Validation and application of a subjective knee questionnaire

Patients' complaints on limitations in activities of daily living (ADL) and sports are possible signs for various injuries of the knee joint. These complaints can be easily assessed by the patient using a questionnaire with visual analogue scale (VAS) responses. A German translation of the English questionnaire concerning knee complaints [4] has been validated and tested for clinical use. It consists of 28 questions. For the statistical analysis, an overall score (VAS score) of the questionnaire was determined. The validation included an expert evaluation on the content of the questionnaire, a test for the reliability, a comparison with subjective knee scoring systems (Cincinnati score, Lysholm score) and a test on VAS score results in patient groups with various knee injuries (discrimination of patients). For the evaluation of operative treatment results, the responsiveness of the questionnaire was tested in patients undergoing arthroscopic meniscus surgery and anterior cruciate ligament reconstruction. The investigation was conducted prior to the operation, 2, 6, 12 and 24 weeks after surgery for both groups and also 36 weeks after surgery for the cruciate ligament patients. Interviews conducted with knee surgeons (so-called knee experts) revealed that 85% judged the questionnaire as being acceptable for clinical use. The reliability of the VAS score for healthy individuals wasr=0.86. The reliability for patients in a postoperative rehabilitation programme wasr=0.92. The correlation coefficient for the Lysholm score wasr=0.88 and for the Cincinnati scorer=0.91. By means of the VAS score we were able to assess the extent of limitations in knee function in various patient groups with meniscus lesions, insufficiency of the anterior and posterior cruciate ligaments and chondromalacia. However, the VAS score was not specific for a single knee disorder. In patients who had undergone partial meniscal resection and anterior cruciate ligament (ACL) reconstruction, alterations in knee function could be adequately evaluated by means of the VAS score. When comparing the VAS score prior to and after the operation, an evaluation of the treatment result was possible. With such a questionnaire using the patient's VAS responses, subjective data can be assessed time-saving for the physician, without observer bias and submitted to statistical analysis. The questionnaire can be used as a simple and valid instrument for measuring the subjective outcome in knee surgery.A poster presentation of this work was presented at the 33th Annual German Sports Medicine Convention in Paderborn, Germany, Oct. 14, 1993     

Measurement of an intact knee kinematics using gait and fluoroscopic analysis

A method has been introduced in this paper to measure the kinematics of a knee joint and to use it as a boundary condition to model the knee’s mechanical behaviour. A mobile C-Arm fluoroscopy system (Ziehm Vision R) and a CCD camera were used for the measurement of a patient’s knee kinematics. The fluoroscopic images were recorded with 12 fps and then sent to Matlab software (Mathworks, Natick, MA, USA) for image processing. In parallel, CT scan images of the knee bones were used to create the 3D anatomical geometry of the knee by aid of Mimics software (Materialise NV). However, the geometrical model of the two medial and lateral menisci was generated from MRI data. The 3D geometrical model of the knee was then sent to Abaqus finite element software (Simulia Dassault Systems) to analyse the knee joint contact loads by introducing the boundary condition which was obtained from fluoroscopic images. The finite element model was used to evaluate the stress distribution on the cartilages during the gait. The result was then compared with the experimental data of gait analysis. The comparison between the results showed a close agreement between the two outcomes.     

Relationship between radiographic measurements and knee adduction moment using 3D gait analysis

BackgroundRadiographic factors estimate the state of the static knee joint, and it is questionable how well these parameters reflect the dynamic knee condition. The external knee adduction moment (KAM) during gait is known to be a kinetic variable contributing to osteoarthritis progression. This study aims to investigate the effects of static radiographic parameters on the dynamic KAM during gait.MethodsOverall, 123 patients (mean age, 65.7 years; standard deviation, 8.1 years; 34 men and 89 women) were included. Seven radiographic parameters including the mechanical tibiofemoral angle (mTFA), Kellgren-Lawrence grade, and ankle joint line orientation (AJLO) were measured on radiographs, and the maximum KAM and KAM-time integral in the stance phase were obtained using three-dimensional gait analysis. The correlation and multiple regression analyses were performed for identifying significant radiographic measurements associated with the KAM.ResultsMost of the radiographic measurements correlated with the maximum KAM and KAM-time integral. As a result of multiple regression analysis, the mTFA (p < 0.001) and AJLO (p = 0.003) were identified as significant factors associated with the KAM-time integral (R² = 0.450); the mTFA (p < 0.001) and AJLO (p = 0.003) were identified as a significant factor associated with the maximum KAM (R² = 0.352) in multiple regression analysis. The discriminant validity of KAM was highest at varus 5.7 degree of the mTFA and 7.5 degree of the AJLO.SignificanceThe mTFA and AJLO were significantly associated with the KAM. However, to be used as a surgical indication for corrective osteotomy, a longitudinal study is needed to validate whether the mTFA and AJLO values directly cause osteoarthritis progression as we have suggested.Level of evidenceIII.     

Analysis of subjective knee complaints using visual analog scales

A questionnaire using a system of visual analog scales was developed for analyzing subjective knee complaints. This system was tested on 117 consecutive patients who had undergone knee surgery and 65 patients at their initial office evaluation of a knee disorder. The validity of and patient affinity for this type of questionnaire was compared with that of three other established subjective evaluation methods. The visual analog scale system was shown to be valid and comparable to other methods while offering several advantages. It brought greater sensitivity and greater statistical power to data collection and analysis by allowing a broader range of responses than did traditional categorical responses. It removed bias that was introduced by examiner questioning, and it allowed graphic temporal comparisons. Most importantly, patient affinity was higher for this type of subjective evaluation than for other methods.     

Multiple ligament knee reconstruction clinical follow-up and gait analysis

Multiple ligament knee injuries are serious and rare injures that have not been studied using advanced gait analysis techniques. The purpose of this study was to perform clinical follow-up and gait analysis on patients with multiple knee ligament reconstruction. Twenty-four patients who underwent a multi-ligament knee reconstruction by a single surgeon volunteered to participate in this study. We performed complete clinical exam including instrumented ACL exam (KT-1000), and radiological exam including weight-bearing and PCL stress radiographs (TELOS) at minimum 2 years post index surgery. In addition, we performed complete three-dimensional gait analysis on 18 patients. We used a 10-camera, high speed (120 Hz) motion analysis system in conjunction with a multi-axis strain-gage force plate which calculated knee joint kinetics and kinematics while subjects performed flat-ground walking and stair-descent tasks. Kinematic and kinetic variables were compared between reconstructed and contralateral knees and unmatched, healthy control knees. All knee joint moments were normalized to subjects’ weight. Clinical: Average knee joint flexion/extension 123.6 ± 15.5/1.7 ± 3.5, respectively. Average KT-1000 side-to-side difference was 1.2 ± 2.0 mm, TELOS side-to-side difference on stress radiographs was 4.0 ± 3.1 mm. Median IKDC score was 67 (range 13–94). Fifty-three percent of patients exhibited radiographic evidence of osteoarthritis (OA) on the operative side; one patient on the contralateral knee. During gait analysis, patients exhibited significantly reduced total knee joint range of motion, and external knee flexion moment in the reconstructed knee compared to the contralateral knee and healthy control knees. The magnitude of these differences was greater while descending a step. Finally, patients who had radiographic evidence of knee joint OA had significantly lower magnitude external knee flexion moment compared to those who did not have OA at the time of follow-up. Greater than 2 years after reconstruction, patients with multi-ligament knee injuries are able to return to daily activities. Gait analysis data suggests that patients may be experiencing higher magnitude changes in sagittal plane kinematics and kinetics during demanding functional tasks (stair decent). Changes in walking gait biomechanics may help explain why this group is experiencing unilateral knee joint degeneration.     

关节镜下滑膜切除术治疗膝滑膜结核的临床分析

目的：探讨关节镜下滑膜切除术治疗膝滑膜结核的疗效。方法：对我院1990年1月至2003年7月的23例膝关节滑膜结核的患者在关节镜下行滑膜切除术并取组织送病理检查。结果：术后经随访16—36个月，患者功能恢复良好，症状消失，优良率达到96．3％。结论：关节镜下滑膜切除术治疗膝关节滑膜结核是一种安全有效的治疗方法。     

Parental subjective assessment of gait limitations: Comparison with objective gait variables

BackgroundSubjective assessment is an important part of clinical examination providing quality insights into impairments of body structure and functions. Research into the associations between parental perceptions of gait in children with cerebral palsy (CP) and objective clinical gait measures is limited.Research questionWhat are the parental perceived gait limitations in children with CP and are these perceptions associated with objective clinical gait analysis?MethodsParent questionnaires were retrospectively analysed for children with CP who attended our gait analysis laboratory over a 24-month period. Perceived walking limitations caused by pain, weakness, lack of endurance, mental ability, safety concerns, and balance were recorded on a 5-point Likert scale. Normalised gait speed, normalised step length and the Gait Deviation Index (GDI) were calculated. Differences between responses were assessed using Chi-squared tests with Dunn’s post hoc test with Bonferroni adjustment. Spearman’s rank correlations were performed to determine the relationship between responses and gait parameters.ResultsData from 251 participants were included, mean age 9 ± 3.4 years, Gross Motor Function Classification System (GMFCS) level I = 158, II = 64 and III = 29. Balance was perceived to limit walking to the greatest extent, followed by weakness, lack of endurance, safety concerns, pain and mental ability. This rank was consistent across GMFCS levels I, II and III. Perceived balance limitations showed the strongest correlations with objective gait variables, GDI (r = −0.31 p = 0.000), normalised step length (r = −0.30 p = 0.0000) and normalised gait speed (r = −0.24 p = 0.0001).SignificanceSubjective gait perceptions provide a valuable indication of gait function but are weakly associated with objective clinical gait analysis. Outcome measures that are sensitive to changes in balance may be more responsive to parental concerns and help to satisfy their goals and expectations.     

Frontal plane knee moment in clinical gait analysis: A systematic review on the effect of kinematic gait changes

IntroductionThe frontal plane knee moment (KAM1 and KAM2) derived from non-invasive three-dimensional gait analysis is a surrogate measure for knee joint load and of great interest in clinical and research settings. Many aspects can influence this measure either unintentionally or purposely in order to reduce the knee joint load to relieve symptoms and pain. All these aspects must be known when conducting a study or interpreting gait data for clinical decision-making.MethodsThis systematic review was registered with PROSPERO (CRD42020187038). Pubmed and Web of Science were searched for peer-reviewed, original research articles in which unshod three-dimensional gait analysis was undertaken and KAM1 and KAM2 were included as an outcome variable. Two reviewers independently screened articles for inclusion, extracted data and performed a methodological quality assessment using Downs and Black checklist.ResultsIn total, 42 studies were included. Based on the independent variable investigated, these studies were divided into three groups: 1) gait modifications, 2) individual characteristics and 3) idiopathic orthopedic deformities. Among others, fast walking speeds (1) were found to increase KAM1; There were no sex-related differences (2) and genu valgum (3) reduces KAM1 and KAM2.ConclusionWhile consistent use of terminology and reporting of KAM is required for meta-analysis, this review indicates that gait modifications (speed, trunk lean, step width), individual characteristics (body weight, age) and idiopathic orthopedic deformities (femoral or tibial torsion, genu valgum/varum) influence KAM magnitudes during walking. These factors should be considered by researchers when designing studies (especially of longitudinal design) or by clinicians when interpreting data for surgical and therapeutic decision-making.     

Reliability and validity of knee angles and moments in patients with osteoarthritis using a treadmill-based gait analysis system

BackgroundAlthough commonly used to study knee osteoarthritis (OA), relatively little is known about the reliability and validity of three-dimensional (3D) gait biomechanics derived from treadmill-based systems.Research questionUsing a treadmill-based gait analysis system, our objectives were to: 1) estimate the test-retest reliability of frontal and sagittal plane knee angles and moments in knee OA patients; 2) examine concurrent validity by estimating the associations between treadmill-based and overground (gold standard) measures; and 3) examine known-groups validity by comparing measures between knee OA patients and matched healthy controls.Methods34 patients and 16 controls completed 3D gait analyses using treadmill-based and overground systems. Treadmill walking speed was matched to self-selected overground speed. Marker set, knee angle and moment calculations were consistent for both systems. Patients completed a second test session using the treadmill-based system <24 h later but within 1 week of the first test session. Variables calculated from knee angle and moment gait waveforms during stance were evaluated using Bland and Altman plots, Intraclass Correlation Coefficients (ICC), Pearson correlations (r) and t-tests.ResultsVisual inspection of the Bland and Altman plots did not reveal any systematic differences between test and retest sessions; however, limits of agreement (LoA) were larger for the sagittal plane than the frontal plane. Mean differences between sessions for knee angles were <0.25 degrees and <0.18 %BW*ht for knee moments. ICCs ranged from 0.57-to-0.93 for test-retest reliability. Pearson correlations between treadmill and overground systems ranged from 0.56-to-0.97. Although highly associated, there were substantial differences in the moments, emphasizing they cannot be used interchangeably. Patients had greater first peak knee adduction moments (KAM) than controls [mean difference (95 %CI): 0.55 (−1.07, −0.04), p = 0.03].SignificanceResults suggest frontal and sagittal plane knee angles and moments in patients with knee OA evaluated using a treadmill-based system are reliable and valid.     

Validation of the Godin-Shephard questionnaire in prepubertal girls

PURPOSE: This study was designed to provide validation of the Godin-Shephard questionnaire for the assessment of habitual activity in prepubertal children. METHODS: Twenty-nine female competitive gymnasts and 32 recreational and nongymnasts, aged 7-11 yr, underwent multiple measures of physical activity over a 15 month period. The Godin-Shephard questionnaire (G-S) was completed once, in the middle of the study period. The Physical Activity Checklist Inventory (PACI) was completed 6 times, at intervals throughout the study, for 2 weekend days and 4 weekdays. Caltrac activity monitors (Hemokinetics, Madison, WI) were worn by each subject in two waves consisting of 2 weekdays and 1 weekend day each. Self-reported activity (h/wk) was recorded by the gymnasts in daily logs and for the nongymnasts through quarterly queries regarding participation in organized activities. A rank order was assigned to each subject for each tool. Spearman rank order correlations assessed the relationship between the G-S versus each measure and combination of measures. Subjects were also divided into gymnast and recreational/nongymnast groups, and alternately into 7-9 yr old and >or= 10 yr old groups, re-ranked and re-analyzed. RESULTS: The average rank of combined PACI, Caltrac and h/wk scores showed only moderate correlation with ranked G-S scores for the overall group and for the 7-9 yr old subset, rho = 0.380 (P = 0.003) and rho = 0.422 (P = 0.043), respectively. The average rank of combined PACI and Caltrac scores also showed only moderate correlation with the ranked G-S scores for the gymnast subset, rho = 0.423 (P = 0.025). No measure or combination of measures correlated significantly with the ranked G-S scores for the >or= 10 yr old subset or the nongymnast subset. CONCLUSION: Based upon comparison with multiple single day measures of activity, the G-S did not provide a good estimate of habitual activity in preadolescent females.     

Validation of an ear-worn sensor for gait monitoring using a force-plate instrumented treadmill

A force-plate instrumented treadmill (Hp Cosmos Gaitway) was used to validate the use of a miniaturised lightweight ear-worn sensor (7.4 g) for gait monitoring. Thirty-four healthy subjects were asked to progress up to their maximum walking speed on the treadmill (starting at 5 km/h, with 0.5 km increments). The sensor houses a 3D accelerometer which measures medio-lateral (ML), vertical (VT) and anterior-posterior (AP) acceleration. Maximum signal ranges and zero crossings were derived from accelerometer signals per axis, having corrected for head motion and signal noise. The maximal force, measured by the instrumented treadmill correlated best with a combination of VT and AP acceleration (R-squared = 0.36, p = 0), and combined VT, ML, and AP acceleration (R-squared=0.36, p = 0). Weight-acceptance peak force and impulse values also correlated well with VT and AP acceleration (Weight acceptance: R-squared = 0.35, p = 0, Impulse: 0.26, p = 0), and combined VT, ML, and AP acceleration (Weight acceptance: R-squared = 0.35, p = 0, Impulse: 0.26, p=0). Zero crossing features on the ML axis provided an accurate prediction of the gait-cycle, with a mean difference of 0.03s (-0.01, 0.05 confidence intervals).     

Knock knee and the gait of six-year-old children

AIM: Knock knee (genu valgum) interferes with the locomotive and supporting function of the lower limb. In static conditions the load-bearing axis of the valgus limb is displaced laterally in relation to the middle of the joint, causing the knee joint, the ankle joint, and the foot as a whole to be weighted in the wrong way. The purpose of this work is to examine the influence of knock knee on gait kinematics. METHODS: The gait of twenty-two 6-year-old children of both sexes in whom knock knee had been medically diagnosed was compared with the gait of 33 children of the same age whose knee joints conformed to the norm in formation and position. Gait was recorded separately for the sagittal and the frontal planes, using a video-computer system. RESULTS: The results of the examination indicated statistically significant differences in the gait of the two groups of children. These differences related mainly to the time features of gait and to data on the angles in the knee and ankle joints. Although the results obtained for other features of gait did not reveal statistical differences, these did indicate that the children with knock knee walked more slowly and with a lower cadence. CONCLUSION: The results indicate that knock knee in 6-year-old children has an adverse impact on the mechanics of the lower limb joints in gait and causes a deterioration in gait quality. Thus knock knee in children should not be treated merely as a superficial defect but should be subject to therapy and, more importantly, taken into account when introducing children to early sports training.     

A gait analysis of simulated knee flexion contracture to elucidate knee-spine syndrome

Knee flexion contracture influences the physiological movements in lower extremities and may cause the kinematic changes of the trunk. Our purpose was to investigate static and dynamic changes in trunk kinematics with simulated knee flexion contracture. Ten healthy females averaged 62 years participated in our study. Unilateral knee flexion contractures of 15° and 30° were simulated with a knee brace. Relaxed standing and level walking were measured at our laboratory using a motion analysis system which consisted of five cameras, a force plate, and thirteen retro-reflective markers. Three-dimensional trunk kinematics and vertical knee forces (% Body Weight) with the contractures were compared with those without the contracture. The 15° contracture did not significantly change trunk kinematics. However, the 30° contracture significantly changed the kinematics in each of the following planes. In the coronal plane, the trunk tilted to the contracture side in standing and walking. In the sagittal plane, posterior inclination of the pelvis in standing significantly increased. In addition, anterior inclination of the trunk and pelvis during walking significantly increased. In the axial plane, trunk rotation to the unaffected side significantly decreased during walking. The vertical knee force in the contracture limb decreased, being accompanied by the increase of the force in the unaffected limb during standing and walking. Results of our study suggest that knee flexion contracture significantly influences three-dimensional trunk kinematics during relaxed standing and level walking, and will lead to spinal imbalance. These facts may explain the onset of the “Knee-Spine Syndrome”.     

Development and validation of the international knee documentation committee subjective knee form

A committee of international knee experts created the International Knee Documentation Committee Subjective Knee Form, which is a knee-specific, rather than a disease-specific, measure of symptoms, function, and sports activity. The purpose of this study was to evaluate the reliability and validity of the new International Knee Documentation Committee Subjective Knee Form. To provide evidence for reliability and validity, we administered the final version of the form, along with the Short Form-36, to 533 patients with a variety of knee problems. Analyses were performed to determine reliability, validity, and differential item function related to age, sex, and diagnosis. Factor analysis revealed a single dominant component, making it reasonable to combine all questions into a single score. Internal consistency and test-retest reliability were 0.92 and 0.95, respectively. Based on test-retest reliability, the value for a true change in the score was 9.0 points. The International Knee Documentation Committee Subjective Knee Form score was related to concurrent measures of physical function (r = 0.47 to 0.66) but not to emotional function (r = 0.16 to 0.26). Analysis of differential item function indicated that the questions functioned similarly for men versus women, young versus old, and for those with different diagnoses. In conclusion, the International Knee Documentation Committee Subjective Knee Form is a reliable and valid knee-specific measure of symptoms, function, and sports activity that is appropriate for patients with a wide variety of knee problems. Use of this instrument will permit comparisons of outcome across groups with different knee problems.     

Neurotomy of the rectus femoris nerve: Short-term effectiveness for spastic stiff knee gait: Clinical assessment and quantitative gait analysis

BackgroundStiff knee gait is a troublesome gait disturbance related to spastic paresis, frequently associated with overactivity of the rectus femoris muscle in the swing phase of gait.ObjectiveThe aim of this study was to assess the short-term effects of rectus femoris neurotomy for the treatment of spastic stiff-knee gait in patients with hemiparesis.Patients and methodsAn Intervention study (before-after trial) with an observational design was carried out in a university hospital. Seven ambulatory patients with hemiparesis of spinal or cerebral origin and spastic stiff-knee gait, which had previously been improved by botulinum toxin injections, were proposed a selective neurotomy of the rectus femoris muscle. A functional evaluation (Functional Ambulation Classification and maximal walking distance), clinical evaluation (spasticity – Ashworth scale and Duncan-Ely test, muscle strength – Medical Research Council scale), and quantitative gait analysis (spatiotemporal parameters, stiff knee gait-related kinematic and kinetic parameters, and dynamic electromyography of rectus femoris) were performed as outcome measures, before and 3 months after rectus femoris neurotomy.ResultsCompared with preoperative values, there was a significant increase in maximal walking distance, gait speed, and stride length at 3 months. All kinematic parameters improved, and the average early swing phase knee extension moment decreased. The duration of the rectus femoris burst decreased post-op.ConclusionThis study is the first to show that rectus femoris neurotomy helps to normalise muscle activity during gait, and results in improvements in kinetic, kinematic, and functional parameters in patients with spastic stiff knee gait.     

Multifactorial estimation of hip and knee joint centres for clinical application of gait analysis

Estimation of joint centres is required in gait analysis for kinematic and kinetic elaboration. In general, the method is based on regression equations and palpation of bone prominences. A kinematic approach can also be used at the hip joint but appears to be more demanding for the patients. The method presented here combines different independent approaches and is aimed at reducing the estimation errors caused by from skin motion artefacts and statistical variance of anthropometric data. It is based on minimising an optimisation function in which data from gait kinematics, anthropometric measurements and statistically derived morphological parameters are properly weighted. The procedure is suitable for clinical applications where the range of motion might be reduced and the patients can not perform complicated exercises. Validation has been made on ten normal subjects and ten patients with spina bifida. The results show that the reproducibility of the estimation and the congruency with the external measurements is improved with respect to both the morphologically based approach and the kinematic method. Copyright 1998 Elsevier Science B.V.     

Gender differences in the knee joint loadings during gait

BackgroundThe differences in anatomical structure between men and women are widely known. Unfortunately, the influence of gender on the biomechanics of a healthy knee joint during gait is still poorly understood.Research questionThe aim of the presented study was to determine loads acting in the knee joint during gait, based on the observation of a large group of healthy young adults, in particular to determine the influence of gender on values of forces and moments and their time characteristics during gait cycle.MethodsTime-spatial gait parameters and ground reaction force were registered for 86 persons (43 females and 43 males) using a motion capture system and force plates. The numerical simulation with the AnyBody system was used to estimate loadings acting in the knee joint. Differences between women and men were tested using the unpaired Student's t-test with a Bonferroni correction.ResultsThe maximum values of loadings acting in the knee joint were: 411.1 %BW (body weight) for resultant force, 390.6 %BW for proximo-distal force, 110.8 %BW for antero-posterior force, 77.0 %BW for medio-lateral force, 2.63 %BWh (body weight times height) for flexion/extension moment, 0.97 %BWh for internal/external rotation moment and 5.7 %BWh for abduction/adduction moment. In general, the normalised forces were greater in the male group, while the normalised external moments acting on the knee were greater in the female group. Local extrema of forces during the stance phase were observed earlier for women.SignificanceKnowledge about gender differences in loadings acting in the knee joint can be of great importance in the case of detecting the early stages of gait abnormalities and treatment planning.     

Clinical gait evaluation of patients with knee osteoarthritis

Knee osteoarthritis (KOA) is the most common osteoarthritis in lower limbs, and gait measurement is important to evaluate walking function of KOA patients before and after treatment. The third generation Intelligent Device for Energy Expenditure and Activity (IDEEA3) is a portable gait analysis system to evaluate gaits. This study is to evaluate the accuracy and reliability of IDEEA3 for gait measurement of KOA patients. Meanwhile, gait differences between KOA patients and healthy subjects are examined. Twelve healthy volunteers were recruited for measurement comparison of gait cycle (GC), cadence, step length, velocity and step counts between a motion analysis system and a high-speed camera (GoPro Hero3). Twenty-three KOA patients were recruited for measurement comparison of former five parameters between GoPro Hero3 and IDEEA3. Paired t-test, Concordance Correlation Coefficient (CCC) and Intraclass Correlation Coefficient (ICC) were used for data analysis. All p-values of paired t-tests for GC, cadence, step length and velocity were greater than 0.05 while all CCC and ICC results were above 0.95. The measurements of GC, cadence, step length, velocity and step counts by motion analysis system are highly consistent with the measurements by GoPro Hero3. The measurements of former parameters by GoPro Hero3 are not statistically different from the measurements by IDEEA3. IDEEA3 can be effectively used for the measurement of GC, cadence, step length, velocity and step counts in KOA patients. The KOA patients walk with longer GC, lower cadence, shorter step length and slower speed compared with healthy subjects in natural speed with flat shoes.