疾病家庭负担量表应用于晚期血吸虫病的信度和效度

目的 评价疾病家庭负担量表(family burden scale of diseases,FBS)应用于晚期血吸虫病(晚血)的信度和效度,为晚血家庭负担评价工具的选择提供科学依据.方法 在湖南省汉寿县及湖北省江陵县,以FBS作为测评工具对晚血患者家属进行入户调查,评价其应用于晚血的信度和效度.结果共调查家属318名,...     

SF-12量表评价中国老年人生存质量的信度和效度分析

目的分析SF-12量表评价老年人群生存质量的信、效度。方法采用SF-12量表对养老机构及居家养老的451名老年人进行横断面调查,分析量表的信度与效度。结果量表总的Cronbachα系数为0.775;量表8个维度的集合效度和区分效度试验成功率均为100%;因子分析提取2个公因子,累积贡献率为59.0%,其中躯体活动功能(PF)、角色功能(RP)、躯体疼痛(BP)、社会功能(SF)、情绪功能(RE)、心理功能(MH)维度与理论结果假设相符,健康总评(GH)、活力(VT)维度与量表的理论结构假不符;量表与单条目的健康自评量表的效标效度检验,相关系数r=0.776,P=0.000。结论 SF-12量表具有较好的信度与效度,适用于中国文化背景下老年人生存质量的测量。     

SF-36和EQ-5D-5L量表在晚期血吸虫病患者生命质量评价中的比较研究

目的比较健康状况调查表(SF-36)和五水平欧洲五维度健康量表(EQ-5D-5L)用于晚期血吸虫病患者生命质量评价的效果。方法选择2020年就诊于嘉兴市某两家医院的晚期血吸虫病患者为调查对象,收集患者一般情况相关信息,包括姓名、性别、年龄、晚期血吸虫病临床分型等。分别采用SF-36和EQ-5D-5L量表进行问卷调查,比较两种量表评价晚期血吸虫病患者生命质量的信度、效度以及对于不同健康程度晚期血吸虫病患者的区分程度,并对两种量表评价得分进行相关性分析,对影响晚期血吸虫病患者生命质量的影响因素进行分析。(36.80%),女性79例(63.20%);巨脾型54例(43.20%),腹水型71例(56.80%)。SF-36量表内部一致性信度Cronbach’sα系数为0.780,主成分分析法提取2个因子,累计贡献率为70.427%; EQ-5D-5L量表内部一致性信度Cronbach’sα系数为0.850,主成分分析法提取2个因子,累计贡献率为85.884%。SF-36量表各领域中,精神健康平均得分最高(66.82±7.90),生理职能和情感职能得分最低(均为0分);生理健康总测量(PCS)平均得分(33.85±8.92),心理健康总测量(MCS)平均得分(39.76±4.93); MCS得分较高的患者数为119例,多于PCS的81例。EQ-5D-5L量表中效用指数(UI)得分平均值为(0.801±0.214);"疼痛或不舒服"维度存在"中度困难、严重困难及极度困难"患者所占比例最高(占24.80%),"焦虑或抑郁"维度最低(占5.60%)。视觉模拟标尺(EQ-VAS)评分平均值为(66.64±7.85)。年龄对患者PCS、 MCS、 EQ-VAS评分影响均较大(P 0.01),不同性别、临床分型得分之间差异无统计学意义(P 0.05)。PCS、 MCS得分较高者UI得分、 EQ-VAS评分均高于PCS、 MCS得分较低者(P 0.01);在EQ-5D-5L中随着各维度严重程度的增加,患者PCS、 MCS得分降低(P 0.01)。PCS与UI得分、 EQ-VAS评分具有相关性(r=0.716、 0.689, P 0.01), MCS与UI得分、 EQ-VAS评分具有相关性(r=0.622、 0.544, P 0.01)。结论 SF-36和EQ-5D-5L量表均可用于评价晚期血吸虫病患者的生命质量,其评估效果具有可比性和互补性,但EQ-5D-5L量表因信度、效度更高且结构简单等优势,更适宜用于晚期血吸虫病患者生命质量的评估。     

多维健康评定量表在中国系统性红斑狼疮人群中的信度及效度研究

目的 评估中文版多维健康评定量表(MDHAQ-C)在中国SLE人群生活质量测量中的信度及效度.方法 招募SLE患者1 12例,信度分析采用组内相关系数(ICC)重测信度及克隆巴赫系数α内部一致性评估.聚合效度通过比较MDHAQ各维度得分与健康评定问卷(HAQ)、医院焦虑抑郁量表(HAD)及简明健康状况调查表(SF-36)的Spearman相关分析进行评估相关性评价.区分效度通过比较不同组别患者各维度得分差异进行Mann-Whitney检验进行分析.结果 在维度层面,克隆巴赫系数α分别为0.886及0.774;在条目层面,条目校正的项总计相关系数0.409～0.866.重测信度各维度组内相关系数值ICC范围0.615～0.920(P＜0.05).MDHAQ中文版大部分维度与HAQ、HAD及SF-36的相关性较好(P＜0.5至P＜0.001).针对不同疾病活动度及损伤程度的患者,MDHAQ不同维度得分差异有统计学意义(P＜0.05)区分效度.结论 MDHAQ中文版信度、效度良好,可作为躯体功能及生活质量的测评工具,用于中国SLE人群.     

SF-36量表用于老年人群信度及效度研究

目的 评价SF-36量表在老年人群的信度和效度.方法 采用多阶段抽样的方法,随机抽取海南省黎族地区的≥60岁老年人2 208人,采用访谈法填写SF-36量表.分析方法采用相关分析、信度分析及证实性因子分析.结果 量表分半信度为0.842 2;Spearman-Brown系数=0.914 3;Cronbach′s系数(α系数)除SF及MH维度外,其他维度均大于0.7;证实性因子分析(CFA)所有通径系数均有统计学意义,除9c及9h的通径系数外,其他的通径系数均大于0.5.拟合优度指数(GFI)= 0.77; χ2=11 74 2 . 63,P＜0.001,RMSEA =0.096,NFI=0.92;标准效度评价健康自评总分与量表总分相关系数r=0.726.结论 SF-36量表应用于海南省老年人群生命质量评价有较好的信度和效度.适用于老年人群生命质量的评价.     

SF-36量表用于甲亢患者生活质量测定的信度与效度评价

目的评价SF-36生命质量量表在甲亢患者中的信度和效度。方法利用面对面访谈的方式调查211名甲亢患者,用分半系数和Cronbach'sα信度系数分析SF-36信度。主成分因子分析和相关分析等方法分析效度。结果SF-36的分半系数为0.778,各领域Cronbach'sα信度系数分别为生理功能0.86,生理职能0.81,躯体疼痛0.75,总体健康0.65,活力0.16,社会功能0.96,情感职能0.77,精神健康0.42。主成分因子分析提取了6个主成分代表了量表的各个领域,与量表的结构构思基本相符。结论SF-36量表用于甲亢患者生存质量测定具有较好的信度和效度,因而具有一定的实用价值。     

SF-36量表在MDR-TB患者生命质量评估中的应用

目的 评价SF-36量表在耐多药肺结核（MDR-TB,同时耐利福平和异烟肼）患者中的适用性,并分析相关因素对生存质量的影响。 方法 用SF-36量表对100例MDR-TB患者和200名健康志愿者进行生命质量测评,评价量表的信度和效度。对完成疗程100例患者治疗前、治疗3个月及治疗1年的生命质量总评分及各维度得分进行配对t检验、多元方差分析评价疗效。对生命质量的影响因素进行单因素分析和多因素逐步回归分析。 结果SF-36量表分半信度0.96,各维度及总表的Cronbach’s а系数均大于0.7。 MDR-TB患者的生命质量总分及8个维度得分与正常对照组相比差异有统计学意义（P<0.05）;治疗3个月或治疗1年的生命质量总分及8个维度的得分明显高于治疗前且差异有统计学意义（P<0.05）;治疗1年后的总分及PF、PR、GH、VT、SF、ER、MH7个维度较对照组低并差异有统计学意义（P<0.05）。影响MDR-TB患者生命质量的主要因素是：文化程度、耐药数目、不规则治疗、Hb降低。 结论 SF-36量表适于在MDR-TB患者中运用.MDR-TB患者的生命质量均显著降低,治疗后生命质量明显提高,但治疗1年后仍不能恢复正常。影响 MDR-TB患者生命质量的主要因素是：文化程度、耐药数目、不规则治疗、Hb降低。     

肝病生存质量量表在慢性病毒性肝炎患者中的性能评估

目的:探讨肝病生存质量量表(Liver Disease Quality of Life Questionnaire,LDQOL1.0)中文版在慢性病毒性肝炎患者生存质量测试中的信度和效度.方法:使用LDQOL1.0中文版对100例慢性病毒性肝炎患者进行进行生存质量测试,回收有效问卷91例,使用克朗巴赫系数(Cronbachα)、天花板效应和地板效应来检测量表的信度;通过计算各个肝病特异性维度与S F-36的8个维度之间的相关系数来评估量表的标准效度;通过探索性因子分析来评估量表的结构效度;通过比较不同Child Pugh评分的患者的得分,评估量表的区分度.相关性检测使用Pearson相关系数,区分度检测使用方差分析进行多重比较.结果:Cronbach α在各领域中的分值为0.33(95%C I:0.08-0.52)-0.9(95%C I:0.90-0.99),80%领域分值0.7;天花板效应在0%-39.6%,地板效应在0%-34.1%,80%领域20%.标准效度提示12个肝病特异性领域里,有6个领域与SF-36的相近领域相关度较好(Pearson系数0.5,P0.05);因子分析提示肝病特异性12个领域里7个领域因子分析结果与原量表构想相似.区分度检测提示肝病特异性12个领域里7个的区分度较好(F:0.353-21.29,P0.05).结论:LDQOL1.0在中国慢性病毒性肝炎患者中测试生存质量,大部分领域信度、效度和区分度较好,可以用于临床工作.     

中文版SF-36量表用于中国老年军人生活质量调查的信度与效度评价

目的 探讨美国简明健康测量量表SF-36用于中国老年军人生活质量测量的可能性。方法 采用分层、整体抽样法，使用SF-36量表中文版对西安地区934例老年军人的生活质量进行测定，参照国际生活质量评价项目的标准程序，进行正式的心理测量学试验。结果 本次研究中，SF-36量表中文版的分半信度为0．892；同质性信度系数除社会功能、心理健康2个维度，其它6个维度变化范围为0．70～0．93，满足群组比较的要求。除社会功能、心理健康维度外，其它6个维度条目的维度相关性一致；因子分析产生的8个共因子与理论结构基本一致，结构效度的累积方差贡献为68．56％。结论 SF-36健康调查量表可用于中国老年人的调查，同时提示在精神和心理方面的个别语句经进一步修订后，将提高调查的可行性及相关方面的信度和效度。     

药物成瘾者生命质量测定量表在美沙酮维持治疗病人中的应用

目的对药物成瘾者生命质量测定量表(QOL-DA)在美沙酮维持治疗病人中应用的信度、效度和反应度进行检验。方法采用分层随机抽样的方法,调查293名美沙酮社区维持治疗门诊病人和109名社区海洛因成瘾者,采用内部一致性可信度和分半信度进行信度检验,结构效度和区分效度采用因子分析、相关分析、t检验。结果总量表及各维度Cronbach’sα系数在0.7以上,因子分析符合逻辑关系,8个公因子累计方差贡献率达62.99%,四个维度方差贡献率分别为30.221%、13.187%、8.763%、10.821%,不同性别维持治疗病人的生活质量差异有统计学意义(t=2.787,P=0.006),维持治疗病人的生活质量明显高于社区海洛因吸食者(P<0.05)。结论 QOL-DA量表具有较好的信度、效度和反应度,可用于美沙酮社区药物维持治疗病人的生活治疗评价。     

Translation and validation of the Chinese Social Role Participation Questionnaire in patients with ankylosing spondylitis

Social Role Participation Questionnaire (SRPQ) is used to evaluate the social participation with ankylosing spondylitis (AS). Although the SRPQ has English and Dutch versions, there is no Chinese version even though China has the largest population of patients with AS. The objective of our study was to translate the SRPQ into Chinese version and assess its reliability and validity in Chinese patients with AS. The C-SRPQ was developed in a five-step translation and cross-cultural adaptation procedure. A total of 105 patients with AS were recruited during the time from September 2014 to June 2017. The intraclass correlation coefficient (ICC), Cronbach’s alpha (α), and Spearman correlation coefficient (r) were used to evaluate test-retest reliability, internal consistency reliability, and the construct validity of C-SRPQ, respectively. All of the 105 patients with AS successfully completed the questionnaires. Ninety-eight patients (93.33%) participated in at least nine roles for satisfaction dimensions. No floor or ceiling effects were checked. The high value of ICC (>?0.8, 0.831–0.895) indicated the excellent test-retest reliability. In internal consistency reliability, most of Cronbach’s alpha coefficient was strong (α?≥?0.7, 0.534–0.962). In construct validity, more than half of the correlations between the dimensions of C-SRPQ and other questionnaires were good (r?>?0.6). The correlations between all dimensions of C-SRPQ and BASDAI, BASFI, and ASQoL were strong negative (P?<?0.01). There was a strong positive correlation (P?<?0.01) between all dimensions of C-SRPQ and SF-36 physical component score (SF-36PCS), SF-36 mental component role score (SF-36MCS). The C-SRPQ is a reliable and valid questionnaire to evaluate the social participation in Chinese patients with AS.     

晚期血吸虫病患者抑郁症发生率及生活质量调查

目的调查晚期血吸虫病（晚血）患者抑郁症发生情况及其生活质量。方法采用抑郁自评量表（SDS）及健康状况调查问卷（SF36）对现症晚血患者进行问卷调查,分析其抑郁症发生及生命质量状况。结果共调查356例晚血患者,收集有效问卷306份,抑郁症患病率为48.69%。抑郁症患者SF36各维度评分均显著低于无抑郁症患者（P均〈0.01）,SDS评分与SF36各维度评分呈负相关（r=-0.839～-0.182,P均〈0.01）。结论晚血患者抑郁症患病率较高,且生活质量较差。在积极救治患者的同时,应加强其心理护理。     

The reliability, validity and sensitivity to change of the Chinese version of SF-36 in oriental patients with rheumatoid arthritis

OBJECTIVE: To assess the reliability, validity and sensitivity to change of a Chinese version of the 36-item Short-Form Health Survey (SF-36) in Chinese-speaking patients with rheumatoid arthritis (RA) in Singapore. METHODS: The psychometric properties of the Chinese Hong Kong standard version of the SF-36 were assessed in 401 RA patients. The construct validity of the Chinese SF-36 was assessed by comparison with the American College of Rheumatology (ACR) functional status, a validated Chinese Health Assessment Questionnaire (C-HAQ) and markers of RA activity and severity. RESULTS: The overall Cronbach's coefficient alpha was 0.921, reflecting excellent internal consistency. The instrument showed reasonable test-retest reliability except in the social functioning (SF) subscale. There was a significant ceiling effect in the role physical (RP), SF and role emotional (RE) subscales and a floor effect in the RP and RE subscales. Physical function (PF) and SF were strongly correlated with C-HAQ and patient's assessment of RA activity [Pearson's correlation coefficient (r) ranging from -0.41 to -0.53] and moderately correlated with ACR functional status (r = -0.35 and -0.3, respectively). Weak correlations were also found between the Chinese SF-36 and markers of RA activity, deformed joint count and radiographic damage. PF and SF were the subscales most responsive to change in quality of life (QOL). CONCLUSION: The Chinese SF-36 showed reasonable reliability, criterion validity and responsiveness with limitations in certain subscales. Overall, the physical domains and PF in particular may be the most ideal psychometric measures of QOL in RA.     

Reliabilitäts-, Validitätsund Responsivitätsprüfung des Funktionsfragebogen Bewegungsapparat (SMFA-D) bei Patienten mit Coxarthrose und totalendoprothetischem Gelenkersatz des Hüftgelenkes

BACKGROUND: The aim of the present study was to check for reliability, validity and responsiveness of the Musculoskeletal Function Assessment questionnaire (SMFA-D) in patients with coxarthrosis undergoing total hip replacement. PATIENTS AND METHOD: In a prospective clinical trial the SMFA-D, the SF-36, the Harris Hip score, test of walking speed and the functional impairment according to the physician assessment were recorded. RESULTS: The reliability of the instrument could be demonstrated by a correlation coefficient of r = 0.78 for the function index and r = 0.84 for the bother index. Patients could be distinguished by the physician's assessment to show discriminative validity. Both indices correlated significantly with the Harris Hip score, scales of the SF-36 and the walking speed supporting the construct validity. The responsiveness could be shown with large effect sizes (1.04 for the function index and 1.02 for the bother index) at the three-month follow-up. CONCLUSIONS: The SMFA-D was found to be a reliable, valid and responsive instrument in patients with coxarthrosis undergoing hip replacement and the use of this instrument can be recommended.     

The reliability, validity and responsiveness of an aggregated locomotor function (ALF) score in patients with osteoarthritis of the knee

OBJECTIVES: The aggregated locomotor function (ALF) score, a simple measure of observed locomotor function, using timed walking, stairs and transfers, was developed and evaluated for intra-tester reliability, criterion-related validity and responsiveness in a sample of patients with knee osteoarthritis. METHODS: Patients with knee osteoarthritis (n = 214) were recruited for inclusion in a randomized controlled trial investigating two methods of exercise provision. Before treatment, patients completed the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Short Form 36 health survey (SF-36) questionnaires and were timed whilst performing an 8 m walk, ascending and descending a set of gymnasium stairs and completing a test of transferring in and out of a chair. A group of 15 patients also undertook a replicate test-retest reliability study of the above outcome measures. Standardized response means were calculated for the ALF, WOMAC and SF-36 from data from the clinical trial. RESULTS: The ALF takes 10 min to administer and demonstrated excellent intra-tester reliability, with excellent intra-class correlation coefficient (ICC) statistics (ICC(2,k) 0.99; 95% CI 0.98-0.99), and low standard error of measurement (0.86 s) and smallest detectable difference (9.5%) values. Criterion-related validity with the physical function dimensions of the WOMAC and SF-36 was good, with correlation coefficients of 0.59 and - 0.53 respectively. Standardized response means were higher for the ALF (0.49) than for both the WOMAC (0.39) and the SF-36 (0.12). CONCLUSIONS: This work has demonstrated that the ALF can be used as a measure of physical function status and as a means of quantifying treatment response. The measure offers a simple and convenient outcome in the assessment and treatment of locomotor dysfunction. The ALF score is a reliable, valid and responsive outcome measure over 12 months and can be recommended for use in the evaluation of patients with knee osteoarthritis.     

简短炎症性肠病生活质量问卷的信效度评价

背景简短炎症性肠病问卷(the short inflammatory bowel disease questionnaire,SIBDQ)广泛用于评估炎症性肠病(inflammatory bowel disease,IBD)患者的健康相关生活质量.目的引进SIBDQ量表并评估其信效度.方法根据Brislin模型的翻译-回译流程得到中文版SIBDQ(SIBDQ-C).对2020-06/2021-06就诊于广州中医药大学第一附属医院、中山大学第一附属医院IBD患者进行测评;使用克朗巴赫系数、分半信度和重测信度检验量表的信度,使用验证性因子分析评价其结构效度.结果共发放问卷113份,最终回收112份.SIBDQ-C的Cronbach’sα为0.90,折半系数为0.86;量表四个维度间的Spearman相关系数在0.61到0.77之间;验证性因子分析的近似误差方根、非范拟合指数、比较拟合指数、拟合优度指数分别为0.08、0.93、0.97、0.92;不同粪便形态患者的SIBDQ-C总分及各维度得分均有统计学差异(P<0.05).结论SIBDQ-C具有良好的信度及效度,可以用于临床测量我国IBD患者的生活质量.     

The German Short Musculoskeletal Function Assessment questionnaire: reliability, validity, responsiveness, and comparison with the Short Form 36 and Constant score—a prospective evaluation of patients undergoing repair for rotator cuff tear

In a prospective clinical trial, first the German Short Musculoskeletal Function Assessment questionnaire (SMFA-D) was tested for reliability, validity, and responsiveness in 23 patients with rotator cuff tears, and secondly the Short Form (SF)-36, and the Constant score were evaluated comparatively in 45 patients with rotator cuff tear undergoing open repair. Retest reliability was excellent for the functional index of the SMFA-D and satisfactory for the bother index. The SMFA-D showed good validity and responsiveness. All three instruments demonstrated significantly the positive effect of rotator cuff repair at 12-month follow-up. Using comparable scales, effect sizes were bigger with the SMFA-D than with the SF-36 and as big as the Constant score. Significant correlations of the SMFA-D indices with the SF-36 scales and the Constant score could be shown preoperatively. At 12-month follow-up, all correlations between SMFA-D indices, SF-36 scales, and Constant score function scales were still significant. We recommend use of the SMFA-D to assess changes in functional status concerning patients with rotator cuff tear undergoing open repair.This study is a project of the Rehabilitation Research Network of Bavaria funded by the German Ministry of Education and Research and the German Statutory Pension Insurance ().     

Validation of the Quality-of-Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-26) in Korean population

We aimed to evaluate the reliability and validity of the adapted Korean version of the Quality-of-Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-26). Translation/retranslation of the English version of QUALEFFO was conducted, and all steps of the cross-cultural adaptation process were performed. The Korean version of the visual analog scale measure of pain, QUALEFFO-26 and the previously validated Short Form-36 (SF-36) were mailed to 162 consecutive patients with osteoporosis. Factor analysis and reliability assessment by kappa statistics of agreement for each item, the intraclass correlation coefficient and Cronbach’s α were conducted. Construct validity was also evaluated by comparing the responses of QUALEFFO-26 with the responses of SF-36 using Pearson’s correlation coefficient. Factor analysis extracted 3 factors. All items had a kappa statistics of agreement greater than 0.6. The QUALEFFO-26 showed good test/retest reliability (QUALEFFO-26: 0.8271). Internal consistency of Cronbach’s α was found to be very good (QUALEFFO-26: 0.873). The Korean version of QUALEFFO-26 showed good significant correlation with SF-36 total score and with single SF-36 domains scores. The adapted Korean version of the QUALEFFO-26 was successfully translated and showed acceptable measurement properties and, as such, is considered suitable for outcome assessments in the Korean-speaking patients with osteoporosis.     

Validation of the Turkish version of the foot and ankle outcome score

The objective is to develop a Turkish version of the foot and ankle outcome score (FAOS) and to investigate its validity and reliability. The Turkish version of FAOS was developed after the translation and back-translation. The translated version was pretested on 20 patients with rheumatoid arthritis. Then, the Turkish FAOS was administered to 55 patients having foot and ankle problems. They were also evaluated by using the four subscales of the Turkish version of AIMS2, and the Turkish version of SF-36 questionnaire to test validity. Fifty patients filled out the FAOS for second time to determine test–retest reliability. Construct validity was investigated with use of Spearman’s rank correlation coefficient. Test–retest reliability was assessed with use of the intraclass correlation coefficient (ICC) and Cronbach’s alpha score. The psychometric properties of the Turkish FAOS were generally similar to the original FAOS. The random ICC for the five subscales ranged from 0.70 to 0.96. The Cronbach’s alpha coefficient ranged from 0.79 to 0.97. Construct validity of the FAOS was good. The Turkish FAOS correlated with the SF-36 and AIMS2 scales. The Turkish version of FAOS was valid and reliable instrument to assess the foot and ankle related problems. However, to assess its responsiveness further studies are needed.