眼上静脉入路Onyx联合弹簧圈填塞海绵窦治疗海绵窦区硬脑膜动静脉瘘

海绵窦区硬脑膜动静脉瘘(dural arteriovenous fistula,DAVF)临床表现以眼部症状多见,表现为受累侧突眼、球结膜充血、视力下降和复视等症状,首选治疗方法为经静脉入路血管内介入.治疗的关键在于采用各种栓塞材料填塞海绵窦处的瘘口,以彻底消除病变.我们采用眶上内侧缘切开眼上静脉置管后,血管内填塞弹簧圈和液体栓塞剂Onyx,治愈l例海绵窦区DAVF患者,现报道如下.     

静脉入路栓塞治疗海绵窦区硬脑膜动静脉瘘临床分析

目的综合性的比较静脉入路联合液体胶和弹簧圈介入栓塞海绵窦区硬脑膜动静脉瘘[1](CSDAVF)与可脱弹簧圈栓塞治疗CSDAVF的优缺点,确定治疗该病的最佳方案。方法回顾性的分析我院随访的20例2007～2011年期间进行静脉入路栓塞治疗海绵窦区硬脑膜动静脉瘘的患者,其中经静脉入路联合液体胶和弹簧圈介入栓塞海绵窦区治疗CSDAVF者13例,设为A组;经可脱弹簧圈栓寒治疗CSDAVF者7例设为B组。将两组的治疗结果进行比较分析。结果 A组治愈13例,治疗费用(10.5±3.4)万元,B组治愈5例,2例好转治疗费用(17.1±3.8)万元。结论静脉入路联合液体胶和弹簧圈介入栓塞海绵窦区硬脑膜动静脉瘘为理想的治疗方法。     

经静脉入路采用Onyx联合弹簧圈栓塞治疗海绵窦区硬脑膜动静脉瘘疗效分析

目的探讨经静脉入路Onyx联合弹簧圈栓塞治疗海绵窦区硬脑膜动静脉瘘(CDAVF)的疗效。方法 8例CDAVF患者均经静脉入路用Onyx联合弹簧圈栓塞治疗,通过术后造影和临床随访来评估临床效果。结果 8例栓塞后即刻造影检查示瘘口及海绵窦完全闭塞6例,少量残留2例,总有效率为100%,治愈率为75%。栓塞后1例出现动眼神经麻痹,经对症治疗后痊愈,无其他严重并发症发生。术后所有患者均接受临床随访,随访时间3个月至2年,无症状复发及加重者。结论经静脉入路Onyx联合弹簧圈栓塞治疗CDAVF是一种安全及有效的方法。     

经眼上静脉栓治疗自发性海绵窦硬膜动静脉瘘9例报告

采用经眼上静脉途径栓塞治疗自发性海绵窦膜动静脉瘘６例导管可直接插入海绵窦（ＧＳ）推入栓塞材料。２个月后９例症状全部消失,则颈内动脉供血。     

海绵窦区硬脑膜动静脉瘘的栓塞治疗

目的　探讨海绵窦区硬脑膜动静脉瘘的治疗方法。方法　海绵窦区硬脑膜动静脉瘘共 12例 ,经颈外动脉以微粒栓塞 3例 ;以正丁基氰基丙烯酸异丁酯 (NBCA)栓塞 2例 ;经颈外动脉插入海绵窦以NBCA栓塞1例 ;经岩下窦以机械可脱性弹簧圈 (MDS)栓塞 1例 ;经眼上静脉以MDS栓塞 5例。结果　瘘口完全消失 8例 ;瘘口残留 4例 ,其中 2例瘘口残留患者 3个月后症状好转。结论　根据不同的类型 ,经静脉栓塞和经动脉栓塞均可作为海绵窦区硬脑膜动静脉瘘的有效治疗方法     

多静脉途径介入栓塞海绵窦区硬脑膜动静脉瘘

目的探讨多静脉途径介入栓塞海绵窦区硬脑膜动静脉瘘的方法、策略和疗效。方法27例海绵窦区硬脑膜动静脉瘘患者,分别经岩下窦、面静脉和眼上静脉等静脉途径介入栓塞治疗。结果23例临床治愈,4例症状明显缓解。术后即刻造影提示22例瘘口完全消失,5例虽将海绵窦致密填塞,但其中2例仍有少量翼丛引流,1例通过海绵间窦向对侧引流,2例存在少量岩上窦后引流,压颈1个月后消失。栓塞术后并发症主要表现为头痛和呕吐,3例出现轻度复视,后自行恢复;无1例出现永久性介入相关并发症。临床随访5个月～6年,患者无临床症状复发。结论多静脉途径介入栓塞是治疗海绵窦区硬脑膜动静脉瘘安全、有效的方法。     

经眼上静脉、颈外动脉联合入路治疗海绵窦区硬脑膜动静脉瘘1例报告

患者 ,男 ,32岁。因“左侧突眼伴视力下降 ,颅内杂音 2年半”入院。患者曾 2次在外院行ＤＳＡ全脑血管造影 ,诊断为左侧海绵窦区硬脑膜动静脉瘘 (ｃａｒｖｅｒｎｏｕｓｄｕｒａｌａｒｔｅｒｉｏｖｅｎｏｕｓｆｉｓ ｔｕｌａ ,ＣＤＡＶＦ) ,行经颈外动脉血管内栓塞治疗 ,症状均无缓解。入院时查体 ;左侧眼球向外突出。左眼球结膜、睑结膜中度充血。左眼上静脉明显扩张 ,可扪及搏动。粗测双眼视野正常。视力左眼 0 .1、右眼 1.2。左眼底视乳头水肿 ,Ａ/Ｖ =1/ 4。左眼眶上听诊可闻及血管杂音 ,压迫左颈总动脉后杂音消失。ＴＣＤ检查 :颈部血管…     

海绵窦区硬脑膜动静脉瘘的栓塞治疗

目的：探讨海绵窦区硬脑膜动静脉瘘的病因及诊治方法。方法：21例均采用超选择插管栓塞，其中4例同时静脉入路微弹簧圈海绵窦内栓塞。结果：17例瘘口完全消失；4例栓塞后瘘口有残留，结合颈动脉压迫法治疗后2例瘘口消失。结论：血管内栓塞治疗海绵窦区硬脑膜动脉瘘是目前行之有效的方法。     

海绵窦区硬脑膜动静脉瘘影像学表现与栓塞治疗

海绵窦区硬脑膜动静脉畸形瘘（dural arterioveous fistula，DAVF）是指海绵窦区及其附近硬脑膜动静脉之间的异常交通，属脑血管畸形的一种，其临床表现、影像学表现及治疗均有其特点。本文报告13例DAVF病例的临床与影像学资料，并结合文献作一回顾性分析。     

动脉入路ONYX栓塞治疗海绵窦区硬脑膜动静脉瘘的临床观察

目的探讨采用单纯动脉入路ONYX(医用胶)治疗在海绵窦区硬脑膜海绵窦瘘的意义及栓塞程度对预后的影响。方法回顾性分析2008—2010年我院行动脉入路ONYX治疗的10例患者的手术方式、术中栓塞程度、随访结果及临床意义,10例患者病变均为外伤性,均为择期手术,术中成功弥散ONYX胶,栓塞程度不同,术后随访至1年。结果 3例患者术后残留,行2期治疗,有7例ONYX胶弥散满意,术中造影无残留,分别于随访6个月、1年,3例残留者,瘘口较前分流增多,行2期治疗后,无残留。结论采用经动脉途径予以栓塞治疗的疗效已不容置疑,其优点在于:①可避免经静脉途径栓塞,正常静脉被误栓及栓塞后导致的出血。②术中观察,造影方便,射线量少。③动脉入路操作方便,适用于大多数患者,通过ONYX良好的弥散性能达到完全闭塞瘘口的目的而又不影响血液经静脉窦的正常回流,因此一般可以作为首选。     

Therapeutic embolization of cavernous sinus dural arteriovenous fistulas via transvenous approach

Cavernoussinusduralarteriovenousfistulas (CSdAVFs)formacomplexcommunicationnetworkbetweenthecavernoussinus (CS)andtheduralbranchesoftheexternalcarotidartery (ECA)and/orinternalcarotidartery (ICA) CSdAVFsusuallybecomesymptomaticspontaneouslyandoccurmostofteninelderlywomen TheclinicalmanifestationsofCSdAVFsdependonthepatternofvenousdrainage Chemosis ,conjunctivalcongestion ,bruit,ophthalmoplegia ,eyelidswelling ,proptosis,diplopia ,andvisualacuityimpairmentmayallresultfromCSdAVFs 1 …     

Transvenous embolization with a combination of detachable coils and Onyx for a complicated cavernous dural arteriovenous fistula

Background Treatment of cavernous dural arteriovenous fistulas （DAVF） is usually made by a transarterial approach. However, in many complicated patients, treatments via transarterial approaches can not be achieved, and only an operation via a transvenous approach is feasible. We aimed to study the feasibility of transarterial embolization of cavernous dural arteriovenous fistulas with a combination detachable coils and Onyx to embolize a complicated cavernous DAVF via a transvenous approach. Methods From August 2006 to August 2007, six cases of complicated cavernous DAVF were embolized with a combination of detachable coils and Onyx via a transvenous approach. Three cases were male and the other three were female. Their ages ranged from 36 to 69 years old. The fistula was in the right lateral cavernous sinus in one case, in the left lateral cavernous sinus in another, and in the bilateral cavernous sinus in 4 cases. One fistula was fed by the right internal carotid artery and its meningohypophyseal trunk; one was fed by the branches of the left internal carotid artery and left external carotid artery; four were fed by the branches of the bilateral internal carotid artery and/or the bilateral external carotid artery. One case was drained via one lateral inferior petrosal sinus; three were drained via bilateral inferior petrosal sinuses; one was drained via one lateral ophthalmic and facial veins; one was drained via the inferior petrosal sinus and the ophthalmic and facial veins. Four were embolized via the inferior petrosal sinus, and two were embolized via the ophthalmic and facial veins. Results Among six cases of complicated cavernous DAVF, four were fully embolized with Onyx by a single operation, and two cases were fully embolized with Onyx following two operations. Transient headache was found after operation in all patients, but was cured after several days by the symptomatic treatments. In one case, the first operation via the inferior petrosal sinus was a failure; the feeding branches of the external     

Therapeutic embolization of cavernous sinus dural arteriovenous fistulas via

Objective To describe the transvenous catheterization technique for the treatment of cavernous sinus dural arteriovenous fistulas (CSdAVFs), including its indications, complications and efficacy.Methods Eight patients with symptomatic CSdAVFs were treated by endovascular embolization with platinum coils, via the inferior petrosal sinus (IPS) in 6 patients, and via the Sylvian vein after surgical exposure in other 2 patients.Results Complete angiographic resolution of the fistula was obtained in six patients immediately after the procedures, and a complete resolution of symptoms and signs was achieved in all patients. The residual fistulas in two patients disappeared completely in the follow-up angiography.Conclusion Transvenous embolization is a useful and safe approach in the management of CSdAVFs.     

Transarterial Onyx embolization of intracranial dural arteriovenous fistulas: A single center experience

BackgroundTransarterial embolization of intracranial dural arteriovenous fistulas (DAVFs) is usually associated with inadequate embolization. The purpose of this study was to report our experience of transarterial Onyx embolization of intracranial DAVFs with an emphasis on treatment outcome with this new embolic agent in different types of DAVFs.MethodsIn the past 3 years, a total of 14 intracranial DAVFs have been treated by transarterial Onyx embolization. Among these, there were nine males and five females, aged from 30 years to 82 years (mean = 62 years). We retrospectively analyzed the injection volume and time of Onyx embolization as well as outcomes in different types of DAVFs.ResultsThe locations of the DAVFs were sigmoid sinus (n = 6), tentorium (n = 3), sinus confluence (n = 2), transverse–sigmoid sinus (n = 1), sigmoid sinus–jugular bulb (n = 1) and the superior petrous sinus (n = 1). The mean volume and time of Onyx injection were 3.4 mL and 28 minutes, respectively (Cognard type I: 4.9 mL, 40 minutes; type II: 4.5 mL, 34 minutes; type III: 2.2 mL, 21 minutes; type IV: 2 mL, 22 minutes). Total fistula occlusion was achieved in six out of seven patients of type III and type IV DAVFs, and in four out of seven patients of type I and type II DAVFs. Nine patients had total resolution of their symptoms, whereas partial regression occurred in five patients. No significant periprocedural complication was found. Mean clinical follow-up period was 16 months.ConclusionTransarterial Onyx embolization of intracranial DAVFs is safe and effective. This technique is particularly useful in type III and type IV DAVFs with a high cure rate, and lower volume of Onyx as well as a short injection time.     

非粘附性栓塞材料Onyx栓塞治疗脑动静脉畸形疗效的临床研究

目的:探讨用新型非粘附性液体栓塞材料Onyx(美国MTI公司产)栓塞脑动静脉畸形(arteri-ovenous malformation,AVM)的疗效。方法:2003年9月至2004年9月用微导管技术应用Onyx胶栓塞22例脑动静脉畸形。畸形团的位置:10例位于大脑重要功能区,8例位于大脑深部组织区,4例位于小脑半球。畸形团的直径:<3 cm 5例,3~6 cm 11例,>6 cm 6例。结果:22例脑动静脉畸形得到有效栓塞。其中,3例畸形团从影像上完全消失,8例90%以上消失,6例80%~90%消失,5例消失在80%以下。栓塞术后并发症少见,2例有短暂神经功能障碍,2例微导管头端粘附于畸形团内,无法撤出,微导管被留置于大血管内。结论:由于Onyx良好的非粘附性,可以向畸形团内注入更多的量,故在栓塞脑动静脉畸形是安全、有效的。     

海绵窦区硬脑膜动静脉瘘的治疗探讨

目的 探讨海绵窦区硬脑膜动静脉瘘(dural arteriovenous fistula,DAVF)的治疗方法、效果及预后.方法 25例患者中8例行颈动脉压迫或仅随访观察;17例行血管内栓塞,其中3例经静脉途径栓塞,13例经动脉途径栓塞,其中1例联合使用覆膜支架和Glubran胶治疗,1例经动脉途径治疗后再次接受经静脉途径栓塞治疗.结果 8例行颈动脉压迫或随访观察的患者中有4例症状缓解或消失,其余患者无加重;3例经静脉途径栓塞者均通过同侧或对侧岩下窦入路完全闭塞瘘口;13例经动脉途径栓塞者中4例完全闭塞瘘口,其余患者症状部分缓解;1例患者首次经动脉途径部分栓塞术后症状加重,急诊经眼上静脉穿刺置管完全栓塞.结论 海绵窦区DAVF总体预后良好,可根据患者症状和影像学特征选择恰当的治疗方式,经静脉途径栓塞治愈率高,适宜者应作为首选治疗方法.     

Transvenous injection of n-Butyl cyanoacrylate combined with placement of coils in cavernous sinus for treatment of cavernous dural arteriovenous fistulae

Objective： To evaluate the technical aspects, efficacy and safety in the treatment of cavernous dural arteriovenous fistulae （DAVF） by transvenous liquid n-Butyl cyanoacrylate （NBCA） injection combined with coils placement in the cavemous sinus. Methods： Eight patients with cavernous DAVF, treated by transvenous embolization with combination of detachable coils and glue between February 2006 and February 2009 in our hospital, were retrospectively analyzed, including the clinical presentations, patterns of angioarchitecture, methods of treatment and the results of follow-up. Results： In all 8 patients, 9 transvenous and 1 transarterial interventions were carried out. A single endovascular procedure was performed in 6 patients and 2 patients had to be treated twice. Of the nine transvenous approaches, eight approaches were performed via inferior petrosal sinus （IPS） and 1 via the facial vein. Complete angiographic obliteration was achieved in all patients immediately after the embolization. There was no procedure-related morbidity except for mild headache for one to seven days after the embolization. Clinical cure was achieved in all cases during the clinical follow-up periods, ranging from 8 months to 3 years. The follow-up angiography periods averaged 6.6 months with a range of 5-9 months, in which no recurrence was observed. Conclusion： In this small series, embolization with combination of glue and detachable coils by transvenous approaches was a safe, effective and economical method for the treatment of part of symptomatic patients presenting with complex cavernous DAVE