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Single‐staged vs. two‐staged implant placement using bone ring technique in vertically deficient alveolar ridges – Part 1: histomorphometric and micro‐CT analysis 下载免费PDF全文
Ken Nakahara Maiko Haga‐Tsujimura Kosaku Sawada Eizaburo Kobayashi Matthias Mottini Benoit Schaller Nikola Saulacic 《Clinical oral implants research》2016,27(11):1384-1391
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Simultaneous lateral bone augmentation and implant placement using a particulated synthetic bone substitute around chronic peri‐implant dehiscence defects in dogs 下载免费PDF全文
Ui‐Won Jung Jae‐Kook Cha Fabio Vignoletti Javier Nuñez Javier Sanz Mariano Sanz 《Journal of clinical periodontology》2017,44(11):1172-1180
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Periodontitis and peri‐implantitis are multifactorial diseases characterized by alveolar bone destruction mediated by the host response to a microbial challenge. Alveolar bone resorption mediated by epigenetics could be one of the mechanisms responsible for this destruction of alveolar bone. The relationship between epigenetic modifications and bone metabolism has been thoroughly investigated in bone remodeling, cancer, and rheumatoid arthritis, but evidence is low regarding the relationship between epigenetic modifications and alveolar bone loss related to periodontal and peri‐implant diseases. Therefore, we conducted a review of the pertinent literature based on a priori‐formulated focused questions and a screening strategy, in an attempt to comprehend the role of different epigenetic mechanisms in alveolar bone loss and to determine the current state with respect to their possible therapeutic applications in regenerative medicine. The review showed that the roles of DNA methylation, histone modifications, and non‐coding RNAs in bone loss have been investigated. The results indicate that epigenetic mechanisms can participate in periodontal and peri‐implant alveolar bone breakdown, suggesting their potential as therapeutic targets in alveolar bone regeneration. However, there is still only preliminary information regarding the possible therapeutic utility of these epigenetic mechanisms, suggesting a need for basic and translational research to assess the potential of such mechanisms in promoting alveolar bone regeneration. 相似文献
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Randomized clinical study assessing two membranes for guided bone regeneration of peri‐implant bone defects: clinical and histological outcomes at 6 months 下载免费PDF全文
Nadja Naenni David Schneider Ronald E. Jung Jürg Hüsler Christoph H. F. Hämmerle Daniel S. Thoma 《Clinical oral implants research》2017,28(10):1309-1317
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