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1.
Mohammad El-Sayed Mojahed Elsaeid Mohamed Thabet Mohamed Galal El-Khateeb Ashraf Elsayed Morgan 《Auris, nasus, larynx》2018,45(3):407-411
Objective
Myasthenia gravis (MG) is an archetypic disorder of neuromuscular junctions (NMJs) and autoantibody-mediated disease causing fatigable weakness of skeletal muscles with an ocular onset in up to 85%. The aim of this study was to detect extra ocular muscles (EOMs) abnormalities in MG patients using ocular vestibular evoked myogenic potential (oVEMP) n10 response.Methods
The oVEMP was performed on 40 myasthenia gravis patients that were divided into three groups: newly diagnosed (10 patients), uncontrolled on treatment (15 patients) and controlled on treatment (15 patients) groups in addition to a control group of 10 subjects. Also a comparison of oVEMP response was held between patients with generalized and ocular MG.Results
The oVEMP n10 showed significant difference between the 3 study groups and the control. The n10 showed no significant difference between the newly diagnosed group and the other 2 groups. There was also significant difference between uncontrolled and controlled on treatment group and between generalized and ocular types of myasthenic patients.Conclusion
The oVEMP can be usefully used in diagnosis of new MG patients as regard n10 amplitude, threshold and AR except n10 latency with no therapeutic or monitoring value of oVEMP in MG. 相似文献2.
Elshahat Ibrahem Ismail Ashraf Elsayed Morgan Mohamed Moustafa Abdeltawwab 《Auris, nasus, larynx》2018,45(5):980-984
Objective
To check the value of home particle repositioning maneuver in the prevention of the recurrence of posterior canal benign paroxysmal positional vertigo (pc-BPPV).Methods
In this study, patients diagnosed as unilateral posterior canal BPPV were selected following an accurate evaluation using video goggle VNG system. All patients were managed by particle repositioning maneuver (PRM). Patients were instructed to do home PRM once weekly for five years. Then, they were divided into two groups (according to choice of patient to do PRM). The first group (control group) consisted of 144 patients who did not do home PRM; whereas the second group (study group) included 165 patients who performed home PRM. All patients (control & study groups) were followed up every four months for five years.Results
The study found out that the recurrence rate of pc-BPPV in control group was 33 patients in the first year (27.2%), 11 patients in second year (9%), 5 patients in third year (4%), 3 patients in fourth year (2.5%) and 3 patients in fifth year (2.5%). The recurrence of pc-BPPV in the treated side (study group) of patients was reported as 5 patients in the first year (3.5%), 3 patients in the second year (2%), 2 patients in the third year (1.4%), 2 patients in the fourth year (1.4%), and 1 patient in the fifth year (0.7%). There was statistically significant difference between the control and the study groups regarding the recurrence rates in the first year follow up which was the highest in first four months.Conclusion
Home particle repositioning maneuver has the capacity to prevent the recurrence of pc-BPPV. It proved to be more successful and functional in minimizing the recurrence of the disease in the study than in the control group. Hence, home particle repositioning maneuver is highly recommended for one year at least in pc-BPPV. 相似文献3.
Mariah Guieiro Alves dos Reis Ricardo Guimarães Marim Luis Ricardo Martinhão Souto 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(2):159-165
Introduction
The ear deformity Tanzer type V, also known as prominent ears, is the most common genetic defect of the pinna. The surgery designed for its correction is known as otoplasty. This esthetic surgery can be performed using different techniques, which requires great skill of its operator.Objective
The purpose of this work is the development of a new tool for otoplasty techniques training, aimed on the possibility to minimize errors during the otoplasty.Methods
Synthetic molds of the external ear from patients with Tanzer type V deformity were made, using silicone material and rayon.Results
The main procedures of otoplasty could be performed in the molds made of silicone and rayon with a good esthetic result.Conclusion
The elaborated molds had identical size and shape of a human ear and could be positioned in the same shape of the patient ears. Thus, the synthetic molds were presented as promising simulation tools for the training and surgical enhancement of otoplasty, especially for doctors beginners. 相似文献4.
Ali Bayram Mehmet Kalkan Nuri Ünsal Ahmet Kale Bekir Küçük Cemil Mutlu 《American journal of otolaryngology》2018,39(3):290-292
Objective
The aim of the present study was to investigate the influence of blindness on ocular vestibular evoked myogenic potentials (oVEMP) responses.Methods
Thirty-one subjects with unilateral blindness (UB group) and 25 age and sex-matched healthy subjects (control group) were recruited for the present study. The oVEMP responses including latency, amplitude and amplitude asymmetry ratio (AR) were measured and compared between the blind side, the contralateral eye of the UB group and the control subjects.Results
Ocular VEMP recordings were obtained from 29 of 31 patients (93.5%) for the blind side of the UB group. There was no significant difference in terms of latency, amplitude and AR value between the blind side and the contralateral eye of the UB group and the control subjects.Conclusion
Clear oVEMP recordings can be elicited as long as the eyeball and extraocular muscles are preserved in a blind eye. 相似文献5.
Maria Eduarda Di Cavalcanti Alves de Souza Klinger Vagner Teixeira da Costa Pedro de Lemos Menezes 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(3):381-388
Introduction
Caffeine can be considered the most consumed drug by adults worldwide, and can be found in several foods, such as chocolate, coffee, tea, soda and others. Overall, caffeine in moderate doses, results in increased physical and intellectual productivity, increases the capacity of concentration and reduces the time of reaction to sensory stimuli. On the other hand, high doses can cause noticeable signs of mental confusion and error induction in intellectual tasks, anxiety, restlessness, muscle tremors, tachycardia, labyrinthine changes, and tinnitus.Objective
Considering that the vestibular evoked myogenic potential is a clinical test that evaluates the muscular response of high intensity auditory stimulation, the present systematic review aimed to analyze the effects of caffeine on vestibular evoked myogenic potential.Methods
This study consisted of the search of the following databases: MEDLINE, CENTRAL, ScienceDirect, Scopus, Web of Science, LILACS, SciELO and ClinicalTrials.gov. Additionally, the gray literature was also searched. The search strategy included terms related to intervention (caffeine or coffee consumption) and the primary outcome (vestibular evoked myogenic potential).Results
Based on the 253 potentially relevant articles identified through the database search, only two full-text publications were retrieved for further evaluation, which were maintained for qualitative analysis.Conclusion
Analyzing the articles found, caffeine has no effect on vestibular evoked myogenic potential in normal individuals. 相似文献6.
Eulalia Sakano Emanuel S.C. Sarinho Alvaro A. Cruz Antonio C. Pastorino Edwin Tamashiro Fábio Kuschnir Fábio F.M. Castro Fabrizio R. Romano Gustavo F. Wandalsen Herberto J. Chong-Neto João F. de Mello Luciana R. Silva Maria Cândida Rizzo Mônica A.M. Miyake Nelson A. Rosário Filho Norma de Paula M. Rubini Olavo Mion Paulo A. Camargos Dirceu Solé 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(1):3-14
Introduction
The guidelines on allergic rhinitis aim to update knowledge about the disease and care for affected patients. The initiative called “Allergic Rhinitis and its Impact on Asthma”, initially published in 2001 and updated in 2008 and 2010, has been very successful in disseminating information and evidence, as well as providing a classification of severity and proposing a systemized treatment protocol. In order to include the participation of other medical professionals in the treatment of allergic rhinitis, it is important to develop algorithms that accurately indicate what should and can be done regionally.Objective
To update the III Brazilian Consensus on Rhinitis – 2012, with the creation of an algorithm for allergic rhinitis management.Methods
We invited 24 experts nominated by the Brazilian Association of Allergy and Immunology, Brazilian Association of Otorhinolaryngology and Head and Neck Surgery and Brazilian Society of Pediatrics to update the 2012 document.Results
The update of the last Brazilian Consensus on Rhinitis incorporated and adapted the relevant information published in all “Allergic Rhinitis and its Impact on Asthma” Initiative documents to the Brazilian scenario, bringing new concepts such as local allergic rhinitis, new drugs and treatment evaluation methods.Conclusion
A flowchart for allergic rhinitis treatment has been proposed. 相似文献7.
Maria Stella Arantes do Amaral Thiago A. Damico Alina S. Gonçales Ana C.M.B. Reis Myriam de Lima Isaac Eduardo T. Massuda Miguel Angelo Hyppolito 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(5):560-565
Introduction
Cochlear Implant is a sensory prosthesis capable of restoring hearing in patients with severe or profound bilateral sensorineural hearing loss.Objective
To evaluate if there is a better side to be implanted in post-lingual patients.Methods
Retrospective longitudinal study. Participants were 40 subjects, of both sex, mean age of 47 years, with post-lingual hearing loss, users of unilateral cochlear implant for more than 12 months and less than 24 months, with asymmetric auditor reserve between the ears (difference of 10 dBNA, In at least one of the frequencies with a response, between the ears), divided into two groups. Group A was composed of individuals with cochlear implant in the ear with better auditory reserve and Group B with auditory reserve lower in relation to the contralateral side.Results
There was no statistical difference for the tonal auditory threshold before and after cochlear implant. A better speech perception in pre-cochlear implant tests was present in B (20%), but the final results are similar in both groups.Conclusion
The cochlear implant in the ear with the worst auditory residue favors a bimodal hearing, which would allow the binaural summation, without compromising the improvement of the audiometric threshold and the speech perception. 相似文献8.
Keiko Ogawa-Ochiai Keigo Osuga Kuniaki Hidaka Kengo Nakahata Yuko Tazuke Yoshifumi Yamamoto Shuichiro Uehara Hiroomi Okuyama 《Auris, nasus, larynx》2018,45(1):190-193
Objective
To present the efficacy of Japanese-traditional medicine (Kampo) for a case with vascular malformation.Methods
A case study and literature review.Patient
A 62-year-old female presented with dysphagia and spitting blood. Esophagogastroduodenoscopy showed a longitudinal lobulated and septated mass in the posterior pharynx. On MR imaging, the mass showed hyperintensity on T2-weighted images and heterogeneous enhancement on Gadlinium-enhanced T1-weighted images, suggestive of a low-flow vascular malformation.Intervention
According to the Kampo diagnosis, kamisyouyousan and ninjinyoueito were prescribed to this patient. The effect of Kampo medicine was evaluated with improvement of her symptoms and volumetry of MRI findings.Result
The longitudinal pharyngeal mass was markedly decreased and her symptoms disappeared after 2 years of Kampo administration.Conclusions
Kampo medicine can be a novel alternative therapy for VM. 相似文献9.
José Ferreira Penêda Nuno Barros Lima Leandro Ribeiro Diamantino Helena Bruno Domingues Artur Condé 《Acta otorrinolaringologica espanola》2018,69(2):105-109
Introduction
Cochlear damage is frequent in long-term aminoglycosides therapy or chemotherapeutic treatments with platinum-based agents. Despite its prevalence, it is currently underestimated and underdiagnosed. A monitoring protocol is vital to the early detection of cochleotoxicity and its implementation is widely encouraged in every hospital unit. Our aim was to elaborate a cochleotoxicity monitoring protocol for patients treated with platinum compounds or aminoglycosides antibiotics.Methods
PubMed® database was searched using terms relevant to drug cochleotoxicity in order to identify the most adequate protocol. Several articles and guidelines influenced our decision.Results
There is no consensus on a universal monitoring protocol. Its formulation and application rely heavily on available resources and personnel. High-frequency audiometry and otoacoustic emissions play an important role on early detection of cochleotoxicity caused by aminoglycoside antibiotics and platinum compounds.Conclusion
A cochleotoxicity monitoring protocol consisting on an initial evaluation, treatment follow-up and post-treatment evaluation is proposed. 相似文献10.
Tadao Yoshida Satofumi Sugimoto Masaaki Teranishi Hironao Otake Masahiro Yamazaki Shinji Naganawa Tsutomu Nakashima Michihiko Sone 《Auris, nasus, larynx》2018,45(1):33-38
Objective
To examine endolymphatic hydrops (EH) using magnetic resonance imaging (MRI) in patients with definite Ménière’s disease (MD) and those with nonotological diseases.Methods
We studied 32 patients with unilateral MD, 10 patients with bilateral MD and 21 patients with control ears who had other benign diseases not associated with hearing or vestibular dysfunction. The mean age of the subjects was 54.0 years (range 27–74) in the MD group and 56.1 years (range 24–79) in the control group. Using MRI, the degree of EH was classified as none, mild and significant in the cochlea and vestibule separately. The ratio of the area of endolymphatic space to the vestibular fluid space was calculated for the vestibule. The duration of MD was defined as the months between the first attack of MD and the MRI study.Results
EH was present in the cochlea of 45/52 affected ears of patients with MD (87%) and in 16/42 control ears (38%). Significant cochlear hydrops was present in 37/52 affected ears (71%) and in 4/42 control ears (10%). EH in the vestibule was present in 49/52 affected ears (94%) and in 3/42 control ears (7%). Significant vestibular hydrops was present in 40/52 affected ears (77%) and in none of the 42 control ears. There was no relationship between the degree of EH and its duration. Using a cut off value for the relative size of EH in the vestibule of 41.9%, the test had a sensitivity of 88.5% and a specificity of 100% to diagnose definite MD.Conclusion
Cochlear EH was occasionally observed in control ears on MRI, as in normal temporal bone specimens. The presence or absence and degree of vestibular EH were significantly different between ears with MD and control ears. EH in the vestibule might be a specific predictor of definite MD. 相似文献11.
S. Daldoul A. Moussi S. Sayari M. Ben Moussa 《European annals of otorhinolaryngology, head and neck diseases》2017,134(1):43-45
Introduction
The treatment of ischaemic stenosis of colon interposition for oesophageal replacement remains poorly defined.Case report
We report two cases of patients operated for ischaemic stenosis of the cervical extremity of the colon interposition for caustic stenosis of the oesophagus. Treatment consisted of resection of the stenosis with creation of a new cervical anastomosis after complete release of the colon graft via a neck and upper midline incision in one patient and a new ileocolic graft exclusively replacing the stenotic segment of the oesophagoplasty in the second patient.Discussion
These two cases illustrate the complex treatment modalities required for this complication.Conclusion
The treatment of choice of ischaemic stenosis of colon interposition is resection with creation of a new anastomosis, but repeat graft may sometimes be the only available treatment option. 相似文献12.
P. Clarós J.V.F. Fokouo A. Clarós 《European annals of otorhinolaryngology, head and neck diseases》2017,134(1):63-65
Introduction
Trauma of the orbit and eyeball is common, but intraorbital bullet is a relatively rare event.Clinical cases
The authors report the management of a patient with chorioretinitis sclopetaria secondary to a gunshot wound twenty years previously.Discussion
The clinical, diagnostic and therapeutic aspects of this unusual case of intraorbital foreign body are discussed. 相似文献13.
S. Anajar A. Lakhbal R. Abada M. Mahtar 《European annals of otorhinolaryngology, head and neck diseases》2017,134(3):205-206
Introduction
Keratoameloblastoma is an extremely rare odontogenic tumor, as only 18 cases have been reported in the literature.Case report
The authors report a case of keratoameloblastoma in a 32-year-old woman and review the literature concerning the clinical features, radiological appearance, histopathological findings and treatment options.Discussion
Keratoameloblastoma is a rare tumor observed more frequently in males (sex ratio: 3:1) characterized by extensive keratin production in odontogenic islets and fibrous stroma. 相似文献14.
Objective
The main cause of primary hyperparathyroidism is a single parathyroid adenoma. Parathyroid lipoadenomas contain abundance of fat cells. Because of these histological features, they can mimic normal parathyroid tissue at the histopathologic examination and radiological imaging could be difficult to localize lipoadenomas.Clinical Presentation
In this case report, we present three cases of functional parathyroid lipoadenomas.Conclusion
Preoperative imaging modalities often can’t localize lipoadenoma. In our cases, SPECT has seen more successful than ultrasonography or CT. There may not be gender predominance at parathyroid lipoadenomas. Intraoperative pathology consultation and rapid biochemical workup can help the surgeon in difficult cases. 相似文献15.
Rintaro Shimazu Mihoko Yamamoto Akimichi Minesaki Yuichiro Kuratomi 《Auris, nasus, larynx》2018,45(3):522-526
Objective
In this study, we evaluated pathological changes in the tooth and pharynx of GERD rats to elucidate the association between gastric acid reflux and oral and pharyngeal diseases.Methods
An experimental rat model of chronic acid reflux esophagitis was surgically created. The oral cavities were observed histologically every 2 weeks until 20 weeks after surgery.Results
At 10 weeks after surgery, molar crown heights in GERD rats were shorter than that in control rats, and inflammatory cell infiltration by gastric acid reflux was found in the periodontal mucosa of GERD rats. Furthermore, dental erosion progressed in GERD rats at 20 weeks after surgery, and enamel erosion and dentin exposure were observed. During the same period, inflammatory cell infiltration was observed in the mucosa of the posterior part of the tongue. These findings suggest that gastric acid reflux may be one of the exacerbating factors of dental erosion, periodontitis and glossitis.Conclusion
We investigated oral changes in an experimental rat model of GERD and observed development of dental erosion, periodontitis and glossitis. Our findings suggested chronic gastric acid reflux may be involved in the pathogenesis of oral disease. 相似文献16.
Jung Ju Han Jung Mee Park Dong Kee Kim So Young Park Shi Nae Park 《Auris, nasus, larynx》2019,46(1):34-37
Objective
This pilot study was performed to investigate the therapeutic effect of Valsalva maneuver on otitis media in adults and to evaluate the prognostic factors for the good response.Methods
Thirty nine ears of 32 adult patients who were diagnosed as otitis media with effusion and managed by one-week Valsalva maneuver (>20/day) without any other medication were included in this study. Its therapeutic efficacy was evaluated and the prognostic factors which predict the response of Valsalva maneuver were analyzed by comparing various clinical and audiological factors between success and failure groups.Results
Mean duration of otitis media in the study subjects was 30.9 days (SD 31.6 days). A success rate of 1-week Valsalva maneuver as a single therapeutic modality was up to 64.1% (25/39 ears) and hearing was significantly recovered in success group. No recurrence or side effects were observed. Successful Valsalva maneuver checked and confirmed as bulging of the tympanic membrane by otoendoscopic examination was an excellent indicator of therapeutic response in a week (p < 0.05). Age, sex, duration of otitis media, history of previous upper respiratory tract infection, initial hearing levels and type of audiogram were not significant prognostic factors for the therapeutic efficacy of Valsalva maneuver.Conclusion
One-week Valsalva maneuver seems to be considered as a first line therapeutic modality in otitis media with effusion in adult patients who demonstrate the successful maneuver result on oto-endoscopic examination. 相似文献17.
Objective
We examined plastic changes in the vestibulo-ocular reflex (VOR) during low-frequency vertical head rotation, a condition under which otolith inputs from the vestibular system are essential for VOR generation.Methods
For adaptive conditioning of the vertical VOR, 0.02 Hz sinusoidal pitch rotation for one hour about the earth’s horizontal axis was synchronized with out-of-phase vertical visual stimulation from a random dot pattern.Results
A vertical VOR was well evoked when the upright animal rotated around the earth-horizontal axis (EHA) at low frequency due to the changing gravity stimulus and dynamic stimulation of the otoliths. After adaptive conditioning, the amplitude of the vertical VOR increased by an average of 32.1%.Conclusion
Our observations showing plasticity in the otolithic contribution to the VOR may provide a new strategy for visual-vestibular mismatch training in patients with otolithic disorders. This low-frequency vertical head rotation protocol also provides a model for investigating the mechanisms underlying the adaptation of VORs mediated by otolith activation. 相似文献18.
Andrea Canale Federico Caranzano Michele Lanotte Alessandro Ducati Francesco Calamo Andrea Albera Michelangelo Lacilla Marco Boldreghini Sergio Lucisano Roberto Albera 《Auris, nasus, larynx》2018,45(6):1159-1165
Objective
Selective unilateral vestibular neurectomy (VN) is considered a reliable surgical treatment in case of recurrent vertigo in Menière’s disease (MD) because of hearing preservation and a minimally invasive posterior fossa retrosigmoid approach. The present study aimed to assess the quality of life and the long-term vestibular function in patients submitted to yearly follow-up after VN because of intractable MD.Methods
Retrospective series of 15 MD patients undergoing retrosigmoid VN for recurrent vertigo. Outcome measures included cVEMPs and oVEMPs (cervical and ocular vestibular evoked myogenic potentials), VHIT (Video Head Impulse Test) and caloric test, besides to DHI (Dizziness Handicap Inventory) and PTA (Pure Tone Audiometry).Results
Mean DHI score resulted within normal values in 74% of patients, significantly correlated to the duration of the follow-up. In the operated side, cVEMPs and oVEMPs have not been elicited respectively in 11 patients (73%) and 13 patients (87%), whereas it was not possible to evoke any response at bithermal caloric test in 4 cases. The gain of VOR from VHIT resulted always below normal values after VN except in one patient, who has also undergone an episode of posterior BBPV. The difference between average PTA threshold before and after VN resulted not significant.Conclusion
The vestibular outcomes prove VN to be an effective and safe surgery in MD; furthermore, the unexpected occurrence of BPPV after VN can justify the presence of neural anastomosis between the inferior vestibular nerve and the cochlear nerve, allowing to still perceive vestibular symptomatology despite of a proper neurectomy. 相似文献19.
Paula Martínez Pascual Paloma Pinacho Martinez Eviatar Friedlander Carlos Martin Oviedo Bartolome Scola Yurrita 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(3):305-310
Introduction
Deep neck infections are defined as suppurative infectious processes of deep visceral spaces of the neck.Objective
The aim of this study is to review different factors that may influence peritonsillar and deep neck infections and may play a role as bad prognosis predictors.Methods
We present a retrospective study of 330 patients with deep neck infections and peritonsillar infections who were admitted between January 2005 and December 2015 in a tertiary referral hospital. Statistical analysis of comorbidities, diagnostic and therapeutic aspects was performed with Excel and SPSS.Results
There has been an increase in incidence of peritonsilar and deep neck infections. Systemic comorbidities such as diabetes or hepatopathy are bad prognosis factors. The most common pathogen was S. viridans (32.1% of positive cultures). 100% of the patients received antibiotics and corticosteroids, 74.24% needed surgical treatment. The most common complications were mediastinitis (1.2%) and airway obstruction (0.9%).Conclusion
Systemic comorbidities are bad prognosis predictors. Nowadays mortality has decreased thanks to multidisciplinary attention and improvements in diagnosis and treatment. 相似文献20.
Arianna Di Stadio Carlo Macro 《Revista brasileira de otorrinolaringologia (English ed.)》2018,84(2):166-172