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目的探讨腹腔镜治疗异位妊娠并出血性休克的有效性、安全性和可行性。方法回顾性分析异位妊娠并出血性休克腹腔镜组67例和开腹组52例的住院时间、手术时间、进腹时间、术中出血量、术后肛门排气时间及并发症等。结果腹腔镜组手术时间为(42.0±7.0)min,与开腹组(45.0±12.0)min相比,差异无统计学意义(P>0.05);腹腔镜组术中出血量平均为(34.0±17.0)ml,与开腹组(42.0±7.0)ml相比,差异有统计学意义(P<0.01);进腹时间腹腔镜组为(1.5±1.0)min,明显短于开腹组(6.5±1.0)min(P<0.01);术后肛门排气时间腹腔镜组为(13.5±4.5)h,短于开腹组(37.5±12.5)h(P<0.01);住院时间腹腔镜组为(4.22±1.20)d,明显短于开腹组(6.74±1.67)d(P<0.01)。两组患者均未发生术中及术后并发症和死亡。结论在有效抗休克及完善的生命体征监护及麻醉管理下,结合熟练的腹腔镜操作技术进行腹腔镜手术治疗异位妊娠并出血性休克是安全、有效和可行的。 相似文献
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郭慧 《糖尿病天地(学术刊)》2021,(6)
目的:研究异位妊娠伴失血性休克孕妇采用腹腔镜手术治疗的临床效果.方法:选取2018年11月-2019年11月期间在本院接受治疗的98例异位妊娠患者作为研究对象,随机分为对照组(49例)和观察组(49例),98例患者均伴有失血性休克,对照组采用开腹手术方案,对观察组予以腹腔镜手术方案.对比两组患者围术期相关指标及并发症情... 相似文献
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目的:探讨自体血回输对异位妊娠术后炎症反应的影响。方法:选择2013-01-2015-08 169例异位妊娠大出血手术患者为研究对象。根据患者是否同意以及是否符合自体血回输适应证,分为自体血回输组93例和异体血输注组76例。记录2组术中失血量、术中回收血量、异体血输入量、输血反应及术后伤口感染发生率。检测术前、术后1d及5dC-反应蛋白(CRP)、红细胞沉降率(ESR)、白细胞介素-6(IL-6)、干扰素-γ(IFN-γ)、肿瘤坏死因子-α(TNF-α)等炎症反应指标。结果:1自体血回输组的异体血输注量、输血反应和术后感染率明显低于异体血输注组(P0.05)。2与术前相比,2组术后CRP和ESR均明显升高(P0.05),自体血回输组升高幅度低于异体血输注组(P0.05);与术前相比,2组术后IL-6明显升高(P0.05),自体血回输组升高幅度高于异体血输注组(P0.05);异体血输注组IFN-γ术后1d明显下降,术后5d恢复至术前水平,自体血回输组术后5d IFN-γ明显升高;2组术后TNF-α浓度与术前比较无明显变化(P0.05)。结论:自体血回输患者比异体血输注患者术后炎症反应轻。 相似文献
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腹腔镜手术与开腹手术治疗异位妊娠疗效对比观察 总被引:2,自引:0,他引:2
目的观察比较腹腔镜手术与开腹手术治疗异位妊娠的临床疗效。方法有生育要求的异位妊娠患者126例,随机分为腹腔镜组和开腹组,各63例,分别接受腹腔镜手术和开腹手术治疗。比较两组术中出血量、手术时间、术后肛门排气时间、平均住院时间以及术后输卵管通畅情况。结果两组均顺利完成手术。腹腔镜组手术时间为(31.2±12.3)min,术中出血量为(42.2±15.6)ml,术后肛门排气时间为(12.5±1.9)h,平均住院时间为(3.5±1.4)d,术后输卵管通畅率为82.5%;开腹组分别为(46.0±12.5)min、(65.5±18.3)ml、(26.8±5.7)h、(6.0±2.1)d和53.9%,两组相比,P均〈0.05。结论腹腔镜手术治疗异位妊娠创伤小、出血少、术后恢复快、住院时间短、输卵管通畅率高,疗效优于开腹手术。 相似文献
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腹腔镜手术治疗异位妊娠143例临床分析 总被引:1,自引:0,他引:1
目的探讨腹腔镜手术治疗异位妊娠的可行性。方法对143例输卵管妊娠患者行腹腔镜下手术,有生育要求者尽可能行保全性手术,无生育要求者行输卵管切除术。结果 143例异位妊娠均成功实施腹腔镜手术,成功率100%。结论腹腔镜手术治疗异位妊娠是首选手术方式。 相似文献
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目的 探讨腹腔镜下异位妊娠治疗的可行性.方法 2008-05~2009-04采用腹腔镜治疗输卵管异位妊娠65例(腹腔镜组),根据病变情况及患者是否要求保留生育功能分别采取输卵管切除术或开窗术.并随机抽2003-08~2005-06我科收治的异位妊娠开腹手术的65例(对照组),对两组五项观察指标进行比较.结果 腹腔镜组65例异位妊娠均在腹腔镜下完成手术,65例均经病理证实,术前诊断符合率为100%.65例中同时合并卵巢囊肿4例,合并盆腔粘连18例,合并不孕症8例.与开腹手术相比,腹腔镜组从手术时间、术中出血量、住院天数、术后恢复自如活动、肛门排气时间等明显优于开腹组(P均<0.01).结论 腹腔镜手术具有安全、微创、快捷等特点,腹腔镜手术治疗异位妊娠的近期和远期效果均优于开腹手术,腹腔镜手术已成为异位妊娠手术治疗的标准方法 之一. 相似文献
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目的 :探讨纳络酮 (naloxone,NAL)对失血致低血容量性休克大鼠的治疗作用。方法 :颈总动脉放血 ,使平均动脉压 (MAP)降至 6 .0 k Pa,稳定 1h,完成失血致血容量性休克大鼠模型 ,2 1只大鼠随机均分为 :休克组、纳络酮治疗组、正常对照组。观察 NAL 治疗前后及各时相点大鼠呼吸频率 (RR)、MAP、血液指标等各参数的变化。结果 :纳络酮组给药后 ,MAP即刻升高 ,5 min后 MAP升至 (13.6± 2 .0 ) k Pa,较休克组增高明显 (P<0 .0 1) ,休克组、纳络酮治疗组失血后 RR明显减慢 ,纳络酮给药后 30 min RR升至高峰 (84± 10 ) / min,与休克组相比明显增加 (P<0 .0 1)。NAL 降低了肺体指数和肺含水率 ;升高 p H,Pa O2 ,降低 Pa CO2 ,改善酸中毒和心肺功能。结论 :纳络酮在失血致低血容量性休克大鼠治疗过程中有重要作用 ,能有效减轻休克的严重程度 相似文献
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目的探讨乳酸钠林格液(RL)联合己酮可可碱(PTX)复苏对重度失血性休克大鼠肺缺血再灌注损伤的保护作用及机制。方法将48只健康雄性SD大鼠随机分为对照组、模型组、RL组及RL+PTX组各12只,后三组均采用改良Wigger′s法制备重度失血性休克模型,模型制备成功后RL组予3倍失血量的RL复苏;RL+FTX组复苏方案同RL组,但复苏液中加入PTX;对照组仅行麻醉。分别于休克前、复苏前及复苏后1、2,4h检测四组呼吸指数(RI);复苏后4h检测肺通透指数、肺湿干质量比(W/D),观察肺组织病理学变化并进行肺损伤评分,测定肺组织中基质金属蛋白酶-2(MMP-2)和IL-8水平。结果与对照组比较,其余三组啼损伤评分、肺W/D、肺通透指数均显著升高,尤以RL组和RL+FIX组为著(P均〈0.05);与RL组比较,RL/PTX组RI、肺通透指数、肺W/D显著降低,肺组织病理学变化显著减轻,肺损伤评分显著减少,肺组织MMP-2、IL-8水平显著降低(P均〈O.05)。结论 RL联合FTX复苏可显著减轻重度失血性休克大鼠肺缺血再灌注损伤,可能机制为抑制肺组织内IL-8和MMP-2生成而减轻炎性反应。 相似文献
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Acute hemorrhage is a major cause of death in both civilian and military trauma. The suboptimal effect of the volume of standard crystalloids that can be infused during transport has resulted in a need for a more efficacious fluid for the prehospital management of both civilian and military trauma. Markedly hypertonic sodium chloride solutions have been shown to improve transiently the hemodynamic consequences of shock in animal models. The use of small volumes of 7.5% NaCl in 6% dextran 70 has resulted in a solution superior to equal volumes of standard crystalloids in the ability to resuscitate animals from hemorrhagic shock. The hypertonic sodium chloride/dextran solution has the potential advantages of improving survival, producing a beneficial hemodynamic effect with smaller fluid volumes, reducing total fluid requirements during resuscitation, and being stored easily. This solution may prove valuable in the early resuscitation of the hypovolemic trauma patient and merits further clinical trials. 相似文献
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目的:观察分析重度失血性休克后凝血机制的变化及其处理。方法:重度失血性休克患者17例,给予生命体征监测,观察其全身及手术伤口局部出血情况,定时抽取血样做血常规、肝肾功能及凝血功能测定,对符合凝血功能障碍诊断标准者均给予输血及补充凝血因子、止血及积极治疗原发病等处理。结果:所有患者均在休克后发生全身多处出血或渗血;血红蛋白显著低于正常值,血小板明显减少;转氨酶异常升高;凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)时间延长,国际标准化比值(INR)显著高于正常值,凝血酶原活动度(AT)显著低于正常值(与正常值比较,均P<0.01)。所有患者经过治疗后,出血现象均得到控制,凝血机制相关指标均恢复正常或接近正常范围(与治疗前比较,均P<0.05或P<0.01),同时转氨酶也有显著下降(与治疗前比较,均P<0.01)。结论:重度失血性休克后均可能发生凝血功能障碍,经及时给予输血、补充凝血因子、止血及原发病治疗后,均可得到有效的控制。 相似文献
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Ectopic pregnancy is the most common cause of maternal mortality in the first trimester of pregnancy. The aim of this study was to find risk factors and clinical characteristics associated with ruptured ectopic pregnancies at a medical center in eastern Taiwan in a 19-year period. This was a retrospective observational study that included patients diagnosed with ectopic pregnancy between August 1999 and December 2018. Data about the demographic variables, initial presentation, pre-treatment beta-human chorionic gonadotropin levels, treatment routes (laparoscopy or laparotomy), surgical methods (salpingostomy or salpingectomy), operation time, blood loss amount, the status of ectopic pregnancy (ruptured or unruptured), the requirement for transfusion, and duration of hospital stay were collected. The categorical and continuous variables were analyzed using the correlation coefficients. This study included 225 women who were diagnosed as having an ectopic pregnancy. There were 49 and 176 women with unruptured and ruptured ectopic pregnancies, respectively. The beta-human chorionic gonadotropin levels, history of previous ectopic pregnancy, pelvic inflammatory disease, tubal surgery, abdominal history, and vaginal bleeding were not significantly different between the 2 groups. The ratio of women with abdominal pain was significantly higher in the ruptured ectopic pregnancy group than in the unruptured group (89.1% vs. 63.8%, respectively, P < .001). Preoperative hemoglobin was lower in the ruptured group compared with the unruptured group (P < .001). Blood loss, postoperative hemoglobin, and blood transfusion were significantly higher in the ruptured group than in the unruptured group (P = .000 and P = .001 for blood loss and blood transfusion, respectively). Multiple logistic regression analysis revealed that abdominal pain and blood loss were associated with ruptured tubal pregnancies (adjusted odds ratio [95% confidence intervals]: 3.42 {1.40, 8.40}; 1.01 {1.005, 1.014}, respectively). In conclusion, early pregnancy with abdominal pain, more parity, and lower preoperative hemoglobin should be aware of the possibility of ruptured ectopic pregnancy. More blood loss, transfusion and lower postoperative hemoglobin were also noted with ruptured ectopic pregnancy. 相似文献
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目的:分析成分输血抢救治疗产科失血性休克,DIC前兆的疗效。方法:选择2007年1月—2008年12月产科DIC前兆患者18例,参照DIC前兆诊断标准与治疗原则,制定成分输血等综合治疗方案,合理输注悬浮红细胞、血小板、新鲜冰冻血浆、冷沉淀等。检测血常规,凝血功能,观察临床治疗效果。结果:18例产科失血性休克,DIC前兆患者成功救治。结论:成分输血在产科失血性休克,DIC前兆抢救治疗中效果显著。 相似文献