Nutritional status of vitamin A, E, C, B1, B2, B6, nicotinic acid, B12, folate, and beta-carotene in young women

To investigate the vitamin status of young Japanese women, dietary intakes of vitamin A, E, C, B1, B2, B6, B12, niacin, folate, and beta-carotene were assessed by a 3-d weighed food record in 150 female students aged 21-22. Whole blood levels of vitamin B1, B2, and nicotinic acid, and serum levels of retinol, alpha-tocopherol, vitamin B6, and beta-carotene were determined by HPLC. Vitamin B12 and folate in serum were measured by chemiluminescence immunoassay, and serum vitamin C was done by dinitrophenylhydrazine method. When the 6th revision RDAs for the Japanese (physical activity level 1) were applied, 46.7% of the females showed sufficient intake for vitamin A, 28.7% for E, 80.7%, for B1, 92.7% for B2, 54.7% for B6, 99.3% for niacin, 76.0% for B12, 34.0% for folate, and 54.0% for C. Fifty-nine percent of total vitamin A (microgRE) intakes were derived from beta-carotene. The mean+/- SD of energy intakes was low, 1.572+/-315 kcal. Significant correlations among intakes of energy and all these vitamins were found. Serum folate and ascorbic acid levels in the females with corresponding vitamin intakes above the RDA were significantly higher than in those with intakes below the RDA. There were significant correlations between blood vitamin levels and vitamin intakes in vitamin B12 (r=0.185), folate (r=0.255), vitamin C (r=0.272), and beta-carotene (r=0.319). Mean blood levels of folate, ascorbic acid, vitamin B2, B12, and beta-carotene were higher in the highest quartile of intake than in the lowest. The 95% confidence intervals of blood vitamin levels obtained from the females with sufficient vitamin intakes were nearly equal to those obtained from all subjects. Only a few females (0.7-4.7%) had their blood vitamin levels below the lower limits. Serum alpha-tocopherol levels were significantly correlated with serum levels of retinol, beta-carotene, and vitamin C. This data suggested that young women should increase suitable dietary food intakes in order to maintain good status of vitamin. Moreover, sufficient amount of physical activity would be expected for prevention of excessive energy intake.     

Nutritional status of the water-soluble vitamins in an active Chinese elderly population in Hong Kong

Dietary intakes of thiamine, riboflavin, nicotinic and ascorbic acid, together with the biochemical status of thiamine, riboflavin, pyridoxine and ascorbic acid, were determined in a cluster sample of 419 healthy active elderly subjects aged 60 years and above living in the community. Nicotinic acid intake per 1000 kcal (4.18 MJ) of food energy showed an age-related decrease in men, while women had higher ascorbic acid intakes than men. Between 38 and 98 per cent of this population have intakes of thiamine, riboflavin and nicotinic acid below the UK RDA values. Intakes of ascorbic acid were below the RDA for 17 per cent of men and 9 per cent of women. The prevalence of biochemical deficiency was 8, 14, 11.5 and 24 per cent for thiamine, riboflavin, pyridoxine and ascorbic acid respectively. A significant difference in intakes between groups with blood levels within and below the reference range was seen only for riboflavin, suggesting that factors other than low intake may be more important in contributing to low blood levels for thiamine and ascorbic acid. However, inaccuracies in dietary intake estimations may contribute to the poor correlation.     

The nutrient intakes of pregnant and lactating mothers of good socio-economic status in Cambridge, UK: some implications for recommended daily allowances of minor nutrients

1. Forty-two mothers from social classes I, II and III non-manual and twenty-one from social classes III manual M), IV and V were studied longitudinally. The mean daily nutrient intakes in months 4-9 of pregnancy, months 2-4 of lactation and 3 and 6 months post-lactation are presented and are compared with the UK and the US recommended daily allowances (RDA). 2. The quality of the diets (nutrients per 4184 kJ (1000 kcal] was found to be better than that of other adult female populations studied in the UK, except for a group of dietitians. 3. The mean daily intakes of nutrients for which there are UK RDA were almost all greater than 100% of the RDA. The exceptions were iron, which in the manual group (social classes IIIM, IV and V) was 85% of the RDA in pregnancy and 75% post-lactation, and vitamin D. 4. Among the nutrients for which there are US, but not UK RDA, only phosphorus and vitamin B12 intakes were greater than 100% of the RDA in both groups at all stages of the study. Intakes of other nutrients were below the RDA: pantothenate 70-91, vitamin B6, zinc, vitamin E and copper 40-72, folate 21-44, and biotin less than 20% of the RDA. 5. The bases of the RDA for adult women were examined; for most nutrients the information is limited. It was concluded that the RDA for magnesium, vitamin E and pantothenate are probably higher than necessary and that deficiency is unlikely; that zinc, copper, vitamin B6 and folate are probably 'marginal' nutrients for 'at risk' groups; and that information on biotin is insufficient even roughly to assess the dietary requirement.     

贵阳地区汉族、苗族、布依族孕妇营养调查

对贵阳地区170名汉族、苗族、布依族孕妇的孕中、后期进行营养调查。结果表明,该区孕中、后期孕妇膳食中热量的摄入基本达到孕妇供给量标准。热量来源分配基本合理。孕妇膳食中存在的主要问题是蛋白质摄入量不足,优质蛋白占总蛋白之比,除汉族达到30％以上外,苗族、布依族均在25％以下。钙、B_2。摄入量三组均明显低于孕妇供给量标准。汉族在孕后期,视黄醇摄入量仅达到供给量的73％。孕妇贫血患病率在26.92～50.00％。汉族、苗族、布依族三组新生儿出生体重、身长均无显著性差异(p>0.05),发育指标均属中等水平。     

Leucocyte ascorbic acid and pregnancy

1. Leucocyte ascorbic acid concentrations have been measured in 1147 females during early pregnancy and in smaller numbers of women before conception, throughout pregnancy and at 6 months post partum. 2. The leucocyte concentration in the 1st trimester was found to be affected by season, social class and smoking. Selecting individuals by extremes of social class, season and smoking produced two small populations with almost separate ascorbic acid distributions and mean concentrations of 21.7 and 45.1 microgram/10(8) leucocytes. 3. Early pregnancy had little effect on leucocyte ascorbic acid concentrations but values decreased in the second trimester. However, this was associated with a leucocytosis so that the total leucocyte ascorbic acid content of blood was unchanged. 4. Low ascorbic acid concentrations during the 1st trimester were not associated with subsequent spontaneous abortions, still-births or neonatal deaths, but there was an increased frequency of low values in women who gave birth to infants smaller than 3250 g. 5. The adequacy of ascorbic acid reserves in early pregnancy is discussed.     

The diets of pregnant and post-pregnant women in different social groups in London and Edinburgh: energy, protein, fat and fibre

1. Dietary records were obtained twice in pregnancy and once post-partum from 265 women from all social classes in London and Edinburgh. 2. The London women always had higher mean energy, protein, fat and fibre intakes. Significant between-region differences emerged. 3. Some between-social classes differences occurred, but were not consistently significant. 4. All mean energy and fibre intakes were lower, and protein and fat intakes were higher, than current recommendations. 5. Of lactating women 15% claimed to be dieting. 6. The percentage dietary energy derived from fat varied from 36 (in a dieting group) to 42.     

Effect of nutrition education on the nutritional status of low-income pregnant women of Mexican descent.

Low-income pregnant women of Mexican descent were studied to determine whether their food habits could be improved by nutrition education. Biochemical indices of nutritional status were also investigated. Twenty-four-hour dietary recalls were obtained at an initial interview and again at a final interview after a nutrition education program, which was offered to a randomly selected treatment group. At the initial interview, the mean nutrient intakes that were most often below two-thirds of the Recommended Dietary Allowance (RDA) were iron, vitamin A, thiamin, and calcium. The mean energy value of the diets was also frequently below the RDA. At the final intakes, although the mean energy values and the calcium and carbohydrate of both the control and treatment groups increased significantly, the following improvements in dietary intakes were seen only within the treatment group: 1) there were significant increases in the mean intake of protein, ascorbic acid, niacin, riboflavin, and thiamin, 2) there were significant decreases in the percentage of intakes below two-thirds of the RDA for ascorbic acid and riboflavin, and 3) there was a significant decrease in the incidence of multiple low nutrient intakes. These dietary improvements, which occurred only in the treatment group, suggest the effectiveness of the nutrition education program. The most common biochemical deficiencies were of folic acid, thiamin, and riboflavin. Except for an improvement in mean serum folate levels, the biochemical indices for the treatment group did not appear to be influenced by the nutrition education. It is possible that the vitamin and mineral supplements which were taken by 80% of the women could have obscured improvements in biochemical indices which may have been due to the education program.     

Ascorbic acid requirements for smokers: analysis of a population survey

The recommended dietary allowance (RDA) of ascorbic acid for smokers was recently increased from 60 to 100 mg. To determine whether this new RDA for smokers is sufficient to reduce the risk of low serum ascorbic acid (AA) concentrations (LoC) to the same concentration as nonsmokers, we analyzed the dietary intakes and serum concentrations of AA in 11,582 adult respondents in the National Health and Nutrition Examination Survey (1976-1980). Serum AA concentrations and the risk of LoC (serum ascorbic acid levels less than 23 mumol/L) for smokers consuming different amounts of AA were compared with those for nonsmokers whose AA intake exceeded the RDA (60 mg). Serum AA concentrations were reduced, and risk of LoC increased, in smokers maintaining AA intakes greater than 60, 100, and 150 mg. Only smokers consuming greater than 200 mg AA/d had serum ascorbate concentrations and risk of LoC equivalent to nonsmokers meeting the RDA.     

Mineral content of foods and total diets: the Selected Minerals in Foods Survey, 1982 to 1984

The 234 foods of the FDA's Total Diet Study were collected four times per year form mid-1982 to mid-1984 and analyzed for 11 essential minerals. Daily intakes of the minerals were estimated for eight age-sex groups of the U.S. population. Levels of calcium, magnesium, iron, zinc, copper, and manganese were low (less than 80% of the RDA or below the low end of the Estimated Safe and Adequate Daily Dietary Intake range) for some or all age-sex groups. Those most at risk of low intakes were young children, teenage girls, adult women, and older women. Non-discretionary sodium intake exceeded the upper Estimated Safe and Adequate Daily Dietary Intake range for two age-sex groups, and iodine was considerably above the RDA for all age-sex groups. Levels of potassium, phosphorus, and selenium were adequate for all groups.     

Plasma levels of antioxidant vitamins and cholesterol in a large population sample in Central-Northern Italy

Background: In a population-based multicenter case-control study of diet, life-style, and gastric cancer a large series of adults, aged 30–75 years (mean 58.9 yearss), were randomly sampled from the general population in 3 areas of Central-Northern Italy. Aim of the study: To evaluate the relationship between plasma levels of antioxidant vitamins and cholesterol, and sociodemographic characteristics, life-style factors, and dietary intake of selected nutrients in a sample of the Italian population. Methods: A fasting blood sample was available for 945 subjects (553 men, 392 women). The plasma concentrations of ascorbic acid, carotene, retinol, alpha-tocopherol, and cholesterol were determined by a centralized laboratory. All participants answered to a detailed questionnaire collecting information on sociodemographic and anthropometric characteristics, smoking, alcohol drinking, and dietary habits. Covariance analysis models, with post hoc Dunnett tests, including terms for age, sex, study center, and period of blood drawing, were used for selected multiple-way comparisons of mean values of plasma nutrients. Results: Mean plasma values of retinol were higher among men while women had higher levels of plasma carotene, ascorbic acid, alpha-tocopherol, and cholesterol. Plasma carotene levels showed an inverse association with body mass index, alcohol consumption, and smoking and a positive association with social class. Carotene concentrations were higher in plasma samples obtained in spring/summer, while ascorbic acid levels were higher in autumn/winter. Partial correlation coefficients between carotene and ascorbic acid (0.69 in men; 0.74 in women), between carotene and alpha-tocopherol (0.44; 0.37), and between alpha-tocopherol and ascorbic acid (0.45; 0.41). Plasma alpha-tocopherol and retinol correlated with plasma cholesterol. On the other hand, plasma carotene and ascorbic acid were correlated with their estimated dietary intakes, while the intakes of other nutrients, as expected, correlated rather poorly with the respective plasma concentrations. Conclusions: Socio-economic factors, life-style, and specific nutrient intake, in addition to gender, are related to nutrient plasma levels in Italian adults and may provide specific suggestions for the prevention of chronic diseases. Received: 8 December 1998, Accepted: 25 February 1999     

Recommended dietary intakes (RDI) of vitamin A in humans

Mean and median dietary intakes of vitamin A in the US are approximately 1000 and 624 retinol equivalents, respectively. In this paper a satisfactory vitamin A status is defined as a total-body pool that provides adequate vitamin A to meet all known physiological needs and a reserve for 4 mo on low intakes or during stress. Mean dietary intakes required to maintain an adequate body pool (ie, 20 micrograms vitamin A/g liver [0.07 mumol/g]) in reference 76-kg men and 62-kg women are 506 and 413 micrograms retinol, respectively. Recommended dietary intakes (RDI) for nearly all reference men and women are 700 micrograms and 600 micrograms, respectively. Vitamin A needs in infants, children, the elderly, and pregnant and lactating women are quantified. The toxicity of vitamin A in early pregnancy, for which a safe intake level is not known, is stressed. On many grounds these suggested lower RDI values are preferable to the 1980 RDA values.     

Dietary studies of children from a biracial population: intakes of vitamins in 10- and 13-year-olds.

Impact of vitamin supplements upon dietary intakes of eight vitamins was examined in 10- and 13-year-old children randomly selected from a biracial community, Bogalusa, LA. More younger children reported taking supplements daily (17%) than did adolescents (12%). Over 90% of the children surveyed had dietary intakes of vitamin E and niacin that met or exceeded the RDA. One-half to two-thirds of children using supplements had adequate intakes of ascorbic acid from diet alone. Children who most needed ascorbic acid supplements were the least likely to take them. One-quarter to one-half of the children did not consume the RDA levels of vitamin A, thiamine, and riboflavin. Adolescents had less adequate vitamin A intakes than younger children. In all surveys, a higher proportion of girls than boys had intakes that did not meet the RDA for vitamins B6 and B12. Vitamin intakes of Bogalusa children and adolescents were comparable to other U.S. surveys. Inclusion of vitamin E and niacin in supplements may be unnecessary.     

Dietary studies of children from a biracial population: intakes of vitamins in 10- and 13-year-olds

Impact of vitamin supplements upon dietary intakes of eight vitamins was examined in 10- and 13-year-old children randomly selected from a biracial community, Bogalusa, LA. More younger children reported taking supplements daily (17%) than did adolescents (12%). Over 90% of the children surveyed had dietary intakes of vitamin E and niacin that met or exceeded the RDA. One-half to two-thirds of children using supplements had adequate intakes of ascorbic acid from diet alone. Children who most needed ascorbic acid supplements were the least likely to take them. One-quarter to one-half of the children did not consume the RDA levels of vitamin A, thiamine, and riboflavin. Adolescents had less adequate vitamin A intakes than younger children. In all surveys, a higher proportion of girls than boys had intakes that did not meet the RDA for vitamins B6 and B12. Vitamin intakes of Bogalusa children and adolescents were comparable to other U.S. surveys. Inclusion of vitamin E and niacin in supplements may be unnecessary.     

僧人营养状况的研究

对五台山６３名僧人（和尚、喇嘛、尼姑）的营养状况研究结果表明：僧人摄入的能量及各种营养素,除ＶＢ１、Ｆｅ外,其他均不足。尤其是蛋白质、Ｃａ、ＶＡ、ＶＢ２、ＶＣ、Ｚｎ。生化检验,血中总蛋白、血红蛋白ＶＡ、ＶＣ、Ｃｕ、Ｃｕ／Ｚｎ均不同程度低于正常值,。除个别喇嘛外,绝大部分僧人血中胆固醇、甘油三酯在正常范围。４小时负荷尿中ＶＢ２、ＶＣ严重不足。血清总蛋白、ＶＡ不足和贫血以和尚、尼姑较重,而ＶＣ不足和甘油三酯超过正常值则以喇嘛较重。体检中僧人有１０％左右出现ＶＡ、ＶＢ２、ＶＣ缺乏病。另外发现在蛋白质摄入不足的情况下,摄入２０％以上的优质蛋白质能有效地减少血清总蛋白的不足和贫血。摄入脂肪以植物性脂肪为主时,可以降低血中胆固醇和甘油三酯含量。     

Mineral balances of men and women consuming high fiber diets with complex or simple carbohydrate

Calcium, copper, iron, magnesium, manganese, and zinc balances of 20 men, 19 premenopausal women, and 12 postmenopausal women were determined while they consumed self-selected diets or high fiber diets with either complex or simple carbohydrate. Self-selected intakes of calcium, magnesium, copper and zinc were generally below RDA levels. Iron intakes of premenopausal women were less than two-thirds RDA. Balances during the self-selected intake period of calcium in men and women and of magnesium and zinc in women were negative, but lower-than-usual intakes could have contributed to this. High fiber diets did not adversely affect zinc, copper, manganese or iron balances. Calcium and magnesium balances were generally negative, especially in women, even though intakes were adequate. Excretion of copper was increased in premenopausal women consuming the simple carbohydrate diet. The levels of magnesium and especially calcium needed to maintain balance when consuming a high fiber diet may be above present RDA levels.     

Energy and Nutrient Inadequacies in the Diets of Low-Income Women who Breast-Feed

Objective To assess the energy and nutrient intakes of women who are breast-feeding in relation to the Recommended Dietary Allowances (RDAs) for energy and nutrients during lactation.Design Survey using an interviewer-administered questionnaire and a 24-hour dietary recall.Subjects The subjects were 183 women breast-feeding at 3 months postpartum. All were living in low-income communities in Ontario, Canada, that were participating in the longitudinal prevention initiative, Better Beginnings, Better Futures.Statistical analyses Mann-Whitney U test to compare energy and nutrient intakes of women with incomes above and below the Statistics Canada poverty line.Results Median intake of energy (2,148 kcal) was below the RDA of 2,700 kcal. Compared with the RDAs, intakes of calcium (928 vs 1,200 mg), Mate (222 vs 280 μg), iron (13 vs 15 mg), thiamin (1.4 vs 1.6 mg), vitamin A (846 vs 1,300 retinol equivalents), and zinc (10 vs 19 mg) were below recommended values for women who are lactating. Although household income for 70% of the women was below the poverty line, differences in energy and nutrient intakes according to income group were not statistically significant.Applications Lactating women are at high risk of energy and nutrient inadequacies. Programs to increase breast-feeding rates, particularly among low-income communities, must include strategies to ensure adequate diets during lactation. J Am Diet Assoc. 1997;97:1283-1287.     

成都市城乡居民膳食组成及营养素的总膳食研究

应用总膳食研究方法对成都市城乡代表人群的膳食组成和16种营养素（碳水化合物、蛋白质、脂肪、视黄醇、硫胺素、核黄素、抗坏血酸、钙、铁、锌、镁、钾、钠、铜、锰、钻）进行了研究。结果表明：城市居民动物性食物消费普遍高于农村，其中，以猪肉为代表的肉类消费仍分别占城乡居民动物性食物消费总量的61．9％和87．6％；城乡代表性膳食组成仍以粮谷类和蔬菜等植物性为主；全市平均及城市多数食物消费水平已超过或接近推荐的2000年膳食目标，但农村与目标差距较大。全市平均及分城乡摄入的热量分别达到RDA的106．9％、102．1％和111．8％；蛋白质分别达到RDA的96．7％、104．7％和91，2％；铁、铜、锰、钴、钠的摄入量较充足，已分别达到我国RDA和WHO提出的ESADDI；但也存在全市平均及分城乡视黄醇当量、硫胺素、核黄素、抗坏血酸、钙、锌、钾均摄入不足以及城市脂肪摄入过高，农村蛋白质质量较差等值得重视的问题。与以往的研究结果比，居民的营养改善不明显。     

Ascorbic acid status of children with developmental disabilities.

Ascorbic acid status of thirty-nine white children with developmental disabilities, ages three to nineteen years, is reported. Mean daily ascorbic acid intakes were calculated from three-day food records. Biochemical assessment consisted of fasting serum levels and a 6-hr. load test. Nine children served as a control group for the load test only. Mean dietary intakes for the vitamin were 204 per cent of the allowance. The mean serum ascorbic acid value was 1.3 mg. per deciliter. Only two children had levels at the unacceptable deficient level. Following load tests, ten children were identified as low excretors (less than 17 per cent), nine were moderate excretors (17 to 23 per cent), and the rest were high excretors (above 23 per cent). All of the normal children were high excretors. Two of three children with low ascorbic acid intakes (below 66 per cent of the recommended allowance) were verified as deficient by their fasting serum levels and urinary recovery after a load.     

A dietary survey of older people in Edinburgh.

1. Dietary histories covering 1 week were obtained from 212 men and 263 women, aged 62--90 years, who formed a random sample of the older people living in a defined area of Edinburgh. The histories were validated by 2 d weighed-diet records for 219 of the subjects. 2. Nutrient intakes are given as mean values and standard deviations, and as percentage distributions of intake relative to the recommended intakes of nutrients. Intakes are also related to factors which might affect diet adversely. 3. Mean values obtained suggested that intakes were less than recommended intakes for more nutrients for women than for men, particularly values for energy and vitamin D. Values for percentage distributions indicated that a substantial proportion of all subjects had low intakes of ascorbic acid and vitamin D, that the energy intake of many women was low and that for most nutrients a greater proportion of men than of women had the recommended intake. Factors assocIATED With significant proportions of subjects with less than the recommended intakes were mental illness in women and deafness and severe dyspnoea in men. 4. Possible action to improve the diet of the elderly is discussed.     

Nutritional survey of highly trained women runners

Mean daily intakes from 3-day dietary records for calories, energy-providing nutrients, and selected minerals were calculated for 51 highly trained women runners. Selected blood constituents relating to mineral status were also measured. Intakes of calcium, magnesium, iron, and copper were above the amounts recommended by the National Research Council whereas zinc intake was below the recommended dietary allowances (RDA). Caloric intakes, although above the RDA for sedentary women, appeared low for women running 10 miles/day. Concentrations of serum ferritin and plasma zinc were indicative of marginal iron and zinc status in many of the women. Whether the nutrient content of the diets consumed by these women is adequate relative to energy output or whether training lowers nutrient requirements by enhancing metabolic efficiency will require further investigation.