Liposarcoma

Using nuclear suspensions, the DNA-content of 7 bone-associated, paraffin-embedded liposarcomas and 3 lipomas were examined by means of flow cytometry (FCM) and was compared with the results of image cytophotometric measurements (ICM). Using ICM, 6 of 7 liposarcomas showed an aneuploid DNA content (86%), whereas FCM showed aneuploidy in 3 cases (43%). None of the lipomas had an aneuploid DNA-content using either method. The correspondance of the two methods was 70%. Because aneuploidy is of prognostic importance, ICM could be the method to determine the DNA content of liposarcoma.     

Liposarcoma of the hypopharynx

A case of the unusual condition of liposarcoma of the hypopharynx extending submucosally down the oesophagus in a 64 year old male is reviewed. The clinical, radiological and pathological features are presented and the role of various radiological modalities is discussed.     

Liposarcoma of the thyroid

Liposarcoma of the thyroid gland is rare with only 3 cases reported in the English literature. We present a further two patients whom we have recently treated: a 49 year old lady with a myxoid liposarcoma and a 71 year old man with a pleomorphic liposarcoma. Both underwent macroscopic excision of tumour but had positive margins, so were then treated with external beam radiotherapy. The former patient died from metastases 10 months after presentation, the latter remains alive but has developed metastatic disease on follow up at 24 months.We recommend the use of high dose radiotherapy following radical surgery as margins of excision are usually narrow in this most difficult region. The role of chemotherapy is yet to be established.     

Liposarcoma of the esophagus

Presented here is a report on an unusual liposarcoma of the esophagus. A 66-year-old-woman was treated successfully by surgical excision without removal of the esophagus. Thirty months after surgery and radiation she presented with neither complaint nor recurrence.     

Liposarcoma of the musculoskeletal system

Two hundred eleven cases with the diagnosis of liposarcoma of the musculoskeletal system were reviewed. The mean age at diagnosis was 52.9 years. The primary site was the proximal lower extremity in 52%. Myxoid-type liposarcoma was most frequent (60%). Metastasis was observed in 45%. One hundred two patients without prior treatment or distant spread at diagnosis were studied separately. Recurrence was noted in 26%. The median survival time was 7.5 years, with a 5-year survival of 59% and a 10-year survival of 45%. Significant variation in survival time was related to histologic grade, Enneking's stage, tumor size, and histologic type.     

Liposarcoma of the thyroid gland

The presumed first case of primary liposarcoma of the thyroid gland is presented, and the possible origin of this rare tumor from either mature fat cells or primitive mesenchymal cells is discussed.     

Liposarcoma of the mediastinum--a case report

A case of mediastinal liposarcoma in a 45-year-old man is reported. The patient was admitted to the hospital complaining of rhinorrhea. A large mass was found in the right thorax by chest X-ray. At thoracotomy, a tumor measuring 11.5 X 9 X 8.5 cm located in the anterior mediastinum with an extension to the pleural cavity formed in right middle and lower lobes was found and removed from the adjacent visceral pleura. The tumor had a fibrous capsule and was multinodular in external appearance. The cut surface was yellowish and gelatinous. The histological diagnosis of myxoid liposarcoma was made according to the subclassification of liposarcoma proposed by Enzinger et al.     

A Case of Liposarcoma of the Cheek

A rare case of liposarcoma of the left cheek in a 51-year-oldwoman is reported. The first biopsy specimen was indicativeof lipoma. After one year, the patient consulted us again, becauseof rapid increase in size of the tumor, and then, since malignancywas suspected, another biopsy was performed and a diagnosisof a well-differentiated liposarcoma was made. The tumor wasexcised, and radiation and chemotherapy were given in the operativecourse. After one year, no evidence of recurrence or metastasiswas observed.     

Osteomyelitis of the maxilla

Indian Journal of Otolaryngology and Head & Neck Surgery - Two cases of chronic osteomyelitis of maxilla in different age group with review of literatures are re-ported. In both cases superior...     

Liposarcoma of the larynx treated with radiotherapy

Liposarcoma of the larynx is an extremely rare malignancy. Only 18 cases have been reported in the literature. We herein report the first case of primary liposarcoma of supra-glottic larynx in a 53-years old male patient successfully treated with radiotherapy in August-September 1992. He currently remains free of the disease 4.5 years since the initial diagnosis.     

Rhabdomyosarcoma of the maxilla

A rare case of rhabdomyosarcoma of the maxilla in a female child along with a brief review of literature and its diagnostic problem is presented.     

Myxoma of the maxilla

Myxomas are benign connective tissue tumours, notorious for their aggressive behaviour and stubborn tendency of recurrence. These tumours are extremely rare in the head and neck region. One case of myxoma of the maxilla is being reported here.     

Chondro-sarcoma of the maxilla

A case of huge chondrosarcoma maxilla left in a 22 years old female is reported. Its presentation symptoms, radiological appearance, behaviour and treatment by extended maxillectomy is described. A new method of repairing floor of the orbit is reported.     

Ameloblastoma of the maxilla

Ameloblastoma or Adamantinoma arises from the epithelium of the Odontogenic tissue. Although it commonly involves the mandible, it is an unusual tumour of the maxilla.     

Haemangioma of the maxilla

By 1973, only twelve cases of haemangiomas of the maxilla had been reported in the literature (Sawhney et al, 1973) Another case is being reported here.     

脂肪肉瘤及其治疗

脂肪肉瘤是最多见的软组织肿瘤,其临床表现、病理和分子特征多种多样.手术治疗仍然是治疗的基础,是惟一提供治愈可能的方法.分子生物学的发展,相关分子通路、癌基因及抑癌基因等的发现,使靶向药物治疗脂肪肉瘤在将来变为可能.     

Ameloblastic fibro-odontoma of the maxilla

A rare case of Ameloblastic Fibro- Odontoma in a one year old child involving the maxilla is being reported. The tumor appeared to be of hamartotmatous origin rather than neoplastic osontogertic lesion.     

Post-irradiation fibrosarcoma of the maxilla

A Case of radiation induced fibrosarcoma of the maxilla following irradiation of a nasopharyngeal carcinoma is presented.     

Giant Ulcerated Pleomorphic Liposarcoma of the Chest Wall

Liposarcomas most often originate in the extremities and on the retroperitoneum. Primary malignant soft-tissue sarcoma of the chest is a rare entity. Most of them are low grade, and complete surgical excision is the preferred therapeutic choice. Like most cancers, the incidence of liposarcoma increases with advancing age, and subtotal resection is considered a palliative surgical procedure. The benefit of adjuvant radiotherapy or chemoradiotherapy for these tumors remains controversial.