透明细胞棘皮瘤一例

正透明细胞棘皮瘤是一种罕见的良性表皮肿瘤,临床较少见,且容易被误诊为其他皮肤病,现报告1例笔者近期门诊确诊的患者。临床资料患者,女,37岁。主因右小腿胫前出现结节2年,于2015年8月来就诊。2年前,无明显诱因患者右小腿胫前出现一黄豆大小肤色结节,无痛痒,未予重视。2年间结节大小、形状均无明显改变。患者既往史、个人史均无殊,家族中均无类似患者。系统查体无明显异常。皮肤科情况:右小腿胫前一黄豆大小半     

透明细胞棘皮瘤一例

透明细胞棘皮瘤是一种少见的表皮良性肿瘤,现遇１例,报告如下。患者男,５９岁。６月前发现有侧阴囊处有一绿豆大结节,缓慢长大,无自觉症状。体检：各系统检查无异常。皮肤科情况：右侧阴囊处可见直径０．８ｃｍ大暗红色结节,呈半球状隆起,边界清楚,表面少许脱屑,触之坚韧,无触痛。临床怀疑血管角皮瘤,手术切除治疗。切除标本组织病理检查：表皮轻度角化过度,棘层明显肥厚,皮突延长增宽。增生处表皮由大而透明的细胞组成,与两侧正常表皮分界明显。细胞胞浆丰富,呈透明状,细胞间桥清晰可见,并见较多中性粒细胞散布于增生的表…     

透明细胞棘皮瘤一例

34岁男性患者,右大腿出现无痛性结节1年余。皮肤科检查:右侧大腿前方可见一约绿豆大小红色圆顶丘疹,其上及其周边可见薄层细小鳞屑附着,无触痛。皮损组织病理示:角化过度伴角化不全,棘层增厚,表皮突延长,增生的棘细胞胞质淡染,与周围细胞分界清楚。诊断:透明细胞棘皮瘤。手术完整切除后随访半年无复发。     

透明细胞棘皮瘤一例报告

<正> 透明细胞棘皮瘤(clear cell acanthoma)是一种较少见的皮肤良性肿瘤,临床较易误诊。现将我们遇见的1例报告如下: 患者男,60岁。1984年左股部屈侧生一     

透明细胞棘皮瘤

组织病理特征图1的主要病理特征是表皮角化过度,角化不全,棘层肥厚,呈银屑病样增生;表皮突延长,部分融合,增生的表皮细胞胞质色淡,肿大呈多角形,与邻近正常角质形成细胞界限清楚,表皮内海绵水肿.     

透明细胞棘皮瘤

报告1例透明细胞棘皮瘤.患者女,72岁.左踝外侧约豌豆大的孤立性结节30余年伴痒2年.皮损组织病理检查:表皮内可见边界清楚的肿瘤组织,瘤细胞胞质透明、肿胀.诊断:透明细胞棘皮瘤.     

透明细胞棘皮瘤1例

报告1例透明细胞棘皮瘤。患者,女,38岁。左外踝上方结节5年余,破溃,结痂半年。患者组织病理检查显示：表皮轻度角化过度伴角化不全,棘层明显肥厚。肥厚的棘层内可见大量大而透明的细胞,胞浆丰富,胞质呈透明状,与两侧正常表皮分界清楚。细胞间可见大量中性粒细胞浸润,并形成munro微脓肿。真皮乳头内毛细血管扩张,血管周围可见以中性粒细胞为主的炎细胞浸润。肿瘤组织内可见大量汗管增生。结合临床和组织病理特点诊断为透明细胞棘皮瘤。     

透明细胞棘皮瘤1例

患者男,40岁。左足内侧两处褐色斑块10年余,门诊行手术切除,皮损组织病理示:角化不全,棘层肥厚,皮损部位细胞胞浆较透明,与正常角质细胞界限明显,PAS染色阳性,具有透明细胞棘皮瘤典型的病理表现。     

大细胞棘皮瘤一例

患者,男,62岁。右上肢斑块伴轻度瘙痒半年余。组织病理检查：网篮状角化过度,颗粒层细胞角质透明颗粒增多,各层细胞体积增大,可见轻度异型性,基底层色素增多,皮突延长,部分呈芽蕾状,与两侧正常表皮界限清楚,真皮浅层灶状单一核细胞浸润。诊断：大细胞棘皮瘤。行手术切除。     

Clear cell acanthoma

Clear cell acanthoma is a rarely diagnosed tumor with variable clinical morphology that is usually only recognized by its histopathological features. The primary lesion is a red papule a few millimeters in diameter that often occurs as a single lesion on the lower extremities. In dermoscopy, resemblance of the vessels to a string of pearls is a largely specific finding of clear cell acanthoma. In contrast to the initially uncharacteristic clinical findings, histopathology of clear cell acanthomas is characterized by a typical compact, well‐demarcated acanthosis consisting of pale‐staining, PAS‐reactive keratinocytes. As etiology and pathogenesis are both unclear, nosology of clear cell acanthoma is also controversial, with an ongoing debate as to its classification as cutaneous neoplasia or reactive inflammatory dermatosis.     

Clear cell acanthoma

Clear cell acanthoma (CCA), is an asymptomatic benign lesion of unknown origin and aetiology, which typically presents as a red to brown, dome‐shaped papule on the leg. We discuss the case of a patient with an irregular plaque of hypopigmented papules whose diagnosis of CCA was only made by biopsy, and review the characteristic presentation, uncommon variants, locations and associated conditions of this lesion. The diagnosis is based on histopathology and/or immunohistochemistry, but the variable clinical presentation may make diagnosis difficult. The differential diagnosis includes skin tumours and inflammatory and pigmentary dermatoses. The lesions do not regress spontaneously, and excisional removal is the preferred treatment.     

Polypoid clear cell acanthoma: case report

Clear cell acanthoma of Degos is a rare benign tumour of epidermal origin with distinct histological features. Clinically, clear cell acanthoma is characterized by a 'stuck on' appearance of a nodule or dome-shaped plaque that usually occurs on the legs of middle-aged or elderly persons. We observed an unusual case of polypoid clear cell acanthoma on the right thigh of a 58-year-old male.     

透明细胞鲍恩病

报告1例透明细胞鲍恩病.患者女,64岁.下腹部暗红色斑块、结痂伴瘙痒10年.皮肤科检查:下腹部见一4 cm×5 cm不规则暗红色斑,稍高出皮面,表面有黑褐色痂.皮损组织病理检查示:表皮角化过度伴角化不全,棘层增生肥厚,其中可见核大浓染的细胞、角化不良细胞及核分裂象,棘层上部细胞胞质丰富淡染透亮.诊断:透明细胞鲍恩病.