麻风病人的红细胞免疫粘附受体活性与循环免疫复合物

红细胞免疫粘附受体的活性(red cellimmune adherence-receptor activity)代表免疫系统的一种因子,它在识别补体C_3b和C_4b,粘附抗原—抗体—补体复合物方面起主要作用。目前麻风病人的细胞免疫缺陷,总补体活力的降低已是公认的事实。这种缺陷是否与红细胞的免疫粘附功能改变有关,很值得研究。选本院健康体险合格者做为对照组,排除心、肺、肝、肾等脏器的疾患,共23名,     

SLE患者血流动力学的变化

ＳＬＥ患者血流动力学的变化劳力民，孙国均，蔡绥，张美芳（浙江医科大学附二院皮肤科，杭州３１０００９）ＳＬＥ是一种病因不明的自身免疫性疾病，心血管病变发生率很高［１］，但对其血流动力学变化研究资料很少，本文通过对２５例ＳＬＥ患者无创性心功能测定，以了解...     

红细胞免疫粘附能力在皮肤血管炎发病机理中的作用

循环免疫复合物(CIC)在某些皮肤血管炎的发病机理中起重要作用.机体对CIC的清除能力是影响CIC致病性的重要因素.现认为红细胞是清除CIC过程中的一个关键环节^[1].我们通过对红细胞免疫粘附(RCIA)能力检测,探讨其在与CIC有关皮肤血管炎发病机理中的作用.     

SLE患者甲状腺功能的改变

为了解SLE患者甲状腺功能的改变，检测了26例SLE患者自身甲状腺抗体(TGab，TPOab)和甲状腺功能（T3、T4、FT3、FT4和TSH）。21名健康体检者和20例普通皮炎患者作为对照组。同时将SLE患者甲状腺功能与免疫球蛋白、C3、抗核抗体（ANA）、dsDNA和血沉水平进行相关性分析。甲状腺增大患者行甲状腺穿刺病理检查。结果：SLE组甲状腺自身抗体TPOab、TGab均增高，T3、FT3和FT4水平均较两对照组降低，TSH和T4变化不明显。SLE组甲状腺抗体、甲状腺功能与dsDNA、ANA、血沉、免疫球蛋白和C3水平无相关性。     

带状疱疹患者79例细胞免疫功能变化与临床分析

目的探讨带状疱疹的临床特征及细胞免疫功能。方法分析79例带状疱疹患者年龄、受累神经、合并症及细胞免疫功能状态。结果不同年龄患者细胞免疫功能不同,不同合并症及不同基础用药者的细胞免疫功能不同。结论带状疱疹患者应进行全面分析,对有细胞免疫功能明显低下者,积极寻找原因。     

女性SLE患者性激素变化的研究

本文测定了28例女性SLE患者血中的6种性激素(FSH、LH、E_2、P、T、PRL)。结果表明:LH、E_2明显升高,T显著下降,E_2/T显著升高,活动期患者较非活动期患者T更低,E_2/T更高。各种性激素与疾病的严重度之间无相关性。作者认为性激素的异常可以做为诊断SLE的实验室指标之一。     

带状疱疹患者细胞免疫功能的测定

带状疱疹是由水痘带状疱疹病毒（ＶＺＶ）感染引起的疱疹性疾病。其发病与机体的免疫状态特别是细胞免疫功能降低有关［１］。为了更准确地了解带状疱疹患者细胞免疫功能的变化,我们对３０例带状疱疹患者外周血Ｔ淋巴细胞亚群、自然杀伤细胞（ＮＫ）、白细胞介素２受...     

Treponema pallidum immune adherence test for serodiagnosis of syphilis. 1: An improved method of the TPIA test.

Clinical investigations using the Treponema pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. In this paper an improved method of the TPIA test is described. The test was simple to perform and was highly specific for antitreponemal antibody. Furthermore, as it was possible to use heated T. pallidum as antigen the antigen suspension could be preserved for long periods. The TPIA test for syphilis was evaluated by examining the sera from 40 healthy subjects and from 166 patients with syphilis.     

Treponema pallidum immune adherence test for serodiagnosis of syphilis. 1: An improved method of the TPIA test.

Clinical investigations using the Treponema pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. In this paper an improved method of the TPIA test is described. The test was simple to perform and was highly specific for antitreponemal antibody. Furthermore, as it was possible to use heated T. pallidum as antigen the antigen suspension could be preserved for long periods. The TPIA test for syphilis was evaluated by examining the sera from 40 healthy subjects and from 166 patients with syphilis.     

Treponema pallidum immune adherence test for serodiagnosis of syphilis. 3: Clinical significance and evaluation of treatment.

Antibody titres were measured in patients with clinical syphilis, and the effect of treatment on the results of the Treponema pallidum immune adherence (TPIA) test is reported. In the Treponema pallidum haemagglutination (TPHA) test little change in antibody titre occurred after treatment while in the fluorescent treponemal antibody-absorbed (FTA-ABS) test only a slight decrease occurred. The decrease in the antibody titre in the TPIA test was similar to that in the glass plate test, but the findings were different. From the results of gel filtration of sera obtained from patients with syphilis at different intervals after treatment it was apparent that the decrease in antibody titre after treatment mainly concerned the IgM antibody; thus, because of the high sensitivity of the TPIA test to IgM antibody the test is useful in evaluating the effect of treatment.     

循环免疫复合物与补体测定对SLR临床意义的比较

本文比较54例SLE患者循环免疫复合物(CIC)和补体的临床意义.肾脏受累组的CH₅₀和C₃在病情活动期较缓解期明显降低,其降低程度与病情活动程度平行;而两期的CIC均值都在正常范围内.无肾脏受累组的PEGP在病情活动期较缓解期有明显升高,升高程度与病情活动程度平行;ACA,CH₅₀和C₃则无明显意义.观察结果还提示PEGP异常升高对无肾脏受累者病情加重可能有预测作用.     

Treponema pallidum immune adherence test for serodiagnosis of syphilis. 3: Clinical significance and evaluation of treatment.

Antibody titres were measured in patients with clinical syphilis, and the effect of treatment on the results of the Treponema pallidum immune adherence (TPIA) test is reported. In the Treponema pallidum haemagglutination (TPHA) test little change in antibody titre occurred after treatment while in the fluorescent treponemal antibody-absorbed (FTA-ABS) test only a slight decrease occurred. The decrease in the antibody titre in the TPIA test was similar to that in the glass plate test, but the findings were different. From the results of gel filtration of sera obtained from patients with syphilis at different intervals after treatment it was apparent that the decrease in antibody titre after treatment mainly concerned the IgM antibody; thus, because of the high sensitivity of the TPIA test to IgM antibody the test is useful in evaluating the effect of treatment.