In vivo fluoroscopic analysis of fixed-bearing total knee replacements

In vivo kinematic patterns were determined for subjects (patients participating in the study), having either a fixed-bearing posterior-stabilized or posterior cruciate-retaining total knee arthroplasty. While under fluoroscopic surveillance, subjects did normal gait and a deep knee bend. Video images were downloaded to a workstation computer and analyzed in three dimensions using an iterative model-fitting approach. Femorotibial contact paths for the medial and lateral condyles, axial rotation, and condylar lift-off were determined. During a deep knee bend, subjects having a posterior-stabilized total knee arthroplasty routinely experienced posterior femoral rollback of their lateral condyle and normal axial rotational patterns, whereas random subjects having a posterior cruciate-retaining total knee arthroplasty experienced paradoxical anterior sliding and opposite axial rotational patterns. During gait, posterior-stabilized and posterior cruciate-retaining total knee arthroplasties experienced similar kinematic patterns, with the presence of paradoxical sliding and opposite axial rotational patterns. Subjects having posterior-stabilized and posterior cruciate-retaining total knee arthroplasties experienced condylar lift-off. Subjects having a posterior cruciate-retaining total knee arthroplasty predominantly experienced lateral condylar lift-off whereas subjects with posterior-stabilized total knee arthroplasties experienced either medial or lateral condylar lift-off. Subjects having a posterior-stabilized total knee arthroplasty experienced significantly greater weightbearing range of motion.     

Kinematic analysis of kneeling in cruciate‐retaining and posterior‐stabilized total knee arthroplasties

Kneeling is an important function of the knee for many activities of daily living. In this study, we evaluated the in vivo kinematics of kneeling after total knee arthroplasty (TKA) using radiographic based image‐matching techniques. Kneeling from 90 to 120° of knee flexion produced a posterior femoral rollback after both cruciate‐retaining and posterior‐stabilized TKA. It could be assumed that the posterior cruciate ligament and the post‐cam mechanism were functioning. The posterior‐stabilized TKA design had contact regions located far posterior on the tibial insert in comparison to the cruciate‐retaining TKA. Specifically, the lateral femoral condyle in posterior‐stabilized TKA translated to the posterior edge of the tibial surface, although there was no finding of subluxation. After posterior‐stabilized TKA, the contact position of the post‐cam translated to the posterior medial corner of the post with external rotation of the femoral component. Because edge loading can induce accelerated polyethylene wear, the configuration of the post‐cam mechanism should be designed to provide a larger contact area when the femoral component rotates. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:435–442, 2008     

Observations of femoral rollback in cruciate-retaining knee arthroplasty

The current study evaluated kinematics of the knee during a stair-climbing activity after total knee arthroplasty. All patients received a posterior cruciate ligament retaining prosthesis of the same design, having an anatomically shaped femoral component and an unconstrained tibial insert. All patients had the same surgical technique done by two experienced surgeons. Patients had some posterior femoral rollback and screw-home type axial rotations during weightbearing activities. However, patients treated by different surgeons had different patterns of tibiofemoral motions. In Group 1, rollback occurred early in the flexion range and was maintained until 80 degrees flexion. In Group 2, the lateral condyle had rollback in early flexion, but both condyles translated forward as flexion increased to 80 degrees. An anatomic femoral component seems to be necessary to produce consistent early femoral rollback. However, soft tissue balance can have a significant effect on the kinematics of sagittally unconstrained posterior cruciate retaining total knee arthroplasty, because it may vary among surgeons.     

In vivo determination of total knee arthroplasty kinematics: a multicenter analysis of an asymmetrical posterior cruciate retaining total knee arthroplasty

The objective of this study was to determine if consistent posterior femoral rollback of an asymmetrical posterior cruciate retaining (PCR) total knee arthroplasty was mostly influenced by the implant design, surgical technique, or presence of a well-functioning posterior cruciate ligament (PCL). Three-dimensional femorotibial kinematics was determined for 80 subjects implanted by 3 surgeons, and each subject was evaluated under fluoroscopic surveillance during a deep knee bend. All subjects in this present study having an intact PCL had a well-functioning PCR knee and experienced normal kinematic patterns, although less in magnitude than the normal knee. In addition, a surprising finding was that, on average, subjects without a PCL still achieved posterior femoral rollback from full extension to maximum knee flexion. The findings in this study revealed that implant design did contribute to the normal kinematics demonstrated by subjects having this asymmetrical PCR total knee arthroplasty.     

In vitro investigation of knee joint kinematics following cruciate retaining versus cruciate sacrificing total knee arthroplasty

The aim of this biomechanical study was to investigate knee joint kinematics following total knee arthroplasty. We compared eight congruent posterior cruciate ligament retaining and four ultracongruent cruciate sacrificing Natural Knee prostheses to the untreated human cadaveric knee joint. A six-degree-of-freedom testing device was used to evaluate knee joint kinematics with a load of 300 Newton and without load application (0 Newton). Statistical analysis was performed using the Wilcoxon rank sum test. A significant increase in antero-posterior translation and tibial rotation was seen in both types of total knee arthroplasty. Implantation of the ultracongruent prosthesis was followed by distinctly more kinematic changes in comparison to the congruent prosthesis. Load application of 300 Newton leads to an anterior dislocation of the femoral component of the ultracongruent prosthesis at 60 degrees of flexion in vitro, indicating an increased demand of compensatory muscular activity in vivo.     

Bi‐Cruciate Retaining Total Knee Arthroplasty Does Not Restore Native Tibiofemoral Articular Contact Kinematics During Gait

Bi‐cruciate retaining (BCR) total knee arthroplasty (TKA) design preserves both anterior and posterior cruciate ligaments with the potential to restore normal posterior femoral rollback and joint kinematics. Abnormal knee kinematics and “paradoxical” anterior femoral translation in conventional TKA designs have been suggested as potential causes of patient dissatisfaction. However, there is a paucity of data on the in vivo kinematics and articular contact behavior of BCR‐TKA. This study aimed to investigate in vivo kinematics, articular contact position, and pivot point location of the BCR‐TKA during gait. In vivo kinematics of 30 patients with unilateral BCR‐TKA during treadmill walking was determined using validated dual fluoroscopic imaging tracking technique. The BCR‐TKA exhibited less extension than the normal healthy knee between heel strike and 48% of gait cycle. Although the average external rotation trend observed for BCR TKA was similar to the normal healthy knee, the range of motion was not fully comparable. The lowest point of the medial condyle showed longer anteroposterior translation excursion than the lateral condyle, leading to a lateral‐pivoting pattern in 60% of BCR TKA patients during stance phase. BCR‐TKA demonstrated no statistical significant differences in anterior–posterior translation as well as varus rotation, when compared to normal healthy knees during the stance phase. However, sagittal plane motion and tibiofemoral articular contact characteristics including pivoting patterns were not fully restored in BCR TKA patients during gait, suggesting that BCR TKA does not restore native tibiofemoral articular contact kinematics. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1929–1937, 2019     

Detrimental kinematics of a flat on flat total condylar knee arthroplasty

Fourteen subjects having a flat on flat condylar posterior cruciate retaining total knee arthroplasty were evaluated under different in vivo weightbearing conditions, with six performing a deep knee bend and eight walking at normal gait. An interactive model fitting algorithm was used to convert two-dimensional fluoroscopic images into three-dimensional computer aided design solid model images. The femorotibial contact positions for the medial and lateral condyle started posterior at full extension. With a deep knee bend the lateral condyle acted as a pivot, and the medial condyle slid in the anterior direction. Five of six had lateral condyle liftoff (maximum 1.6 mm) and abnormal positive screw home motion was seen from 0 degree to 90 degrees flexion. During gait, all femorotibial contact positions were posterior in extension and throughout the cycle. Six of eight patients experienced lateral condyle liftoff (maximum 3.5 mm), but minimal screw home motion was seen. Abnormal medial condyle posteroanterior sliding, lateral condyle liftoff, and erratic screw home motion may be related to abnormal wear characteristics of this flat on flat condylar design.     

In vivo comparison of knee kinematics for subjects having either a posterior stabilized or cruciate retaining high-flexion total knee arthroplasty

The objective of this study was to determine the in vivo kinematics for subjects having either a fixed posterior stabilized (PS) or cruciate retaining (CR) high-flexion total knee arthroplasty (TKA). Three-dimensional kinematics from full extension to maximum flexion were determined for 30 subjects (15 PS, 15 CR) using fluoroscopy. On average, the PS subjects demonstrated 112 degrees of weight-bearing (WB) flexion, -6.4 mm of posterior femoral rollback, and 2.9 degrees of axial rotation. The CR subjects averaged 117 degrees of WB flexion, -4.9 mm of posterior femoral rollback, and 4.8 degrees of axial rotation. Posterior femoral rollback of the lateral condyle occurred for all PS TKAs and in 93% of the CR TKAs. Only 2 subjects in each group experienced greater than 1.0 mm of condylar lift-off. Subjects in both TKA groups demonstrated excellent WB ranges of motion and kinematic patterns similar to the normal knee, but less in magnitude.     

Functional comparison of posterior cruciate retention and substitution knee replacement

Thirty-eight matched pairs of osteoarthritic knees from patients who underwent primary total knee replacements with minimum 2 years of followup were studied to compare the functional outcome between a cruciate retention and posterior stabilized design with essentially identical articulation surfaces. Patients were matched for age, weight, gender, diagnosis, activity, deformity of the knee, type of tibial component, and duration of followup. The patients were evaluated functionally by three methods: the Knee Society scoring system; a self-administered questionnaire; and an activity rating based on distance walked. In addition, in vivo fluoroscopic examination was performed in 10 cruciate retention and 10 posterior stabilized knees to determine the functional knee kinematics. Results showed that by patient self-assessment, functional improvement was achieved in 35 (92%) cruciate retention knees and 36 (95%) posterior stabilized knees. There was no statistically significant difference between the two groups in the clinical evaluations. Fluoroscopic kinematics showed that the posterior stabilized knee experienced anteroposterior femorotibial translation more similar to the normal knee during normal gait and deep knee bend. These clinically equivalent results are not in agreement with the predicted better functional results of cruciate retained knees as determined by gait studies.     

Partial and Combined Partial Knee Arthroplasty: Greater Anterior-Posterior Stability Than Posterior Cruciate–Retaining Total Knee Arthroplasty

BackgroundLittle is known regarding anterior-posterior stability after anterior cruciate ligament–preserving partial (PKA) and combined partial knee arthroplasty (CPKA) compared to standard posterior cruciate–retaining total knee arthroplasty (TKA).MethodsThe anterior-posterior tibial translation of twenty-four cadaveric knees was measured, with optical tracking, while under 90N drawer with the knee flexed 0-90°. Knees were tested before and after PKA, CPKA (medial and lateral bicompartmental and bi-unicondylar), and then posterior cruciate–retaining TKA. The anterior-posterior tibial translations of the arthroplasty states, at each flexion angle, were compared to the native knee and each other with repeated measures analyses of variance and post-hoc t-tests.ResultsUnicompartmental and bicompartmental arthroplasty states had similar laxities to the native knee and to each other, with ≤1-mm differences throughout the flexion range (P ≥ .199). Bi-unicondylar arthroplasty resulted in 6- to 8-mm increase of anterior tibial translation at high flexion angles compared to the native knee (P ≤ .023 at 80-90°). Meanwhile, TKA exhibited increased laxity across all flexion angles, with increased anterior tibial translation of up to 18 ± 6 mm (P < .001) and increased posterior translation of up to 4 ± 2 mm (P < .001).ConclusionsIn a cadaveric study, anterior-posterior tibial translation did not differ from native laxity after PKA and CPKA. Posterior cruciate ligament–preserving TKA demonstrated increased laxity, particularly in anterior tibial translation.     

Kneeling kinematics after total knee arthroplasty: anterior-posterior contact position of a standard and a high-flex tibial insert design

Deep flexion activities including kneeling are desired by patients after total knee arthroplasty. This in vivo radiographic study sought to reveal the effect of tibial insert design on tibiofemoral kinematics during kneeling. One group of patients received standard posterior stabilized tibial inserts, whereas the other group received posterior stabilized tibial inserts (Flex inserts) that were designed to allow more flexion. The patients with the Flex inserts achieved greater range of motion without different tibiofemoral contact behavior.     

Comparison of kinematic analysis by mapping tibiofemoral contact with movement of the femoral condylar centres in healthy and anterior cruciate ligament injured knees.

Two methods of analysis of knee kinematics from magnetic resonance images (MRI) in vivo have been developed independently: mapping the tibiofemoral contact, and tracking the femoral condylar centre. These two methods are compared for the assessment of kinematics in the healthy and the anterior cruciate ligament injured knee. Sagittal images of both knees of 20 subjects with unilateral anterior cruciate ligament injury were analysed. The subjects had performed a supine leg press against a 150 N load. Images were generated at 15 degrees intervals from 0 degrees to 90 degrees knee flexion. The tibiofemoral contact, and the centre of the femoral condyle (defined by the flexion facet centre (FFC)), were measured from the posterior tibial cortex. The pattern of contact in the healthy knee showed the femoral roll back from 0 degrees to 30 degrees, then from 30 degrees to 90 degrees the medial condyle rolled back little, while the lateral condyle continued to roll back on the tibial plateau. The contact pattern was more posterior in the injured knee (p=0.012), particularly in the lateral compartment. The medial FFC moved back very little during knee flexion, while the lateral FFC moved back throughout the flexion arc. The FFC was not significantly different in the injured knee (p=0.17). The contact and movement of the FFC both demonstrated kinematic events at the knee, such as longitudinal rotation. Both methods are relevant to design of total knee arthroplasty: movement of the FFC for consideration of axis alignment, and contact pattern for issues of interface wear and arthritic change in ligament injury.     

Effects of Posterior Tibial Slope on a Posterior Cruciate Retaining Total Knee Arthroplasty Kinematics and Kinetics

BackgroundIt has been hypothesized that increasing posterior tibial slope can influence condylar rollback and play a role in increasing knee flexion. However, the effects of tibial slope on knee kinematics are not well studied. The objective of this study is to assess the effects of tibial slope on femorotibial kinematics and kinetics for a posterior cruciate retaining total knee arthroplasty design.MethodsA validated forward solution model of the knee was implemented to predict the femorotibial biomechanics of a posterior cruciate retaining total knee arthroplasty with varied posterior slopes of 0°-8° at 2° intervals. All analyses were conducted on a weight-bearing deep knee bend activity.ResultsIncreasing the tibial slope shifted the femoral component posteriorly at full extension but decreased the overall femoral rollback throughout flexion. With no tibial slope, the lateral condyle contacted the polyethylene 6 mm posterior of the midline, but as the slope increased to 8°, the femur shifted an extra 5 mm, to 11 mm posterior of the tibial midline. Similar shifts were observed for the medial condyle, ranging from 7 mm posterior to 13 mm posterior, respectively. Increasing posterior slope decreased the posterior cruciate ligament tension and femorotibial contact force.ConclusionThe results of this study revealed that, although increasing the tibial slope shifted the femur posteriorly at full extension and maximum flexion, it reduced the amount of femoral rollback. Despite the lack of rollback, a more posterior location of condyles suggests lower chances of bearing impingement of the posterior femur and may explain why increasing slope may lead to higher knee flexion.     

Anterior cruciate-retaining total knee arthroplasty

Fifty patients underwent bilateral total knee arthroplasty retaining both cruciate ligaments on one side and only the posterior cruciate ligament on the other. Patients were questioned about pain, instability, “feel,” and ability to climb stairs. Seventy percent of patients stated that their anterior and posterior cruciate-retaining knee was their better knee overall. Ten percent stated that their posterior cruciate-only knee was better. Twenty percent could find no difference. There were no meaningful differences in inpatient care, physical therapy requirements, strength, range of motion, or component positioning. Fourteen patients handled stairs using each knee equally. Twenty-nine climbed stairs leading with the anterior and posterior cruciate-retaining knee and seven patients led with the posterior cruciate-only knee. Complaints of clunks, pops, and clicks occurred in 11 patients with posterior cruciate-only knee arthroplasties and in 4 patients retaining both anterior and posterior cruciate ligaments. Retaining the anterior cruciate ligament can provide a knee that subjectively “feels” better.     

Functional medical ligament balancing in total knee arthroplasty

Function of the anterior and posterior oblique portions of the medial collateral ligament and the posterior capsule in flexion and extension was evaluated in eight knee specimens after posterior cruciate retaining total knee arthroplasty. The posterior oblique portion of the medial collateral ligament was released subperiosteally in four specimens, and the anterior portion was released in four specimens. The medial posterior capsule was released in each group, then the remaining portion of the medial collateral ligament was released. Release of the posterior oblique portion produced moderate laxity at full extension and at 30 degrees flexion, and posterior capsule release produced additional laxity in full extension. Release of the anterior portion produced major laxity at 60 degrees and 90 degrees flexion. Complete medial collateral ligament release increased laxity significantly in both groups in flexion and extension. This rationale was tested in a clinical study of 82 knees (76 patients) in which 62 (76%) required medial collateral ligament release to correct varus deformity during posterior cruciate retaining total knee arthroplasty. Twenty-two knees (35.5%) were tight medially in extension only, and were corrected by releasing the posterior oblique portion. Thirty-one knees (50%) were tight medially in flexion only, and were corrected by releasing the anterior portion. Nine knees (14.5%) were tight medially in flexion and extension and required complete medial collateral ligament release, but three knees (4.8%) remained tight in extension and required medial posterior capsule release to correct flexion contracture and medial ligament contracture. Seventeen (27%) had partial posterior cruciate ligament release to correct excessive rollback of the femoral component on the tibial surface.     

Polyethylene damage and knee kinematics after total knee arthroplasty.

This study characterizes the relationship between in vivo knee kinematics and polyethylene damage by combining fluoroscopic analysis of tibiofemoral contact during dynamic activities and implant retrieval analysis in the same patients. Six patients (eight knees) underwent posterior cruciate ligament-retaining total knee arthroplasty. All patients participated in fluoroscopic analysis during a stair-rise and descent activity and treadmill gait an average of 18 months after arthroplasty, and articular contact was measured. Subsequently, all polyethylene tibial inserts were retrieved after an average of 26 months in vivo function: three at autopsy and five at revision. There was a statistically significant correlation between the damage location on the retrieved inserts and the articular contact location measured fluoroscopically during the activities. The femoral contact and polyethylene damage occurred predominantly on the posterior half of the tibial articular surface, and the damage pattern was largest in the compartment with the greatest range of in vivo femoral contact for each patient. This study showed that in vivo fluoroscopic analysis can predict the damage location on the polyethylene articular surface.     

Posterior cruciate ligament removal contributes to abnormal knee motion during posterior stabilized total knee arthroplasty

Abnormal anterior translation of the femur on the tibia has been observed in mid flexion (20–60°) following posterior stabilized total knee arthroplasty. The underlying biomechanical causes of this abnormal motion remain unknown. The purpose of this study was to isolate the effects of posterior cruciate ligament removal on knee motion after total knee arthroplasty. We posed two questions: Does removing the posterior cruciate ligament introduce abnormal anterior femoral translation? Does implanting a posterior stabilized prosthesis change the kinematics from the cruciate deficient case? Using a navigation system, we measured passive knee kinematics of ten male osteoarthritic patients during surgery after initial exposure, after removing the anterior cruciate ligament, after removing the posterior cruciate ligament, and after implanting the prosthesis. Passively flexing and extending the knee, we calculated anterior femoral translation and the flexion angle at which femoral rollback began. Removing the posterior cruciate ligament doubled anterior translation (from 5.1 ± 4.3 mm to 10.4 ± 5.1 mm) and increased the flexion angle at which femoral rollback began (from 31.2 ± 9.6° to 49.3 ± 7.3°). Implanting the prosthesis increased the amount of anterior translation (to 16.1 ± 4.4 mm), and did not change the flexion angle at which femoral rollback began. Abnormal anterior translation was observed in low and mid flexion (0–60°) after removing the posterior cruciate ligament, and normal motion was not restored by the posterior stabilized prosthesis. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:1494–1499, 2008     

Proprioception, kinesthesia, and balance after total knee arthroplasty with cruciate-retaining and posterior stabilized prostheses

BACKGROUND: The effect of total knee arthroplasty on proprioception, kinesthesia, and postural control remains controversial. It is argued that retaining the posterior cruciate ligament may help to preserve these sensorimotor functions and improve the longevity of the prosthesis and the functional outcome. We performed a prospective, randomized study to assess proprioception, kinesthesia, and balance following total knee arthroplasty with cruciate-retaining and posterior stabilized prostheses. METHODS: Twenty patients scheduled to undergo total knee arthroplasty were randomly assigned to receive either a cruciate-retaining or a posterior stabilized prosthesis. Joint-position sense, the threshold to detect joint motion, and the subject's ability to balance on an unstable platform were assessed prior to and at least six months after the operation. Paired two-tailed t tests (with a level of significance of p < 0.05) were used to assess the effect of the arthroplasty on the preoperative measures for all subjects. Analysis of covariance was performed to identify the effects of prosthetic design. RESULTS: Following total knee arthroplasty, patients detected motion significantly faster and reproduced joint position with less error. The balance index also improved significantly from the preoperative to the postoperative evaluation. The group treated with the posterior stabilized prosthesis more accurately reproduced joint position when the knee was extended from a flexed position. CONCLUSIONS: Total knee arthroplasty results in mild improvements in proprioception, kinesthesia, and balance. These changes may result from the retensioned capsuloligamentous structures and reduced pain and inflammation. Retention of the posterior cruciate ligament does not appear to significantly improve proprioception and balance compared with those functions in patients with a posterior stabilized total knee design.     

Effect of tibial slope or posterior cruciate ligament release on knee kinematics

An experimental study using fresh human cadaver knees was designed to evaluate the effect of partial posterior cruciate ligament release or posterior tibial slope on knee kinematics after total knee arthroplasty. Varus and valgus laxity, rotational laxity, anteroposterior laxity, femoral rollback, and maximum flexion angle were evaluated in a normal knee, an ideal total knee arthroplasty, and a total knee arthroplasty in which the ligaments were made to be too tight in flexion. The total knee arthroplasty specimens then were subjected to either partial posterior cruciate ligament release or increased posterior tibial slope, and the tests were repeated. Posterior tibial slope increased varus and valgus laxity, anteroposterior laxity, and rotational laxity in the knee that had flexion tightness. Posterior cruciate ligament release corrected only anteroposterior tightness, and had no effect on the abnormal collateral ligament tightness. Increased posterior tibial slope significantly improved varus and valgus laxity and rotational laxity in the knee that was tight in flexion more than with release of the posterior cruciate ligament. Therefore increasing posterior tibial slope is preferable for a knee that is tight in flexion during total knee arthroplasty.