An unusual foreign body (Big Metallic Nut) in the nasopharynx of an infant

Foreign body in the nasopharynx is an extremely rare conidition; however a big metallic nut in the masopharynx of an infant of eight- months has not been previously reported in literature. We report an unusual case where an eight-month-old child introduced a big metallic nut through the mouth and was lodged in the nasopharynx, with a brief review of literature regarding the diagnosis and management of such case.     

Secondary pharyngeal tuberculosis

Secondary tuberculosis of pharynx is a rare condition as pharynx is not a common site for clinically manifest tuberculosis. A rare and unusual case of secondary oropharyngeal tuberculosis in a 40 years male patient, who presented with an ulceroproliferative lesion of oropharynx extending to nasopharynx and laryngopharynx is being reported.     

Muco-Epidermoid carcinoma of the nasopharynx

A rare case of mucoepidermoid carcinoma of the nasopharynx is reported. The salient features of the disease are discussed in the light of available literature.     

Primary clear cell carcinoma of the nasopharynx： a case report

Primary dear cell carcinoma of the nasopharynx is a rare and locally invasive minor salivary gland neoplasm, only two cases have been reported yet in the literature. Now a 57-year man, with primary nasopharyngeal clear carcinoma,received radiotherapy and chemotherapy. After treatment, the mass of nasopharynx visibly reduced. Follow-up two months and repeated MRI, CT, abdominal B-ultrasonograpy, electronic nasopharyngoscopy, no tumor recurrence or metastasis.     

Nasopharyngeal Foreign Body in an Young Child

A number of articles on foreign body (FB) ingestion and inhalation have been reported in the literature. Of these, reports of foreign bodies lodging in nasopharynx after inhalation/ingestion are rare. A case of FB inhalation/ingestion presented with history of respiratory distress was admitted for suspected FB bronchus and kept for observation. On examination the child was not distressed and chest examination and X-ray were normal. After 2 days, however, X-ray nasopharynx was taken for rhinorrhoea, nose block and snoring since admission. A large metal nut was found in the roof of the nasopharynx. This case is reported for its rarity, unusual presentation and misleading history.     

Adenoid cystic carcinoma of the nasopharynx: a case report]

Nasopharyngeal adenoid cystic carcinoma is a rare tumor, few cases have been reported in the literature. The aim of this report is to present a new case of an adenoid cystic carcinoma of the nasopharynx. We report the case of a 50 years-old woman presenting with an adenoid cystic carcinoma of the nasopharynx with diffuse pulmonary metastasis. The treatment combined chemotherapy, based on cisplatin and adriamycin drugs, and palliative radiation therapy at the dose of 30 Gy. The patient died 6 months after diagnosis establishment. The best treatment of adenoid cystic carcinoma is complete surgical resection but extended resection can be difficult in some locations as nasopharynx. The adjuvant radiation therapy seems to improve local control.     

Rhabdomyosarcoma of nasopharynx

Rhabdomyosarcoma is a highly invasive malignant tumour arising from the mesenchymal tissue. Here, we reported a rare case of embryonal rhadomyosarcoma of nasopharynx with extension to different spaces of base of skull and orbit. Rarity of the case difficulty in diagnosis encourages its reporting.     

Nasopharyngeal rhabdomyosarcoma

Nasopharyngeal Rhabdomyosarcama, a common soft tissue sarcoma in children, is a rare identity, only four cases so far have been reported as per the review of literature. Ours is the fifth case presented exclusively in the nasopharynx, which is reported, hereby. The prognosis of this clinical entity is always gloomy and the modality of thr treatment is always surgery, chemotherapy and radiotherapy.     

Sarcoma botryoides of the nasopharynx

Malignant neoplasms of the nasopharynx other than carcinomas are rare. About 98% of the malignant lesions in this region are carcinomas and adults are more commonly affected (Batsakis, 1974). A case of nasopharyngeal malignancy of mesodermal origin in a child is reported.     

Primary lymphoepithelioma-like carcinoma of the lung

Lymphoepithelioma is an undifferentiated carcinoma with prominent lymphoid stroma in the nasopharynx. Tumors with similar histology have been reported with other localizations, including the lungs, and are designated as lymphoepithelioma-like carcinomas (LELC). Primary LELC of the lung is very rare, and scant information is available in the scientific literature. This paper details the case of a 25-year-old Caucasian male patient with the diagnosis (determined by thoracotomy) of primary LELC of the lung. Immunohistochemical analysis was negative for Epstein-Barr virus, as was the in situ hybridization of the tumor cells. Observation of the nasopharynx and a magnetic resonance image of the cavum were normal. Because the tumor (T4N2M0) could not be resected, the patient was treated with chemotherapy, carboplatin/5-fluorouracil, completing two cycles. The patient's condition worsened when he developed contralateral pneumonia, which was then followed by pericardial effusion. The patient died 36 h later from cardiac tamponade. Presented here is a revision of this rare pathology, not often reported in the literature.     

Chondrosarcoma of the nasopharynx

Chondrosarcoma of the nasopharynx is a rare entity, only four cases having been reported in the world literature to date one each by Wirth and Shimkin (1943), Timmis (1959) and Serba (1966) and Singh and Seth (1972). This paper adds a fifth case to the literature.     

Extranasopharyngeal angiofibroma arising from the infratemporal region

Angiofibroma is a histologically benign but locally invasive tumour of the blood vessels characterized by architecturally irregular vessels set in a fibrous stroma. The commonest site for occurrence of these tumours in the body is the nasopharynx. It is rare to find extranasopharyngeal origin of angiofibromas. The infratemporal fossa is a very rare site of extra nasopharyngeal angiofibroma with only 4 cases reported in the literature. We report here a case of a vascular mass arising from the infratemporal fossa of a 13-year-old boy that was confirmed to be a case of angiofibroma histopathologically. A review is also made of the other reported cases of angiofibroma arising from the infratemporal fossa. The likely theory of origin of the tumour and its management is also discussed.     

鼻咽粘液表皮样癌(附1 2例临床分析)

背景与目的:鼻咽粘液表皮样癌是鼻咽原发腺癌的一种类型,非常少见,鲜有单独报道。本研究拟对在我院治疗过的鼻咽粘液表皮样癌病例的发病、临床情况、治疗效果进行总结分析。方法:回顾性分析1975年1月至2003年12月在我院经过病理确诊和治疗的鼻咽粘液表皮样癌患者共12例的临床资料,分析其发病特点、临床治疗效果。结果:本组病例仅占同时期我院鼻咽癌患者总数的0.26‰,发病年龄为20～60岁,男女比例为2∶1。EBV血清学检查(VCA-IgA,EA-IgA,DNA酶中和率)阳性率均较低。有随访资料的11例患者中,单纯放疗4例,手术 放疗4例,放疗 化疗3例。本组患者的5,10年生存率分别为27.3%及9.0%,疗效较差。结论:鼻咽粘液表皮样癌是鼻咽癌的一种特殊类型,有其特有的发病规律,放化疗疗效较差,治疗上可能应采取以局部彻底切除为主的综合治疗为宜。     

Panhypopituitarism resulting from Hodgkin's disease of the nasopharynx

Nasopharyngeal involvement by Hodgkin's Disease is rare and may result in deafness, headaches, nasal obstructions and other symptoms. Compression of the pituitary gland with resultant panhypopituitarism has not been reported in nasopharyngeal Hodgkin's Disease. This paper documents a patient in whom Hodgkin's Disease of the nasopharynx eroded the bony sella turcica and compressed the pituitary gland causing anterior pituitary insufficiency. The patient presented with a skull x-ray and history compatible with a pituitary neoplasm. The diagnosis was established only by surgical exploration.     

Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. XIV: Chordomas

Twenty cases of a rare tumor, chordoma involving the nasal cavity, paranasal sinuses, or nasopharynx, are reported. Patients most often had localized headache, nasal obstruction, decreased hearing, or symptoms related to cranial nerve involvement, especially diplopia. A mass bulging into the nasopharynx, posterior nasal cavity, or pharynx was found on physical examination in 13 of these 20 patients, and in another 6 patients on radiologic examination. Paralysis of one or more cranial nerves was identified in the majority of patients who had tumors involving the upper nasopharynx. On radiologic examination, bone destruction was frequently identified in the clivus and sphenoid areas, and less commonly in the cervical vertebrae. Each patient had biopsy-proven tumor in the nasopharynx or sphenoid areas. Patients usually were treated by combinations of surgery and radiotherapy, in some cases leading to prolonged periods of apparent tumor control. Radiotherapy frequently resulted in regression of symptoms, sometimes lasting many months or years. A few tumors that involved mainly the lower nasopharynx were more amenable to surgical resection, in one case leading to apparent tumor control. In those cases with adequate follow-up information, most patients had either died of their disease or were living with recurrent or persistent inoperable tumor. Some patients lived for many months or years between recurrences or with known tumor, indicating that chordomas often are slowly growing neoplasms. The histologic features of these chordomas are described and illustrated, and the histopathologic differential diagnosis is discussed.     

Extranodal manifestation of Rosai Dorfman Disease of the nasopharynx

The aim of presenting this case is to highlight the fact that extranodal manifestation of Rosai Dorfman Disease (RDD) without lymphadenopathy was seen in a teenaged girl with recurrent episodes of epistaxis, due to a lobulated mass in the nasopharynx, which mimicked malignancy. This case is a rare presentation because the extranodal manifestation of RDD in multisystem organs are reported in literature, but the nasopharyngeal manifestation without lymphadenopathy is unique. The clinical presentation and surgical management of the case by endoscopic sinus surgery, the aetiopathology, differential diagnosis and review of literature are described here.     

Angiofibroma arising from nasal septum in adult male—A rare occurence

Angiofibroma is an unique problem faced by the otolaryngologist, due to its recurrence, occurence in a rather inaccessible area and troublesome bleeding during excision. It’s commonly known to arise from nasopharynx in adolescent males but extra nasopharyngeal extensions are not uncommon. Herewith we are presnting an extremely rare case of angiofibroma arising from the nasal septum in an adult male. To the best of our knowledge septal angiofibroma has not been reported in the relevant literature yet. The clinical features and management of this case are discussed in this paper.     

Chondrosarcoma of the oropharynx

Primary cartilaginous tumour in the nasopharynx and oropharynx is extremely rare. One such case in a young soldier of twenty eight years of age has been presented.     

Osteoclastoma of the nasopharynx

Osteoclastoma involves the long bones of the extremities and some of the flat bones such as the sacrum, mandible patella and vertebrae. Eggston and Wolff (1947) mentioned the possibility of its origin from bones of the upper jaw, ethmoid and sphenoid sinuses. Amongst the skull bones, Rosenwasser (1969) described a case of giant cell tumour of the middle ear, yet such a tumour arising from the nasopharynx and sphenoid seems to be extremely rare. A rare case of osteoclastoma of the nasopharynx with extensive local invasion, multiple cranial nerve involvement and fatal termination is described. The differential diagnosis and histological features have been discussed.     

Tuberculous Otitis Media and Lupus Vulgaris of Face: An Unusual Association

Tuberculous otitis media is a rare extra-pulmonary presentation of tuberculosis. Tuberculous otitis media is usually associated with pulmonary tuberculosis or tuberculosis involving nasopharynx and oropharynx. Lupus vulgaris is the most common morphological variant of cutaneous tuberculosis. The disease often affects the face and may be associated with nasal or nasopharyngeal tuberculosis. Lupus vulgaris associated with tuberculous otitis media is not reported in English literature. We report a case of 40 year old female patient who presented with symptoms of chronic suppurative otitis media and non-healing skin lesion of face. The biopsy of skin lesion showed granulomatous pathology and helped us to reach a diagnosis of tuberculous otitis media.