高龄白内障患者同轴1.8mm微切口超声乳化术后黄斑区视网膜厚度的临床观察

目的探讨同轴1.8 mm微切口白内障超声乳化吸除人工晶状体植入术对高龄白内障患者黄斑区平均视网膜厚度的影响。方法前瞻性随机对照研究。选择80岁以上高龄老年性白内障患者46例(46只眼),随机分为2组,A组患者23例(23只眼)行1.8 mm白内障超声乳化吸除联合Akreos MI60人工晶状体植入术,B组23例(23只眼)行3.0 mm白内障超声乳化吸除联合Tecnis ZA9003人工晶状体植入术。分别于术前、术后1个月及术后3个月以观察黄斑区平均视网膜厚度的变化。采用SPSS 15.0统计学软件进行数据分析。结果所有患者术后术眼最佳矫正视力均较术前提高,OCT检查结果提示术后1个月A组黄斑区平均视网膜厚度(269.71±32.35)μm,B组黄斑区平均视网膜厚度(278.89±37.39)μm,两组比较差异有统计学意义(P<0.05);术后3个月A组黄斑区平均视网膜厚度(257.86±27.42)μm,B组黄斑区平均视网膜厚度(261.18±25.17)μm,两组比较差异有统计学意义(P<0.05)。结论与传统3.0 mm小切口手术相比,1.8 mm微切口白内障超声乳化吸除术治疗高龄白内障可显著减轻手术对黄斑区视网膜的影响,从而保持稳定的视觉质量。     

1.8 mm同轴微切口白内障超声乳化摘出术的临床观察

背景 随着超声乳化白内障摘出术的发展和进步,探索在更小切口下安全、有效地摘出混浊晶状体的手术方式,从而减轻术中组织的损伤程度,减少术后并发症的发生率逐渐成为临床关注的焦点. 目的 探讨1.8mm同轴微切口超声乳化白内障摘出术的可行性和临床疗效. 方法 本研究为系列病例观察研究.纳入2012年4-5月在内蒙古自治区人民医院眼科拟行超声乳化白内障摘出术的单纯年龄相关性白内障患者32例32眼,其中Ⅱ级核者8例8眼,Ⅲ级核者16例16眼,Ⅳ级核者8例8眼.所有患眼行A型超声测量眼轴长度,IOL度数按照SRK-Ⅱ公式计算.对患眼行盐酸丙美卡因滴眼液表面麻醉,于10:00 ～11:00位用专用手术刀行1.8mm隧道式透明角膜切口,于2:00位做侧切口,其他步骤同常规超声乳化白内障摘出术,并通过1.8mm的切口植入Akreos MI60型人工晶状体(IOL).观察术中超声乳化时间、术后视力和手术并发症.结果 所有术眼手术顺利.各级核患眼术中平均超声乳化有效时间为(7.0±3.6)s,平均超声能量为(15.3±6.1)％.术后1d、1周及1个月时裸眼视力≥0.5的术眼分别为18、28和30眼,分别占56.25％、87.50％及93.75％;术后1个月最佳矫正视力≥0.5和0.8者分别为31眼、26眼,分别占96.88％和81.25％.所有患者术中前房稳定,均无切口部位的热损伤.结论 1.8mm同轴微切口白内障超声乳化摘出术安全、有效,并可通过1.8mm的切口植入IOL,术后疗效良好.     

高龄白内障患者超声乳化术的临床观察

目的观察高龄白内障患者行超声乳化摘除联合人工晶状体植入术的疗效、安全性以及对全身病的影响。方法 2005年至2010年5年间共85例(96只眼)70岁以上的白内障患者于表面麻醉下行白内障超声乳化摘除联合人工晶状体植入术。完善术前检查,严密监测术中及术后的全身情况,观察术后视力恢复情况。结果术后随访2～60个月,视力>0.05而<0.3者3只眼(3.125%),视力<0.5者27只眼(28.12%),>0.6者66只眼(68.75%)。结论高龄患者因全身疾病以及老年性病理生理性特点,眼部手术存在一定风险,但是在充分的术前准备、术中及术后的密切观察,积极处理全身病的前提下,白内障超声乳化摘除联合人工晶状体植入术是安全有效的。     

基于OCTA的白内障超声乳化术后黄斑区视网膜厚度和血管密度分析

目的利用光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)评估白内障超声乳化术后黄斑区视网膜厚度和血管密度的改变。方法纳入47例(57眼)白内障患者,分别在白内障超声乳化术前及术后1周、1个月和3个月使用OCTA检查患眼黄斑中心凹、黄斑中心凹旁、黄斑中心凹周边视网膜厚度和黄斑区视网膜浅层、深层的微血管密度以及黄斑中心凹无血管区(foveal avascular zone,FAZ)面积的变化。结果与术前相比,术后1个月和3个月黄斑中心凹、黄斑中心凹旁和黄斑中心凹周边视网膜全层厚度均显著增加(均为P<0.05),主要表现在内层视网膜的增加上。术后1周、1个月、3个月,黄斑中心凹旁及黄斑中心凹周边视网膜浅层血管密度与术前相比差异均无统计学意义(均为P>0.05),仅术后1个月视网膜深层黄斑中心凹周边血管密度显著高于术前(P<0.05)。术后1个月和3个月黄斑FAZ面积分别为(0.42±0.23)mm²和(0.34±0.17)mm²,显著低于术前的(0.73±0.9...     

同轴1.8 mm微切口超声乳化拦截劈核技术治疗高龄白内障

目的观察同轴1.8 mm微切口超声乳化拦截劈核白内障吸除联合人工晶状体植入术治疗高龄白内障的临床疗效,并与同轴1.8 mm微切口十字架法超声乳化晶状体核手术进行比较。方法 回顾性病例对照研究。选择85岁以上高龄年龄相关性白内障患者42例（42眼）,采用随机数字表法分为2组。拦截劈核组：同轴1.8 mm微切口超声乳化拦截劈核白内障吸除联合人工晶状体植入手术21眼;十字架法超核组：同轴1.8 mm微切口十字架法超声乳化晶状体核白内障吸除联合人工晶状体植入手术21眼。分别记录2组的平均超声能量（AVE）和有效超声时间（EPT）,观察2组患者的术后视力和角膜内皮细胞密度。采用独立样本t检验进行数据分析。结果 2组AVE、EPT比较差异有统计学意义（t=3.958、3.175,P＜0.01）。术后l d拦截劈核组的视力与十字架法超核组比较差异有统计学意义（t=3.976,P＜0.01）,术后1周、1个月、3个月2组视力差异无统计学意义（t=0.496、0.176、0.216,P＞0.05）。术后l d、1周、1个月、3个月拦截劈核组角膜内皮细胞密度高于十字架法超核组,差异有统计学意义（t=8.653、6.076、2.202、2.133,P＜0.01）。2组患者术中前房稳定,均无切口热损伤。结论 对高龄年龄相关性白内障患者,同轴1.8 mm微切口超声乳化拦截劈核白内障吸除联合人工晶状体植入术缩短了术中超声乳化的时间,减小了平均超声能量,对角膜内皮的影响小,术后视力恢复快,降低了手术风险。     

白内障超声乳化吸除术与小切口摘除术后黄斑厚度的对比分析

目的比较白内障超声乳化吸除术与小切口摘除术后患者黄斑厚度的变化。方法回顾分析接受两种手术方式摘除白内障的患者共48例（48只眼）（超声乳化组24例,小切口组24例）在术后第1、7、28天,进行相干光断层扫描（OCT）检查,分析黄斑厚度的变化情况。结果术后第1天,超声乳化组与小切口组患者的黄斑厚度分别是（189.3±31.2）μm、（190.7±24.1）μm,两者间差异不具有统计学意义（P=0.23）;术后第7天,超声乳化组患者黄斑厚度值为（192.4±14.6）μm,小切口组患者的黄斑厚度为（199.2±34.5）μm,两者差异具有统计学意义（P=0.03）;术后第28天,超声乳化组患者黄斑厚度（194.5±18.4）μm与小切口组患者黄斑厚度（203.9±20.8μm）的差异更明显（P=0.01）。结论小切口组患者相对于超声乳化组患者其黄斑厚度的增加更为明显,但所有患者黄斑厚度的改变均未引起明显的临床症状及黄斑水肿。     

同轴微切口白内障超声乳化术后角膜散光的临床观察

目的:评价2.2mm同轴微切口白内障超声乳化手术后角膜散光的变化。方法:老年性白内障患者56例78眼,将患者随机分为2组,2.2mm组38眼,3.0mm组40眼,分别行2.2mm同轴微切口白内障超声乳化联合人工晶状体(IOL)植入术及3.0mm常规白内障超声乳化联合IOL植入术,术后1,3mo评价术眼裸眼视力(uncorrected visual acuity,UCVA)、角膜散光、术源性角膜散光(surgically induced astigmatism,SIA)。结果:术后1mo,2.2mm组角膜散光为0.85±0.42D,3.0mm组角膜散光为1.18±0.37D,两组角膜散光比较有统计学差异(P<0.05)。术后3mo,2.2mm组角膜散光为0.74±0.40D,3.0mm组角膜散光为1.00±0.30D,两组角膜散光比较有统计学差异(P<0.05)。术后1mo和3mo,3.0mm组的SIA大于2.2mm组(P<0.05),3.0mm组术后1mo平均SIA大于术后3mo平均SIA(P<0.05),2.2mm组术后1mo和3mo SIA没有统计学差异(P>0.05)。术后UCVA,在术后1mo和3mo,2.2mm组均优于3.0mm组。结论:2.2mm同轴微切口白内障超声乳化手术后能产生更小的SIA和更好的UCVA。     

白内障超声乳化术后黄斑区光学相干断层扫描观察

目的 应用光学相干断层扫描(optical coherence tomography,OCT)观察白内障超声乳化术后黄斑区视网膜的变化.方法 回顾性分析2011年9月至2012年6月间行白内障超声乳化吸除联合人工晶状体植入术,且术中无并发症的单纯老年性白内障患者102例(138眼)的临床资料.术前、术后1周及1个月对所有术眼行视力和黄斑区OCT检查,观察术眼黄斑中心视网膜的变化.采用SPSS13.0软件对检查结果进行统计分析.结果 138眼术前最佳矫正视力0.07～0.40,OCT检查显示黄斑中心视网膜形态结构均无明显异常,黄斑中心厚度(central fovea thickness,CF、)为(239.72±12.31) μm;138眼成功施行超声乳化术,术后视力均有不同程度提高,眼部无明显炎症反应,眼底镜下未见黄斑区异常;术后1周和1个月OCT检查均未发现黄斑囊样水肿,CFT分别为(248.33±10.87) μm和(241.29±9.68) μm,较术前均略有增加,差异均无统计学意义(均为P＞0.05).结论 单纯老年性白内障患者成功施行超声乳化吸除联合人工晶状体植入术后短期内平均CFT较术前有所增加,术后OCT检查未发现黄斑囊样水肿.     

糖尿病患者白内障术后黄斑区视网膜结构的变化

目的：本临床研究旨在使用相干光学断层扫描(optical coherence tomography,OCT)手段检测术后患者的微血管状况,并且定量检测糖尿病患者术前和术后不同时期的黄斑区视网膜的变化。

方法：纳入白内障手术患者共89例111 眼,其中对照组(A组)共40例59眼,为非糖尿病的白内障患者; 实验组(B组)有49例52 眼,均确诊为2型糖尿病2a以上。所有患者在术前行常规的检测,如视力、最佳矫正视力、眼压、白内障混浊程度等。最后进行术后常规检查,于术前、术后1d,1wk,1mo行OCT检测黄斑区视网膜的变化。复查时检查患者视力、眼压、人工晶状体位置和眼底情况。

结果：单纯白内障患者较患有糖尿病合并白内障的患者,在白内障手术之后的最佳矫正视力更好,差异有统计学意义(χ²=8.38,P=0.004)。光学相干断层扫描呈现：(1)糖尿病患者接受白内障手术后1wk黄斑中心凹视网膜厚度就有了显著的增厚。而非糖尿病患者术后1mo黄斑中心凹视网膜才出现显著的增厚现象。(2)糖尿病患者接受白内障手术后1d黄斑中心凹神经上皮层视网膜厚度就有了显著的增厚。而非糖尿病患者术后1mo黄斑中心凹神经上皮层视网膜才出现显著的增厚现象。(3)糖尿病患者接受白内障手术后1wk黄斑中心凹色素上皮层视网膜厚度就有了显著的增厚,在1mo之后恢复正常。而非糖尿病患者术后1mo黄斑中心凹色素上皮层视网膜才出现显著的增厚现象。

结论：糖尿病合并白内障较单纯白内障的患者术后黄斑水肿发生几率更高,且水肿程度更加严重。血-视网膜屏障破坏是超声乳化白内障吸除术后视网膜损伤的主要原因。黄斑中心凹视网膜厚度增加越明显,术后视力恢复越差。     

正常人黄斑厚度及视盘旁神经纤维频域OCT分析

目的 应用频域OCT(spectral domain Optical Coherence Tomography,SD-OCT)分析正常人眼黄斑厚度、体积及视盘旁神经纤维的分布情况.方法 应用频域OCT对62名124只眼正常人(21～58岁)黄斑及视盘旁进行快速扫描,测量正常眼中心/小凹厚度(Central point thickness,CPT),黄斑部直径为3mm圆形区域内9个分区内平均厚度(Th)及体积(V);同时测量视盘旁直径为3.4mm圆形区域神经纤维分布情况.入组标准:矫正视力20/20,眼压正常,没有已知眼病.结果 124只正常眼中心小凹平均厚度为(215.11±15.475)μm,中心区为(255.56±16.709)μm),黄斑区厚度图呈开口向颞侧的马蹄形,在所有ETDRS区域中,鼻外象限厚度最大(352.87±15.886)μm;中心凹鼻侧厚度及体积大于颞侧(P<0.05);在内环区域,上下方视网膜厚度及体积无明显差异;在外环区域,上下方视网膜厚度及体积差异有统计学意义(P<0.05);视盘旁神经纤维的分布,颞下方神经纤维分布最多,鼻侧神经纤维最少差异有统计学意义.结论 应用频域OCT测量,正常人眼黄斑部中心小凹厚度为(215.11±15.475)μm,中央区为(255.56±16.709)μm,神经纤维层厚度与以往时域OCT测量结果基本一致.频域OCT成像清晰,能够精确测量黄斑视网膜厚度及视盘旁神经纤维分布情况,可为临床诊治黄斑及视神经病变提供客观、定量的指标.

Abstract：

Objective To determine normal values for macular thickness, volume and peripapillary retinal nerve fiber layer thickness(RNFL)measured by spectral domain Optical Coherence Tomography (SD-OCT)in subjects with no known retinal disease and to examine the relationship of RNFL with macular thickness. Methods Sixty-two healthy adults(124 eyes, 21-58 years old)with no known eye disease,best-corrected visual acuity 20/20, and normal intraocular pressure were enrolled. All subjects underwent a complete ophthalmologic examination to rule out any retinal diseases or glaucoma. All the OCT scans were performed by a single operator, Central point thickness(CPT)and retinal thickness(Th)in 9 Early Treatment Diabetic Retinopathy Study(ETDRS)subfields, including central subfield(CSF), were analyzed. Statistical analyses were carried out using the analysis of variance. RNFL thickness was measured around the optic nerve head using 16 automatically averaged, consecutive circular B-scans with 3.4 mm diameter. The automatically segmented RNFL thickness was divided into 7 segments. Results Overall, the mean CPT was(215.11±15.475)μ m, and mean CSF was(255.56± 16.709)μ m. The macular thickness mapping in normal persons was "horse shoe" shaped open to the temporal side. Among the ETDRS subfields, the outer nasal quadrant had the maximum thickness(352.87± 15.886)μ m. The nasal quadrant had a larger thickness and volume than temporal side(P 0.05); in the inner circle area, there was no difference between the superior and inferior retinal average thickness; on the contrary, there was a significant difference between the superior and inferior retinal average thickness and volume in outer circle area. While the distribution of peripapillary retinal nerve fiber also had marked difference. The inferior-temporally side had the most, while the nasal side had the least. Conclusions Normative values for macular thickness in otherwise healthy eyes ware measured to be(215.11 ±15.475)μ m(CPT)and(255.56± 16.709)μ m(CSF)using commercially available Spectralis SD-OCT. Normal RNFL results with SD-OCT are comparable to those reported with time-domain OCT. Due to the legible imaging characters, the SD-OCT can measure normal macular thickness and the distribution of peripapillary retinal nerve fiber accurately, which can provide objective and quantitative indexs for diagnosis and therapy of macular disease and optical neuropathy.     

白内障超声乳化术中前房注入头孢呋辛钠后黄斑厚度的测量

目的:了解白内障超声乳化术中前房注入头孢呋辛钠后黄斑厚度的变化。方法:前瞻性临床对照研究。药物组前房内注入头孢呋辛钠,对照组是前房内注入灌注液。入选患者分为4 组: <60岁药物组,<60 岁对照组,≥60 岁药物组和≥60 岁对照组。分别于术前,术后1,6mo 光学相干断层扫描测量黄斑厚度。结果:术后 1mo,≥60 岁药物组在中心凹、内下区、颞内区和外下区区域的厚度大于其他三组。术后 6mo,只有≥60岁药物组的内下区的厚度大于其他三组。术后 1mo,与各自术前的黄斑厚度相比,≥60 岁药物组在中心凹、内下区、颞内区和外下区区域的增加的厚度大于其他三组。术后6mo,≥60 岁药物组的中心凹和内下区的增加的厚度大于其他三组。结论:白内障术后黄斑厚度增加在术后 6mo 尚不能恢复到术前状态。相对于较年轻患者,超过 60 岁的白内障患者在术中使用头孢呋辛钠会在术后1mo 黄斑厚度增加更多。     

正常人黄斑厚度及视盘旁神经纤维频域OCT分析

Objective To determine normal values for macular thickness, volume and peripapillary retinal nerve fiber layer thickness(RNFL)measured by spectral domain Optical Coherence Tomography (SD-OCT)in subjects with no known retinal disease and to examine the relationship of RNFL with macular thickness. Methods Sixty-two healthy adults(124 eyes, 21-58 years old)with no known eye disease,best-corrected visual acuity 20/20, and normal intraocular pressure were enrolled. All subjects underwent a complete ophthalmologic examination to rule out any retinal diseases or glaucoma. All the OCT scans were performed by a single operator, Central point thickness(CPT)and retinal thickness(Th)in 9 Early Treatment Diabetic Retinopathy Study(ETDRS)subfields, including central subfield(CSF), were analyzed. Statistical analyses were carried out using the analysis of variance. RNFL thickness was measured around the optic nerve head using 16 automatically averaged, consecutive circular B-scans with 3.4 mm diameter. The automatically segmented RNFL thickness was divided into 7 segments. Results Overall, the mean CPT was(215.11±15.475)μ m, and mean CSF was(255.56± 16.709)μ m. The macular thickness mapping in normal persons was "horse shoe" shaped open to the temporal side. Among the ETDRS subfields, the outer nasal quadrant had the maximum thickness(352.87± 15.886)μ m. The nasal quadrant had a larger thickness and volume than temporal side(P 0.05); in the inner circle area, there was no difference between the superior and inferior retinal average thickness; on the contrary, there was a significant difference between the superior and inferior retinal average thickness and volume in outer circle area. While the distribution of peripapillary retinal nerve fiber also had marked difference. The inferior-temporally side had the most, while the nasal side had the least. Conclusions Normative values for macular thickness in otherwise healthy eyes ware measured to be(215.11 ±15.475)μ m(CPT)and(255.56± 16.709)μ m(CSF)using commercially available Spectralis SD-OCT. Normal RNFL results with SD-OCT are comparable to those reported with time-domain OCT. Due to the legible imaging characters, the SD-OCT can measure normal macular thickness and the distribution of peripapillary retinal nerve fiber accurately, which can provide objective and quantitative indexs for diagnosis and therapy of macular disease and optical neuropathy.     

白内障术后黄斑区光学相干断层扫描动态观察

目的：观察白内障术后黄斑厚度的改变。方法：将126例白内障患者分为两组,分别行常规白内障超声乳化联合人工晶状体植入术64例和小切口非超声乳化联合人工晶状体植入术62例。两组术前、术中无并发症,术前及术后1,3mo黄斑区行OCT检查,观察两组术后黄斑厚度及视力变化。本研究采用SPSS 17.0统计学软件处理,每组术前、后采用配对t检验对数据进行统计学处理; 两组间术前、后分别采用独立样本t检验对数据进行统计学处理,取α=0.05检验水准。结果：两组术后黄斑厚度变化：超声乳化组：术前、术后1,3mo黄斑厚度分别为241.3±10.9, 279.7±16.5,245.6± 12.6μm。术后1mo与术前比较差异有显著差异（P〈0.01）; 术后3mo与术前比较,差异无统计学差异（P〉0.05）; 术后1mo与3mo比较有统计学差异（P〈0.05）。有3例术后1mo出现黄斑囊样水肿,2例术后3mo完全消退。小切口非超声乳化组：术前、术后1,3mo黄斑厚度分别为240.5±11.9,280.9±16.8,246.6±13.2μm。黄斑厚度术后1mo与术前比较有显著统计学差异（P〈0.01）; 术后3mo与术前比较,无统计学差异（P〉0.05）; 术后1mo与3mo比较有统计学差异（P〈0.05）。有2例术后1mo出现黄斑囊样水肿,2例术后3mo完全消退。超声乳化组与小切口非超声乳化组,两组间术前、术后1,3mo分别比较均无统计学差异（P均〉0.05）。结论：无论选择白内障超声乳化还是小切口非超声乳化白内障联合人工晶状体植入,术后1mo黄斑厚度明显增加,证明术后造成黄斑水肿; 术后3mo厚度基本恢复术前。黄斑增厚与术式选择无明显关系。     

Correlations between optical coherence tomography measurement of macular thickness and visual acuity after cataract extraction

PURPOSE: To investigate correlations between optical coherence tomography macular thickness measurements and visual acuity after cataract surgery. METHODS: Sixty-two patients underwent routine cataract surgery as part of a randomized clinical trial of oral Cox-2 inhibitor prophylaxis of cystoid macular oedema. Optical coherence tomography was used to quantify several parameters of macular thickness. Optical coherence tomography measurements were obtained before surgery, day one, week two and week six after surgery. These measurements were then correlated with logMAR best-corrected visual acuity. RESULTS: Optical coherence tomography macular thickness parameters increased after surgery by up to 20%. A significant correlation was identified between foveal minimum macular thickness and best-corrected visual acuity at day one and week six after surgery. Other macular parameters failed to show any significant correlation. At day one and week six, the 10 patients with greatest macular thickness had significantly lower visual acuity than the other patients. CONCLUSION: In this study routine cataract surgery caused an increase in macular thickness. Some significant positive correlations between macular thickness and best-corrected visual acuity were found, although not for all parameters or time points. There may be a threshold relationship between degree of foveal anatomic change and significant loss of visual acuity.     

胰岛素强化治疗后黄斑区视网膜厚度的早期观察

目的 应用海德堡视网膜断层扫描仪(HRTⅡ)和光学相干断层扫描(optical coherence tomography,OCT),对初次进行胰岛素强化治疗的2型糖尿病患者黄斑区视网膜厚度进行评价.方法 前瞻性病例研究.对40例初次进行胰岛索强化治疗的合并非增殖期糖尿病性视网膜病变的2型糖尿病患者,分别用HRTⅡ和OCT检查胰岛素强化治疗前,治疗后1月、3月和6月的黄斑区水肿指数e值和视网膜厚度变化并进行比较.结果 黄斑区一环、二环和三环胰岛素强化治疗后1月、3月、6月的e值与强化治疗前比较均差异无统计学意义(P＞0.05);黄斑区一环胰岛素强化治疗后1月、3月、6月OCT所测的视网膜厚度值分别与强化治疗前视网膜厚度值比较均差异无统计学意义(P＞0.05);二环强化治疗后1月OCT所测的视网膜厚度值与治疗前相比有统计学意义(P＝0.019),治疗后3月、6月与治疗前差异无统计学意义(P＞0.05);三环胰岛素强化治疗后1月、3月OCT所测的视网膜厚度值与治疗前相比有统计学意义(分别为P =0.010、0.000,),治疗后6月与治疗前差异无统计学意义(P＞0.05).结论 短期胰岛素强化治疗对合并非增殖期糖尿病视网膜病变的2型糖尿病性患者的黄斑厚度改变并无明显影响.     

Correlation between foveal structure and visual outcome following macular hole surgery: a spectral optical coherence tomography study

PURPOSE: The aim of this paper is to evaluate the retinal structure after macular hole surgery and to study the correlation of structural findings with final functional outcomes, using high-speed, high-resolution spectral optical coherence tomography (SOCT). METHODS: Sixty-eight eyes of 60 patients with full-thickness macular holes were included in the study. All patients underwent pars plana vitrectomy with trypan blue staining and internal limiting membrane (ILM) peeling. Patients were evaluated by SOCT, with 6 mum axial and 12-18 mum transverse resolution and three-dimensional images of the retina. RESULTS: There were four different types of macular hole closure: U-shape, V-shape, irregular and flat/open. The following retinal abnormalities were observed in postoperative scans: photoreceptor irregularities, lack of photoreceptors (photoreceptor defect), cysts in outer retinal layers, nerve fiber layer defects, lesion of all retinal layers, and RPE defects. It was possible to evaluate photoreceptor defects on a three-dimensional image. Retinal thickness in the fovea was also measured. CONCLUSIONS: Because of excellent resolution, SOCT is capable of visualization of retinal defects after macular hole surgery. Three-dimensional examination is adequate for evaluation of photoreceptor defects. Good postoperative visual acuity is correlated with U-shape closure, normal foveal thickness and absence of photoreceptor layer defects.     

光学相干断层扫描评价高度近视黄斑裂孔伴视网膜脱离的玻璃体手术疗效

目的 光学相干断层扫描(Optical Coherence Tomography，OCT)评价高度近视黄斑裂孔伴视网膜脱离行玻璃体手术的疗效。方法 回顾性分析17例(17眼)高度近视黄斑裂孔伴视网膜脱离行玻璃体切除术的住院病史资料，术后平均随访10月，所有病例均行以下检查：OCT、裂隙灯生物显微镜、三面镜、90D前置镜、验光。结果 术后OCT表现有3种：黄斑裂孔闭合2眼(11．8％)，黄斑裂孔未闭合但视网膜复位12眼(70．6％)，黄斑裂孔未闭合伴视网膜浅脱离3眼(17．6％)。预后情况与黄斑区色素上皮和脉络膜的健康状况以及黄斑裂孔的大小有关。结论 高度近视黄斑裂孔伴视网膜脱离行玻璃体手术的裂孔闭合率低。OCT是术后随访的有效手段。