Glisson蒂横断式肝切除术10例报告

目的总结应用Glisson蒂横断式肝切除术的经验。方法回顾性分析10例行Glisson蒂横断式肝切除术病人的临床资料,其中肝胆管结石7例,胆囊癌1例,肝癌2例。采用Glisson蒂横断式技术分别行右肝后叶切除术(Ⅵ+Ⅶ段)3例,右肝前叶(Ⅴ+Ⅷ段)切除1例,左外叶(Ⅱ+Ⅲ段)切除2例,Ⅲ段切除1例,左半肝(Ⅱ+Ⅲ+Ⅳ段)切除2例,局部肝切除(Ⅳb+Ⅴ段)1例。结果本组病例均成功实施Glisson蒂横断式肝切除术,术中无肝蒂Glisson鞘内管道损伤。手术时间平均4.6(3.2～6.5)h,术中失血量平均440(150～800)ml。术后无严重手术并发症和死亡病例,均痊愈出院。结论 Glisson蒂横断式肝切除术的理论基础在于对肝脏解剖分段新的认识,其操作简单、快速、安全,值得普遍推广应用。     

Glisson蒂横断式肝切除术的临床应用体会

采用Glisson蒂横断式肝切除术治疗肝癌患者,总结Glisson蒂横断式肝切除术在肝癌手术切除中的临床经验.所有患者术中均无Glisson蒂内管道损伤及难以控制的大出血,术后无严重并发症和死亡病例,所有患者顺利出院.Glisson蒂横断式肝切除术作为解剖性肝切除术的一种方法,可提高肝癌手术的安全性,降低手术的风险.     

肝蒂横断法解剖性肝段切除治疗肝癌的临床研究（附36例报告）

目的总结肝蒂横断法解剖性肝段切除治疗肝细胞肝癌（肝癌）的安全性及疗效。方法回顾性分析2009年6月至2011年2月我们应用肝蒂横断法解剖性肝段切除治疗36例肝细胞肝癌患者的临床资料。结果36例肝癌患者均顺利完成肝蒂横断法解剖性肝切除,无术中死亡。术中平均出血量为320ml（80～1000m1）,其中80．5％（29／36）不需输血。肿瘤平均最大直径7．6cm（3～20cm）。术后30d内无手术死亡,术后并发症发生率为20％,无出血、肝功能衰竭等严重并发症。术后平均住院时间12d,1年复发率为13．8％,1年生存率为86．1％。结论肝蒂横断法解剖性肝段切除术治疗肝癌安全可行,提高了手术根治率。该方法简单,易于掌握,无需使用昂贵的特殊器械,值得推广应用。     

利用吲哚菁绿荧光显像技术的腹腔镜下Glisson蒂横断式解剖性肝段切除

目的探讨利用吲哚菁绿荧光显像技术的腹腔镜下Glisson蒂横断式解剖性肝段切除的效果及安全性。方法回顾性分析四川大学华西医院肝脏外科收治的1例利用吲哚菁绿荧光显像技术的腹腔镜下Glisson蒂横断式解剖性肝段切除治疗的肝细胞肝癌患者的术前临床资料、手术治疗过程及术后情况。结果结合患者术前病史、影像学及实验室检查结果考虑诊断为肝细胞肝癌,术中探查发现肿瘤只有1个,位于Ⅳ段且较表浅,遂利用吲哚菁绿荧光显像技术行Glisson蒂横断式解剖性肝段切除术,术后病理诊断符合肝细胞肝癌,无严重并发症发生,恢复良好,随访至今6个月未见复发。结论利用吲哚菁绿荧光显像技术的腹腔镜下Glisson蒂横断式解剖性肝段切除术可被作为一种用以解决手术过程中出血、肿瘤边界难确定、手术切缘是否有残余肿瘤等问题的安全、精准的治疗手段。     

Glisson蒂横断联合肝静脉阻断在肝切除术中的应用

目的探讨Glisson蒂横断联合肝静脉阻断术在肝脏手术中的运用。方法回顾性分析我院2009年1月至2011年12月20例采用Gllsson蒂横断联合肝静脉阻断术行肝脏切除患者的资料。结果其中解剖性肝切除15例,非解剖性肝切除5例。包括左外叶切除（Ⅱ＋Ⅲ）3例,左半肝切除（Ⅱ＋Ⅲ＋Ⅳ）8例,右前叶切除（Ⅴ＋Ⅷ）2例,右后叶切除（Ⅵ＋Ⅷ）1例,右半肝切除（Ⅴ＋Ⅵ＋Ⅶ＋vm）1例,局部剜除5例。20例肝脏手术中解剖性肝切除占75％（15／20）,非解剖性占25％（5／20）,平均手术时间220（120～380）min,平均失血量300（100～600）mL,术后并发胆瘘1例,经保守治疗后好转。结论Glisson蒂横断联合肝静脉阻断肝切除术能够最大限度的减少肝脏出血,保护残肝功能,提高术后患者的预后。     

Glisson蒂横断式肝切除在解剖性肝切术中的应用

目的 探讨Glisson蒂横断式肝切除在解剖性肝切除中的应用。方法 2009年6月至2012年6月间我院同一手术组使用Glisson蒂横断式肝切除方法切除肝细胞性肝癌（HCC）45例,回顾性分析其围手术期的相关临床资料,并进行1年的随访。结果 45例患者中行解剖性肝切除占82.2%（37/45）,在行三个主要肝蒂套带过程中发生胆漏、出血共6例,均以局部压迫或妥善缝合处理;术后1年肿瘤复发率15.6%（7/45）;术后1年生存率为80.0%（36/45）。结论 Glisson蒂横断式肝切除体现区域性肝门阻断特点,避免肝门部脉管分别解剖的繁琐,符合肿瘤根治的原则,具有精准肝切除的优点。     

腹腔镜下Glisson蒂横断法肝段切除策略

目的探讨腹腔镜下Glisson蒂横断法肝切除术的可行性和技术要点。方法回顾性分析2015年5月至2016年11月期间实施腹腔镜下Glisson蒂横断法肝切除术共23例。详细描述从Ⅱ段到Ⅷ段肝切除的技术要点,并观察手术时间,术中出血量,住院时间,术后并发症,近期疗效的指标。结果 23例患者接受腹腔镜下Glisson蒂横断法肝切除,其中Ⅱ、Ⅲ、Ⅴ、Ⅵ、Ⅶ段肝切除各2例、左半肝切除3例、右半肝切除3例、左外叶5例、右后叶2例。主要技术要点均为肝门部肝蒂解剖。手术均获得成功,没有中转开腹病例。平均手术时间[195.4±135.4(45~300)]min,术中平均出血量[216.7±89.4(150~300)]ml,均无输血,术后平均住院时间[5.0±1.6(3~7)]d,无手术并发症,随访早期无肿瘤复发和转移。结论腹腔镜下Glisson蒂横断法肝切除术安全可行,具有手术时间短,创伤小等优点,可在很大程度上简化了腹腔镜肝段切除。     

肝蒂横断法解剖性肝段切除术患者的围术期护理

目的探讨肝蒂横断法解剖性肝段切除术治疗肝癌的围术期护理方法。方法对68例肝癌患者采取肝蒂横断法解剖性肝段切除术,同时做好术前准备,术后密切监护病情变化及并发症的护理。结果所有患者成功切除肿瘤,手术顺利,无术中死亡。术后并发症发生率为20.6%,1例术后出血及1例胆漏的患者再次开腹手术,其余均经保守治疗治愈。平均住院15.6d。结论肝蒂横断法解剖性肝段切除术可提高肿瘤切除率,细致的护理可提高手术成功率,降低术后并发症的发生率。     

Glisson蒂横断式解剖性肝切除120例治疗体会

目的探讨Glisson蒂横断式解剖性肝切除术的应用价值。方法回顾性分析临沧市人民医院2014年1月至2017年3月行Glisson蒂横断式解剖性肝段切除术120例患者的临床资料。其中原发性肝癌65例,胆管细胞癌4例,肝门部胆管癌4例,胆囊癌6例,肝内胆管结石33例,肝血管瘤8例,肝寄生虫病10例。采用Glisson蒂横断式解剖性肝切除Ⅰ段切除3例,Ⅰ+Ⅱ段切除1例,Ⅰ+Ⅱ+Ⅲ+Ⅳ段切除1例,Ⅰ+Ⅱ+Ⅲ+Ⅳ+Ⅴ+Ⅷ段切除1例,Ⅱ+Ⅲ+Ⅳ+Ⅷ段切除1例,Ⅱ+Ⅲ+Ⅴ+Ⅵ+Ⅶ+Ⅷ段切除1例,左外叶(Ⅱ+Ⅲ段)切除33例,左半肝(Ⅱ+Ⅲ+Ⅳ段)切除22例,左三叶(Ⅱ+Ⅲ+Ⅳ+Ⅴ+Ⅷ段)切除3例,Ⅳb+Ⅴ段切除6例,Ⅳ+Ⅴ+Ⅷ段切除3例,右半肝切除(Ⅴ+Ⅵ+Ⅶ+Ⅷ段)25例,右三叶切除(Ⅳ+Ⅴ+Ⅵ+Ⅶ+Ⅷ段)3例,右前叶(Ⅴ+Ⅷ段)切除5例,Ⅵ段切除2例,右后叶切除术(Ⅵ+Ⅶ段)4例,Ⅶ段切除2例,Ⅷ段切除4例。其中9例同时行肝管空肠RouxY吻合术。结果全组均完成手术。术中平均出血量630 mL。平均手术时间3.7 h。术后发生并发症34例(28.33%),为胆漏、胸腔积液、多重耐药菌感染等。结论 Glisson蒂横断式解剖性肝切除术操作简便,快速安全,能明显减少出血,提高疗效,是一种可选择的手术方式。     

Glisson蒂横断法在腹腔镜左肝段切除术中的应用

目的:探讨应用Glisson蒂横断法行腹腔镜左肝段切除术的可行性及技术要点。方法:回顾分析2015年1月至2016年10月为14例患者行腹腔镜下Glisson蒂横断法左肝段切除术的临床资料。观察手术时间、术中出血量、住院时间、术后并发症、近期及远期疗效等指标。结果:14例患者均成功施行腹腔镜下Glisson蒂横断法左肝段切除术,无一例中转开腹,其中肝左外叶切除5例、左半肝切除4例,Ⅱ、Ⅲ段肝切除各2例,Ⅳ段肝切除1例。手术时间100~240 min,平均(140.6±89.3)min;术中出血量150~300 ml,平均(200.5±95.7)ml;住院5~10 d,平均(7.8±2.4)d;无手术并发症发生,随访早期无肿瘤复发与转移。结论:腹腔镜下Glisson蒂横断法左肝段切除术的优势在于迅速、精确的到达Glisson蒂左肝段分支,适于左半肝、左外叶及Ⅱ、Ⅲ、Ⅳ段的肝肿瘤,手术安全、可行,可在很大程度上简化腹腔镜肝段切除术。     

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??Application of Glissonean pedicle transection method for hepatic segmentectomy in the treatment of hepatocellular carcinoma: an analysis of 15 cases LUO Zhi-qiang, SHAO Jiang-hua, WU Lin-quan, et al. Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China
Corresponding author: SHAO Jiang-hua, E-mail: shao5022@163.com
Abstract Objective To report the clinical application experience of Glissonean pedicle transection method for hepatic segmentectomy in hepatocellular carcinoma. Methods The clinical data of 15 cases of hepatocellular carcinoma in different segments performed Glissonean pedicle transection method for hepatic segmentectomy from February 2010 to August 2010 in the Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Nanchang University were analyzed. Results Anatomical hepatic segmentectomy was completed in all 15 cases successfully. The average operation time was 130 (100-180) min and the average blood loss was 180 (80-320) mL. There was not blood transfusion during operations and any complications after operations in all cases. Conclusion Glissonean pedicle transection method for hepatic segmentectomy is a kind of the perfect operation method of anatomical hepatic segmentectomy, which is convenient, fast and safe to perform.     

Hepatic resection using a liver-hanging maneuver and Glissonean pedicle transection for hepatocellular carcinoma in a patient with situs inversus totalis: report of a case

Situs inversus totalis is a rare congenital anomaly in which the major abdominal organs are located as a mirror image of their normal positions. This poses much difficulty for surgeons. We describe how we performed the liver-hanging maneuver (LHM) for hepatocellular carcinoma (HCC) in a 59-year-old man with situs inversus totalis, to resolve the difficulty of the mirror-image location of his liver. The HCC was located in the right lateral sector. Although segmentectomy of segment 7 would normally be considered minimal for a curative treatment of HCC, this was relatively complicated in this patient. Thus, we performed an extended right lateral sectionectomy using the LHM to achieve a simple transection. The hepatic hilum was dissected using the Glissonean pedicle transection method. The operation time and intraoperative blood loss were 6 h 45 min and 471 ml, respectively. No blood product transfusion was required. The LHM and the hilar Glissonean pedicle approach proved effective for resolving the difficulties of performing surgery in a mirror image for HCC in a patient with situs inversus totalis.     

Glisson蒂横断式腹腔镜肝切除术：附18例报告

目的：探讨Glisson蒂横断式在腹腔镜左半肝及肝左外叶切除术的可行性与安全性。 方法：回顾性分析2011年1月—2013年6月期间18例行腹腔镜下Glisson蒂横断式肝切除术患者的临床资料。 结果：18例患者均成功实施腹腔镜下Glisson蒂横断式左半肝或左外叶肝切除术,无中转开腹。手术时间为42~300 min,平均（215.6±56.6）min;术中出血量为50~200 mL,平均（118.6±50.5）mL,均未输血;住院时间为（8~16）d,平均（11.4±3.1）d,无并发症发生。所有患者随访3~24个月,生存情况均良好,其中6例肝细胞癌患者未见肿瘤复发。 结论：Glisson蒂横断术能够有效控制出血,在腹腔镜解剖性左半肝或左外叶肝切除术中是安全可行的。

     

Glissonean pedicle transection method for hepatic resection: A new concept of liver segmentation

A new concept of hepatic segmentation along with the Glissonean pedicle tree, and the basis of hepatic resection by the Glissonean pedicle transection method are presented. The portal triad continues from the hepato-duodenal ligament to the intra-hepatic portion as the Glissonean pedicle. That is, the artery, portal vein and bile duct, together with connective tissue, are sheathed by the peritoneum to form a fibroid bundle. The entire length of the primary branches of the Glissonean pedicle and the origin of the secondary branches are located outside the liver and the trunks of the secondary and more peripheral branches run inside the liver. The ramification pattern of the tertiary branches which branch out from each secondary branch is different from patient to patient. The liver is nourished by the secondary branches of the Glissonean pedicle. Each secondary branch feeds one segment. The liver can thus be separated into three segments and an additional caudate area. The area fed by each one of the tertiary branches is cone-shaped; fermed a "cone unit". Each segment conists of six to eight cone units. In limited resections, the number of cone units to be respected is adjusted and the tertiary branches which feed these areas must be transected selectively through a hilar or a parenchymal approach. To date we have experienced no complications with this procedure, employed for 832 patients with hepatocellular carcinoma. Received for publication on March 25, 1998; accepted on March 25, 1998     

Anatomic Liver Resection of Segments 6, 7, and 8 by the Method of Selective Occlusion of Hepatic Inflow

Anatomic liver resection not only enables enough tumor-free resection margin but also guarantees maximum preservation of remaining normal liver tissue. We report herein a hepatocellular carcinoma patient who underwent successful anatomic liver resection of segments 6, 7, and 8 by the method of selective occlusion of hepatic inflow. Multiple tumors were found in segments 6, 7, and 8 by computed tomographic (CT) scanning. CT volumetry analyzed that his left hemi-liver volume was less than the minimal limit of safe survival. Therefore, we planned to perform segment 5 remaining, anatomic liver resection of segments 6, 7, and 8 to guarantee the maximum preservation of remaining normal liver tissue. Selective occlusion of hepatic inflow was creatively used twice in this case to divide right hemi-liver Glissonean pedicle and segments 6 and 7 Glissonean pedicle, respectively. Thus, the resection line was determined, and anatomic liver resection of segments 6, 7, and 8 was completed. Selective right hemi-liver Glissonean pedicle occlusion was used, while parenchymal transection was between segments 6 and 5 and between segments 8 and 5. Therefore, liver ischemia reperfusion injury and homodynamic instability were maximally reduced during operation.     

Glisson蒂横断法与Pringle法在肝细胞癌肝切除术中的应用效果Meta分析

背景与目的:Glisson蒂横断法与Pringle法在肝细胞癌(简称肝癌)肝切除术中的应用效果目前尚无一致结论,亦无大样本量的多中心研究予以证实.本研究通过Meta分析方法评价两种方法在肝癌肝切除术中的应用效果,以期在肝切除术术中阻断方式的选择上提供参考.方法:计算机检索中、英文数据库,检索时间为数据库建立至2021年...     

Laparoscopy-assisted hepatic lobectomy using hilar Glissonean pedicle transection

Although many reports have described laparoscopic minor liver resections, major hepatic resection, including right or left lobectomy, has not been widely developed because of technical difficulties. This article describes a new technique for performing laparoscopy-assisted right or left hepatic lobectomy using hilar Glissonean pedicle transection. Laparoscopic mobilization of the right or left hepatic lobe is performed, including dissection of the round, faliciform, triangular, and coronary ligaments. The right or left Glissonean pedicle is encircled and divided laparoscopically. A parenchymal dissection is then performed though the upper median or right subcostal incision, through which the resected liver is removed. We successfully performed this procedure in 6 patients without blood transfusion or serious complications. Laparoscopy-assisted hepatic lobectomy using hilar Glissonean pedicle transection can be feasible and safe in highly selected patients.     

Glisson蒂横断式原位肝切除在肝细胞癌治疗中的应用

目的 探讨Glisson蒂横断式原位肝切除在肝细胞癌外科治疗中的价值.方法 回顾性分析2011年1月至2014年3月由同一医疗组手术治疗的71例肝细胞癌病人的临床资料,其中行Glisson蒂横断式原位肝切除37例,常规肝切除术34例.结果 两组病人均无肝性脑病出现,两组手术时间、术后1年内死亡率及术后腹腔出血结果差异无统计学意义（P＞0.05）;Glisson组术中出血量（325.7±32.60） ml,顽固性腹水2例,胆汁漏1例,肿瘤切缘阳性1例术后第3天及第7天ALT、ALB、TBIL及术后住院日（10.95±0.3592）d均优于传统组,结果差异有统计学意义（P＜0.05）.结论 Glisson蒂横断式原位肝切除术较常规肝门阻断式肝切除出血量少,更容易确定肝切除界面,术后肝功能恢复快,胆汁漏及切缘肿瘤阳性率低,可缩短病人平均住院日,而未明显延长手术时间.