支气管动脉灌注治疗晚期肺癌

目的 晚期肺癌常有肺门及纵隔淋巴结转移，手术难以切除，对这些患进行支气管灌注，可提高手术切除率和延长患的生存期。材料和方法 我们对２５例经证实的晚期肺癌行支气管动脉灌注，其中男１８例，女７例，肿块最大的９．５ｃｍ×８．２ｃｍ，最小的２．５ｃｍ×２．５ｃｍ。经支气管动脉灌注１次７例，灌注２次１５例，灌注３次３例，结果 灌注后肿块明显缩小２３例，无变化１例。缩小有１５例手术切除，另８例未手术     

直径2cm以下肺孤立结节的CT鉴别诊断

直径２ｃｍ以下肺孤立结节的ＣＴ鉴别诊断马大庆肺内孤立结节的常见疾病是肉芽肿（占５４．０％）、支气管肺癌（占２８．０％）、错构瘤（占６．６％）、转移瘤（占３．５％）和支气管腺瘤（占２．０％）［１］。在直径２ｃｍ以下的肺内孤立结节中，良性结节占４７．３％...     

胃癌术后存活5年4例报告

例１：男性,６１岁,于１９９４年１０月出现吞咽困难,作胃镜诊断为贲门癌。同月作贲门癌切除、食管胃吻合术,术中见肿物５ｃｍ×６ｃｍ×７ｃｍ,浸及浅肌层,病理检查为低分化腺癌无淋巴结转移。术后３周开始以５－氟尿嘧啶为主的联合化疗,１９９４年化疗２个周期,...     

CT导引下同轴穿刺针胸部病变穿刺活检(附48例分析)

目的：探讨同轴穿刺针在胸部病变检中的应用。材料与方法：应用仿Ｇｒｅｅｎ针改制的２０Ｇ同轴穿刺针对４８例胸部病变患者在ＣＴ导向下穿刺活检。其中３８例结节或肿块性病变大小为１．５￣４．２ｃｍ×２．８￣１０．５ｃｍ,平均２．６ｃｍ×５．８ｃｍ;肺实变１０例。结果：４８例病灶共取材１１０次,平均２．３次。组织学标本获取率９３．８％（４５／４８）,恶性病变诊断准确率１００％（２１／２１）,良性病变诊断准确率     

后腹膜巨大恶性神经鞘瘤一例

后腹膜巨大恶性神经鞘瘤一例冯代群患者男，４０岁。右上腹隐痛不适３年，发现包块并逐渐增大５个月。体检：左中上腹可扪及一巨大肿物，婴儿头大小，质中，表面光整，不活动，无压痛。图１ＣＴ平扫，左中上腹可见一巨大囊实性肿块影，大小约２０．７ｃｍ×１３．５ｃｍ×...     

KTP/YAG双波长激光在肺癌手术中的临床应用

目的 总结应用ＫＴＰ／ＹＡＧ双波长激光配合胸外科手术治疗肺癌的经验。方法 １９９５年５月以来为４５例肺癌患者（周围型肺癌３９例,单侧肺转移癌４例,双肺转移癌２例,肿瘤直径１．４￣５．７ｃｍ）行激光手术。应用进口ＫＴＰ／ＹＡＧ双波长激光治疗机,ＫＴＰ激光波长５３２ｎｍ,Ｎｄ：ＹＡＧ激光波长１０６４ｎｍ。术中根据不同病灶及组织结构,分别选择１２￣１５Ｗ的ＫＴＰ激光或３０￣６０Ｗ的Ｎｄ：ＹＡＧ激光对肺叶     

胰腺平滑肌瘤一例

胰腺平滑肌瘤一例魏鼎泰李铭山李华灿龚芸青患者女，２４岁。主诉发现左上腹肿物伴反复疼痛１月余。体检：左中上腹触及一肿物，大小约１８．５ｃｍ×１２．０ｃｍ×１０．０ｃｍ，质中等，肿物固定，表面光滑，边界模糊不清，伴有触、压痛，皮肤色泽正常。实验室检查：（...     

腹膜后炎性假瘤的CT诊断和鉴别诊断

分析经手术病理证实的腹膜后炎性假瘤的ＣＴ增强前后表现，为进一步认识腹膜后炎性假瘤的ＣＴ特征。材料和方法：搜集１９９０年１０月至１９９７年９月经手术病理证实且资料完整的１１例腹膜后炎性假瘤，全部病例均在ＣＴ平扫发现病变后，又静脉团注１００ｍｌ碘海醇（欧乃派克）行增强ＣＴ扫描。结果：１１例ＣＴ增强前、后成像均显示边缘形态不规则的肿块，直径大小为３．５￣５．０ｃｍ；其中８例前缘和侧缘有长短各异（５￣２０     

肺原发恶性纤维组织细胞瘤二例

肺原发恶性纤维组织细胞瘤二例彰俊杰，马子贵，李久珍，时高峰，李彩英例１男，３３岁。因右胸不适，咳嗽，痰带血丝１个月就诊。胸片示右肺中叶３ｃｍ×４ｃｍ大小圆形肿物，密度均匀，边界清楚（图１），诊断为结核瘤。抗傍治疗２年无明显疗效。２年８个月后复查胸片，...     

腹盆生殖细胞瘤的MRI、CT表现

目的：研究腹盆生殖细胞瘤ＭＲＩ、ＣＴ表现。方法：本组８例经病理证实腹盆生殖细胞瘤,均为男性,年龄２１～４８岁,平均年龄３０．０岁。ＭＲＩ检查５例,ＣＴ检查３例。结果：肿瘤位于腹膜后４例,盆间隙４例。肿瘤直径８～２０ｃｍ,４例直径＜１０ｃｍ,４例直径＞１０ｃｍ。圆形、椭圆形３例,不规则状５例。位于腹膜后呈不规则状,内部见囊变及钙化,侵犯周围组织;位于盆内呈境界清之肿块,以推移周围器官改变为主。ＣＴ或ＭＲＩ不易鉴别原发或继发病变。结论：腹盆内生殖细胞瘤在腹膜后和盆间隙表现不同,原发或继发病变表现相似。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.