一定的临床推广应用价值。     

中药塌渍联合左氧氟沙星、坦索罗辛治疗慢性前列腺炎的临床疗效分析

目的研究中药塌渍联合左氧氟沙星、坦索罗辛治疗慢性前列腺炎的临床疗效。方法将2018年3月至2020年3月辽宁中医药大学附属第二医院治疗的90例慢性前列腺炎患者,随机分为观察组及对照组,观察组应用中药塌渍联合左氧氟沙星、坦索罗辛治疗,对照组患者应用左氧氟沙星、坦索罗辛治疗,两组患者均治疗4周,比较两组患者慢性前列腺炎症状评分(NIH-CPSI)、国际勃起功能指数(IIEF-5)、焦虑自评量表(SAS)积分、中医症状评分、前列腺液(EPS)中白细胞计数(WBC)以及肿瘤坏死因子(TNF-α)水平情况。结果干预治疗4周,对照组总有效率为71.1%,观察组总有效率为91.1%,观察组疗效明显优于对照组(P<0.05)。治疗后,两组NIH-CPSI评分均较治疗前明显降低(P<0.05),与对照组相比,观察组各项评分均显著降低(P<0.05)。治疗后,两组患者IIEF-5评分均较治疗前增高(P<0.05),与对照组相比,观察组的指数高于对照组(P<0.05)。治疗后,两组患者SAS评分均较治疗前降低(P<0.05);且组间比较,差异有统计学意义(P<0.05)。治疗后,两组中医症状的总积分、主症积分、次症积分较治疗前降低(P<0.05),且观察组总积分和主症积分均低于对照组(P<0.05)。治疗后,两组患者EPS中白细胞计数及TNF-α水平均显著降低(P<0.05),且组间比较差异有统计学意义(P<0.05)。结论中药塌渍联合左氧氟沙星、坦索罗辛治疗慢性前列腺炎临床疗效可靠,值得推广。