共查询到20条相似文献,搜索用时 15 毫秒
1.
We report a case of primary pulmonary rhabdomyosarcoma in a 52-year-old woman. The diagnosis was established after radical right pneumonectomy, mainly based on immunohistochemistry and electron microscopy findings. This type of tumor is rare in adults. Its primary origin is suggested when a pulmonary meta-stasis of rhabdomyosarcoma from another site or a component of a mixed tumor are ruled out. The best treatment is surgery. The prognosis is poor. 相似文献
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患者男,32岁。因“声嘶2年,加重半年”于2005年11月6日入院。外院行喉镜活检示“恶性肿瘤”。喉镜示左侧披裂可见2cm×2cm大小实性肿物,遮盖左侧梨状窝,表面光滑。CT示喉咽部左后侧壁肿块影,向腔内突出,咽腔左侧变窄(图1)。术中见肿物位于环状软骨板后上方,似有包膜,表面喉黏膜光滑,肿物向下达环状软骨下缘,向对侧已越过中线,向前未达会厌。行全喉切除术加双侧颈部清扫。[第一段] 相似文献
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Kato Y Notake H Kimura J Murakami M Hirata A Sakai H Yanai T 《Journal of comparative pathology》2012,147(2-3):191-194
A 2-year-old male Welsh corgi dog was brought to an animal hospital because of left upper eyelid enlargement with lachrymal gland protrusion. The lachrymal and orbital cavity mass was removed surgically. Microscopically, the orbital mass consisted of a mixture of large rhabdomyoblastic and small round tumour cells. Immunohistochemically, the rhabdomyoblastic cells expressed desmin and myoglobin and the small round cells expressed desmin, myogenin and MyoD1. A diagnosis of embryonal rhabdomyosarcoma (ERS) was made. One month later, multiple masses throughout the body were identified, in particular around the cervical region. One of these lesions was sampled and diagnosed as metastatic ERS. The dog died 84 days after the time of first admission. 相似文献
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Agarwal K Kulshrestha R Pahuja S Chadha R 《Indian journal of pathology & microbiology》2003,46(3):457-459
Botryoid rhabdodmyosarcomas are described predominantly in hollow visceral organs. We present case of an embryonal (botryoid) rhabdomyosarcoma arising in mesentery of a two year old male child. 相似文献
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Botryoid rhabdomyosarcoma of the prostate is a rare tumour in children, mostly below 6 years of age. A case of 5 year old male child presenting with acute retention of urine due to botryoid rhabdomyosarcoma of the prostate is described. 相似文献
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Loducca SV Mantesso A de Oliveira EM de Araújo VC 《International journal of surgical pathology》2003,11(1):57-60
Rhabdomyosarcoma is the most common soft-tissue sarcoma of the head and neck region in children and adolescents. Oral cavity involvement is relatively uncommon, with tongue, soft palate, hard palate, and buccal mucosa being the sites of predilection. This report presents a rare case of intraosseous oral rhabdomyosarcoma arising in the mandibular bone of a 6-year-old child. Clinical, radiologic, and histopathologic features and possible pathogenesis are discussed. 相似文献
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Fine-needle aspiration of the prostate has recently gained popularity as a reliable technique in the evaluation of prostatic nodules for malignancy. The cytologic features of adenocarcinoma have been described, but the features of other more unusual tumors have not been widely publicized. We report a case of embryonal rhabdomyosarcoma of the prostate gland with epithelioid cytologic features. 相似文献
13.
Rhabdomyosarcoma is relatively seen in the pediatric age group with the head and neck region as the commonest site. To the best of our knowledge, few cases of laryngeal involvement in adult have been described in the literature. Biologically, rhabdomyosarcoma is different from squamous cell carcinoma, which is the commonest tumor of the larynx. A previously healthy non-smoker 77-year-old lady presented to the ENT outpatient with a six weeks history of intermittent alteration of voice quality. She had no history of sore throat, or any symptoms suggesting laryngo-pharyngeal reflux. Examination showed asymmetry of the left arytenoid cartilage and aryepiglottic fold. She subsequently had a direct laryngoscopy and biopsy. Histology and immunohistochemistry examination suggested the diagnosis of mesenchymal neoplasm. Following discussion at MDT she subsequently had a total laryngectomy. Histology confirmed a completely excised laryngeal rhabdomyosarcoma. Rhabdomyosarcoma of larynx in adult is a rare disease. Surgical treatment with or without adjuvant radiotherapy is currently the treatment of choice for this disease. 相似文献
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Srinivas U Pillai L Kar R Mahapatra M Gujra S Pati HP 《Indian journal of pathology & microbiology》2007,50(4):917-919
Non-hematopoietic malignancies infiltrating bone marrow have always been a source of erroneous diagnosis. Among these, the small round cell tumors like neuroblastomas and rhabdomyosarcomas mimick the hematopoietic blasts. Several case reports of rhabdomyosarcoma mimicking acute leukemia, clinically and morphologically at presentation have been reported in the literature. To the best of our knowledge such an entity has not been reported in Indian literature. We report here one such case of alveolar rhabdomyosarcoma masquerading as acute leukemia. A thorough clinical examination with high degree of suspicion on bone marrow morphology and judicious use of appropriate immunohistochemistry markers will solve many of these cases. 相似文献
15.
Molecular differential pathology of rhabdomyosarcoma 总被引:17,自引:0,他引:17
H Scrable D Witte H Shimada T Seemayer W W Sheng S Soukup A Koufos P Houghton B Lampkin W Cavenee 《Genes, chromosomes & cancer》1989,1(1):23-35
Tumors of the soft tissues are classified histogenetically according to their phenotypic resemblance to normal adult tissue. Here we describe molecular approaches that make it possible to distinguish between one class of these tumors, rhabdomyosarcoma, and other small-, round-cell tumors. We show that the ascertainment of specific genotypic changes can be used to distinguish further between the embryonal and alveolar subtypes of rhabdomyosarcoma. We tested our model in two ways: first, in a retrospective analysis of diagnostically problematic cases of undifferentiated, small-cell tumors and, second, in a blind study of pediatric tumors. Rhabdomyosarcoma was correctly identified in all cases using this strategy alone. The underlying simplicity of the strategy used to define rhabdomyosarcoma subtypes with molecular markers suggests a model by which tumors can be unequivocally identified, which may apply equally well to other human solid tumors. 相似文献
16.
Reza Kheirandish Baharak Akhtardanesh Shahriar Dabiri Omid Azari 《Comparative clinical pathology》2010,19(4):401-403
A 3-year-old, male, German shepherd dog was presented with a unilateral, progressively enlarging subcutaneous mass around
the left eye. A series of diagnostic tests were performed based on the suspicion of neoplasia. Ultrasonography revealed a
large hyperechoic structure with a soft tissue density behind the affected eye. No fluid or polymorphonuclear cells were detected
on fine needle aspiration, however, lymphocytes and unidentifiable cells that were potentially neoplastic were observed. Exenteration
surgery was done, and several samples were obtained for histopathologic examination. Histopathologically, the tumor mass consisted
of high cellular interlacing bundle of pleomorphic, plump spindle to round cell that blended into muscular layer of vessels
included arteries, veins, capillaries, and thin cleft-like vascular spaces. Tumor cells nuclei were cigar-shaped in well-differentiated
areas and pleomorphic oval to round in poorly differentiated areas. Mitotic figures were frequently observed (38 mitoses per
10 high power fields). Immunohistochemical staining revealed strongly positive staining of cytoplasm of tumoral cells for
vimentin and alpha smooth muscle actin, and negative for desmin, S100, and myogenin. On the basis histopathological and immunohistochemical
finding, diagnosis of periorbital angioleiomyosarcoma was made. Angioleiomyosarcoma has not been reported previously in periorbital
tissue in dogs. 相似文献
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Bodié K Gagne GD Sramek MK Desmond DJ Abel SJ Fagerland JA 《Toxicologic pathology》2011,39(6):980-987
During baseline evaluation prior to a preclinical safety study, a 10-month-old male pure-bred Beagle dog was found to have marked thrombocytopenia (6 × 10(3) platelets [PLT]/μL) associated with a mean platelet volume (MPV) of 17.9 fL. Tests for Rickettsia rickettsii, Ehrlichia canis, and Borrelia burgdorferi were negative. Buccal bleeding time was normal. Over 3 months, PLT were 4 to 141 × 10(3) PLT/μL, and MPV was 11.4 to 25.1 fL; however, PLT were <50 × 10(3) PLT/μL and MPV was >16 fL during most of this period. Antinuclear antibody (ANA) and anti-PLT antibody tests were negative. Genotyping for the presence of a beta 1-tubulin mutation demonstrated the normal wild-type gene. Treatment with prednisone resulted in normal values after only 3 days. Ultrastructure of enlarged PLT was consistent with that of immature PLT, characterized by reduced numbers of peripheral microtubules and the presence of rough endoplasmic reticulum, free ribosomes, Golgi apparatus, and a prominent canalicular system. PLT ultrastructure and glucocorticoid responsiveness supported a diagnosis of immune-mediated thrombocytopenia that was masked by the cyclic nature of PLT decreases and lack of clinical signs. Inclusion of such a dog in a preclinical safety study could result in misinterpretation of clinical pathology findings. 相似文献
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STRAUSS L 《The American journal of pathology》1948,24(4):855-887