原发多灶性腮腺多形性腺瘤1例报告及文献复习

该文通过报道1例原发多灶性腮腺多形性腺瘤患者的临床资料,并进行文献复习。此例原发多灶性腮腺多形性腺瘤发现及时,在右侧腮腺中发现两个独立存在的多形性腺瘤,病理诊断明确,手术彻底,愈后良好。原发多灶性腮腺多形性腺瘤罕见,术前影像学检查、术中详细触诊和手术方式的选择具有重要意义。     

Intraosseous pleomorphic adenoma of the mandible: report of a case and review of the literature

Salivary gland tumors constitute approximately 3% of all head and neck tumors. The most common neoplasm involving both major and minor salivary glands is pleomorphic adenoma. Salivary gland tumors are also known to develop within jawbones probably arising from ectopic salivary tissue. Pleomorphic adenomas arising within the jaws as primary central lesions are extremely rare with only a few cases reported. Clinically and radiographically these may resemble lesions of odontogenic origin. We present a rare case of intraosseous pleomorphic adenoma of the mandible mimicking a lateral periodontal cyst along with an extensive review of literature.     

Juvenile pleomorphic adenoma of the cheek: Report of a rare case and literature analysis

PurposeThe aim of this paper is to describe a rare case of children with pleomorphic adenoma in buccal minor salivary gland and present a brief review of the previous cases in the literature.MethodsResearch was conducted in the PubMed/MEDLINE/Google Scholar databases. The research was supplemented with a manual search to identify related published articles in dental journals.ResultsArticles published from 1986 onwards, in English language with full texts, were selected. Our search revealed that only 6 cases of children with pleomorphic adenoma in cheek (including pleomorphic adenoma arising from accessory parotid gland) were reported in the last 34 years. This paper also reports a case of pleomorphic adenoma on the cheek in a 10-year-old girl. The mass diagnosed with Ultrasonography was removed by wide local excision and no recurrence has been noted with a follow-up period of 14 months.ConclusionSalivary glands tumors are very rare in the pediatric age group, and rarely in minor salivary glands. Proper examination and assessment with preoperative imaging are necessary for its diagnosis. Pleomorphic adenoma should be included in the differential diagnosis of cheek lesions in young and adult patients. The possibility of late recurrences and malignant transformation should be regarded, thus prolonged follow-up is essential.     

Geographic stomatitis: review of the literature and report of five cases

Five new cases of geographic stomatitis have been presented along with data from 24 previously reported patients. For the first time, basic parameters of this disorder have been tabulated from this population. Although the earliest documented case appeared in the literature in 1955, the majority of articles has been published during the last 15 years. This increased frequency of reporting indicates a growing awareness of this rather innocuous lesion. Thus, the general practitioner is advised to become familiar with the salient features of geographic stomatitis. Prompt recognition and diagnosis of this lesion, based on the clinical findings and history, will usually mitigate the need for biopsy.     

Primary central carcinoma ex pleomorphic adenoma of the mandible: report of a rare case and literature review

We report a rare case of primary carcinoma ex pleomorphic adenoma (CXPA) of the mandible. A 13-year-old girl presented with a large mass, measuring about 30 cm in its greatest dimension, involving the mandible. She was referred to our department for surgery, and her postoperative course was uneventful; she is currently free from the disease 48 months after surgery. Primary CXPAs located centrally within the jawbones are rare with only 10 cases reported in the English and Chinese literature. This case illustrates 2 key facts regarding the diagnosis and therapy of CXPA. First, clinicians should be aware of this possibility and should emphasize the need for submission of so-called cystic lytic lesions for histopathologic analysis. Second, tumors should be excised en bloc with adjuvant postoperative radiotherapy when local recurrence and regional metastasis are suspected clinically.     

同侧腮腺多形性腺瘤合并淋巴上皮癌1例报告及文献复习

同侧腮腺良、恶性多原发肿瘤极为罕见。本文报告同侧腮腺同时性多形性腺瘤和淋巴上皮癌1例,结合文献回顾,分析腮腺多原发肿瘤临床诊治过程中应注意的问题,并提出病理诊断的必要指征。     

Cysticercosis of the oral cavity: report of five cases and a review of literature

This paper reports on five cases of cysticercosis of tongue and buccal mucosa, diagnosed on fine-needle aspiration cytology (FNAC), affecting child patients who presented between January 1994 and October 1997. Four cases presented with gradually increasing nodular swelling of the dorsum of tongue and in the fifth case the swelling was situated on the buccal mucosa of the left side. A clinical diagnosis of cysticercosis was not entertained in any of these patients, who each presented with a solitary lesion; instead, it was considered to be a benign cyst or benign tumour of salivary gland or mesenchymal tissue, before FNAC diagnosis. These lesions of the oral cavity may present first to a dentist and, in endemic areas, cysticercosis should be included in the differential diagnosis of solitary nodular lesions of the oral cavity, particularly in young individuals.     

Desmoplastic ameloblastoma in Indians: report of five cases and review of literature.

In the recent World Health Organization classification of odontogenic tumours, desmoplastic ameloblastoma has been characterized as a variant of ameloblastoma, with specific clinical, radiographical, and histological features. Till date, 145 cases have been reported in Japanese, Chinese, Malaysian, Western, and African populations, with very few cases described in Indians. Here, we report five cases in the Indian population. The male to female ratio was 3:2. The mean age at diagnosis was 33.2 years. Four of the tumours were located in the maxilla, in the anterior premolar region. The lone mandibular tumour was located anteriorly, crossing the midline. Three of the tumours had a mixed radiologic appearance with poorly defined borders. Unilocular change was seen in one of them. Two tumours presented as unilocular radiolucencies with specks of radiopacities and well-circumscribed borders. Histologically, irregular odontogenic islands, with a stretched-out 'kite-tail' appearance, were seen in a dense desmoplastic stroma. The peripheral layer of the epithelial islands was made up of flattened cells and the inner core was made up of spindle-shaped and, in some instances, squamous-shaped cells. In two cases, odontogenic epithelium in the form of follicles, typical of solid/multicystic ameloblastoma, was seen and these were typed as 'hybrid' variants. All the cases were treated by resection.     

Surgical treatment of pleomorphic adenoma of the parotid gland: report of 110 cases

One hundred benign and ten malignant pleomorphic adenomas of the parotid gland were analyzed. Follow up ranged from two to 20 years. Of 54 cases of benign pleomorphic adenoma of the parotid gland, recurrence was noted in five cases (9.2%). The five-year recurrence rate was 17.2%. Of the six malignant pleomorphic adenoma, recurrence within the first ten years took place in four patients (66.6%).     

Canalicular adenoma of the palate: case report and literature review

Canalicular adenoma is a rare benign salivary gland tumor of the oral cavity, typically located in the upper lip and buccal mucosa and infrequently found on the palate. The tumor is usually confined to soft tissue and rarely presents with bone erosion. A case of a large and locally-aggressive palatal canalicular adenoma is presented. The lesion presented herein was an asymptomatic ulcerated mass with significant bone erosion. The tumor was managed surgically with excision and reconstruction of the resulting palatal defect with a full temporalis muscle flap.     

Canalicular adenoma: report of five cases with ultrastructural observations

Canalicular adenomas from five patients were examined by light and electron microscopy. All patients were over 50 years of age; 4 of the lesions were from the upper lip, 4 were cystic, 2 showed capsular invasion and 1 was multifocal. Histopathologically there were epithelial duct-like or Canalicular structures cut at various angles and epithelial islands surrounded by hyalinized and mucinous connective tissue that contained little collagen. Ultrastructurally the epithelial islands contained many small lumina and connective tissue islands. The characteristic epithelial cell was columnar or cuboidal, extended from the lumina to the connective tissue, had almost straight lateral cell boundaries with desmosomes that predominated near the lumina, and possessed gap junctions and a small number of tight junctions. Their main cytoplasmic constituents were ribosomes, mitochondria, rough-surfaced endoplasmic reticulum and microfilaments. These findings show that canalicular adenomas are truly monomorphic and support the concept that they are derived from the cells of excretory ducts.     

Metastatic benign pleomorphic adenoma. Report of a case and review of the literature

Pleomorphic adenoma (PA), originally called mixed tumour, is the most common neoplasm of the salivary glands and is generally accepted as benign biologically. Occasionally PA may give rise to metastasis. The metastasis may develop in a PA in which a malignant transformation occurs, either arising a carcinoma in the PA (carcinoma ex-mixed tumour) or as a carcinosarcoma (so-called true malignant mixed tumour). However, very rare benign PA eventually metastasise, usually after having a previous recurrence, displaying benign histological features as well in the primary tumour as in the metastasis. These tumours have been termed metastatic PA or metastatic mixed tumours. The aim of this paper is to report one case of metastatic histological benign pleomorphic adenoma, and to consider the clinical, pathological and therapeutic consequences of these rare tumours as well as its possible causes and mechanisms for its behaviour.     

Juvenile dermatomyositis: literature review and report of a case

Dermatomyositis is a rare disease of unknown origin, which affects both children and adults. In the juvenile form, dermatomyositis is a multisystem disease, characterized by myositis; an erythematous rash over the bridge of the nose, around the eyes, and on the trunk and limbs; vasculitis; and dilatation of the capillaries in the nail beds and gum margin. Late development of calcinosis is seen in approximately two-thirds of the patients. This case describes a 5-year-old dental patient diagnosed with dermatomyositis. This article includes the clinical manifestations of dermatomyositis in the body and in the oral cavity as well as the considerations that should be taken when treating these patients.     

Transmigration of mandibular canines--a review of the literature and a report of five cases

Transmigration of the mandibular permanent canine is a rare event, the etiology of which is not clear. We present five cases of transmigrated mandibular canines together with a review of the literature, a discussion of the etiology, and the treatment options.