替牙期骨性Ⅲ类患者上前牙牙槽骨形态及其影响因素

目的 评估替牙期骨性Ⅲ类患者上前牙区牙槽骨形态，并探讨其影响因素。方法 选取替牙期骨性Ⅲ类患者48例，基于治疗前的锥体束CT(CBCT)，测量上颌中切牙和侧切牙唇舌侧的牙槽骨厚度和高度，测量牙齿长度、前牙倾斜度、下颌平面角。结果 上颌中切牙舌侧牙槽骨厚度为(3.34±1.33)mm，上颌中切牙唇侧牙槽骨厚度为(1.24±0.51)mm，上颌中切牙舌侧牙槽嵴顶距釉牙骨质距离(1.30±0.89)mm，上颌侧切牙唇侧牙槽嵴顶距釉牙骨质距离(1.68±0.88)mm。上中切牙舌侧牙槽骨厚度、唇侧牙槽骨高度与切牙唇倾度负相关，上切牙唇侧牙槽骨厚度与牙齿长度和下颌平面角负相关。结论 替牙期骨性Ⅲ类患者上切牙唇侧牙槽骨较薄，附着高度较低，舌侧牙槽骨较厚、附着高度较高。上切牙牙槽骨形态与切牙唇倾度、牙齿长度、下颌平面角均有相关性。     

牙槽突裂植骨术后植入骨的定位分析

目的应用牙CT对牙槽突裂植骨术后的骨桥位置进行定位分析。方法选取18名单侧完全性牙槽突裂患者,在牙槽突裂植骨术后3个月对植骨部位进行牙三维CT扫描,将牙槽突裂隙分割后对植入骨进行定位。结果牙槽突裂植骨术后,近远中向上骨桥的数量没有统计学差异（P>0.05）;唇腭向上唇侧的骨桥数多于腭侧骨桥数（P<0.001）;垂直向上,植入骨的骨桥主要存在于裂隙侧中切牙的根中和根尖1/3,而鼻底及近牙槽嵴顶的骨桥数量较少（P<0.05）。结论牙槽突裂植骨术后骨桥的位置主要位于裂隙侧中切牙的根中和根尖1/3处,且唇侧的骨量明显多于腭侧的骨量。     

单侧完全性唇腭裂伴牙槽嵴裂患者植骨术后尖牙的牵引助萌

单侧完全性唇腭裂患者常伴有牙槽嵴裂,而裂隙侧的尖牙多发生阻生,即使在适当的年龄做了牙槽嵴植骨术,也常会出现尖牙阻生。本文介绍一例单侧完全性唇腭裂伴牙槽嵴裂患者经过术前扩弓治疗后进行牙槽突裂植骨,植骨术后正畸治疗完成尖牙牵引助萌。     

应用锥形束CT探究上颌前牙区颌骨微种植支抗钉植入的安全区

目的:对上颌前牙区颌骨的骨量及唇侧骨皮质厚度进行测量分析,为正畸治疗植入微种植支抗钉的安全区提供参考。方法:对25例成人患者上颌前牙区行锥形束CT扫描及三维重建,测量距上颌牙槽嵴顶3、6、9、12 mm水平上颌中切牙、侧切牙、尖牙根间区近远中向、唇腭向的距离以及唇侧骨皮质厚度。结果:在距上颌牙槽嵴顶3、6、9 mm水平中切牙根间近远中向距离均最宽,唇侧骨皮质均最薄;在距牙槽嵴顶9mm水平中切牙与侧切牙根间近远中向距离最窄;在4个测量水平侧切牙与尖牙根间唇侧骨皮质均最厚;唇腭向在距牙槽嵴顶9 mm及以上水平,中切牙根间骨厚度最薄,中切牙与侧切牙根间骨厚度最厚。25例中仅3例前牙区各牙根长度超过12 mm,在距牙槽嵴顶12 mm水平测出的根间近远中向距离均较宽。结论:通过对扫描后颌骨影像的分析,明确了前牙区颌骨的骨量及唇侧骨皮质厚度,为植入微种植支抗钉的安全区提供参考。     

正常人外鼻缺损种植区域三维测量

目的:为外鼻缺损的种植体植入提供影像解剖学资料.方法:使用mimics10.01软件对100 例正常人(男性50 例,女性50 例)头颅螺旋CT三维重建影像进行测量.结果:(1)中切牙根尖至前鼻底最小距离均值为13.03 mm(男),11.06 mm(女),侧切牙根尖至前鼻底最小距离均值为15.95 mm(男),13.04 mm(女);(2)侧切牙区上颌骨腭突最小厚度均值为9.96 mm;(3)中切牙区牙槽突上方最小骨厚度均值为11.12 mm,侧切牙区牙槽突上方最小骨厚度均值为11.24 mm;(4)眉间点位于窦腔部位时骨厚度均值为3.57 mm.结论:前鼻底侧切牙区域为较佳种植区,常规可纵向植入2 枚长度4～8 mm种植体,种植方向可根据需要选择向前倾斜或者向后倾斜;当纵向骨量不足时,可选择于侧切牙区域横向植入2 枚长度4～8 mm的种植体;眉间点作为种植体植入部位应慎重.     

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目的对上颌前牙区颌骨的骨量及唇侧骨皮质厚度进行测量分析,为正畸治疗植入微种植支抗钉的安全区提供参考依据。方法对2010年9月至2011年6月来大连市口腔医院就诊的25例成人患者行锥形束CT扫描及三维重建,测量距上颌牙槽嵴顶3、6、9、12mm4个水平上颌中切牙、侧切牙、尖牙根间区近远中向、唇腭向的距离以及唇侧骨皮质厚度。结果 (1)在距上颌牙槽嵴顶3、6、9mm水平中切牙根间近远中向距离均最宽,唇侧骨皮质均最薄;(2)在距牙槽嵴顶9mm水平中切牙与侧切牙根间近远中向距离最窄;(3)在4个测量水平侧切牙与尖牙根间唇侧骨皮质均最厚;(4)唇腭向在距牙槽嵴顶9mm及以上水平,中切牙根间骨厚度最薄,中切牙与侧切牙根间骨厚度最厚。25例中仅3例前牙区各牙根长度超过12mm,在距牙槽嵴顶12mm水平能测出根间近远中向距离,均较宽。结论通过对扫描后颌骨影像的分析,明确了前牙区颌骨的骨量及唇侧骨皮质厚度,为植入微种植支抗钉的安全区提供参考依据。     

三种矫治器治疗安氏Ⅱ类2分类对切牙牙根吸收的影响

目的 比较不同矫治器治疗安氏Ⅱ类2分类错牙合畸形患者切牙牙根的吸收状况。方法 选择使用不同矫治器的安氏Ⅱ类2分类成年患者30例,其中传统MBT托槽、自锁托槽以及无托槽隐形矫治器的患者各10例,共计240颗切牙。收集患者治疗前后的锥形束CT(CBCT)影像学资料,并导入Dolphin Imaging软件,Mimics软件以及3-Matics软件测量分析治疗前后切牙牙根吸收情况。结果 传统MBT托槽组和自锁托槽组的上下颌中切牙以及侧切牙的牙齿长度(L)与无托槽隐形矫治器组上下颌中切牙及上颌侧切牙的牙齿长度治疗后较治疗前显著减小,差异具有统计学意义。使用无托槽隐形矫治器的患者下颌侧切牙治疗前后的牙齿长度无显著变化。而三组之间的对比,上下颌中切牙牙齿长度变化无显著统计学差异。无托槽隐形矫治器组上下颌侧切牙的牙齿长度减少量相对更低,差异具有统计学意义(P＜0.05)。此外,无托槽隐形矫治器组平均牙齿长度变化为(-0.37±0.11)mm,显著小于传统MBT托槽组(-1.32±0.47)mm及自锁托槽组(-1.05±0.38)mm。在牙根吸收区域的比较上,各组均表现为腭侧吸收多于唇侧吸收,近中吸收多于远中吸收。结论 无托槽隐形矫治器治疗安氏Ⅱ类2分类错牙合畸形可有效降低切牙牙根吸收严重程度。     

齿槽嵴裂植骨术后植入骨位置的临床评价

目的应用牙三维成像(CBCT)对齿槽嵴裂植骨术后的植入骨位置进行临床评价。方法选取18名单侧完全性齿槽嵴裂患者,在齿槽嵴裂植骨术后3个月对植骨部位进行CBCT扫描,将齿槽嵴裂隙分割后对植入骨的位置进行定位。结果齿槽嵴裂植骨术后,近远中向上植入骨的数量没有统计学差异(P>0.05);唇腭向上唇侧的植入骨数多于腭侧植入骨数(P<0.001);垂直向上,植入骨主要存在于裂隙侧中切牙的根中和根尖1/3,而鼻底及近牙槽嵴顶的植入骨数量较少(P<0.05)。结论齿槽嵴裂植骨术后植入骨的位置主要位于裂隙侧中切牙的根中和根尖1/3处,且唇侧的骨量明显多于腭侧的骨量。     

单侧完全性唇腭裂患者鼻上颌复合体对称性的三维分析

目的 三维分析成年期前未行腭裂修复术的单侧完全性唇腭裂（UCLP）患者的鼻上颌复合体形态对称性.方法 对9例2.5岁前完成唇裂修复术、成年前未行腭裂修复术的UCLP患者进行螺旋CT扫描、三维重建,选择22个头颅标志点进行定点测量,分析鼻上颌复合体的三维形态.结果 成年前未行腭裂修复术UCLP患者裂侧NC-HP、PF-MSP距离分别为18.01mm、19.72mm,大于健侧13.35mm、17.31mm（P＜0.05）;裂侧NC-CP、U3-HP距离分别为59.64mm、39.55mm,小于健侧64.13mm、39.70mm（P＜0.05）,即裂侧鼻腔较健侧明显下凹和塌陷,裂侧后段硬腭宽度大于健侧,尖牙低位.正中结构存在偏移,鸡冠点、鼻中隔、上中切牙中点偏向裂侧,骨性前鼻棘点朝向健侧.结论 成年前未行腭裂修复术的UCLP患者颅面不对称主要集中在鼻腔和邻近裂隙的牙齿槽区,颅面上部和远离裂区的区域没有明显不对称.     

阻生尖牙牵引治疗前后上颌切牙牙根外吸收的锥形束CT分析

目的通过锥形束CT测量探讨阻生尖牙牵引治疗前后上颌切牙牙根外吸收的变化。方法选取2011年7月至2019年1月于南京医科大学附属口腔医院正畸科就诊的上颌尖牙阻生致切牙牙根外吸收的患者24例, 年龄(12.3±1.6)岁(10～14岁), 其中男性11例, 女性14例。将治疗前牙根发生外吸收的上颌切牙纳入吸收组(中切牙21颗, 侧切牙22颗), 以牙根未发生外吸收的同名上颌切牙为对照组(中切牙26颗, 侧切牙21颗)。对正畸治疗全部完成满1年的患者进行随访并拍摄锥形束CT, 随访到患者15例, 其中吸收组中切牙10颗、侧切牙12颗, 对照组中切牙16颗、侧切牙12颗。测量分析上颌切牙在牵引前(治疗前)、牵引后(阻生尖牙牵引到位时)及随访时(正畸治疗全部完成后1年)的牙根长度及牙体体积, 同时分析尖牙牵引期间(牵引前-牵引后)及随访期间(牵引后-随访时)牙根长度及牙体体积的变化量。结果牵引后吸收组和对照组中切牙和侧切牙牙根长度及牙体体积均显著小于同组牵引前(P<0.05)。除吸收组侧切牙牙体体积外, 随访时吸收组和对照组切牙牙根长度及牙体体积均显著小于同组牵引后(P<0.05)...     

Mesiodistal size of deciduous teeth in subjects with unilateral cleft lip and palate

The aim of this study was to investigate whether there was an association between presence of a cleft and reduced size of deciduous tooth on the cleft side. In this investigation, 58 study models of patients with unilateral cleft lip and palate with deciduous dentition were analyzed. The largest mesiodistal dimension of deciduous teeth was measured by a sliding caliper. The size of the same teeth on the side of the cleft and on the non-cleft side was compared. The results of the investigation were statistically analyzed. A difference between the genders was found. In the sample of boys the lateral deciduous incisor and the second deciduous molars on the cleft side were smaller than those on the non-cleft side, while in girls the central and lateral deciduous incisors were smaller on the cleft side than on the non-cleft side. It was concluded that the presence of a unilateral cleft lip and palate was associated with smaller tooth size.     

Emergence of the deciduous incisors in CLP children

A longitudinal study of the time of emergence of the deciduous incisors was performed in Dutch cleft lip and/or palate (CLP) children (n = 52). A group of normal children (n = 62) served as control. Emergence dates were registered by the parents and checked regularly by one of the investigators. Mean emergence times of the deciduous upper incisors--including both the cleft-sided lateral in the distal segment and in the premaxilla--and lower incisors were studied. The lateral incisor on the cleft side situated in the distal segment was delayed 8 months in children with a cleft lip and alveolus and 13 months in cleft lip and palate children. The delay for the lateral incisor situated in the premaxilla increased by nearly 4 months in these children. The upper lateral incisors on the non-cleft side and in cleft palate children were not delayed as compared with normal children. The central lower incisors emerged one month earlier than normal when there was a palatal cleft. Presurgical orthopaedics used in these groups could have caused this acceleration. The central upper and lateral lower incisors showed no significant differences in mean emergence ages as compared with the control group, nor between the various cleft types. Sex differences were not found in any of the groups.     

Mesiodistal tooth size in non-syndromic unilateral cleft lip and palate patients: a meta-analysis

Objectives

To evaluate, using meta-analysis methodology, mesiodistal tooth dimensions in non-syndromic unilateral cleft lip and palate (CLP) patients.

Materials and methods

A literature search was conducted using PubMed, Medline, Google Scholar Beta, EMBASE Excerpta Medica, CINAHL, Web of Science, and the Cochrane Collaboration, identifying English and non-English articles reporting on mesiodistal tooth dimensions on the cleft and non-cleft side of non-syndromic unilateral CLP patients. Additional studies were identified by searching reference lists of articles consulted. Only studies with a suitable control group were included. Two examiners independently performed the literature search and data extraction. Using meta-analysis software, data extracted from each selected study were statistically combined using the fixed-effects model. Weighted mean differences, 95 % confidence intervals, and heterogeneity were calculated for each measurement.

Results

Four articles fulfilling the inclusion criteria were located and included in the meta-analysis. Maxillary incisors and first molars were found to be significantly larger on the non-cleft side while mandibular incisors and premolars were larger on the cleft side, in non-syndromic unilateral CLP patients. On the cleft side, maxillary premolars and second molars were larger in cleft than control patients while incisors were smaller, whereas all mandibular teeth were larger in cleft patients. On the non-cleft side, all maxillary teeth except for the central incisors were larger in the cleft than control patients, while all mandibular teeth were larger in the cleft patients except for lateral incisors.

Conclusions

Non-syndromic unilateral CLP patients tend to have larger posterior but smaller anterior teeth compared with the general population. Comparing sides, unilateral CLP patients tend to have smaller maxillary but larger mandibular teeth on the cleft than on the non-cleft side.

Clinical relevance

Given that obtaining a stable, functional, and esthetic occlusion requires a thorough evaluation of tooth size, knowledge about trends in tooth size variations in CLP patients can help with dental and orthodontic treatment planning.     

Comparison of tooth development stage of the maxillary anterior teeth before and after secondary alveolar bone graft: Unilateral cleft lip and alveolus vs unilateral cleft lip and palate

Objective:To compare the effect of secondary alveolar bone graft (SABG) on the tooth development stage of the maxillary central incisor (MXCI) and maxillary canine (MXC) in terms of the severity of unilateral cleft.Materials and Methods:The subjects consisted of 50 boys with unilateral cleft lip and alveolus (UCLA) or unilateral cleft lip, alveolus, and palate (UCLP). The age- and sex-matched subjects were divided into group 1 (UCLA, n = 25; 9.3 ± 0.8 years old) and group 2 (UCLP, n = 25; 9.4 ± 0.6 years old). In panoramic radiographs taken 1 month before (T0) and 1 year after SABG (T1), tooth development stage was evaluated according to the Nolla developmental (ND) stage. A panoramic radiograph taken 3 years after SABG was used as a reference for the final root length of individual tooth.Results:In groups 1 and 2, the ND stage of the MXCI did not exhibit differences between the cleft and non-cleft sides at T0 and T1, respectively. However, although the ND stage of the MXC of group 2 was delayed on the cleft side compared with the non-cleft side at T0 (P < .05), the MXC on the cleft side developed faster than that on the non-cleft side after SABG (P < .01). In terms of tooth development speed, group 2 showed a higher rate of faster developed MXCs on the cleft side compared with the non-cleft side after SABG than group 1 (36.0% vs 8.0%, P < .05).Conclusion:SABG performed at approximately 9 years of age might increase tooth development speed of MXC in patients with UCLP compared with patients with UCLA.     

唇腭裂患者上颌前部牙槽骨厚度及骨开窗、骨开裂的三维评价研究

目的　利用锥形束CT（cone-beam CT,CBCT）评价不同类型唇腭裂患者上颌前部牙槽骨厚度和形态,以及上前牙骨开窗、骨开裂情况。方法　选择016年8月至019年10月间在南京医科大学附属口腔医院就诊拟行口腔正畸治疗的唇腭裂患者85例（男51例,女34例,平均年龄（14.65±4.95）岁）,其中单侧唇裂伴牙槽突裂（unilateral cleft lip and alveolus,UCLA）患者19例,单侧完全性唇腭裂（unilateral complete cleft lip and palate,UCLP）患者5例,双侧完全性唇腭裂（bilateral complete cleft lip and palate,BCLP）患者14例。在正畸治疗开始前均予以拍摄颌面部CBCT,应用Image J软件测量其上前牙唇腭侧牙槽骨厚度（alveolar bone thickness,ABT）,计算骨开窗、骨开裂发生率,并比较不同唇腭裂类型患者上颌前部ABT及上前牙骨开窗、骨开裂发生率的差异。结果　UCLP、UCLA患侧上前牙骨开裂发生率（34.9%、4.9%）显著高于其健侧（10.7%、11.1%）,但骨开窗发生率无统计学差异。UCLP健侧上中切牙（5.9%）、侧切牙（9.7%）骨开裂发生率低于UCLA。UCLA、UCLP、BCLP三组间患侧上前牙骨开裂及骨开窗发生率均无统计学差异。UCLP、UCLA患侧上前牙ABT在多部位小于其健侧。除UCLP/UCLA患侧侧切牙外,UCLA、UCLP、BCLP各类型上前牙唇侧平均ABT均小于腭侧。UCLA、UCLP、BCLP三组间患侧上前牙唇腭侧平均ABT无统计学差异。UCLP患侧上侧切牙、尖牙分别在唇侧和腭侧根颈处ABT大于UCLA。结论　单侧唇腭裂患者患侧上前牙骨开裂发生率高于健侧,ABT则在多部位小于其健侧;而三种类型患者上前牙唇侧ABT均小于其腭侧。单侧唇裂伴牙槽突裂与单侧完全性唇腭裂患者健侧上中切牙、侧切牙骨开裂发生率及患侧侧切牙、尖牙根颈处牙槽骨厚度存在差异;单侧与双侧完全性唇腭裂间上前牙骨开窗、骨开裂发生率及牙槽骨厚度则无差异。     

替牙期骨性Ⅲ类单侧完全性唇腭裂患者修复术后口周力的分布特征

目的:通过与同龄非唇腭裂正常 儿童比较,研究替牙期骨性Ⅲ类单侧完全性唇腭裂(unilateral cleft lip and palate,UCLP)患者上下颌不同位点口周力的特征。 方法:选取替牙期6～12岁UCLP患者20例(男14例,女6例)为UCLP组;同龄正常 儿童21例(男14例,女7例)为对照组。采用口周肌压力采集系统测量每个研究对象息止 位时双侧上下颌中切牙、尖牙或乳尖牙、第一前磨牙或乳磨牙、第一恒磨牙的唇颊、舌腭侧龈缘的口周力。使用SPSS 25.0统计软件对数据进行统计分析。 结果:1．UCLP组上颌口周力裂侧大于非裂侧( P<0.05),下颌口周力两侧无差异( P>0.05)。2. UCLP组上颌口周力大于对照组( P<0.05),两组上颌唇颊侧的口周力均在第一前磨牙/乳磨牙区最大,在中切牙区最小。3. UCLP组下颌唇颊侧口周力小于对照组( P<0.01),下颌中切牙舌侧区UCLP组大于对照组( P<0.05)。4. UCLP组上颌牙弓内外口周力差值大于对照组( P<0.05),下颌差值小于对照组( P<0.01)。 结论:替牙期骨性Ⅲ类UCLP患者口周力较同龄非唇腭裂正常 儿童存在异常。     

Vertical Changes in Patients with Complete Unilateral and Bilateral Cleft Lip, Alveolus and Palate

AIMS AND METHODS: Twelve UCLP and eleven BCLP patients who had been treated according to the Hanover treatment protocol were evaluated by means of cephalometric analysis and cast measurements. The aim of this investigation was to demonstrate changes in the vertical plane and in incisor position in the course of craniofacial growth compared to age-matched non-cleft controls. Lateral cephalograms and casts were analyzed for each cleft patient at age 10 and 15 and compared with corresponding data of a non-cleft control group (n = 20). RESULTS: A vertical growth impairment of the maxilla was registered in patients with cleft lip, alveolus and palate. The maxilla of the cleft patients showed a significant clockwise rotation while the inclination of the mandible remained virtually unchanged. Both upper and lower incisors, which were significantly retruded at the beginning of the late mixed dentition, could be protruded in the course of craniofacial growth, development of the dentition and treatment, but remained retruded in comparison with the non-cleft controls. The posterior midfacial height was highly significantly shorter in both UCLP and BCLP patients at both evaluation timepoints, whereas the anterior lower jaw height was greater than in the control group     

Evaluation of maxillary central incisors on the noncleft and cleft sides in patients with unilateral cleft lip and palate—Part 1: Relationship between root length and orthodontic tooth movement

Objectives:To measure the root lengths of maxillary central incisors (U1) and evaluate the relationship among U1 root length, tooth movement, and type of treatment appliance in patients with unilateral cleft lip and palate over a long-term follow-up period.Materials and Methods:Occlusal radiographs of 30 patients with unilateral cleft lip and palate, acquired less than 6 months before secondary alveolar bone grafting (SBG, T1) and after edgewise treatment (T2), were measured for U1 root length (R1 and R2, root lengths at T1 and T2, respectively). Frontal and lateral cephalometric radiographs acquired at eruption of U1 (T0), T1, and T2 were evaluated to determine the inclination and position of U1.Results:The average values of R1 and R2 on the cleft side were significantly lower than those on the noncleft side. Frontal cephalometric analysis revealed that the horizontal distance of the root apex from the median vertical line at T0 on the cleft side was significantly smaller than that on the noncleft side and was correlated with short U1 root length on the cleft side. On the other hand, R1 in patients treated with maxillary protraction appliances between T0 and T1 was significantly shorter than that in patients without maxillary protraction appliances. However, none of the changes in cephalometric measurements were correlated with root length.Conclusions:In patients with unilateral cleft lip and palate, the short root length of cleft-adjacent central incisors might be associated with the horizontal position of the root apex. In addition, orthodontic treatment with a maxillary protraction appliance before secondary alveolar bone grafting might be associated with short U1 root length.     

A comparison of growth impairment and orthodontic results in adult patients with clefts of palate and unilateral clefts of lip, palate and alveolus

OBJECTIVE: To evaluate and compare the long-term aesthetic and functional results of surgical and orthodontic treatment in patients with cleft palate and unilateral cleft lip, palate, and alveolus. DESIGN: 30 patients with unilateral cleft lip, palate, and alveolus and 30 patients with isolated cleft palate, mean age of 18.9 years, were evaluated by cephalometric and model analysis a mean of 1.5 years after orthodontic treatment. In each group the surgical treatment has been similar. RESULTS: Model analysis: The sum of every mesiodistal tooth diameter in the maxilla and in the mandible was recorded according to the Bolton analysis. Twenty patients with unilateral cleft lip, palate and alveolus had relatively large upper dental arches and nine had relatively large lower dental arches. Twenty-two patients with cleft palates had large upper dental arches and seven had large mandibular arches. Eleven patients with unilateral cleft lip, palate, and alveolus and 18 patients with cleft palate had a negative space supply (the sum of the mesiodistal tooth diameters compared with the sagittal length of the alveolar ridge) in the region of the lateral teeth. All patients had persistent transverse space deficits that were increased on the side of the cleft in patients with cleft lip, palate, and alveolus. These unilateral transversal space deficits were recorded in 22 patients with unilateral cleft lip, palate, and alveolus and in 8 patients with isolated cleft palate. Sagittal measurements were reduced in 26 patients with unilateral cleft lip, palate, and alveolus and in 23 patients with cleft palate alone. The alveolar midline of the maxilla and the mandible were displaced in 25 patients with unilateral cleft lip, palate, and alveolus and in 19 patients with isolated cleft palate. Lateral cephalometric analysis: The lateral cephalograms taken at the same time as the models showed a mean SNA of 76.8 degrees and a NL-NSL angle of 8.7 degrees, indications of a tendency towards maxillary retrognathia in patients with unilateral cleft lip, palate, and alveolus. Patients with cleft palate had a mean SNA of 79.6 degrees and NL-NSL angle of 8.1 degrees. The anterior facial vertical index was within normal limits in patients with cleft lip, palate, and alveolus (44% vs 56%). An anterior facial height index of 42% compared with 58% in patients with isolated cleft palate indicated a slight reduction in midface height with an increase in the lower face as a consequence. CONCLUSION: Orthodontic and surgical treatment can result in satisfactory results on model analysis. However, there is specific growth impairment of the maxilla 1.5 years after termination of orthodontic treatment and this influences the final cephalometric analysis, particularly in patients with cleft lip, palate, and alveolus.