共查询到20条相似文献,搜索用时 62 毫秒
1.
2.
3.
4.
乳房外Paget病1例 总被引:1,自引:1,他引:0
患者男,72岁。因外阴部红斑、渗出伴瘙痒4年,于2005年5月6日就诊。患者4年前无明显诱因阴茎根部出现红斑伴瘙痒,皮损逐渐向邻近皮肤蔓延,时有渗液及脓性分泌物,曾多次在外院就诊,均诊断为湿疹,给予曲安奈德益康唑乳膏等药物治疗,皮损时好时坏,范围逐渐扩大,病程中无发热、消瘦、乏力等。既往有痛眦病史20年,高血压病史1年余。体格检查:系统俭查未见异常。[第一段] 相似文献
5.
6.
7.
患者男,73岁。阴茎根部、阴囊出现红斑伴瘙痒13年,糜烂、渗出、溃疡、出现肿物伴异味1年。组织病理示局部区域有表皮下浸润,PAS(+),Alcianblue(-),免疫组化CEA(3+),CK(2+),HMB45(-),S-100(-)。诊断:乳房外Paget病。 相似文献
8.
患者男 ,64岁。阴囊皮疹偶伴渗出、瘙痒 10年。病理检查示 :全层表皮均见Paget细胞 ,有的成巢状 ,个别真皮乳头可见基底突破。诊断为 :乳房外Paget病 ,突破基底膜。 相似文献
9.
患者女,73岁.外阴及会阴红色斑片、糜烂3年伴疼痛1年,于2011年7月18日就诊.患者3年前无明显诱因外阴和阴唇部出现红斑,无糜烂,无自觉症状,未经治疗.皮损逐渐向会阴部发展,并且小阴唇红斑上出现点状糜烂伴少许渗液.曾在当地妇产科就诊,具体诊断与用药不详,未见好转.近1年患者自觉皮损持续性隐痛,且肛周出现红斑,无尿频、尿痛、无腹痛、腹泻,无发热.自起病以来患者精神、饮食、睡眠较差.2001年8月15日曾在当地医院行直肠腺癌手术治疗. 相似文献
10.
11.
12.
The giant condyloma acuminatum (GCA), also known as Buschke–Löwenstein tumor (BLT), is a type of human papilloma virus‐associated sexually transmitted infection. Treatment options for condyloma acuminatum remain controversial, but surgery seems to be the best option. The management of GCA during pregnancy is more complicated since one has to evaluate the condition of both the mother and the fetus. In this report, we presented a GCA case in a pregnant woman with giant masses that covered the perineal and perianal region. Considering the gestational age and the fetal neurological risk from the anticipated lengthy procedure of mass removal surgery for tumor of this size, we decided to resect the tumor 2 weeks after the infant was delivered via C‐section. 相似文献
13.
14.
15.
16.
Gunnar Wagner Michael Max Sachse 《Journal der Deutschen Dermatologischen Gesellschaft》2011,9(6):448-454
Extramammary Paget disease is a rare malignant neoplasm. With regard to the pathogenesis, two prognostically different forms can be distinguished. The primary form of extramammary Paget disease is an in situ carcinoma of the apocrine gland ducts. In contrast, the secondary form is characterized by an intraepithelial spread due to an underlying carcinoma of the skin or other organ systems. Extramammary Paget disease occurs in older patients. The predilection sites include the entire anogenital skin and less often the axillary region. We present five different patients with this disease, thereby demonstrating its variation in clinical morphology. The lesion usually presents as an erythematous sharply defined spot. The polygonal borders, caused by the centrifugal growth of the tumor, may provide a diagnostic clue. The treatment of choice for extramammary Paget disease remains Mohs’ microscopic surgery. However, radiotherapy or topical applications may be alternative treatment options in selected cases. In patients with the secondary form of extramam‐mary Paget disease, treatment of the primary tumor is the main approach. 相似文献
17.
本文报道17例儿童CA患儿,14例患儿的父母有CA病史,所有女患儿处女膜完整。儿童感染CA可通过非性接触途径。 相似文献
18.
采用外科破坏法。干扰素局部浸润注射、自体疣移植、口服免疫应答调节剂、中药熏洗坐浴等5联疗法治疗肛门尖锐湿疣,对照组采用疣体切除术加干扰素局部注射。结果表明,两组治愈率和复发率分别为100%、0%和82.5%、27.0%,差异有统计学意义(P<0.01)。 相似文献
19.
Nadiya Chuchvara Catherine Reilly Attiya Haroon Cindy Wassef Amin Maghari Babar Rao 《Journal of cutaneous pathology》2020,47(12):1170-1174
Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we describe a case of a 67-year-old African American woman with a large, pigmented axillary patch that exhibited features of melanoma on RCM, guiding the clinician to perform an excisional biopsy. While traditional histopathology resembled melanoma, immunohistochemistry staining was performed and revealed PEMPD. We highlight an uncommon clinical presentation of PEMPD disease and identify morphologic mimickers of melanoma on RCM—as well as differentiating features. 相似文献
20.
目的探讨乳房外Paget病的临床、病理特点及影响生存率的因素。方法回顾性分析2000-2010年间本院收治的19例乳房外Paget病患者的临床资料。结果 19例中女4例,男15例,平均年龄(70.26±8.90)岁。确诊时病程1月~6.5年,平均43月。临床表现主要为红斑、糜烂及湿疹、皮炎样皮损。手术治疗13例,其中2例复发;光动力治疗5例;未治疗1例。随访期间死亡7例,5年生存率61.20%。单因素变量分析显示淋巴结转移、肿瘤细胞侵袭至真皮、伴发其他肿瘤或远处转移、CEA水平升高与患者生存率有关。结论乳房外Paget病早期诊断困难,复发率高,淋巴结转移、伴发肿瘤或远处转移者预后差,需长期随访。迁延不愈的"湿疹"患者应尽早行皮肤活检,免疫组化检查可提高早期诊断率并指导早期治疗。 相似文献