Diabetes in pregnancy: health risks and management

Diabetes in pregnancy is increasing and therefore it is important to raise awareness of the associated health risks to the mother, the growing fetus, and the future child. Perinatal mortality and morbidity is increased in diabetic pregnancies through increased stillbirths and congenital malformation rates. These are mainly the result of early fetal exposure to maternal hyperglycaemia. In the mother, pregnancy may lead to worsening or development of diabetic complications such as retinopathy, nephropathy, and hypoglycaemia. This review defines pregestational and gestational diabetes and the associated health risks to the growing fetus and mother. Management is discussed, focusing on clinical evidence based guidelines published by the American Diabetic Association and the UK National Institute for Health and Clinical Excellence on the management of pregnant women with pre-existing diabetes.     

Diabetes in pregnancy — matthews duncan revisited

Master, Colleagues, Ladies and Gentlemen, I am grateful for the honour you have done me in inviting me to give the Ninian Falkiner Memorial Lecture for 1982.     

还原型谷胱甘肽与糖尿病

还原型谷胱甘肽(GSH)存在于人体各种组织和细胞中,具有调节机体中蛋白质和核苷酸合成的作用,并与机体中的抗氧化能力有关。GSH对糖尿病大小血管病变、脂肪肝的发生发展起着重要作用。目前,GSH已用于糖尿病神经病变、糖尿病肾病、糖尿病脂肪肝等并发症的治疗。