Negative alliesthesia for sweet stimuli after varying ingestions of glucose (author's transl)

Ten normal fasted subjects received sucrose gustatory stimului before and after intragastric glucose loads. Each subject in 4 experiments received 0 g, 25 g, 50 g and 100 g glucose. Responses to sweet stimuli were recorded during the period following injection. Results show a negative alliesthesia (decreased pleasure to sweet stimuli) appearing in 15 min increasing up to a maximum at about 55 min, then decreasing. The more glucose ingested the bigger the effect. These results are compatible with a participation of negative alliesthesia to the conscious satiey perception.     

Une ulcération cutanée due à Rhodotorula mucilaginosa chez un enfant immunodéprimé

Human cutaneous infections due to Rhodotorula species as an emerged pathogens yeasts are rarely reported, particularly in skin folds, with the ability to infect immunocompromised as well as immunocompetent patient. In present case, we describe a fungal cutaneous infection due to Rhodotorula mucilaginosa in immunocompromised child, the patient has been diagnosed with retinoblastoma; the diagnosis was established by the cytological and clinical examination. However, the cytological examination found fungal forms. The diagnosis relies on the microbiological analysis of clinical samples but the interpretation of a positive culture should be part of and over all analysis that integrate clinical symptoms and risk factors. Most of cases of infection due to Rhodotorula were associated with central venous catheter in patients who were receiving immunosuppressors and cyotoxic drugs. The antifungal susceptibility testing was done; a fluconazol and ketoconazol showed susceptibles. The patient was treated by combinate antifungal therapy and empirical antimicrobial regimen for prophylaxis.     

Cytogenetic study of 88 cases of refractory anemia

Data obtained on 88 patients with refractory anemia or preleukemia, without previous cytotoxic treatment, showed medullar chromosomal abnormalities in 32%. In 45% of the cases, the disease had progressed to acute nonlymphocytic leukemia. A high frequency of acute transformation (78%) was observed in patients with abnormal clones. These results are different from those of the Second International Workshop on chromosomes in Leukemia. The discrepancies may be related to the difference between the cases selected for submission to the workshop and those of this study. Serial studies on 28 patients with abnormal karyotypes showed that two different populations of patients were investigated: one with a terminal smoldering phase of leukemia and the other with true preleukemic disease. In the latter group, no predictive karyotype evolution was seen.     

Extracorporeal photochemotherapy in mycosis fungoides

Objectives

Extracorporeal photo-chemotherapy (ECP, photopheresis) is an approved treatment modality for mycosis fungoides (MF). Our aim is to present our ECP data for MF.

A selective modulation of the olfactory bulb electrical activity in relation to the learning of palatability in hungry and satiated rats

We attempted to determine whether a neutral odor which had become palatable as a result of learning had also acquired the property of activating the mitral cells of the olfactory bulb of hungry rats to the same extent as the odor of their usual nutriment. Male Wistar rats have been accustomed for various times to eat, during a single daily meal, exclusively a synthetic diet, either flavoured or not with eucalyptol. The mitral cell multiunit electrical activity was recorded in chronically implanted hungry and satiated animals. It was shown that: (1) in the rats having received the flavoured diet for one month when grown up, eucalyptol behaved as a nonalimentary odor towards mitral cells; (2) in the rats having received the flavoured diet (already given to the mothers) from weaning to the test period, eucalyptol behaved as a food odor at the mitral cell level, but amyl acetate, a control odor, did not activate mitral cells in hungry animals; (3) the odor of the diet with or without eucalyptol activated mitral cells at first in hungry rats, and this property was reinforced, for either diet, by its consumption beginning early and maintained continuously. It was concluded that palatability is dynamically related to the animal's previous experience, and that its modifications induce various degrees of mitral activation in hungry rats. This property allowed an electrophysiological measure of odor palatability to be proposed. The results are discussed in relation to the behavioral and neurophysiological maturation of animals.     

Outbreak of cutaneous leishmaniasis: about 213 cases in the province of Tizi-Ouzou

Leishmaniases are parasitic diseases frequent in the Mediterranean Basin. In Algeria they occupy the first place among parasitic diseases and represent 35% of diseases with compulsory notification. This is an alarming situation because the extension of the disease can also deteriorate the epidemiological situation of the tuberculosis and the HIV/AIDS because of coinfection. The authors report a series of 213 cases of aden ulcers listed in the wilaya of Tizi-Ouzou within nine years, region known for endemia of infantile visceral leishmaniases.     

Sources of common computer-cardiologist discord in e.c.g. interpretations in ambulatory population

Based on clinical experience in performing mass computerised interpretations of e.c.g.s, some common sources of computer-cardiologist disagreements are presented. Examples are given along with a discussion of the technological or logical bases for discord. It is concluded that computer interpretations are generally reliable and accurate; however, disagreements sometimes occur in borderline cases, in tracings with much electrical ‘noise’ or in those where the transitions between different segments of the QRS complex are not well demarcated. A computerised e.c.g. interpretation system can help the cardiologist by providing all required measurements and most of the diagnostic statements. Thus, only review and validation of the processed tracings are needed. By continuously refining the program criteria based on the accumulated experience of many cardiologists, the reliability and acceptability of computer e.c.g. interpretations could be enhanced and expanded to screen large populations.