2019 Colorado Alphaherpesvirus Latency Society symposium

Journal of NeuroVirology - Meeting Report on the 9th Annual Symposium of the Colorado Alphaherpesvirus Latency Society (CALS) held on May 8–11, 2019, in Vail, CO.     

2018 Colorado Alphaherpesvirus Latency Society Symposium

Meeting Report on the 8th Annual Symposium of the Colorado Alphaherpesvirus Latency Society (CALS), held on May 16–19, 2018, in Vail, Colorado.     

Programme

Conjoint Meeting of the VI International Symposium of the Autonomic Nervous System & XXII International Congress of Neurovegetative ResearchRitz-Carlton Hotel, Phoenix, Arizona, USA 17–19 November 1995

Programme     

Paroxysmal dysarthria and ataxia in a patient with Behçet's disease

The paroxysmal attacks which are frequently encountered in the course of multiple sclerosis (MS) are characterised by their sudden onset, short duration and frequent repetition. Such attacks have also been reported in some other diseases affecting the CNS, such as systemic lupus erythematosus. However, to our knowledge, they have not been reported in neuro-Behçet's disease (NBD). A patient with NBD who developed paroxysmal dysarthriaataxia attacks is presented, and the similarity of some clinical, laboratory, and neuroradiological aspects of NBD and MS are discussed with special emphasis on magnetic resonance imaging findings.This work was presented as a poster at the Multiple Sclerosis Symposium (Istanbul, 8–11 May 1994)     

Proceedings of the Society of British Neurological Surgeons

The 83rd Meeting of the Society of British Neurological Surgeons was held in Liverpool on 11-13 May 1972.     

Pattern of interleukin-6 receptor complex immunoreactivity between cortical regions of rapid autopsy normal and Alzheimer’s disease brain

Involvement of the interleukin–6 receptor complex (IL–6RC) in neuroregulatory and immunological processes of the brain and particularly in Alzheimer’s disease (AD) has been hypothesized. The functionally active IL–6RC consists of the cytokine IL–6, which acts through the ligand binding IL–6R and the signal transducing gp130. Using a new immunocytochemical protocol on rapid autopsy cryostat brain sections we studied the expression of the IL–6RC in Braak IV–V staged AD patients compared to normal age–matched controls (HC) across five different cortical regions. Inter–rater reliability of the method was high. The “baseline” expression in normal human brain was determined for IL–6,IL–6R and gp130 in all cortical regions. In normal tissue IL–6 expression was lower in parietal cortex. Higher IL–6R expression was shown in frontal, occipital and parietal cortex, lower expression in temporal cortex and cerebellum. In AD IL–6 expression levels were generally increased in parietal cortex and decreased in occipital cortex compared to controls. IL–6R expression levels were strongly increased in AD frontal and occipital cortex and decreased in temporal cortex and cerebellum. Our findings indicate an altered cortical immunoreactivity pattern of the functional IL–6RC in AD supporting the hypothesis of a disease–related role of IL–6 in AD pathophysiology.Preliminary parts of this work were presented in abstract form at the 28^th Annual Meeting of the Society of Neuroscience, Los Angeles, CA, 1998, at the 29^th Annual Meeting of the Society of Neuroscience, Miami, FL, 1999, at the Neuroinflammation Conference, Washington, DC, 2000 and at the 30^th Annual Meeting of the Society of Neuroscience, New Orleans, LA, 2000.     

Clinical application of the Mullen and Foster method for individualizing phenytoin dosage

The Mullen and Foster method was prospectively applied for individualizing phenytoin dosage in 24 epileptic patients. Accuracy and reliability of the method were assessed by comparing predicted and measured values of plasma phenytoin steady-state concentration. The absolute difference between predicted and measured phenytoin levels was less than 15 percent in 22 of 35 cases (63 percent), between 15 and 25 percent in 8 of 35 cases (23 percent) and more than 25 percent in 6 of 35 cases (17 percent).Presented at the 11th European Symposium on Clinical Pharmacy, Brussels, 20–22 October 1982.     

Coxsackie B antigen in the central nervous system of a patient with fatal acute encephalitis: immunohistochemical studies of formalin-fixed paraffin-embedded tissue

Summary A case of fatal acute encephalitis due to Coxsackie B₁ virus is described. Confirmation of Coxsackie B virus as the etiological agent of encephalitis was based on identification of the virus antigen in formalin-fixed paraffin-embedded tissue sections. In the past, the diagnosis was obtained by serological studies of peripheral blood and viral isolation. This is the first report in which indirect immunofluorescent and immunoper-oxidase methods using rabbit antiserum raised against Coxsackie B types 1–6 was utilized in determining the etiology of encephalitis. It must be emphasized that these methods can be used both on biopsy or autopsy specimens, even retrospectively.Presented in part at the sixty-third Annual Meeting of the American Association of Neuropathologists, Seattle, Washington, June 11–14, 1987     

Psychiatric disorders among elderly Koreans in the United States

This study examines the lifetime prevalence of various psychiatric disorders among 100 Korean elderly in Los Angeles. The instrument used in this study is the Diagnostic Interview Schedule, Version III (DIS III, 1–10). The main finding is of relatively low prevalence of most DSM-III disorders with the exception of alcohol abuse and dependence. The rate of alcoholism is astonishingly high among elderly Korean males in Los Angeles. The findings are compared with the U.S. Epidemiological Catchment Area studies, and with other much larger community studies conducted in Korea. A comparison shows that there are no significant differences in the prevalence of mental disorders between elderly Koreans in Los Angeles and elderly Americans in St. Louis (N=576) except for the prevalence of alcohol abuse and dependence. The lifetime prevalence of DSM-III disorders among Koreans in Korea (N=5100) is generally higher than among elderly Koreans in Los Angeles.Presented at the 144th Annual Meeting of the American Psychiatric Association, New Orleans, May 11–16, 1991.This study was supported in part by the National Research Center on Asian American Mental Health (NIMH RO1 MH44331).     

A survey of some active sheep pineal fractions and a discussion on the possible significance of pteridines in those fractions inin vitro andin vivo assays

Summary Aqueous extracts of sheep pineals are separated on Sephadex G-25. The low molecular weight Sephadex G-25 fractions with antigonadotropic activity are ultrafiltered through the membrane UM 2. The UM 2 filtrate is subsequently filtered through the membrane UM 05. The actions of the different fractions on the anterior hypophysis and hypothalamus are discussed.The fractions which show an activity are further separated on Sephadex G-10. The active Sephadex G-10 fractions of the UM 05 filtrate acting on the anterior hypophysisin vitro are purified by electrophoresis and paper chromatography. After elution of different fluorescence bands the main inhibitory activity is found in a region, with the same Rf value as synthetic 6-biopterin. Gas liquid chromatography and mass spectrometry studies of the isolated fractions are carried out. The mass spectrum of an isolated compound from that fraction is identical with that of synthetic 6-biopterin. Thinlayer chromatography and the results of the Crithidia fasciculata test reveal that the isolated compound is probably identical with 6-L-erythrobiopterin. The activity of the active paper chromatography fraction (C₄) is compared with the activity of three synthetic biopterin-preparationsin vitro andin vivo.The metabolic activities of biopterin derivatives and other pteridines are discussed.A part of this work is presented at the International Symposium on the Pineal Gland, 14–17 November 1977, at Jerusalem, Israel.     

16th International Symposium on the Autonomic Nervous System Westin Resort & Spa, Los Cabos Los Cabos, Mexico October 6–9, 2005

CONTENTS

16^th International Symposium on the Autonomic Nervous SystemWestin Resort & Spa, Los Cabos Los Cabos, Mexico October 6–9, 2005     

CXCL11 is involved in leucocyte recruitment to the central nervous system in neuroborreliosis

We investigated the role of the CXCR3 chemokine CXCL11 (I–TAC) for leukocyte recruitment to the CSF in neuroborreliosis (NB). CXCL11 levels in the CSF of 17 patients with acute NB were elevated compared with 20 non–inflammatory controls (100.1 vs. 54.1pg/ml, p = 0.002). Using a modified Boyden chamber chemotaxis–assay, the CSF of patients with acute NB was more chemotactic than the control CSF–samples (p = 0.001). A strong correlation (p < 0.001) between CXCL11 levels, chemotactic activity and CSF–white cell count was detected. Though the chemotactic activity of CSF from NB patients was only partially reduced by a human recombinant CXCL11 antibody, these findings suggest that, among other chemotactic factors, CXCL11 may play a role in the chemotaxis of mononuclear cells in NB.Presented on the 14^th Meeting of the European Neurological Society (Barcelona, Spain, 26–30 June, 2004). Informed consent for lumbar puncture was obtained from all patients. There was no special financial support. The authors have no conflict of interest     

New Strategies in Neuroprotection and Neurorepair

There are currently few clinical strategies in place, which provide effective neuroprotection and repair, despite an intense international effort over the past decades. One possible explanation for this is that a deeper understanding is required of how endogenous mechanisms act to confer neuroprotection. This mini-review reports the proceedings of a recent workshop "Neuroprotection and Neurorepair: New Strategies" (Iguazu Falls, Misiones, Argentina, April 11-13, 2011, Satellite Symposium of the V Neurotoxicity Society Meeting, 2011) in which four areas of active research were identified to have the potential to generate new insights into this field. Topics discussed were (i) metallothionein and other multipotent neuroprotective molecules; (ii) oxidative stress and their signal mediated pathways in neuroregeneration; (iii) neurotoxins in glial cells, and (iv) drugs of abuse with neuroprotective effects.     

Abstracts of the 19th Annual Meeting of the Japanese Psychogeriatric Society

Venue: Matsumoto Culture Hall Date: 25–26 June 2004
President: Professor Naoji Amano (Shinsyu University Medical School, Department of Psychiatry)
The 19th Annual Meeting of the Japanese Psychogeriatric Society was held in Matsumoto, Nagano Prefecture. The program included two symposiums and two luncheon seminars, and 116 presentations. Psychiatric symptoms and MCI (mild cognitive impairment) are prevalent and these were important topics in the meeting. Symposium I, entitled 'Delusion in the elderly', and Symposium II, entitled 'On MCI', were very productive and generated a lot of discussion.
The next meeting will be held on 15–17 June 2005 in Tokyo Forum and will be presided by Professor Heii Arai, Juntendo Medical College.     

Sex between psychiatric inpatients

This report reviews the literature on the subject of sexual activity between psychiatric inpatients. The author discusses the psychological reasons why patients engage in sexual activity as well as the possible psychological effects. In addition, the author discusses medical considerations including concerns about injury, pregnancy, and venereal disease and legal implications including issues related to wrongful life, wrongful birth and deteriorating mental condition resulting from sexual activity. The report also discusses ethical issues, staff attitudes and various options for management of sexual activity between patients.This paper was presented at the 1985 Annual Meeting of the American Psychiatric Association in Dallas, Texas, May 18–25.     

A case for range and versatility within agencies in planning mental health services

Agencies that provide mental health services have a continuing responsibility for program review and re-examination of policies, procedures, and methods that limit their helping capabilities. Intra-agency planning and administration offer a fruitful area for both improving and increasing treatment and intervention for distressed individuals and families. Range in services and treatment methods and versatility in staff skills are proposed as important aspects of the organization and administration of services. Four aspects of internal organization are examined as possible critical points where improvement could be effected.This article was originally prepared as a resource paper for the Annual Meeting of the American Psychiatric Association, May 4–8, 1964, at Los Angeles, Californ     

Abstracts of the 21st Annual Meeting of the Japanese Psychogeriatric Society

Venue: Toshi Center Hotel (Tokyo)
Date: 30 June–1 July 2006
President: Professor Hiroo Kasahara (Department of Psychiatry, Jikei University School of Medicine, Kashiwa Hospital)
Thema: Achievements in psychogeriatrics and its challenges in the near future
The 21st Annual Meeting of the Japanese Psychogeriatric Society was held in Tokyo. The program included two special lectures, three symposiums, four educational lectures, 87 oral presentations, and 44 poster presentations.
In the special Lecture I entitled 'Mild cognitive impairment: update 2006', Professor Ronald C. Petersen presented the recent understanding of MCI not only for midstream of Alzheimer disease, but also for midstream of frontotemporal dementia or Lewy body disease. In the special Lecture II entitled 'Adaptation depression and late life: an integrated view', Professor Joel Sadavoy demonstrated the importance of depression in late life. Symposium I: 'Review of 100 years of studies on Alzheimer disease and further challenges" was chaired by Professor Masaaki Matsushita and Professor Masatoshi Takeda; Symposium II: "Field study of MCI in our country" was chaired by Professor Akira Hommma and Professor Yoshio Morita; Symposium III: "Biological treatment and non-biological intervention for dementia" was chaired by Professor Haruo Kashima and Professor Ryo Fukatsu. All three symposiums were fruitful with exciting discussions by the active audience.
The next annual meeting will be held 14–18 October 2007 in Osaka, under Professor Yoshio Morita (Department of Psychiatry, Hyogo Medical School) and will be co-organized with the 13th Congress of International Psychogeriatric Association chaired by Professor Masatoshi Takeda (Department of Psychiatry, Osaka University Graduate School of Medicine) and the 26th Meeting of Japanese Society for Dementia Research chaired by Professor Akira Honma (Department of Dementia Intervention, Tokyo Metropolitan Institute of Gerontology).     

Posttraumatic stress symptoms in London school children following September 11, 2001: an exploratory investigation of peri-traumatic reactions and intrusive imagery

Threatening intrusive images are central to posttraumatic stress disorder. It has been suggested that intrusive imagery in the context of a sense of threat leads to the development and persistence of posttraumatic stress symptoms. This study investigates London school children's (N=76; age 10–11 years) self-reported posttraumatic stress symptoms in response to viewing the attacks of September 11, 2001 on television. Assessments were made at two time points. A minority of participants reported moderate–severe symptoms with functional impairment at 2 months (14.5%) and 6 months (9.2%) after viewing the September 11 events. After controlling for symptom stability, persistent symptoms were associated with peri-traumatic factors, notably perceiving that one's life was in danger. The combined effect of intrusive imagery and peri-traumatic life threat was associated with symptom persistence. Assessments of intrusive image content via checklist and free-report indicated that the images were directly related to September 11 and were fairly stable over time. Implications for treating children's intrusive images following stressful events are explored.     

Periventricular pathology in hydrocephalic rabbits before and after shunting

Summary Hydrocephalus was induced in adult rabbits by injection of silicone oil into the cisterna magna. The frontal horns of the lateral ventricles enlarged to the greatest degree and reached maximum size within 3 days. Cilia and microvilli were progressively lost from the ependymal surface primarily over the corpus callosum. Stretching and flattening of ependymal cells was most pronounced over the septal area. Mitotic activity was significantly increased among ependymal cells and subependymal astrocytes over the caudate nucleus and corpus callosum during the 2 weeks immediately following induction of hydrocephalus. Cerebrospinal fluid shunting returned the ventricles to normal size. Following shunting, however, the periventricular tissue did not resume a normal appearance. Longer durations of hydrocephalus were associated with less recovery of the periventricular tissue following shunting.Supported by grants from the Health Sciences Centre Research Foundation, the Medical Research Council of Canada, the Manitoba Health Research Council, and the Manitoba Medical Services Foundation. Dr. Del Bigio was supported by a Fellowship from the Medical Research Council of Canada. This work was awarded the Kenneth Shulman Memorial Award by the Pediatric Section of the American Association of Neurological Surgeons.This study was presented in part at the 29th Annual Meeting of the Canadian Federation of Biological Sciences in Guelph, Ontario, Canada, June 16–20, 1986 and at the 16th Annual Meeting of the Pediatric Section of the American Association of Neurological Surgeons Meeting in Chicago, IL, December 8–11, 1987     

The present and future state of pediatric neurosurgery in Latin America

After a previous review of the paper presented during the Pediatric Neurosurgery Symposium held in New York during the XV Meeting of ISPN on the situation of pediatric neurosurgery in Latin America, the present situation will be reviewed with special emphasis on economic factors, the technical gap between Latin American and First World countries, manpower, the impact of private health organization and the inclusion of pediatric neurology courses in university curricula.