单孔腹腔镜手术在妇科良性疾病中的应用体会

目的 研究单孔腹腔镜手术在妇科良性疾病中的临床效果。方法 选取100例妇科良性疾病患者,根据随机数字表法分为A组与B组,每组50例。A组实施单孔腹腔镜手术治疗,B组实施多孔腹腔镜手术治疗。比较两组临床效果。结果 两组手术时间比较,差异无统计学意义（P>0.05）,A组术中出血量（34.16±1.54）ml少于B组的（51.08±9.23）ml,差异有统计学意义（P<0.05）。A组术后6、12、24 h的视觉模拟评分法（VAS）评分均明显低于B组,肛门排气时间短于B组,差异有统计学意义（P<0.05）。结论 在妇科良性疾病的治疗中,单孔腹腔镜手术的应用价值确切,可减轻患者术后疼痛,缩短术后肛门排气时间,并增强美观度,值得临床推广与应用。     

妇科良性疾病腹腔镜术后中重度疼痛相关影响因素分析

Objective?To investigate the occurrence and influencing factors of moderate and severe pain after laparoscopic surgery for benign gynecological lesions. Methods?A total of 114 gynecological patients undergoing laparoscopic hysterectomy and adnexectomy in Peking University People's Hospital from April 2021 to July 2021 were prospectively selected as the study subjects, and 100 patients with benign gynecological diseases were included in the analysis. According to the degree of postoperative pain, they were divided into moderate and severe pain group (63 cases) and mild pain group (37 cases). According to the number of organs involved in the operation, the patients were divided into three groups: single organ operation (45 cases), double organ operation (30 cases), three or more organs operation (25 cases). Height, body mass, body mass index (BMI), preoperative pain degree, operation type, operation time and analgesic drug dosage were compared between mild pain group and moderate and severe pain group 72 h after operation. Univariate and logistic multifactor regression were used to analyze the risk factors of postoperative pain. Results?The incidence of postoperative pain in multiple organ surgery (80.00%, 20/25) was higher than that in single organ surgery (51.11%, 23/45) and double organ surgery (66.67%, 20/30), and the difference was statistically significant (P＜0.05). Logistic multivariate regression analysis showed that multiple organ surgery (OR=7.541, 95%CI: 2.035-27.952, P=0.0025) and analgesic drug dosage (OR=1.097, 95%CI: 1.009-1.193, P=0.0303) were risk factors for postoperative pain (P<0.05). Postoperative pain significantly affected the activity and sleep of patients (P<0.05). Conclusion?The incidence of postoperative pain in gynecological laparoscopic multi-organ surgery is high, and the pain significantly affects postoperative activity and sleep of patients. Pain management should be carried out according to different surgical types.     

妇科良性疾病腹腔镜术后中重度疼痛相关影响因素分析

目的 探讨妇科良性疾病腹腔镜手术后中重度疼痛发生情况及影响因素。方法 前瞻性选取2021年4月至2021年7月北京大学人民医院114例因妇科良性疾病行腹腔镜下子宫、附件切除术患者作为研究对象,其中100例患者符合标准纳入分析。按照术后疼痛程度分为中重度疼痛组（63例）,轻度疼痛组（37例）;并按手术涉及脏器数分为三组：单脏器手术（45例）、双脏器手术（30例）、3个及以上脏器手术（25例）。进行术后问卷调查,比较术后72 h轻度疼痛与中重度疼痛组患者身高、体质量、体质指数（BMI）、术前疼痛、手术类型、手术时间、麻醉镇痛用药及疼痛对患者活动及睡眠影响。采用单因素和logistic多因素回归分析术后疼痛的危险因素。结果 多脏器手术术后疼痛发生率（80.00%, 20/25）高于单脏器手术（51.11%, 23/45）及双脏器手术（66.67%, 20/30）,三组比较,差异有统计学意义（P <0.05）;而三组术前疼痛状态、BMI分级、手术时间比较差异无统计学意义（P>0.05）。logistic多因素回归分析显示,多脏器手术（OR=7.541, 95%CI:2.035～27...     

经脐单孔腹腔镜在妇科附件良性疾病中的临床应用价值#br#

Objective?To study the clinical application value of laparoendoscopic single-site surgery (LESS) in benign adnexal lesions. Methods?A retrospective case analysis of 208 patients who underwent accessory surgery in our hospital from May 2017 to March 2019, 68 of which underwent laparoendoscopic single-site surgery(LESS group) and 140 underwent general surgery laparoscopic surgery (control group), compare the perioperative period and follow-up of the two groups of patients. Results?The operation time of different diseases in LESS group was longer than that of the control group (P＜0.05) [unilateral ovarian teratoma/cystectomy (49.7±7.3) min vs (33.6±7.2) min]; bilateral ovarian teratoma resection [(68.2±7.3) min vs. (50.1±4.2) min]; the postoperative hospital stay in LESS group was shortened (P＜0.05) [(3.12±0.39) d) vs. (3.57±0.29) d],  and the 24-hour pain (VAS) score of the LESS group was lower than that of the control group (P＜0.05) [(3.23±0.12) points vs (3.45±0.20) points], the postoperative incision cosmetic satisfaction was higher (P＜0.05). There was no statistically significant difference between the two groups of patients in intraoperative blood loss, postoperative exhaust time, postoperative time to get out of bed, postoperative analgesics use, and postoperative fever (P＞0.05); There were no complications such as visceral injury and incisional hernia after the operation. Conclusion?The application of LESS in benign adnexal lesions is feasible. Although the operation time is long relatively, it has the advantages of fast postoperative recovery, postoperative pain reduction and cosmetic advantages.     

恒康正清在妇科手术前肠道准备中的应用

目的研究恒康正消口服灌肠剂在妇科手术前肠道准备中的应用，评价其耐受性及临床效果。方法我院妇科从2004年11月～2005年1月共有50例患者行妇科手术前接受恒康正清口服灌肠剂进行肠道准备。平均年龄51．2岁（29～75岁）。其中普通手术组16例，阴式手术组20例，恶性手术组14例。同期常规手术口服甘露醇行肠道准备10例为对照。术前1日给予恒康正清（甘露醇）口服，观察记录口服恒康正清过程中有无不适反应评价其耐受性。根据患者末次排便或灌肠排出物的性状及术中肠管胀气情况评判肠道准备的满意程度。术后观察患者有无腹胀，术后排气时间评价术后患者恢复情况。结果50例患者中，18例（36％）患者出现恶心、呕吐、腹痛、腹胀反应，但程度均较轻，患者可以耐受，未影响术前准备及手术。口服恒康正清普通手术组与对照组相比患者平均排便次数分别为6．0次和3．4次，两者比较差异有显著性，普通手术组满意率为81．3％，阴式手术满意率为95．0％。恶性手术组满意率为85．7％。普通手术组术后平均排气时间为40．5h，阴式手术组为铝．0h，恶性手术组为73．7h，前两组差异无显著性，但与恶性手术组相比差异有显著件。对照组平均排气时间为31．2h，与普通手术组相比差异无显著性。结论恒康正清口服肠道准备患者耐受性好．准备效果及术后患者恢复与甘露醇相比差异无显著性，适合妇科常用的手术前准备。     

妇科良性疾病患者腹腔镜与开腹手术术后静脉血栓发生率的Meta分析

目的:通过Meta分析了解妇科良性疾病患者腹腔镜与开腹手术的术后静脉血栓发生率。方法:检索2000至2016年中国生物医学文献数据库(CBMdisc)、中国期刊全文数据库(CNKI)、维普数据库(VIP)、万方数据库、Pub Med、荷兰医学文摘数据库(EMBASE)、Web of science等数据库收录的有关妇科良性疾病患者行腹腔镜与开腹手术的术后静脉血栓发生率的相关文献,按纳入及排除标准筛选文献、提取资料并评价质量。采用Stata 13.0软件进行Meta分析,并对年龄、性别及区域等因素进行亚组分析。结果:共纳入相关文献24篇。Meta结果表明,腹腔镜和开腹手术均能增加患者术后的D-二聚体浓度,差异无统计学意义(SMD=0.77,95%CI为-0.08~1.63,P=0.075)。腹腔镜组的术后VTE发生率0.0%~14.03%,平均2.10%;开腹手术组的术后VTE发生率0.63%~14.28%,平均4.90%。Meta结果表明,行腹腔镜手术患者的术后VTE发生率较行开腹手术者低,差异有统计学意义(OR=0.42,95%CI为0.33~0.54,P0.001)。结论:对于妇科手术患者,腹腔镜和传统开腹手术都会造成术后D-二聚体浓度增高,开腹手术组增高更明显,但结论尚需更深入的验证;对于妇科手术患者,腹腔镜手术较传统开腹手术的术后VTE发生率低。     

经脐单孔腹腔镜与传统腹腔镜治疗妇科良性疾病的效果对比

目的 分析经脐单孔腹腔镜与传统腹腔镜治疗妇科良性疾病的方法与效果。方法 选取60例妇科良性疾病患者,按照随机抽签法将其分为对照组与观察组,各30例,分别实施传统腹腔镜与经脐单孔腹腔镜治疗,对比两组手术效果。结果 与对照组对比,观察组术后疼痛评分更低,术后住院时间更短,住院费用更少（P<0.05）。观察组治疗满意度96.67%较对照组的76.67%高（P<0.05）。结论 经脐单孔腹腔镜治疗妇科良性疾病效果更加确切,能够提高患者手术质量与治疗满意度,值得临床推广。     

妇科良性疾病的动脉介入治疗

早在 1976年Ｍｉｌｌｅｒ等[1] 首先运用选择性子宫动脉插管栓塞控制盆腔恶性肿瘤导致的大出血取得成功 ,从此将动脉介入技术引入妇科疾病的治疗领域。到目前为止 ,已从妇科恶性肿瘤的动脉灌注化疗、止血扩展到妇科多种良性疾病的诊断和治疗 ,并具有创伤小、恢复快、并发症少等优点 ,发展前景良好。现将妇科良性疾病的动脉介入治疗简述如下。1　子宫肌瘤　　子宫肌瘤是育龄妇女生殖系统最常见的良性肿瘤 ,发病率高达 2 0 %以上 ,约占女性良性肿瘤的 5 1 87% ,主要表现为月经过多、肌瘤压迫症状 ,约有 40 %的患者继发不同程度的贫血。　　多…     

妇科腹腔镜手术治疗良性卵巢肿瘤333例临床分析

妇科腹腔镜手术具有微创、术后恢复快等优点。近年来手术适应证不断扩大 ,几乎包括了所有妇科疾病。我院采用腹腔镜手术治疗良性卵巢肿瘤 333例 ,取得较满意结果 ,现报道如下。1　资料与方法1.1　一般资料　病例为我院 1994年 7月至 2 0 0 2年 9月因卵巢良性肿瘤或巧克力囊肿而做腹腔镜手术患者共 333例。年龄 19～ 4 6岁、平均 38岁。其中有手术史 :剖宫产术后 5 2例 ,阑尾炎术后 11例。术前诊断卵巢单纯性囊肿 182例 ,双侧 2 8例 ,直径 5～ 17cm ;卵巢巧克力囊肿 83例 ,双侧 36例 ,直径 3～ 6cm ;卵巢畸胎瘤 6 8例 ,双侧 14例 ,直径 5～ 8…     

经脐单孔腹腔镜手术治疗妇科良性疾病的临床效果分析

目的 比较经脐单孔腹腔镜与传统腹腔镜治疗妇科良性疾病的临床效果.方法 回顾性分析比较2019年8月至2020年8月于川北医学院附属南充市中心医院初始治疗为手术的妇科良性疾病患者的临床效果,其中卵巢良性肿瘤132例,子宫肌瘤90例,子宫腺肌症48例,卵巢子宫内膜异位囊肿45例,根据手术方式分为经脐单孔腹腔镜(观察组105...     

Perioperative bowel management for gynecologic surgery

Postoperative intestinal care after major gynecologic surgery has changed considerably. The purpose of this review was to describe these changes. Our findings are that (1) preoperative mechanical bowel preparation does not lower the risk of anastomotic leakage and infection, (2) elective postoperative nasogastric tube decompression increases postoperative pneumonia and does not decrease the incidence of other postoperative complications, (3) early feeding after major gynecologic surgery reduces hospital stay and does not increase (and may decrease) pneumonia and other postoperative complications, and (4) early feeding, gum chewing, bowel stimulation, alvimopan, and ketorolac may decrease the incidence of postoperative ileus.     

腹腔镜手术治疗巨大卵巢良性肿瘤25例分析

目的:探讨腹腔镜手术治疗巨大卵巢良性肿瘤的疗效。方法:回顾分析2003.01-2006.12期间腹腔镜手术治疗巨大卵巢良性肿瘤25例。结果:25例均在腹腔镜下完成手术,手术平均时间30.2±10.5min、术中平均出血量40.3±18.6ml、平均住院日4.3±2.1d,术后无严重并发症。结论:腹腔镜手术治疗巨大卵巢良性肿瘤疗效肯定,安全。     

改良单孔腹腔镜与传统三孔腹腔镜在妇科良性附件手术中应用的比较

目的 探究改良单孔腹腔镜与传统三孔腹腔镜在妇科良性附件手术中的有效性和安全性.方法 采用简单随机化分组方法,纳入2015年6月至2016年12月于北京大学第一医院因附件良性病变行腹腔镜手术的200例患者,随机分为改良单孔腹腔镜组(研究组,n=100)和传统腹腔镜组(对照组,n=100),比较两组手术时间、术后血红蛋白变...     

妇科肿瘤腹腔镜手术中超声刀应用技巧及副损伤防治

超声刀是一种把电能转换为机械能的手术器械,主要工作原理是通过刀头的振荡摩擦产生热能作用在组织上,具有凝血和切割同时完成、刀头温度低、侧向热传导小、无电流刺激等特点。在妇科恶性肿瘤手术的一些关键技术操作上有独特优势,提高了腹腔镜手术的安全性和减少了术后的一些并发症。超声刀引起的输尿管或肠管的损伤,仍然按照热损伤的原则进行防治和处理。     

Sexual functioning in patients following radical hysterectomy for stage IB cancer of the cervix

Abstract. Grumann M, Robertson R, Hacker NF, Sommer G. Sexual functioning in patients following radical hysterectomy for stage IB cancer of the cervix.
Despite extensive research on sexual dysfunction after gynecological cancer, uncertainty remains regarding the nature and extent of sexual problems following surgery for early cervical cancer. This study investigated whether radical hysterectomy for stage IB cancer of the cervix without adjuvant treatment entails short- or long-term sexual difficulties. Twenty patients with stage IB cervical cancer undergoing radical hysterectomy (CG), 18 women treated with hysterectomy for a benign gynecological condition (BG), and 20 gynecologically healthy women (HG) were studied. At 0, 4, and 8 months postoperatively, data were prospectively gathered using standardized questionnaires and specifically developed scales. Sexual functioning was covered in 15 specifically designed items and analyzed using Fisher's exact tests. For all other variables, group comparisons were computed using analysis of variance ( anova ) or nonparametric statistical equivalents. Nonsignificant trends, consistent across time and groups, resulted for most of the sexual variables. Preoperatively, cancer patients exhibited slightly better sexual functioning than the other two groups, but over time this decreased slightly. Conversely, sexual functioning among the patients with benign disease showed steady improvement. These results indicate that radical hysterectomy for stage IB cervical cancer does not entail major sexual sequelae. Because of the limited sample size of our study, conclusions must be drawn cautiously.     

Preoperative discrimination between ovarian carcinoma, non-ovarian gynecological malignancy and benign adnexal masses using serum levels of CA125 and the polymorphic epithelial mucin antigens CASA, OSA and MSA

Serum levels of the tumor associated antigens CA125, CASA, OSA and MSA were determined preoperatively in a non-consecutive series of patients with: invasive epithelial ovarian cancer (OC, n = 87), ovarian tumors of low malignant potential (LMP, n = 9), benign adnexal masses (BAM, n = 48) and other peritoneal and pelvic malignancies ( n = 48). In addition, serum levels of CASA, OSA, and MSA were determined in 3477 asymptomatic well women. Ninety-eight percent of the asymptomatic women had CASA levels < 6.0 U ml⁻¹, OSA levels < 5.5 U ml⁻¹ and MSA levels < 80.0 U ml⁻¹. Serum CA125 levels were> 35 U ml⁻¹ in 89% of OC, in 44% of LMP, and in 23% of BAM. Serum CASA levels were> 6.0 U ml⁻¹ in 58% of OC, in 0% of LMP, and in 0% of BAM. Serum OSA levels were> 5.5 U ml⁻¹ in 61% of OC in 0% of LMP and in 4% of BAM. Serum MSA levels were> 80.0 U ml⁻¹ in 56% of OC, in 11% of LMP, and in 10% of BAM. When cut-off levels were set to exclude all patients with BAM, the best discrimination from OC using a single assay was achieved using CASA (58%). However, a combination of CASA and CA125 gave positive levels in 69% of OC at levels which precluded BAM. All markers were also elevated in some colon cancers, cervical cancers, uterine cancers and other peritoneal malignancies. A combination of CA125 and CASA levels, obtained preoperatively may assist the general gynecologist in avoiding potentially difficult oncologic surgery.