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1.
van Schaik JP de Lange EE van Waes PF 《Journal of endourology / Endourological Society》2000,14(9):739-742
PURPOSE: To evaluate a simple method of antegrade ureteral stent insertion allowing optimal positioning of the stent without the use of a retraction string. PATIENTS AND METHODS: Seventeen stents were placed in sixteen patients with ureteral obstruction. Materials included a long vascular introducer sheath and radiopaque markers on the tips of both the sheath and the pusher catheter. For optimal positioning of the proximal pigtail in the renal pelvis, the distal end of the sheath was used to hold a large portion of the pigtail in the extended state prior to its deployment. RESULTS: All stent placements were successful. In one case, the tip of the proximal pigtail was caught in a lower-pole calix. In another case, repeat stent placement was necessary because of recurrent stricture several months after removal of the first stent. All stents functioned properly, as demonstrated by follow-up nephrostography 2 or 3 days after each procedure. CONCLUSION: The insertion method we describe is simple, easy to perform, and fast and avoids the risks associated with the use of a retraction string. 相似文献
2.
Aydin Seref Koksal Ahmet Tarik Eminler Erkan Parlak Ahmet Gurakar 《Transplantation reviews (Orlando, Fla.)》2017,31(3):207-217
Biliary strictures constitute 40% to 60% of the biliary complications after liver transplantation. They are more common after living donor related liver transplantation (LDLT) than orthotopic liver transplantation (OLT). Balloon dilation followed by multiple plastic stent insertion leads to a mean resolution rate of 84% in the treatment of ASs after OLT. Endoscopic treatment of ASs after LDLT is more difficult because of the small size of the ASs, their multiple number and peripheral location. Balloon dilation followed by multiple plastic stent insertion had a mean resolution rate of 53%. Percutaneous transhepatic biliary drainage was required in 16% to 44% of the patients. Refractory cases with complete biliary obstruction and severe stenosis, in whom the stricture could not be traversed with a guidewire, can be treated by magnetic compression anastomosis as a rescue therapy, if the anatomy of the bile ducts is suitable.In this review, we will focus on the endoscopic treatment of ASs, with special emphasis to refractory cases. 相似文献
3.
Purpose
The aim of the study was to evaluate the effectiveness of minimally invasive treatment of ureteral strictures and describe the technique that we used for retrograde placement of ureteral stent in transplant kidneys.Material and methods
We reviewed the medical cards of all transplant kidney patients with persistent ureteral strictures who were managed with periodical ureteral stent placement and balloon dilatation between 2008 and 2016. Different maneuvers that were used to overcome the difficulties for retrograde ureteral stent placement and exchange were discussed. Clinical characteristics and treatment outcomes of the study cohort were analyzed.Results
Between 2008 and 2016, a total of 1026 transplantations were performed in our clinic, and ureteral stricture was found in 13 patients (1.26%). Of the 13 patients, 8 were treated with periodic ureteral stent insertion and balloon dilatation. Ureteral stent insertion or stent exchange was performed in 52 transplant renal units. The overall success rate of retrograde ureteral stent insertion at the first attempt was 75% and stent exchange success rate was 100%. Renal function remained stable in all patients during a median follow-up of 41 months (range, 13–60 months). No other local or systemic complication was encountered and no stent encrustation was noted.Conclusions
Endoscopic management of ureteral stricture by periodical retrograde ureteral stent replacement and balloon dilatation is safe, effective, and highly successful in transplant patients who are not eligible for open reconstructive surgery. 相似文献4.
F. Karakayalı M. Kırnap A. Akdur N. Tutar F. Boyvat G. Moray M. Haberal 《Transplantation proceedings》2013,45(10):3524-3527
ObjectivesAfter liver transplantation, biliary complications are more prevalent in pediatric patients, with reported rates varying between 15% and 30%.MethodsWe retrospectively analyzed biliary complications observed in 84 pediatric liver transplantation patients between July 2006 and September 2012. Biliary reconstruction was accomplished via a duct-to-duct anastomosis in 5 (83.3%) of the 6 patients receiving whole liver grafts and in 44 (56.4%) of the 78 patients who received a segmental live donor graft. For the remaining 34 patients with living donor and 1 patient with whole liver graft, Roux-en-Y hepaticojejunostomy was the preferred method.ResultsPost-transplantation biliary complications were encountered in 26 patients (30.1%). The biliary complication rate was 38% in 49 duct-to-duct anastomosis, whereas it was 20% in the hepaticojejunostomy group consisting of 35 recipients. Thirteen of the 18 biliary leaks were from duct-to-duct anastomoses and the remaining 5 were from the hepaticojejunostomies and 6 of the 8 biliary strictures were observed in recipients with duct-to-duct anastomosis. In 19 of the 26 patients, the biliary complications were successfully treated with interventional radiologic procedures and 1 was treated with stent placement during endoscopic retrograde cholangiopancreatography.ConclusionsPercutaneous interventional procedures are valuable, effective, and life-saving therapeutic alternatives for the treatment of bile leaks and strictures after pediatric liver transplantations. 相似文献
5.
目的 探讨胆道镜下导丝突破法治疗困难胆管吻合口狭窄的安全性并观察临床疗效。方法 回顾性分析2019年1月至2021年9月西安交通大学第一附属医院肝胆外科收治的内镜下逆行性胆胰管造影(ERCP)或经皮经肝胆道引流(PTCD)治疗失败的12例胆管吻合口狭窄病例的临床资料。9例为肝移植术后胆管端端吻合口狭窄,使用经口单人操作胆道镜(SpyGlass)进入胆道;3例为复杂上腹部术后胆管空肠吻合口狭窄,使用经皮经肝胆道镜(PTCS)进入胆道。分析操作成功率、相关并发症及治疗效果。结果 12例病人中,4例针尖样狭窄者均通过胆道镜辅助完成导丝穿越吻合口;余8例为完全狭窄,接受导丝硬头突破法治疗9次(7次SpyGlass胆道镜和2次PTCS),其中6次成功。胆道镜下导丝突破法技术成功率为76.9%(10/13)。导丝通过狭窄后放置PTCD导管(3例)、塑料支架(3例)及全覆膜金属支架(4例)。2例失败者通过PTCD会师及十二指肠内瘘口治疗成功。术后轻度胆管炎2例,保守治疗好转,无出血、穿孔、胆瘘等与导丝突破相关的并发症。术后随访11(3~34)个月,4例已脱支架,无狭窄复发。结论 胆道镜下导丝突破法治疗ERCP或PTCD失败的困难胆管吻合口狭窄安全、可行,近期疗效满意。 相似文献
6.
Background
Long ampullary stenoses and fibrotic distal biliary strictures are not infrequently encountered during endoscopic retrograde cholangiopancreatography (ERCP). Instead of balloon dilation and stenting, we propose that these strictures can be managed with sphincterotome stricturoplasty (SS) during the initial ERCP. 相似文献7.
《Transplantation proceedings》2022,54(2):457-460
BackgroundExternal bile stents may be used to prevent biliary complications. However, the external biliary stent itself has a risk of complications. This study evaluated the frequency and treatment of complications associated with external bile stent.MethodsFrom May 2015 to September 2019, 18 deceased donor liver transplantations (DDLTs) and 25 living donor liver transplantations (LDLTs) were performed. We retrospectively reviewed these patients’ demographic profiles, type of transplantation and presence of biliary complications, external bile stent–related complications, and treatment results.ResultsOverall biliary complications occurred in 12 patients (27.9%): 3 strictures (6.9%), 2 leakages (4.6%), and 7 external bile stent–related complications (16.2%). Among the 7, 4 were self-removal or stent fractures at home, and 2 occurred after removal by a physician. One patient had ileus with peritonitis. Local peritonitis was controlled by antibiotics and fluid therapy, but 1 patient needed an operation because of intestinal obstruction with recurrent local peritonitis. All biliary complications occurred in LDLT, and external biliary stent–related complications also occurred only in LDLT, not in DDLT (P = .014). Interestingly, only 1 of 7 external bile stent–related complications occurred after we adopted the stent buried suture technique on the duodenum (P = .062).ConclusionsExternal bile stent–related complications were higher in LDLT than in DDLT. When performing external bile stent implantation, the stent buried suture technique will help reduce stent-related complications, especially in LDLT. 相似文献
8.
García-Pajares F Sánchez-Antolín G Pelayo SL Gómez de la Cuesta S Herranz Bachiller MT Pérez-Miranda M de La Serna C Vallecillo Sande MA Alcaide N Llames RV Pacheco D Caro-Patón A 《Transplantation proceedings》2010,42(8):2966-2969
Background
Biliary complications, a major source of morbidity after orthotopic liver transplantation (OLT), are increasingly being treated by endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic management has been shown to be superior to percutaneous therapy and surgery. Covered self-expandable metal stents (CSEMSs) may be an alternative to the current endoscopic standard treatment with periodic plastic stent replacement.Objective
To assess the safety and efficacy of temporary CSEMS insertion for biliary complications after OLT.Methods
From November 2001 to December 2009, the 242 OLT performed in 226 patients included 67 cases that developed post-OLT leaks or strictures (29.6%), excluding ischemic biliary complications. CSEMSs were used in 22 patients (33%), 18 male and 4 female, with an overall median age of 55 years (range, 29-69). In-house OLT patients underwent an index ERCP at 26 days (range, 8-784) after OLT. Their records were reviewed to determine ERCP findings, technical success, and clinical outcomes.Results
ERCP with sphincterotomy was performed in all 22 patients, revealing 18 with biliary strictures alone (82%), 3 with strictures and leaks (14%), and 1 with strictures and choledocholithiasis (4%). All strictures were anastomotic. All patients had 1-2 plastic stents inserted across the anastomosis (11 had prior balloon dilation); stones were successfully removed, for an initial technical success rate of 100% (22/22). CSEMSs, were placed at the second ERCP in 14 patients, at the third in 7, and at the fourth in 1. With a median follow-up of 12.5 months (range, 3-25) after CSEMS removal, 21/22 patients (95.5%) remain stricture free and one relapsed, requiring repeat CSEMS insertion. Four patients experienced pain after CSEMS insertion. At CSEMS removal, migration was noted in 5 cases, into either the distal duodenum (n = 4) or the proximal biliary tree (n = 1), and embedding was seen in 1 case. There were no serious complications; no patients needed hepatojejunostomy.Conclusions
ERCP is a safe first-line approach for post-OLT biliary complications. It was highly successful in a population with anastomotic leaks and strictures. The therapeutic role of ERCP to manage biliary complications after OLT in the long term is not well known. In our experience, the high rate (close to 95%) of efficacy and its relative safety allowed us to use CSEMS to manage refractory biliary post-OLT strictures. CSEMS insertion may preclude most post-OLT hepatojejunostomies. 相似文献9.
C. Sanna D. Reggio A. Ricchiuti P. Strignano G. Ciccone 《Transplantation proceedings》2009,41(4):1319-1321
Biliary complications after orthotopic liver transplantation (OLT) still remain a major cause of morbidity and mortality. The most frequent complications are strictures and leakages in OLT cases with duct-to-duct biliary reconstruction (D-D), which can be treated with dilatation or stent placement during endoscopic retrograde cholangiopancreatography (ERCP), although this procedure is burdened with potentially severe complications, such as retroperitoneal perforation, acute pancreatitis, septic cholangitis, bleeding, recurrence of stones, strictures due to healing process. The aim of the study was to analyze the outcome of this treatment and the complications related to the procedure. Among 1634 adult OLTs, we compared postprocedural complications and mortality rates with a group of 5852 nontransplanted patients (n-OLTs) who underwent ERCP. Of 472 (28,8%) post-OLT biliary complications, 319 (67.6%) occurred in D-D biliary anstomosis cases and 94 (29.5%) patients underwent 150 ERCP sessions. Among 49/80 patients (61.2%) who completed the procedure, ERCP treatment was successful. Overall complication rate was 10.7% in OLT and 12.8% in n-OLT (P = NS). Compared with the n-OLT group, post-ERCP bleeding was more frequent in OLT (5.3% vs 1.3%, P = .0001), while the incidence of pancreatitis was lower (4.7% vs 9.6%, P = .04). Procedure-related mortality rate was 0% in OLT and 0.1% in n-OLT (P = NS). ERCP is a safe procedure for post-OLT biliary complications in the presence of a D-D anastomosis. Morbidity and mortality related with this procedure are acceptable and similar to those among nontransplanted population. 相似文献
10.
H ten Hoopen-Neumann M F Gerhards T M van Gulik A Bosma P C Verbeek D J Gouma 《Digestive surgery》1999,16(3):209-213
BACKGROUND: We found a high proportion of patients with implantation metastases during follow-up after resection of a proximal cholangiocarcinoma. A remarkable fact was that all these patients had undergone preoperative endoscopic retrograde cholangiopancreatography (ERCP) with placement of a stent. ERCP is frequently used in the assessment of the proximal extension of Klatskin tumors and is usually followed by stent insertion for biliary drainage. The aim of this study was to analyze the possible risk factors leading to implantation metastases in this series of patients. METHODS: Fifty-two patients who had undergone resection of a Klatskin tumor were divided into 2 groups, comparing patients who had had preoperative ERCP and stent placement (n = 41) and patients without preoperative drainage (n = 11). RESULTS: Eight patients developed implantation metastases within 1 year after resection, all of whom had undergone preoperative stent placement (8/41, 20%). None of the patients without preoperative stenting developed implantation metastases. In 22 patients bile samples were taken during operation. Sixteen (72.7%) patients had malignant cells and 4 (18.2%) patients atypical cells in the bile sample. There was no difference in cytology results between the 2 groups. CONCLUSION: This study suggests that preoperative ERCP with biliary drainage is associated with a higher frequency of implantation metastases after resection of Klatskin tumors. A properly planned prospective study, however, is needed to determine whether bile duct stenting in patients with resectable bile duct tumors is a true risk factor for the development of implantation metastases. 相似文献
11.
背景与目的 随着腔内治疗的发展,累及左锁骨下动脉(LSA)的Stanford B型主动脉夹层的治疗方案逐渐成熟,但由于该部位解剖结构复杂、器具自身局限,仍旧存在内漏、锚定区损伤、逆撕等并发症。本研究通过单中心回顾性研究探讨Castor单分支支架治疗Stanford B型主动脉夹层的效果。方法 纳入中国人民解放军海军军医大学附属第一医院血管外科自2018年12月─2021年10月期间使用Castor单分支支架进行腔内手术的Stanford B型主动脉夹层患者。收集入组患者的术前Dicom格式全主动脉计算机体层成像血管造影(CTA)影像、术中详细信息及随访预后结果,使用EndoSize软件测量夹层近远端锚定区动脉直径、病变长度、LSA开口与夹层关系等指标,并结合术中使用移植物情况计算支架放大率,观察并记录手术成功率、近远期并发症率等指标。结果 共纳入107例Stanford B型主动脉夹层患者,全部采用腔内手术方式,手术均取得技术成功。夹层近端主要裂口与LSA距离(42.7±17.3)mm;夹层近端边缘与LSA距离(7.7±13.2)mm;主动脉近端锚定区直径(31.5±3.0)mm;左颈总动脉开口远端与LSA开口近端距离(8.5±2.6)mm。Castor主体支架近端直径(32.5±3.3)mm,远端直径(26.6±3.3)mm,分支支架直径(10.7±3.5)mm。主体支架近端放大率为(3.2±3.5)%,远端放大率为(0.1±9.5)%。围手术期与随访期间,共9例患者死亡,其中1例术前严重低血压,术后1 d死于低灌注引起的多脏器功能衰竭;1例患者于术后4 d死于夹层逆撕破裂;1例患者于术后1个月死于呼吸衰竭;1例患者于术后4个月死于肺部感染;2例患者于术后6个月死于心衰;2例患者分别于术后9个月及14个月死于脑出血;1例患者于术后11个月死于不明原因疾病。6例患者出现主动脉夹层相关不良事件,其中围手术期出现1例夹层逆撕,3例脑梗,随访期间出现1例Ib型内漏,1例分支支架闭塞。结论 Stanford B型主动脉夹层病变往往累及LSA,腔内手术需要将支架锚定在健康的锚定区同时保留LSA,以防止脑梗及截瘫等并发症。Castor单分支支架能够很好地适用于累及LSA的Stanford B型主动脉夹层的腔内治疗,在急性期的治疗上具有一定优势。 相似文献
12.
Klaus Mönkemüller Lucia C. Fry Michael Bellutti Helmut Neumann Peter Malfertheiner 《Surgical endoscopy》2009,23(9):1961-1967
Background
Endoscopic retrograde cholangiopancreatography (ERCP) is technically more challenging in patients with postsurgical anatomy. We assessed the technical success of performing ERCP with the double balloon enteroscope (DBE) in patients with Roux-en-Y anastomosis.Methods
This is a prospective evaluation of patients with Roux-en-Y anastomosis who underwent ERCP with the DBE. Diagnostic success was defined as successful duct cannulation or securing the diagnosis, and therapeutic success was defined as the ability to treat the underlying disorder. Complications of ERCP were defined according to standard criteria.Results
ERCP using the DBE was performed on 17 occasions in 11 patients (10 men; mean age, 59.7 (range, 36–77) years) with Roux-en-Y anastomosis with or without hepaticojejunostomy. Indications for ERCP: biliary obstruction or cholestasis (n = 11). The overall diagnostic success was 82%, and the therapeutic success was 58%. Reasons for failed biliary cannulation included: inability to reach the proximal end of the afferent loop (n = 1), impossibility to advance the wire into the CDB despite adequate insertion of the biliary catheter into the distal CBD (n = 2), and inability to advance the stent over an adequately placed guidewire (n = 1). One major complication occurred (5.8%): perforation of the hepaticojejunostomy in a patient with recurrent choledocolithiasis, which was successfully resolved surgically.Conclusions
ERCP using the DBE is feasible in patients with complex postsurgical anatomy, permitting diagnostic and therapeutic interventions in 82% and 58% of cases, respectively. Nevertheless, due to the complex anatomy, presence of adhesions, and looping of the usually long limbs complications can occur. 相似文献13.
Objective
We evaluated the risk factors for biliary complications and surgical procedures for duct-to-duct reconstructions in adult living donor liver transplantation (LDLT).Patients and Methods
From February 2005 to March 2008, we performed 100 cases of adult LDLT with duct-to-duct biliary reconstruction, using 64 right lobe grafts, 33 left lobe grafts, and 3 right lateral grafts. We employed 4 types of duct-to-duct procedures: all interrupted 6-0 Prolene suture (group 1, n = 9); continuous posterior and interrupted anterior wall 6-0 Prolene suture (group 2, n = 49); all continuous 7-0 Prolene suture (group 3, n = 26); and all continuous 7-0 Prolene suture with external stent (group 4, n = 16). Biliary complications were defined as an anastomosis stricture or a leakage.Results
Thirty-four patients experienced biliary complications during the follow-up period (median, 27 months). The incidence of stricture was 27% and that of leakage, 8%. There were no perioperative, intraoperative, or anatomic risk factors for biliary complications, except the type of duct-to-duct procedure. Group 1 and 2 patients showed higher incidences of biliary strictures than groups 3 and 4 (43.1% vs 4.7%; P = .00). Group 3 patients experienced a higher incidence of bile leakage than the other groups (23.1% vs 2.7%; P = .004).Conclusions
The type of biliary reconstruction is a factor affecting biliary complications following duct-to-duct anastomosis in LDLT. Duct-to-duct biliary anastomosis with 7-0 monofilament suture and a small external stent is a feasible procedure in LDLT that significantly reduces the incidence of biliary complications. 相似文献14.
Endoscopic treatment of bile duct complications after orthotopic liver transplantation 总被引:1,自引:0,他引:1
Polese L Cillo U Brolese A Boccagni P Neri D Bassi D Erroi F Zanus G D'Amico DF Norberto L 《Transplantation proceedings》2007,39(6):1942-1944
AIM: To assess the indications and results of endoscopic retrograde cholangio-pancreatography (ERCP) in patients who have undergone ortotopic liver transplantation (OLT). METHODS: We reviewed data from 42 consecutive patients who underwent ERCP for biliary complications after OLT over an 8-year period, in particular recording indications and success of the treatment after a mean of 17 months follow-up. RESULTS: Cholangiograms performed in 33/42 patients (79%) displayed anastomotic strictures in 17 patients (52%), bile duct stones in 8 (24%), both bile duct stones and an anastomotic stricture in 2 (6%), papillary stenosis in 1 (3%), and anastomotic biliary leakage in 1 (3%). In contrast, the contrastogram was normal in four patients (12%). Stone extraction was completed in 9/10 patients (90%) with a mean of 1.2 sessions, while stricture dilation was achieved in 12/19 patients (63%) after a mean of 1.7 sessions, by stent positioning (n = 7), balloon dilation (n = 4), or Soehendra dilator (n = 1). Both biliary leakage and papillary stenosis were cured by ERCP. Only one procedure-related complication -- severe pancreatitis (2.4%) -- was observed and no mortality. CONCLUSION: ERCP is a safe and effective mode of management of bile duct complications after OLT. It should be attempted before a surgical approach. Better results are obtained for treatment of biliary stones than of anastomotic strictures. 相似文献
15.
Background and study aims Stent migration occurs in about 5–10% of patients undergoing biliary stenting. The aim of this study was to analyze the risk
factors for stent migration in patients with benign and malignant strictures.
Patients and methods We retrospectively analyzed records of 524 biliary plastic stent placement procedures. Details noted included the cause and
localization of stricture, characteristics and number of stents, direction of stent migration, presentation of patient with
migrated stent, and the methods used for retrieval of migrated stents.
Results Two hundred and four (38.9%) of the procedures were performed for benign biliary strictures (BBS) and 320 (61.1%) for malignant
biliary strictures (MBS). Thirty-four patients had 45 migrated biliary stents. The rate of migration was 8.58% (proximal 4.58%
and distal 4.00%). Migration frequency was higher in BBS compared with MBS (13.7% versus 5.3%, p = 0.001). In BBS, the rate of stent migration was higher in cases with one (19.3%) and two stents (20.9%) when compared with
cases with multiple stents (2.7%) (p = 0.001; p = 0.001, respectively). Migration occurred more frequently (10.9%) in cases with two stents when compared both to cases with
one stent (3.0%) and those with multiple stents (0%) in MBS (p = 0.008; p = 0.020, respectively). In BBS, short stents migrated more frequently proximally (77%) and long stents more frequently distally
(73%) (p = 0.008). In BBS, migration in cases with proximal stricture occurred more frequently distally (76.9%), while in those with
distal stricture, migration was more frequently proximal (73.3%) (p = 0.008). All of the proximally migrated stents could be successfully retrieved endoscopically.
Conclusions The risk of stent migration is higher in BBS compared with in MBS. The cases with multiple stents had significantly lower
stent migration. In BBS, long stent, proximal and postcholecystectomy strictures were associated with distal migration, while
short stent, distal and non-postcholecystectomy strictures were associated with proximal migration. 相似文献
16.
《Transplantation proceedings》2023,55(4):940-944
BackgroundBiliary stricture is a common complication of living donor liver transplantation (LDLT). Endoscopic retrograde biliary drainage (ERBD) is the primary treatment of biliary stricture, which is sometimes refractory. This study aimed to evaluate the risk factors for biliary stricture after LDLT and present successful management for refractory biliary stricture.MethodsData from 26 patients who underwent LDLT were retrospectively analyzed. The relationship between the incidence of biliary strictures and clinical variables, including pre/intra/postoperative factors, was assessed.ResultsUnivariate analysis showed that ABO incompatibility (P = .037) was a significant risk factor for biliary strictures. Case 1 was a 57-year-old woman who underwent LDLT using a left-lobe graft for primary biliary cholangitis (PBC) and developed a biliary stricture 1 month after surgery. Percutaneous transhepatic cholangiodrainage (PTCD) and embolization of the portal vein and hepatic artery were performed. Thereafter, ethanol was injected into the biliary duct, and the intervention was successfully completed. Case 2 was a 54-year-old woman who underwent LDLT using a right-lobe graft and duct-to-duct biliary reconstruction for PBC. Internal plastic stent insertion by ERBD was unsuccessful due to the significantly bending bile duct. After PTCD, the gun-site technique for the posterior branch and dual hepatic vascular embolization of the anterior branch was performed. The patient was followed up without an external fistula tube.ConclusionABO incompatibility was a risk factor for refractory biliary stricture. Appropriate procedures should be chosen based on stricture types. 相似文献
17.
Ertan Emek Ayfer Serin Tolga Sahin Pinar Yazici Yildiray Yuzer Yaman Tokat Birkan Bozkurt 《Transplantation proceedings》2019,51(7):2439-2441
PurposePrimary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown origin. Although the course of PSC is variable, it frequently is progressive, leading to cirrhosis and requiring a liver transplantation (LT) in more than half of the patients. PSC is the fifth most common indication for LT in the United States and one of the leading indications in Scandinavian countries, whereas PSC affects fewer than 5% of patients undergoing LT in Turkey. In this study, we analyzed our results in the patients with LT owing to PSC.Materials and MethodsBetween March 2013 and August 2017, all adult patients (>18 years) with LT owing to PSC were analyzed, and clinical data were obtained via retrospective review of patient charts. Demographic features, presence of any concomitant inflammatory bowel disease (IBD), time to LT, and outcome data were recorded.ResultsThere were 15 patients (8 men and 7 women) with a mean age of 46 ± 13 (age at diagnosis = 36 y). Median time to transplantation was 3 years (range: .5–14 yrs.). All patients had a pretransplant history of IBD. Concomitant cholangiocarcinoma was diagnosed in 1 patient (6.5%). Postoperative complications were observed in 4 patients (26%), and in 2 patients (13%) PSC recurred at a mean of 52 months postorthotopic LT. Disease-free survival and overall survival were 37.3 and 38 ± 21 months, respectively. One of the patients with recurrence and 1 with graft failure owing to rejection died in the follow-up period.ConclusionsIn one single-center study of adults with PSC, we found that all patients with PSC had IBD at diagnosis. The recurrence rate (13%) was comparable to the literature (20% [5.7–59%]). Despite the low frequency of PSC in our clinic, LT in these patients resulted in favorable outcomes regarding postoperative morbidity and mortality compared with other etiologies. 相似文献
18.
The Role of Endoscopic Procedures in the Management of Postcholecystectomy and Posttraumatic Biliary Leak 总被引:10,自引:0,他引:10
Endoscopic retrograde cholangiopancreatography (ERCP) is an important tool in the evaluation of the biliary system. It not
only diagnoses the site of biliary leak following bile duct injury, but it also acts as a therapeutic modality to allow interventional
pro-cedures such as sphincterotomy, nasobiliary drainage, or stent placement to be performed. The present study was carried
out to evaluate the role of endoscopic management of biliary leak, following either liver trauma or cholecystectomy. Of a
total 21 patients with bile leak following liver trauma and biliary surgery, 20 were managed by various endoscopic procedures.
In the postcholecystectomy group, ERCP revealed a cystic duct leak in 9 patients and common bile duct injury in 6 patients.
These complications were managed by sphincterotomy alone in 2 patients, by nasobiliary drainage alone in 4 patients, by sphincterotomy
and nasobiliary drainage in 8 patients, and by sphincterotomy and stent placement in 1 patient. Posttraumatic biliary fistula
was successfully managed by performing sphincterotomy followed by the placement of nasobiliary drainage in all of five patients
who had suffered trauma injury.
Received: August 2, 1999 / Accepted: July 25, 2000 相似文献
19.
De Angelis P Foschia F Romeo E Caldaro T Rea F di Abriola GF Caccamo R Santi MR Torroni F Monti L Dall'Oglio L 《Journal of pediatric surgery》2012,47(5):885-888
Background/purposeManagement of choledochal cysts consists of surgical excision and hepaticojejunal anastomosis. Endoscopic retrograde cholangiopancreatography (ERCP) can be used to resolve complications and to evaluate the biliary tract and pancreatobiliary duct junction. Our aim was to underline the importance of ERCP for optimal management.MethodsFrom 2005 to 2011, 28 patients were reviewed (21 female, 7 male; mean age, 5.71 years; range, 2-16 years). After imaging, all patients underwent elective ERCP and were referred for surgery.ResultsCholedochal cyst was diagnosed at ultrasound and magnetic resonance cholangiopancreatography in all examined patients; common biliopancreatic duct was diagnosed in 3 (20%) of 15 patients at magnetic resonance cholangiopancreatography and in none at ultrasound. Endoscopic retrograde cholangiopancreatography showed choledochal cyst in all patients and common biliopancreatic duct in 19 (68%) of 28 patients. Twelve patients underwent sphincterotomy. All patients underwent surgical extrahepatic biliary tree resection and hepaticojejunal anastomosis. Mean period of hospitalization was 9.5 days (range, 6-13 days). No major complications related to ERCP were observed. Two patients needed postoperative ERCP for complications (pancreatitis during follow-up).ConclusionsIn our pediatric experience, ERCP is feasible and safe. It can rule out other possible biliary tract anomalies and help plan the timing and choice of the appropriate surgical procedure. 相似文献
20.
Hironari Kato Hirofumi Kawamoto Koichiro Tsutsumi Ryo Harada Masakuni Fujii Ken Hirao Naoko Kurihara Osamu Mizuno Etsuji Ishida Tsuneyoshi Ogawa Hirotoshi Fukatsu Kazuhide Yamamoto Takahito Yagi 《Transplant international》2009,22(9):914-921
Biliary strictures after living donor liver transplantation (LDLT) with duct-to-duct (D-D) reconstruction are associated with postoperative morbidity and mortality. The aims of this study were to evaluate the long-term outcomes of endoscopic deployment of plastic stents, and to investigate factors associated with the stent deployment failure. Between April 2001 and May 2007, 96 patients received LDLT with D-D reconstruction at Okayama University Hospital. Among them, 41 patients (43%) had anastomotic biliary strictures, and all were referred first for endoscopic retrograde cholangiography (ERC). When deployment was unsuccessful, a percutaneous transhepatic procedure was employed. Successful stent deployment was achieved in 35 out of total 41 patients (85%) by both procedures. Among the 35 patients, 28 had their stents removed as a result of strictures resolution. Eight patients underwent ERC and repeated stent deployment as a result of recurrence of the strictures. Finally, 21 out of 41 (51%) patients with biliary stricture were completely treated by endoscopic therapy during the observation period (median 873 days: range 77–2060). By multivariate analysis, biliary leakage was associated with stent deployment failure. Endoscopic deployment of plastic stents is a first-line therapy for patients with biliary stricture after LDLT. 相似文献