CT导引下3 cm以下肺结节切割针活检的价值

目的评价多排螺旋CT引导下经皮肺切割针活检直径≤3 cm肺结节的价值.方法 CT引导下经皮肺穿刺活检肺部病灶直径≤3 cm结节81例,用意大利或美国20 G活检针对病灶至少穿刺取材2次.结果肺结节穿刺准确率达100%,病理证实恶性病灶56例,良性病灶24例;其中结节太小取材少不能定性1例,诊断准确率为98.76%.并发症中发生气胸12例(14.81%)、咯血15例(18.52%),穿刺针通过肺大泡而没有引起气胸1例,无严重并发症发生.结论 CT引导经皮穿刺直径≤3 cm肺部结节活检的准确性高且发生并发症较低,可作为肺内3 cm以下孤立性结节灶在临床治疗前病理诊断的首选方法.     

孤立性肺结节的CT引导下经皮肺穿刺活检

目的　探讨CT引导下经皮肺穿刺活检术对孤立性肺结节的诊断价值。方法　回顾性分析于 1993 -0 3～ 2 0 0 1-0 3期间行CT引导下经皮肺穿刺活检并经手术病理、临床治疗或随访观察证实的资料完整的 61例孤立性肺结节病灶。采用美国Cook公司的抽吸式活检针和套管式自动活检枪 ,选择最佳穿刺层面及穿刺点获取标本。结果　 61例孤立性肺结节病灶中经手术病理、临床治疗或随访观察证实为恶性肿瘤者 47例 (原发性支气管肺癌 43例 ,转移癌 4例 ) ,良性病变者 14例。而CT引导下经皮肺穿刺活检诊断为恶性肿瘤者 43例 ,良性病变者 9例。并发症 :气胸 12例 (19.8% ) ,出血 5例 (8.2 % ) ,咯血 4例 (6.6% )。结论　孤立性肺结节的CT引导下经皮肺穿刺活检是一种创伤小而实用的定性诊断方法 ,具有较高的临床应用价值     

CT引导肺内小结节经皮穿刺活检术的临床应用

目的：评价CT引导经皮穿刺肺内直径≤1.5cm小结节的临床价值。方法：65例肺内小结节患者行CT引导经皮穿刺活检术,分析其敏感度、特异度、准确度及并发症。结果：恶性肿瘤的诊断敏感度92.3%（36/39）,阳性预测值100%;良性病变诊断特异度100%,阴性预测值89.7%（26/29）,总诊断符合率92.3%（60/65）。气胸发生率7.7%（5/65）,肺内出血发生率10.8%（7/65）,术后均未作特殊处理。结论：CT引导经皮穿刺肺内小结节直径≤1.5cm病灶准确度较高且并发症发生率较低。     

C臂CT在肺小结节经皮肺穿刺活检中的临床应用

目的 探讨C臂CT在肺小结节(直径≤3 cm)经皮肺穿刺活检中的应用价值.方法 2010年9月-2012年3月在C臂CT引导下行经皮肺穿刺活检的肺小结节55例,病灶直径1.0 ～ 3.0 cm.术前、术中及术后均行C臂CT扫描.结果 C臂CT引导下经皮肺穿刺活检病理诊断灵敏度86.8％(33/38),特异度100％,无假阳性病例,假阴性率13.2％(5/38);气胸11例(20.0％),2例行闭式引流术;咯血2例(3.6％),无需特殊处理而自愈.结论 C臂CT引导肺结节(≤3 cm)经皮肺穿刺活检术定位准确,能提高肺小结节穿刺阳性率,及时发现术后并发症,是值得推广的一种影像新技术.     

CT引导肺穿刺活检对不同大小病灶的应用价值

目的:探讨CT引导肺穿刺活检对不同大小病灶的应用价值.材料和方法:回顾性分析CT引导肺部病变穿刺活检184例.病灶按大小分为两组,其中≥3cm者122个,<3cm者62个,分析穿刺活检术对两组病变的诊断正确率和并发症发生率.结果:CT引导肺穿刺活检对肺内大、小病灶的诊断正确率分别为92.6%(113/122)和91.9%(57/62;P>0.05).<3cm病灶的气胸发生率(19.2%)明显高于≥3cm病灶(5.2%;P<0.01),前者出血发生率(44.2%)亦显著高于后者(15.1%;P<0.01).结论:CT引导肺穿刺活检对大、小病灶的诊断准确率均较高,对大病灶活检的安全性高于小病灶.     

胸部大血管旁直径≤3cm病灶CT引导穿刺活检技术的应用

目的:评价CT引导经皮穿刺活检术对邻近胸部大血管旁直径≤3cm病灶的临床应用价值。方法:采用CT引导经皮穿刺术对206例邻近胸部大血管的直径≤3cm病灶进行活检,并与手术或临床随访诊断结果进行对比,分析其敏感性、特异性、准确性及并发症情况。结果:本组中该方法对恶性肿瘤的诊断敏感度为82.7%(124/150),阳性预测值100%;对良性病变的诊断特异度为100%,阴性预测值68.3%(56/82);总诊断符合率为87.4%(180/206)。气胸发生率8.3%(17/206),肺内出血发生率9.2%(19/206),均未作特殊处理而自愈;病灶周围有肺气肿是气胸及肺内出血的危险因素(χ2分别为27.56和30.45,P<0.01),而病灶大小及深度与并发症无明显相关性(P>0.05)。结论:CT引导经皮穿刺活检术对邻近胸部大血管旁直径≤3cm病灶的诊断准确性较高且并发症少。     

CT引导经皮肺穿刺活检术(附53例报告)

目的:评价CT引导下经皮肺穿刺活检术的临床价值,并对并发症的发生、预防进行探讨.方法:对53例患者的55个肺部病灶进行CT引导下穿刺活栓,用COOK公司18G、21G活检针或活检枪进行病灶穿刺,穿刺后行细胞学,并对并发症进行分析.结果:55个病灶穿刺成功率100%,阳性率94%,敏感率94%,并发症发生率5%.结论:CT引导经皮肺穿刺活检术是一种安全可靠的检查方法,诊断准确率高.     

多层螺旋CT在经皮穿刺肺组织活检中的应用价值

目的探讨多层螺旋CT(MSCT)引导下经皮穿刺肺组织活检的技术方法,并评价MSCT在经皮穿刺肺组织活检中的应用价值。资料与方法对42例患者的42个肺部病灶进行MSCT引导下经皮穿刺肺活检。结果42个病灶均成功穿刺(成功率为100%)。肺外周小病灶的一次穿刺成功率为88.2%(15/17),肺门部病灶的一次穿刺成功率为86.7%(13/15)。病理检出40例,诊断成功率和活检准确率均为95.2%。术后并发肺出血2例,发生率为4.8%;气胸2例,发生率为4.8%。结论MSCT引导不仅能提高经皮穿刺肺外周部小病灶和肺门部病灶的技术成功率、诊断成功率和活检准确性,而且能减少并发症的发生。     

CT引导经皮肺穿刺切割活检对肺内疑难病变诊断的研究

目的:探讨CT导引下经皮肺穿刺切割活检技术及临床应用价值。方法:在CT定位导引下使用槽式切割活检针进行病理组织学检查。结果:110例病变中,12例肺内弥漫性病变,98例肺内局灶性病变。在局灶性病变中,邻近胸膜的病灶36例,邻近肺门的病灶6例,距穿刺点胸膜最远8. 5cm。病灶靶区刺中率98. 18% (10. 8/110 ) ,切割取材成功率92 . 72 % (10 2 /110 ) ,病理确诊率96 . 36 % (10. 6 /110 ) ,并发症19.0 9(2 1/110 )。结论:①让患者保持相对固定的呼吸屏气相位,精确控制进针深度、角度及穿刺路径是刺中病灶靶区、减少并发症的关键;②CT导引下经皮肺穿刺切割活检技术是肺内疑难病变定性诊断的理想方法,具有重要的临床意义     

CT引导下细针穿刺活检对肺部空洞性病变的诊断价值

目的 探讨CT引导下经皮细针穿刺活检在肺部空洞性肿块中的诊断价值.方法 97例肺内孤立性肿块或结节伴有空洞的患者,进行CT引导下经皮肺穿刺活检,以手术病理或1年随访的最终诊断为标准,计算CT穿刺活检的诊断准确率,比较不同病灶大小及空洞壁厚度下CT穿刺活检的诊断敏感度、特异度及准确率,并采用Logistic回归分析CT穿刺活检并发症的危险因素.结果 CT穿刺活检的敏感度、特异度及准确率分别为97.4％,90.0％及95.9％,不同大小病灶(直径＜2 cm或≥2 cm)、不同空洞壁厚度(＜5或≥5 mm)其敏感度、特异度及准确率无统计学差异(P＞0.05).9例(9.3％)CT穿刺后出现少量气胸,14例(14.4％)出现少许肺泡出血,穿刺并发症与病灶大小、空洞壁厚度、针道深度及穿刺针大小无相关性(P＞0.05).结论 CT引导下经皮细针穿刺活检安全,对肺部空洞性病变的诊断准确性高.     

经皮肺活检对肺部病变的临床诊断意义

目的 评价经皮肺活检术对原发性肺癌、肺转移性癌以及非恶性肺疾病的诊断价值.方法 回顾性总结近10年来436例经皮肺活检患者的临床资料,其中明确为原发性肺癌患者341例、肺转移性癌62例、非恶性肺疾病33例.统汁分析经皮肺活检术对上述疾病的诊断准确率及灵敏度.结'果原发性肺癌组经皮肺活检阳性321例,诊断准确率为94.7%、灵敏度94.1%;肺转移性癌组阳性32例,诊断准确率58.2%、灵敏度51.6%;非恶性肺疾病组阳性19例,诊断准确率以及灵敏度均为57.6%.436例患者中427例经皮肺活检获得足够病变组织标本,9例活检失败,活检成功率97.9%.全部患者共穿刺474例次,其中74例次出现并发症,发生率15.6%.主要并发症有气胸(63例次,13.3%)和肺内出血(56例次,11.8%).结论 临床上怀疑原发性肺癌的肺部病变,经皮肺活检术诊断准确率高,并发症少且轻微.对于考虑为肺转移性癌以及非恶性肺疾病,该技术尚有待进一步改进.     

CT引导下肺内孤立性病变经皮穿刺活检并发症的分析

目的分析肺外围型孤立病变CT引导下经皮穿刺活检并发症的原因。方法选取2002-10～2004-10连续2年内的所有肺内外围型孤立病变行CT引导下肺穿刺活检的患者71例,回顾性研究总结穿刺活检的并发症发生率与年龄、性别、穿刺针所经肺组织深度、肿块周围有无肺气肿表现、穿刺的次数、穿刺针的粗细等几个方面的关系。结果并发症共26例次,气胸3例(4.23%),肺内出血9例(12.67%),出现血痰或血痰加重13例(18.3%),胸膜反应1例(1.41%)。经统计学分析,并发症的发生与穿刺针所经肺组织深度、病变周围肺气肿及穿刺次数和穿刺针的粗细有明显的相关性。结论CT引导下肺内病变经皮穿刺活检并发症以血痰最常见。病灶离胸膜的间距、病灶周围肺气肿、穿刺次数及穿刺针粗细是经皮穿刺肺活检并发症的危险因素。     

CT-guided percutaneous transthoracic biopsy in the diagnosis of mediastinal masses: evaluation of 73 procedures

PURPOSE: This study was performed to evaluate the factors affecting the diagnostic accuracy and rate of complications of CT-guided percutaneous transthoracic needle biopsy of mediastinal masses. MATERIALS AND METHODS: We reviewed 73 consecutive mediastinal biopsies in 70 patients. Final diagnoses were based on a retrospective analysis of surgical outcomes, results of repeat biopsies or findings of imaging and clinical follow-up lasting at least 4 months. Benign and malignant biopsy findings were compared with the final outcomes to determine the diagnostic accuracy of the method. Finally, we analysed the complications. RESULTS: CT-guided percutaneous transthoracic needle biopsy provided adequate samples in 61/73 cases, with a total sample rate of 83.6%. Of these 61 biopsies, 51 yielded a correct diagnosis with specific histological typing, mainly in the case of thymoma and metastasis. Lymphomas were less reliably diagnosed. The overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy values were 83.6%, 100%, 100%, 35.3% and 83.6%, respectively. Pneumothorax was the most common complication (5.5%). CONCLUSIONS: CT-guided percutaneous transthoracic needle biopsy is an easy, reliable and safe procedure that obviates the need for exploratory surgery in medically treatable or unresectable cases. It should be the first invasive procedure in the diagnostic workup of mediastinal masses.     

CT引导下经皮肺穿刺活检对周围型肺部病变的诊断价值

目的探讨CT引导下经皮肺穿刺活检对周围型肺部病变的诊断价值及其安全性。方法对58例周围型肺部病变的患者,在CT引导下行经皮肺穿刺活检。结果 58例患者中穿刺标本经组织病理学检查确诊病例48例,确诊率为82.8%,其中恶性肿瘤32例,良性病变16例。术后出现有症状并发症7例,其中咯血2例,气胸4例,高热伴脓胸1例,总发生率为12.1%。结论 CT引导下经皮肺穿刺活检定位准确,成功率高,安全可靠,在周围型肺部病变诊断中具有较高的应用价值。     

CT-guided transthoracic needle aspiration biopsy of small (< or = 20 mm) solitary pulmonary nodules

OBJECTIVE: The purpose of our study was to determine the diagnostic accuracy and to analyze the factors influencing the diagnostic accuracy and incidences of pneumothorax and chest tube insertion rates for percutaneous CT-guided needle biopsy of small (< or = 20 mm) solitary pulmonary nodules. SUBJECTS AND METHODS: One hundred sixty-two patients with 162 small solitary pulmonary nodules underwent CT-guided transthoracic needle aspiration biopsy. The overall diagnostic accuracy, pneumothorax rate, and chest tube insertion rate were calculated. Factors influencing the diagnostic accuracy and pneumothorax rate were statistically evaluated. Influencing factors, diagnostic accuracies, pneumothorax rates, and chest tube insertion rates were statistically compared. RESULTS: Overall diagnostic accuracy, pneumothorax rate, and chest tube insertion rate were 77.2%, 28.4%, and 2.5%, respectively. Diagnostic accuracy was significantly affected by length of needle path and lesion size (p < 0.05). The pneumothorax rate was significantly affected by the percentage of predicted forced expiratory volume in 1 sec, the number of punctures, and the needle path length (p < 0.05). The chest tube insertion rate was significantly affected by the number of punctures (p < 0.05). For diagnostic accuracy, needle path lengths of 40 mm or less and lesion sizes greater than 10 mm were significantly more accurate than other factors (p < 0.05). For pneumothorax rates, a percentage of predicted forced expiratory volume in 1 sec of greater than 70%, a single puncture, and a needle path length of 40 mm or less were significantly lower than other factors (p < 0.05). CONCLUSION: CT-guided transthoracic needle aspiration biopsy is a useful diagnostic tool for small solitary pulmonary nodules smaller than 20 mm in diameter. The diagnostic accuracy is significantly improved for large (> 10 mm) lesion size and short (< or = 40 mm) needle path length.     

CT导引下胸部病变穿刺活检的临床分析

目的：评价CT导引下穿刺活检在胸部病变诊断中的价值。方法：有手术病理或临床随诊的胸部病变CT穿刺活检223例，其中125例133次活检为传统CT导引下活检，其余98例105次CT穿刺活检应用激光导引装置。结果：223例胸部病变中212例有临床诊断结果，CT穿刺活检诊断正确率为82．1％（174／212），对恶性病变的敏感率86．2％（131／152），特异性100％、对良性病变明确诊断率为71．7％（43／60）。并发症包括13．0％（31／238）发生气胸，1．3％（3／238）需要放胸腔引流管，5．0％（1／238）发生肺实质少量出血，0．8％（2／238）出现少量咳血。激光导引下CT穿刺活检诊断正确率为88．4％（84／95），明显高于传统CT导引下活检76．9％（90／117）的诊断正确率，两者在气胸发生率、每次活检平均胸膜穿刺次数方面无统计学差异。结论：CT导引下胸部病变穿刺活检是一种安全、准确、有效的诊断及鉴别诊断方法。激光导引装置在胸部CT穿刺活检中有较高的应用价值，尤其对于小病灶和中心性病变。与传统CT导引下活检相比激光导引下CT活检可提高诊断证确率、缩短活检时间。     

CT引导下经皮肺穿刺切割活检的价值及安全性

目的：评价CT引导下经皮肺穿刺活检对肺部疑难疾病的诊断价值及安全性。方法：回顾性分析有手术病理、临床或影像随访结果的CT引导下经皮肺穿刺活检105例,其中97例为肺部局限性病灶（A组）,8例肺部弥漫性病灶（B组）。结果：2组共有101例穿刺物结果与手术病理、临床或影像学随访结果相符：穿刺诊断正确率96．2％。A组穿刺诊断正确率（99．0％）高于B组（62．5％）（P〈0．01）。A组肺癌占79．4％（77／97;B组肺癌占60．0％（3／5）;二组差异无统计学意义（P〉0．05）。两组合计发生气胸24例;出血34例,其中咯血18例。结论：cT引导下经皮肺穿刺切割活检穿刺诊断正确率高,是肺内疑难病变定性诊断的理想方法;使用18G穿刺针,可减少穿刺次数、降低出血的发生。     

Transthoracic CT-guided biopsy with multiplanar reconstruction image improves diagnostic accuracy of solitary pulmonary nodules

OBJECTIVE: To evaluate the utility of multiplanar reconstruction (MPR) image for CT-guided biopsy and determine factors of influencing diagnostic accuracy and the pneumothorax rate. MATERIALS AND METHODS: 390 patients with 396 pulmonary nodules underwent transthoracic CT-guided aspiration biopsy (TNAB) and transthoracic CT-guided cutting needle core biopsy (TCNB) as follows: 250 solitary pulmonary nodules (SPNs) underwent conventional CT-guided biopsy (conventional method), 81 underwent CT-fluoroscopic biopsy (CT-fluoroscopic method) and 65 underwent conventional CT-guided biopsy in combination with MPR image (MPR method). Success rate, overall diagnostic accuracy, pneumothorax rate and total procedure time were compared in each method. Factors affecting diagnostic accuracy and pneumothorax rate of CT-guided biopsy were statistically evaluated. RESULTS: Success rates (TNAB: 100.0%, TCNB: 100.0%) and overall diagnostic accuracies (TNAB: 96.9%, TCNB: 97.0%) of MPR were significantly higher than those using the conventional method (TNAB: 87.6 and 82.4%, TCNB: 86.3 and 81.3%) (P < 0.05). Diagnostic accuracy were influenced by biopsy method, lesion size, and needle path length (P < 0.05). Pneumothorax rate was influenced by pathological diagnostic method, lesion size, number of punctures and FEV1.0% (P < 0.05). CONCLUSION: The use of MPR for CT-guided lung biopsy is useful for improving diagnostic accuracy with no significant increase in pneumothorax rate or total procedure time.