Observations on the Curative Effect of Multi-needle Shallow Puncture on Simple Obesity

目的察浅刺多针法与常规针刺法治疗单纯性肥胖症的临床疗效.方法本按照循证医学的原则,40例单纯性肥胖患者随机分为浅刺多针法治疗组20例,常规针刺法治疗组20例.治疗每日1次,20次为观察疗程,在治疗前后分别记录体重、标准体重、体重指数、脂肪百分率、胸围、腰围、臀围,对所得相关资料进行分析.结果两组经20次治疗体重、腰围等均有明显改变,两组疗效比较,浅刺多针法治疗组明显优于常规针刺法治疗组(P＜0.05).结论刺多针法对单纯性肥胖有较好的临床疗效,其效果优于常规针刺组.     

Observation on the Curative Effect of Acupuncture on Child Tourette＇s Syndrome

目的讨论应用扶土抑木法针刺治疗儿童抽动秽语综合征的疗效.方法将45例抽动秽语综合征患儿按随机数字表法分为针刺组(23例)和西药组(22例),针刺组选取中脘和四关穴,同时配合其他常规穴位针刺治疗,西药组口服氟哌啶醇常规治疗.结果治疗组治愈率为65.2%,西药组治愈率31.8%,两组治愈率比较差异有统计学意义(P＜0.05).结论扶土抑木法针刺治疗儿童抽动秽语综合征疗效确切.     

Research on Meridians in China

The theory of meridian （it is interpreted as channels and collaterals, or meridian in English）, is an important theoretical kernel of traditional Chinese medicine （TCM）. TCM holds that meridian is a complicated system with the fourteen meridians as the main part, which distributes over the whole human body. Each meridian belongs to a corresponding viscus interiorly, and winds around the limbs and joints exteriorly. It functions to transport the qi and blood, regulates the balance between Yin and Yang, responses to the changes in the natural world. It is the pathway for transporting qi and blood. Accordingly, it is considered to be the connective, regulative and responsive system of the body. In comparison to the Western medicine and modem biology, it elucidates the vital process and regulation of the function of human body in a totally different way and involves many brilliant theoretical expositions. Therefore, it has been deeply concerned by many researchers in China and abroad. Once the essence of meridian is elucidated, it must vigorously promote the development of TCM as well as the whole medical science and benefit the mankind.     

Therapeutic Observation on 62 Cases of Auditory Vertigo Treated by Moxibustion on Baihui

Thepaperreportsthesatisfyingeffectson62casesofauditoryvertigotreatedbymoxibustiononBaihuipointmainlycombinedwithacupuncture.1.Methods(1)Points:MainPoint:Baihui;ExtraPOints:Fengchi,Yifeng,Hegu,Taichong,Neiguan,Zusanli.(2)Moxibustion:Keepadistance1cunbetweenthekindledstandardmoxibustionbarandthescalpfor15minuteswhileturningthebaruntillthepatientsfeltwarmbutnopain.(3)UseofextraPOints:StimulateonFengchi(double)andYifeng(double)fortinnitus;Zusanli(double)andNeiguan(double)fornauseaandvomit…     

rch on hierarchical inter-connectivity am

支气管哮喘是因支气管痉挛、黏膜水肿、分泌物增多而引起支气管阻塞的疾病。笔者2001～2004年采用加味射干麻黄汤治疗支气管哮喘急性发作100例,取得较好临床效果。现报告如下。1资料与方法1.1一般资料全部患者均为门诊患者,符合1997年5月中华医学会呼吸病学分会《支气管哮喘防治指南(修订)》诊断标准。所有患者均见反复发作喘息、呼吸困难、胸闷或咳嗽,发作时双肺均可闻及散在或弥漫性、以呼气相为主的哮鸣音,呼气相延长。100例中男性67例,女性33例;年龄5～61岁,平均32岁;病程最长25年,最短3年,平均17年;该次急性发作,病程最长11d,最短3d,平…     

Study on Mechanism of Scalp Electro-acupuncture in Treating Ischemic Stroke Based on CT Localization

目的：探索一种治疗缺血性中风的有效方法。方法：利用颅脑CT定位，在对应于缺血性中风病灶的头皮区实施电针治疗，并对脑血流及血液流变学进行检测。结果：观察组的疗效、脑血流及血液流变学改变均高于对照组（P〈0．05）。结论：CT定位电头针是治疗缺血性脑中风的有效疗法。     

Observation on Therapeutic Effect of Nape Multiple Acupuncture on Vertebral Artery Type of Cervical Spondylosis

目的总结项丛刺法在椎动脉型颈椎病治疗中的作用.方法将2001年至2004年间收治的椎动脉型颈椎病的患者随机分为单纯药物治疗的对照组50例与药物治疗加以项丛刺的针药组50例进行治疗.结果与对照组相比,针药组的临床治愈率明显提高(P＜0.05).结论在椎动脉型颈椎病的治疗上药物治疗配合项丛刺治疗可明显提高疗效.     

Warm Needling Method on Rheumatoid Arthritis

目的：观察温针灸治疗类风湿性关节炎的疗效。方法：采用温针灸法治疗类风湿性关节炎患者，取关元、气海、足三里、肝俞、肾俞、脾俞为主穴，配合局部选穴及循经取穴，以单纯毫针刺法进行疗效对照。观察治疗前后RA患者关节疼痛、压痛、肿胀、功能障碍指数，握力，晨僵和20米步行时间及RF、ESR、CRP、IgG、IgA和IgM等指标。结果：温针灸能明显改善RA患者的主要临床症状，温针组与对照组的总有效率分别是86．2％、57．1％（P〈0．01）。疗效与病程、病情相关。结论：温针灸法治疗类风湿性关节炎临床疗效明显优于单纯毫针刺组，有较好的抗炎镇痛及免疫调节的作用。     

Clinical Study on Treatment of Shoulder Periarthritis with Electro-acupuncture on Point Jianyu （LI 15）

目的:比较电针肩髃穴与口服双氯酚酸钠缓释剂治疗肩关节周围炎的疗效、安全性.方法:本实验为随机对照研究,患者随机分2组,每组30例,电针组采取电针患侧肩髑穴,每次针刺20 min.治疗每日1次.对照组口服双氯酚酸钠缓释片75 mg,每日1次.所有患者治疗7 d为1个疗程,连续治疗2个疗程,疗程结束后根据疗效评定标准进行疗效评估.结果:电针组和对照组有效率分别为93.3%和56.7%.结论:电针肩髑穴是治疗肩关节周围炎有效方法.对肩关节周围炎的疗效明显优于口服双氯酚酸钠缓释片.     

Observation on the Effect of Electroacupuncture on Ischemic Cardiac Function in the Intact and Spinalized Rabbits

Ｏｂｊｅｃｔｉｖｅ　Ｔｏｏｂｓｅｒｖｅｔｈｅｅｆｆｅｃｔｏｆｅｌｅｃｔｒｏａｃｕｐｕｎｃｔｕｒｅ (ＥＡ)ｏｆ“Ｎｅｉｇｕａｎ” (ＰＣ 6) -“Ｊｉａｎｓｈｉ” (ＰＣ 5 )ｏｎｔｈｅｉｓｃｈｅｍｉｃｃａｒｄｉａｃｆｕｎｃｔｉｏｎａｌａｃｔｉｖｉｔｙｉｎｔｈｅｉｎｔａｃｔａｎｄｓｐｉｎａｌｉｚｅｄｒａｂｂｉｔｓ .Ｍｅｔｈｏｄｓ　Ｉｎｔｈｅｆｉｒｓｔｐａｒｔｏｆｔｈｅｓｔｕｄｙ,3 3ｉｎｔａｃｔｒａｂｂｉｔｓａｎｅｓｔｈｅｔｉｚｅｄｗｉｔｈｍｉｘｔｕｒｅｏｆ 2 0 %ｕｒｅｔｈａｎｅ(42 0 ｇ/ｋｇ)ａｎｄ 1 .5 %ｃ…     

Observation on the Therapeutic Effect of Shangjinbitong Powder(伤筋痹痛散) on Improving Acupoint Plaster

Objective: To study the therapeutic effect of Shangjinbitong Powder(伤筋痹痛散) on improving acupoint plaster, in order to provide some scientific basis for clinical use. Methods: This project was carried out from June 2020 to January 2021, 30 patients with low back pain in the outpatient department of orthopedics and traumatology in our hospital and 30 patients with low back pain in the rehabilitation department of Fuping County Hospital of Traditional Chinese Medicine were selected as the research ...     

Study on Brain Protective Effect and Mechanism of Yiqi Huoxue(益气活血)Method based on Wnt/β-catenin Signaling Pathway on Focal Cerebral Ischemia-reperfusion Rats

目的:观察益气活血法对局灶性脑缺血再灌注大鼠的脑保护作用,并探讨其可能作用机制.方法:建立局灶性脑缺血再灌注大鼠模型,建模成功大鼠随机分为模型组(n=17)、血塞通组(n=17)、补阳还五汤组(n=17)、联合组(n=18),另设假手术组(n=17)和空白组(n=17).各组大鼠给予相应干预.比较各组大鼠1、3、7d神经缺损评分、脑组织含水量、脑梗死体积百分比,检测脑组织无翅型MMTV整合位点家族成员3a(Wnt3a)、糖原合成酶激酶-3β(GSK-3β)、β-连环蛋白(β-catenin)、细胞周期蛋白D1(CyclinD1)、B淋巴细胞瘤-2基因(Bcl-2)、Bax的mRNA及蛋白表达情况.结果:与模型组比较,血塞通组、补阳还五汤组和联合组大鼠1、3、7d神经缺损评分、大脑组织含水量、脑梗死体积百分比、脑组织GSK-3β mRNA及蛋白相对表达量均降低(P＜0.05),脑组织Wnt3a、β-catenin、CyclinD1的mRNA及蛋白相对表达量,以及Bcl-2/Bax均升高(P＜0.05);联合组上述指标改善情况均优于血塞通组和补阳还五汤组(P＜0.05).结论:益气活血法对局灶性脑缺血再灌注大鼠具有脑保护作用,其机制与激活Wnt3a/β-catenin信号通路有关.     

Clinical Evaluation on Xiyanping Injection in the Treatment of Bronchopneumonia in Children Based on Meta‑Analysis

Objective: The aim of this study is to evaluate the effectiveness and safety of xiyanping injection (XYPI) in the treatment of children with bronchopneumonia. Methods:Asystematic and comprehensive search was conducted in the domestic and foreign electronic databases CNKI, SinoMed, VIP, WanFang DATA, PubMed, The Cochrane Library, Embase, Web of Science, Clinical?Trials.gov, and the search date ended on May 30, 2019. Inclusion criteria: (1) the types of studies included were randomized controlled trials; (2) the study participants were infants and children with a clear diagnosis of bronchopneumonia, without gender and ethnic restrictions; (3) the intervention test group was XYPI or the control group plus XYPI. The control group was routine treatment (RT) (basic treatment such as fever, cough and asthma, oxygen inhalation, anti?infection, maintaining water, electrolyte balance, etc.) or other Western medicine or RT + other Western medicine treatment. Except for XYPI, the two groups were consistent in intervention measures.According to the Cochrane Handbook, 5.1 evaluation standard and a meta?analysis of the final included studies was performed using RevMan 5.3 software. Results:Atotal of 57 studies were included, with a total sample size of 8454 cases, of which 4255 were in the experimental group and 4199 were in the control group. Meta?analysis results showed that (1) Total effective rate: XYPI group was better than the control group (relative risk [RRRT] = 1.25, 95% confidence interval [CI] [1.15, 1.36], P < 0.00001; RRRT + RBVI = 1.18, 95% CI [1.09, 1.29], P < 0.0001; RR antibiotic = 1.16, 95% CI [1.09, 1.24], P < 0.00001, RRRT + antibiotic = 1.22, 95% CI [1.16, 1.27], P < 0.00001); antipyretic time: XYPI group was better than the control group (mean difference [MDRT] = ?0.97, 95% CI [?1.17, ?0.76], P < 0.00001; MDRT + antibiotic = ?2.28, 95% CI [?2.88, ?1.67], P < 0.00001; MDRT + RBVI = ?1.51, 95% CI [?1.81, ?1.21], P < 0.00001; cough disappearing time: XYPI group was better than the control group (MDRT = ?1.37, 95% CI [?1.74, ?1.00], P < 0.00001; MDRT + antibiotic = ?1.71, 95% CI [?2.04, ?1.37], P < 0.00001; MDRT + RBVI = ?1.51, 95% CI [?2.15, ?0.86], P < 0.00001); disappearance time of lung rales: XYPI group was better than the control group (MDRT = ?1.11, 95% CI [?1.35, ?0.88], P < 0.00001; MDRT + RBVI = ?1.63, 95% CI [?2.23, ?1.03], P < 0.00001). The difference was statistically significant; (2) Of the 57 studies (a total of 8454 cases), 29 studies reported adverse reactions, of which 18 studies did not find adverse reactions, and 11 studies reported adverse reactions such as nausea, vomiting, and rash after medication in both groups. (3) The funnel chart indicated potential publication bias. Conclusion: Based on the existing clinical evidence, XYPI can have a certain effect on the treatment of children with bronchopneumonia, and it is not yet possible to conclude its safety evaluation. Moreover, due to the low quality of the included studies, this evidence is still used with cautious clinically.     

Observations on the Curative Effect of Auricular Point Sticking Therapy on Vertebral Artery Type of Cervical Spondylosis

目的：评价耳穴贴压法治疗椎动脉型颈椎病的疗效。方法：采用同期随机单盲对照方法。治疗组42例采用耳穴贴压法，对照组38例采用中成药治疗。15d为1个疗程，最多不超过2个疗程治疗。结果与结论：治疗组总有效率为97．6％，对照组总有效率为73．7％。两组比较差异有统计学意义，治疗组明显优于对照组。     

Clinical Observation on Application of Jiao Tai Pill on Shenque （CV 8） in Treating Insomnia

目的：观察神阙穴贴敷交泰丸治疗失眠症的临床疗效。方法：将152例失眠患者按就诊顺序随机分为2组,治疗组76例,采用交泰丸贴敷神阙穴治疗;对照组76例,采用口服交泰丸治疗,疗程均为4星期。于治疗前和治疗第1、2、4星期末及停药后第1、2、4星期末采用匹兹堡睡眠质量指数量表评定临床疗效。结果：治疗4星期,两组患者的睡眠质量均得以改善,组间差异无统计学意义,且无不良反应,停药后睡眠改善持续时间长。结论：交泰丸神阙穴贴敷与口服治疗失眠症疗效肯定,停药后反跳现象不明显。     

Clinical Observation on Treatment of Likang Ⅲ Combined with Thymosin on Patient with Hepatitis C-related Decompensated Cirrhosis

目的 观察利康Ⅲ号方联合胸腺肽治疗失代偿期丙型肝炎肝硬化的疗效及安全性.方法 采用随机分组的方法,将49例失代偿期丙型肝炎肝硬化患者分为两组.治疗组25例,给予利康Ⅲ号方联合胸腺肽a1治疗;对照组24例,单用胸腺肽a1治疗.分别观察两组治疗前后血清肝功能指标、丙型肝炎病毒HCV-RNA水平、肝纤维化指标及B超检查,并进行Child-Pugh评分.结果 疗程结束后,两组患者血清肝功能指标改善,Child-Pugh评分下降,HCV-RNA载量下降,肝纤维化指标下降,门静脉血流动力学指标改善,配对比较差异有显著性(P<0.05);治疗组患者肝功能、肝纤维化指标、Child-Pugh评分及门静脉血流动力学改变均优于对照组,组间比较差异有显著性(P<0.05).结论 利康Ⅲ号方联合胸腺肽a1治疗失代偿期丙型肝炎肝硬化临床疗效较好,而且安全性良好.     

Recent Advance in Study on Agarwood Formation

Highlight for Cloning and Expression Analysis on 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase from Aquilaria sinensisAgarwood is a well-known Traditional Chinese Medicine and is also widely used in perfume production.Great demand pushes agarwood to become the most expensive wood in the world.Agarwood is dark resinous heartwood of the trees from Aquilaria genus when they are wounded by wind breakage,thunder strikes,insect attack,or microorganism     

A Study on the Mechanism of the Protective Effect of GuangeFang on Sepsis‑Associated Acute Kidney Injury

Objective: The objective of this study was to explore the mechanism of? Guan Gefang (GGF) ; raw rhubarb 30 g, cassia arboreal 30 g, raw oyster 30 g, ground elm 60 g, and dandelion 30 g) kidney protection. Materials and Methods: Thirty?six Sprague Dawley rats were randomly divided into a control group (Group N), a sepsis control group (Group S), and a sepsis + GGF group (Group G). For Group N, 8 ml/kg 0.9% NaCl was used as an enema; for Group S, cecal ligation and puncture (CLP) method was used for modeling and 8 ml/kg 0.9% NaCl was used as an enema; and Group G, CLP was used for modeling and 8 ml/kg GGF was used as an enema. All of the enemas were applied once daily for 4 days. The indices of serum creatinine (SCr), blood urea nitrogen (BUN), uric acid (UA), mammalian target of rapamycin (mTOR), Janus kinase 2 (JAK2) were compared across each group. Results: Compared to Group S, Group G had lower levels of SCr, BUN, and UA(P < 0.05), while the activities of mTOR and JAK2 were significantly inhibited. Conclusion: GGF may have inhibited the JAK2 or mTOR signaling pathways to protect the rats’ kidneys, which had sepsis-associated acute kidney injury.