前路内固定矫正结核性脊柱畸形

目的　总结前路病灶清除、椎体间植骨和前路内固定手术治疗结核性脊柱畸形的临床疗效 ,探讨前路内固定植入在脊柱结核外科治疗中的安全性和价值。　方法　 1997年 6月～ 2 0 0 1年5月 ,采用前路病灶清除、椎体间植骨和一期前路内固定手术治疗脊柱结核 18例 ,其中颈椎 1例 ,胸椎10例 ,胸腰段 2例 ,腰椎 5例。平均每例受累椎体 2 8个。脊柱后凸畸形角度 2 7 0°～ 75 5°,平均47 5°± 11 4°。均采用髂骨植骨。　结果　 18例病例均获得随访 ,平均随访时间 2 5个月。所有病例均未出现伤口深部感染或窦道形成 ,植骨均完全融合 ,平均融合时间为 3 6个月。后凸畸形矫正度数为 32 7°± 8 3°,后期矫正度丢失 3 2°± 2 8°。　结论　前路内固定手术在脊柱外科治疗中能有效地达到矫正后凸畸形、重建脊柱稳定性和促进椎体间植骨融合的目的 ,是一种安全和有效的治疗方法。     

Anterior reconstructive spinal surgery with Zielke instrumentation for metastatic malignancies of the spine

From March 1984 to April 1996, 60 consecutive patients with spinal metastasis underwent palliative surgery by anterior corpectomy and Zielke instrumentation. Their ages ranged from 21 to 76 years (mean 54 years). Thirty-two patients had metastasis to the thoracic spine, 20 to the lumbar spine, and 8 had both thoracic and lumbar metastases. The primary malignancies were lung cancer in 12 patients, colorectal cancer in 10, hepatoma in 9, thyroid cancer in 7, breast cancer in 3, and cancers of the stomach, kidney, nasopharynx, long bones, skin, and cervix in 1 patient each. A primary carcinoma was never identified in 13 patients. In the present series, 4 patients died within 1 month, and 56 patients were followed-up. All maintained spinal stability postoperatively. Forty of 52 patients with severe pain obtained significant symptomatic relief for 3 months or more, and 33 of the 46 paralyzed patients gained neural improvement. Sphincter dysfunction became better in 10 patients, and none became worse. We conclude that anterior corpectomy to decompress neural encroachment with instrumental reconstruction to stabilize the collapsed spine is a good adjunctive treatment in these highly selected patients.     

Zielke instrumentation

Zielke modified Dwyer's anterior spinal instrumentation to produce the Ventral Derotational Spondylodesis (VDS) System. The primary indication for VDS instrumentation is the treatment of progressive, single, major lumbar or thoracolumbar curves in idiopathic scoliosis. The surgical technique, including selection of appropriate curvatures and levels of instrumentation, is described. A group of 25 consecutive patients undergoing VDS instrumentation for lumbar or thoracolumbar curvatures was reviewed. The average correction of the major curve was 76%. The minor curvature was corrected with an average of 47%. A significant complication was a 20% incidence of pseudarthrosis and rod breakage. The implications of these problems are discussed. Zielke instrumentation is a powerful technique for the correction of selected curves. The system provides greater correction of the major curve, improved frontal and sagittal alignment, and preservation of distal motion segments.     

Segmental spinal instrumentation for neuromuscular spinal deformity

Seventy-six consecutive surgical cases of paralytic neuromuscular spinal deformity were retrospectively analyzed. Posterior arthrodesis with segmental spinal stabilization with Luque L-rods, sometimes preceded by anterior release, was done in all cases. The infection rate of 14.5% was observed to be markedly higher in patients with myelodysplasia. Deep placement of the rods lateral to the spine and well beneath full-thickness skin is recommended to reduce the incidence of this complication.     

Anterior thoracoscopic surgery followed by posterior instrumentation and fusion in spinal deformity

Many authors believe thoracoscopic surgery is associated with a lower level of morbidity compared to thoracotomy, for anterior release or growth arrest in spinal deformity. Others believe that anterior release achieved thoracoscopically is not as effective as that achieved with the open procedure. We evaluated the clinical results, radiological correction and morbidity following anterior thoracoscopic surgery followed by posterior instrumentation and fusion, to see whether there is any evidence for either of these beliefs. Twenty-nine patients undergoing thoracoscopic anterior release or growth arrest followed by posterior fusion and instrumentation were evaluated from a clinical and radiological viewpoint. The mean follow-up was 2 years (range 1–4 years). The average age was 16 years (range 5–26 years). The following diagnoses were present: idiopathic scoliosis (n = 17), neuromuscular scoliosis (n = 2), congenital scoliosis (n = 1), thoracic hyperkyphosis (n = 9). All patients were satisfied with cosmesis following surgery. Twenty scoliosis patients had a mean preoperative Cobb angle of 65.1° (range 42°–94°) for the major curve, with an average flexibility of 34.5% (42.7°). Post operative correction to 31.5° (50.9%) and 34.4° (47.1%) at maximal follow-up was noted. For nine patients with thoracic hyperkyphosis, the Cobb angle averaged 81° (range 65°–96°), with hyperextension films showing an average correction to 65°. Postoperative correction to an average of 58.6° was maintained at 59.5° at maximal follow-up. The average number of released levels was 5.1 (range 3–7) and the average duration of the thoracoscopic procedure was 188 min (range 120–280 min). There was a decrease in this length of time as the series progressed. No neurologic or vascular complications occurred. Postoperative complications included four recurrent pneumothoraces, one surgical emphysema, and one respiratory infection. Thoracoscopic anterior surgery appears a safe and effective technique for the treatment of paediatric and adolescent spinal deformity. A randomised controlled trial, comparing open with thoracoscopic methods, is required. Received: 11 October 1999 Revised: 20 April 2000 Accepted: 16 May 2000     

Anterior spine fusion using Zielke instrumentation for adult thoracolumbar and lumbar scoliosis

Analysis of adult patients undergoing anterior spine fusions with Zielke instrumentation between January 1983 and November 1986 was performed. Objectives were to review results of surgical treatment and identify factors affecting results. Charts, 3 foot standing anteroposterior and lateral and supine maximal side bending radiographs were reviewed. Subjective data were obtained by telephone. There were 26 patients, average age 41 years. Average radiographic follow-up was 48 months. Indications were pain and curve progression. Average correction was 63% of the instrumented curve. Average change of lordosis was 8 degrees and kyphosis was 6 degrees. Apical vertebral rotation corrected an average of 37%. Complications were: eight hardware failures, one deep infection, and two psychiatric events. The high-risk groups: curves greater than 60 degrees, patients older than 50 years of age, and rigid curves.     

前路内固定在治疗胸腰椎结核中的作用

目的探讨胸腰椎前路内固定系统在治疗椎体结核时可行性以及对胸腰椎结核的治疗效果。方法采用胸腰椎前路病变椎体切除加自体髂骨植骨治疗27例,并同期行前路椎体内固定系统进行固定。结果经平均3年的随访,27例患者结核均治愈,植骨与受骨区全部骨性愈合,融合时间平均7~8个月,后凸矫正角度平均16°。全组病例切口均一期愈合。无手术并发症。结论该术式对胸腰椎结核病灶可彻底清除,能较好地进行椎管减压和脊柱矫形,完成脊柱稳定性重建,有利于患者早期离床活动,提高治愈率。     

Mesh cages for spinal deformity in adults.

Correction of deformity including restoration of sagittal plane malalignment in patients with spinal disorders is facilitated by placement of structural allografts and cages into the anterior column. The effectiveness of these implants will be reviewed with a focus on anterior column implantation of titanium mesh cages. In a consecutive study of adult patients who had spinal fusions for sagittal plane deformities using structural titanium mesh cages, cage status, fusion status, and outcome were assessed. Followup ranged from 24 to 62 months (average, 33 months). No cage failure of extrusion was observed. The average segmental improvement in lordosis with cage implantation was 11 degrees with a loss of correction of less than 1 degree at latest followup. No radiographic gold standard for fusion assessment with metallic implants in the anterior column could be found in the literature. The use of radiographic techniques for fusion assessment and functional outcome data for patients with implanted titanium mesh cages will be discussed.     

Anterior instrumentation for the treatment of spinal tuberculosis.

BACKGROUND: Kyphosis and neurological impairment are the major residual problems of spinal tuberculosis after the microorganism has been eradicated with use of appropriate medications. Spinal instrumentation is needed to support anterior strut grafts in patients who have kyphosis that affects more than two levels. Most surgeons use posterior instrumentation. Anterior instrumentation, despite its advantages, has not been widely accepted, partly because of concerns about introducing foreign material into infected tissue. The purpose of the current study was to address those concerns. METHODS: Twenty-two patients who had tuberculosis of the spine with moderate-to-severe localized kyphosis and sixteen patients who had more than two involved levels had stabilization with anterior instrumentation. Antituberculous medication was used postoperatively according to a standardized regimen. The patients were followed to determine if there was any recurrence of the disease and if the correction had been maintained. RESULTS: The twenty-two patients who had involvement of one or two levels had an average correction of the deformity of 64 percent (range, 58 to 90 percent), and the sixteen patients who had more than two levels of involvement had an average correction of 81 percent (range, 75 to 97 percent). The correction was maintained in twenty-one patients, the maximum loss was 3 degrees in sixteen, and one patient died on the second postoperative day. There was no recurrence of the disease. CONCLUSIONS: We believe that anterior instrumentation is more effective than posterior instrumentation for reducing the deformity and stabilizing the vertebral column in patients who have kyphosis related to tuberculosis of the spine.     

The use of growth-sparing instrumentation in pediatric spinal deformity

The management of severe spinal deformity in the growing child remains a challenging problem. Nonoperative methods range from orthotics to casting to traction; however, in certain circumstances, these techniques cannot effectively prevent deformity progression or are not tolerated by the child and surgical methods are required. Current options for surgical management of spinal deformity in the growing child include definitive spinal fusion with or without instrumentation, selective fusion, growth modulation, spinal instrumentation without fusion, or more recently, the use of the vertical expandable prosthetic titanium rib. Historically, all of these methods have a significant complication rate and despite advances in technology and instrumentation, remain problematic. This article provides an overview of current methods and outcomes for spinal instrumentation in the growing spine.     

Spinal arthrodesis for spinal deformity using posterior instrumentation and sublaminar wiring

Summary One hundred consecutive patients with spinal deformity due to various diagnoses were treated by posterior spinal arthrodesis with instrumentation and multiple sublaminar wires. Both the Harrington and Luque rodding systems were used. A total of 1128 wire loops were passed. No patient developed paraparesis or paraplegia, but three had transient sensory disturbance. There were no cases of broken rods or wires. Forty-five of the patients had no postoperative support. This worked well for neuromuscular scolioses, but for idiopathic scoliosis there was a disturbing loss of correction in many cases. Fusion to the sacrum was best accomplished with the Galveston technique, other methods having a high rate of pseudarthrosis. The main benefits appeared to be the ability to stabilize neuromuscular patients without the use of external immbolization, and the correction of thoracic lordosis.Supported in part by the Medical Education and Research Association of Gillette Children's Hospital Read in part at: Scoliosis Research Society, Orlando, Florida, September, 1984. S.I.C.O.T., London, England, October, 1984     

Results with Zielke instrumentation for idiopathic thoracolumbar and lumbar scoliosis

Thirty-one patients (23 adolescent, eight adult) underwent spinal fusions with Zielke instrumentation for idiopathic thoracolumbar and lumbar scoliosis. Their curves averaged 55.2 degrees. In most patients the length of fusion did not extend beyond the major curve. Correction of scoliosis was 82% in adolescents and 59% in the adults. The kyphotic component of the curves was corrected from an average of 21 degrees to 8 degrees. Correction of the spinal vertebra rotation was 46% in the adolescent patients. The tilt angle of the vertebra at the lower end of the curve was reduced significantly. The fusion rate was 93.5%. Two of the adult patients developed pseudarthrosis. Major complications were not encountered. The Zielke instrumentation system in the management of idiopathic thoracolumbar and lumbar scoliosis offers the advantages of a relatively good correction and minimal segment fusion.     

Pseudarthrosis in adult spinal deformity following multisegmental instrumentation and arthrodesis

BACKGROUND: There have been few detailed reports concerning pseudarthrosis following spinal instrumentation and arthrodesis in adults with spinal deformity since the introduction of modern segmental fixation techniques. The purposes of this study were to analyze the prevalence, risk factors, and outcome scores on the Scoliosis Research Society Instrument-24 associated with pseudarthrosis following instrumentation and arthrodesis for the treatment of spinal deformity in adults. METHODS: A clinical and radiographic assessment of 232 adults with spinal deformity who were treated surgically at a single institution was conducted. The average age of the patients was 40.8 years, and the operation was a primary procedure in 150 patients and a revision procedure in eighty-two patients. All patients who underwent a long (four vertebrae or more) spinal instrumentation and arthrodesis with a minimum follow-up of two years were included in the analysis. Clinical outcomes were assessed with the Scoliosis Research Society questionnaire. RESULTS: Forty patients had a pseudarthrosis. Factors that were found to be significantly associated with pseudarthrosis were preoperative thoracolumbar kyphosis of >20 degrees (p < 0.0001), an age of more than fifty-five years (p = 0.001), arthrodesis to S1 compared with arthrodesis to L5 or a cephalad level (p = 0.002), and arthrodesis of more than twelve vertebrae (p = 0.037). Patients with a pseudarthrosis had lower total outcome scores on the Scoliosis Research Society questionnaire, on the average, than those without a pseudarthrosis (p = 0.001). CONCLUSIONS: The prevalence of pseudarthrosis following long arthrodesis with use of modern segmental spinal instrumentation for the treatment of spinal deformity in adults was 17%, and the clinical outcome in these patients can be negatively affected by the pseudarthrosis.     

Posterior transpedicular Zielke instrumentation of the lumbar spine

Thirty-three patients treated by posterior transpedicular Zielke instrumentation of the lumbar spine were followed 1.1-2.7 years postoperatively. The average age of the patients was 64 years. The transpedicular technique allowed excellent fixation in patients with poor bone stock secondary to osteoporosis and extensive laminectomy defects. In particular, it allowed distraction and realignment of asymmetrically collapsed foramina with relief of pedicular kinking, correction of lateral deformity, and correction of reduced and fixed listhetic segments. Complications included one broken rod in the immediate postoperative interval while in the hospital. There was no late breakage of rods. The technique of transpedicular fixation with the ability to selectively distract or compress individual segments prevented any further collapse or displacement and allowed correction of areas of scoliotic collapse with relief of root entrapment. A normal lordosis was maintained as indicated by preoperative and postoperative measurements.     

Analysis of results with Zielke instrumentation for thoracolumbar and lumbar curvature

Thirty-nine patients (idiopathic in 26, paralytic in 11 and congenital in 2) treated by Zielke instrumentation with fusion for thoracolumbar and lumbar curvature were reviewed. The average follow-up was 34 months. The corrections of scoliosis was 76% in the adolescent idiopathic group, 59% in the adult idiopathic group and 55% in the paralytic group; rotation corrected (38%). Kyphosis was reduced from 61 degrees to 20 degrees on the average by derotating the spine using the derotator followed by placing bone graft in the anterior disc spaces. The tilt angle of the lower end vertebra in the idiopathic group and the pelvic obliquity angle in the paralytic group were corrected remarkably. Fusion rate was 92.3%. Two of three pseudarthrosis were repaired by Harrington instrumentation and fusion. One was free from symptoms. Complications were frequent, though in most cases only minor.     

Spine fusion in cerebral palsy with L-rod segmental spinal instrumentation. A comparison of single and two-stage combined approach with Zielke instrumentation

The benefits of achieving rigid internal fixation and eliminating the need for postoperative external orthotic support with L-rod spinal instrumentation made it desirable for use in the surgical treatment of neuromuscular scoliosis. From May 1981 to May 1985, 31 severely involved cerebral palsy patients with progressive spinal deformity underwent posterior fusion and L-rod instrumentation. All patients except one were nonambulatory. Surgical indications included prevention of curve progression, correction of pelvic obliquity, and achievement of balanced spinal alignment in order to improve sitting balance and tolerance without external spinal orthotic support. Ten patients (Group I), with an average age of 15.2 years, with double major or flexible paralytic C-curves or scoliosis measuring less than 70 degrees, underwent posterior fusion and L-rod instrumentation only. Twenty-one patients (Group II), with an average age of 22.1 years, with thoracolumbar, lumbar, or rigid paralytic C-curves or scoliosis measuring greater than 70 degrees, underwent initial anterior release, bone grafting, and Zielke instrumentation followed by second-stage L-rod instrumentation. In Group I, scoliosis averaged 57 degrees and postoperatively 27 degrees (53% correction). In Group II, scoliosis averaged 88 degrees and postoperatively 36 degrees (63% correction). Fifteen Group II patients had posterior fusion extend into the sacrum using the Galveston technique. Six Group II patients were not fused into the sacrum. Scoliosis and pelvic obliquity were corrected in both groups. Torso decompensation improved to 2.7 cm in the Galveston group, but increased to 5.6 cm at follow-up in the patients not fused into the sacrum.(ABSTRACT TRUNCATED AT 250 WORDS)     

经前路松解联合后路固定治疗特发性脊柱侧凸

目的:评价经前路松解联合后路矫形对特发性脊柱侧凸的治疗效果。方法:回顾性分析我院收治的51例(男16例,女35例;年龄8～17岁,平均13.2岁)特发性脊柱侧凸行前路松解及后路脊柱畸形矫形植骨融合术患者的临床资料及治疗结果。结果:本组中行前路松解、植骨,阻滞椎间盘平均2.4个。联合后路椎弓根钉(钩)-棒系统内固定,植骨、融合。术后特发性脊柱侧凸Cobb角<90°者额状平面平均矫正率为57%,矢状面后凸平均矫正率为50%;Cobb角>90°者额状平面平均矫正率为71%,矢状面后凸平均矫正率为74%。术后随访10～35个月,平均随访21.6个月,无矫正度的丢失及其他神经系统及血管损伤并发症。结论:脊柱前路松解安全、有效,联合后路相适应内固定系统矫形、植骨治疗特发性脊柱侧凸可获得满意治疗效果。     

Unit rod segmental spinal instrumentation in the management of patients with progressive neuromuscular spinal deformity

Thirty-four nonambulatory patients with progressive neuromuscular spinal deformity were surgically managed using a 1/4" U-shaped double rod construct with segmental instrumentation from T2 to the pelvis accompanied by posterior spinal fusion. Diagnoses included 17 patients with cerebral palsy, six with spinal bifida, and 11 with other diseases (spinal muscular atrophy, Friedreich's ataxia, polyneuropathy, nemaline myopathy, and polio). Twenty-three patients had single uncompensated thoracolumbar curves, and 11 had a double curve pattern. The mean preoperative major curve was 66 degrees (range, 22-132 degrees), the secondary curve 58 degrees (range, 23-84 degrees). No postoperative spinal support was used. Mean curve correction was 36 degrees or 54.6%. There were four major complications, including two implant failures requiring revision and two patients sustaining excessive intraoperative blood loss necessitating completion of the procedure in a second stage. There were two neurologic complications including one case of postoperative seizures and an L4 monoradicular neuropathy in a spina bifida patient. Four patients had temporary postoperative ileus, one gastroesophageal reflex, and four had urinary tract infections. There were no significant postoperative pulmonary complications. Excluding the patients with rod failure, mean loss of correction at mean follow-up of 21.3 months was 6.5%. The stability and curve correction obtained using this system supports its continued use in patients with progressive neuromuscular scoliosis.