原发性睾丸或阴茎非霍奇金淋巴瘤5例临床分析

目的:探讨男性生殖系统非霍奇金淋巴瘤的临床诊断与治疗。方法:回顾性分析5例男性生殖系统原发性非霍奇金淋巴瘤的临床资料,其中原发于睾丸4例,原发于阴茎1例,并结合文献进行讨论。结果:5例患者均行手术治疗,病理类型均为非霍奇金淋巴瘤,术后3例行化疗,2例行放疗加化疗(原发于睾丸1例,原发于阴茎1例)。术后平均随访25个月,1例死亡,其余均存活。结论:男性生殖系统非霍奇金淋巴瘤临床症状不典型,多发生于老年,预后较差,确诊主要依靠组织病理学及免疫组化,治疗宜采取手术联合放疗及化疗。     

睾丸恶性淋巴瘤(附12例报告)

自１９８４～１９９６年共收治１２例睾丸恶性淋巴瘤，占同期睾丸恶性肿瘤的５．６％，其中双侧２例（１６．６％）。主要症状为无痛性睾丸肿块，病理类型均为非何杰金淋巴瘤，全部患者均行根治性睾丸切除，术后３例行化疗和放疗，８例单纯化疗。７例２年内死亡（６３．６％）。对睾丸恶性淋巴瘤应采用积极综合治疗，以提高生存率。     

肾脏和睾丸原发性非霍奇金淋巴瘤(附八例报告)

目的探讨泌尿生殖系原发性恶性淋巴瘤的临床特点。方法总结１９８０～１９９７年收治肾脏和睾丸原发性恶性淋巴瘤共８例,其中肾脏２例,睾丸６例,病理类型均为非霍奇金淋巴瘤。结果全部患者均手术治疗,术后１例行化疗和放疗,２例行单纯放疗,５例单纯化疗。２例生存已超过３年和２年。结论对肾脏和睾丸原发性非霍奇金淋巴瘤应积极采取手术治疗,术后辅以化疗、放疗,以提高生存率     

睾丸原发性恶性淋巴瘤1例报告(附文献复习)

睾丸原发性恶性淋巴瘤临床少见 ,我们收治一例报告如下。患者 ,男性 ,4 6岁。主因左侧睾丸无痛性肿物 3个月于 1997年 12月 2日入院。查体 :一般情况良好 ,全身浅表淋巴结未触及肿大 ,左侧睾丸 4 .5ｃｍ× 3.0ｃｍ× 3.0ｃｍ ,质硬 ,表面光滑 ,轻压痛。Ｂ超示 :左睾丸 4 .5ｃｍ× 2 .8ｃｍ大小 ,内部回声不均匀 ,并可见多处不规则低回声区。血流较右侧明显增强。盆腔及腹腔未探及肿大淋巴结。血常规正常 ,ＡＦＰ 2 6.0ｎｇ/ｍｌ(正常值 <50ｎｇ/ｍｌ)ＨＣＧ 83.4ｍＩｕ/ｍｌ(正常值 <12 0ｍＩｕ/ｍｌ)ＣＥＡ 6.0ｎｇ/ｍｌ(正常值 <5.0ｎｇ/…     

睾丸鞘膜移植治疗阴茎Peyronies病(附4例报告)

目的 探讨睾丸鞘膜移植治疗严重的阴茎Peyronies病的临床疗效及术后对性功能的影响.方法 回顾性分析2007年6月至2009年4月4例严重阴茎Peyronies病患者的临床资料,均经药物保守治疗12个月以上无效,阴茎勃起后弯曲畸形,而行阴茎硬结切除自体睾丸鞘膜移植修补缺损治疗.结果 所有患者均得到半年以上的随访,患者术后阴茎均能恢复正常勃起,无勃起疼痛感,能进行满意的性生活,无手术侧睾丸萎缩、扭转或坏死.结论 睾丸鞘膜移植术治疗阴茎Peyronies病造成的阴茎勃起畸形是一种安全、简便、经济和有效的手术方式.     

睾丸、阴茎大小与婚育关系的探讨(附868例报告)

本文报告在1988年做过睾丸、阴茎测量的868例婚前检查男子的婚后性生活和生育情况随访结果。其中婚后性生活不正常占0.58％;新婚夫妇一年内受孕率为89.81％;夫妇同居二年,未采用避孕措施而未曾受孕者50例,不育率为6.21％。简要讨论了睾丸体积,阴茎长度与被访者性生活和生育功能的关系。     

原发性睾丸恶性淋巴瘤7例报告

目的探讨原发性睾丸恶性淋巴瘤的临床规律。方法回顾分析本院诊治的7例原发性睾丸恶性淋巴瘤患的临床资料。结果全组7例均施行根治性睾丸切除，术后5例行化疗和放疗，2例单纯化疗。6例获随访，4例死于肿瘤复发和转移，3例仍存活，生存3年以上2例。结论原发性睾丸恶性淋巴瘤应采用积极综合治疗以提高生存率。     

原发性阴茎恶性淋巴瘤1例报告(附文献24例复习)

目的:探讨原发性阴茎恶性淋巴瘤的早期诊断与治疗。方法:根据1例罕见的原发性阴茎恶性淋巴瘤临床诊治经过,结合文献,对其临床特点、鉴别诊断及治疗方法进行分析。并对病理标本的免疫组化酶标特点在临床诊断中的价值进行分析。结果:手术治疗阴茎、睾丸和阴囊病变,术后予化疗。本例免疫酶标提示CD56+,颗粒酶B、穿孔素阳性;CD3(+/-),表面CD3阴性,胞质CD3ε阳性。结论:阴茎原发性恶性淋巴瘤可行手术、局部放疗、全身化疗的综合治疗方法,深部活检及免疫组化检查是最主要的诊断方法。     

阴茎原发性恶性淋巴瘤1例

患者 ,5 9岁。因发现阴茎进行性增大肿物 3个月余入院。体检 :全身浅表淋巴结无肿大。阴茎腹侧近阴囊处可扪及一 3 .0 cm× 2 .5 cm× 1 .0 cm的质硬肿物 ,局部皮肤无潮红、破溃及发热 ,表面凹凸不平 ,压痛明显 ,与阴茎海绵体和尿道海绵体粘连 ,分界不清 ,不能推动。实验室检查 :血常规白细胞 5 .6× 1 0 9/L,中性分叶核 0 .6 3 ,淋巴细胞 0 .3 7。血沉 5 3mm/h。血清碱性磷酸酶 4u/L。胸部正侧位 X线片未见纵隔淋巴结肿大。 B超 :肝、脾未见异常 ,腹主动脉、髂血管旁淋巴结未见肿大。膀胱镜检查膀胱、尿道内未见肿物。局麻下行肿物穿刺活…     

Follicular large cell lymphoma localized to the testis in children

PURPOSE: Primary follicular lymphoma of the testis in childhood is rare with only 6 cases previously reported. We present 3 additional cases. MATERIALS AND METHODS: We extensively analyzed primary follicular lymphoma of the testis in 3 boys. Clinical data were obtained by reviewing patient charts. RESULTS: The patients were 4, 5 and 11 years old, respectively. Two patients presented with painless unilateral testicular enlargement and 1 presented with unilateral hydrocele. Laboratory findings were within normal limits in all patients. Radical orchiectomy was done in all cases. The excised testes were partially or completely replaced by tumor. In all cases the features were those of follicular, large cell-type malignant lymphoma. Tumor cells in all cases were CD20 and CDw75 positive, focally CD23 positive and bcl-2 negative, while in 2 they were CD10 positive and bcl-6 positive. Surface Ig was absent in the 2 cases studied. Karyotyping in 1 case showed a normal karyotype. Staging revealed no evidence of extratesticular disease. All patients underwent combination chemotherapy and were in complete remission 7 to 59 months after therapy. CONCLUSIONS: We present 3 cases of pediatric primary follicular lymphoma of the testis. Pathological findings and clinical features were similar to those in the 6 previously reported cases and suggest that primary pediatric testicular follicular lymphoma may represent unique subset of follicular lymphoma with a particularly good prognosis.     

Primary anaplastic large cell lymphoma of the testis

Anaplastic large cell lymphoma (ALCL) was first described by Stein et al. in 1985, at that time neoplastic cells were labeled by the monoclonal antibody CD30. ALCL was included as a differentiate entity in the reviewed Kiel and REAL classification. ALCL carries the t (2; 5) (p23; q35) translocation; the absence of ALK kinase from normal lymphoid cells indicates that immunohistochemical expression of ALK is specific for the (2; 5) translocation. This disease is characterized by a diffuse proliferation of large anaplastic cells with kidney-shaped/horse-shoe nuclei. A distinguishing feature is a perinuclear eosinophilic region that represents a prominent Golgi apparatus. These cells are named hallmark-cells being almost pathognomonic. Immunohistochemically the most important features are that tumor cells consistently express CD30 and EMA on the cell membrane and in the Golgi region, while ALK immunostaining is usually both, cytoplasmic and nuclear. To our knowledge only two cases of primary ALCL of the testis have been reported. Hereby we present a case of a typical ALCL expressing ALK and CD30, which presented with subcutaneous nodules and bilateral testicular mass, without systemic involvement.     

Primary anastomosis of the traumatically amputated penis

Penile amputation is an uncommon condition for which immediate surgical replantation is warranted. This work aimed to represent intervention and management for an amputated penis by replantation and reconstruction. A 23-year-old man presented with traumatic penile amputation for 2 h where the penile proximal part was 1 cm far from the pubis. Replantation included end-to-end anastomosis of the urethral mucosa over a catheter, approximation of the corpus cavernosum and tunica albuginea, anastomosis of the deep dorsal vein, dorsal nerve, both dorsal arteries and superficial dorsal vein. At day 5 post-operatively, the replanted penis had preserved capillary filling. The catheter was removed at day 11, where the patient urinated smoothly. The preliminary cosmetic appearance was satisfactory with frequent morning erection, reported night emission twice within the first month post-operatively. Sensation was preserved in the distal anastomosed stump. It is concluded that meticulous microsurgical technique decreases the possibility of skin loss and increases the chance of erectile function.     

Primary adenocarcinoma of the rete testis

We report a case of adenocarcinoma of the rete testis in a 44-year-old man, presented intially with a hydrocele and later with signs of infection in the affected hemiscrotum. Multiple focal lesions within the testis appeared 6 months later in ultrasounds. After high inguinal orchiectomy, histology revealed a primary adenocarcinoma of the rete testis. Adenocarcinoma of the rete testis is a rare a highly malignant tumour originating in the mediastinum of the testis. Slightly over 40 cases have been reported in the literature. The treatment of choice is radical orchiectomy. Prognosis is poor; as mainly as 40% of patients die within the first year of diagnosis.     

Isolated lymphoedema of the external genitalia

Background Lymphoedema of the male genitalia occurs because of obstructed lymphatics. Well-known causes include filariasis or any other inflammatory process producing lymphatic obstruction, malignancy, radiotherapy to or surgery of the pelvis.
Patient Occasionally there is no evident cause as was the case in a 40-year-old patient who is presented in this article.
Method He was treated by excision of all penile skin and application of split thickness skin grafts and, in addition, excision of surplus scrotal skin followed by primary closure of the defects.
Results The patient resumed sexual intercourse 3 months after the operation. A second operation was needed because of a troublesome scar formation. The final result was satisfactory.     

Primary diffuse large B-cell testicular lymphoma: magnetic resonance imaging findings

Testicular lymphoma represents the commonest testicular malignancy in men older than 50 years. MR imaging of the scrotum is an efficient supplemental diagnostic tool in the evaluation of scrotal diseases. We report two cases of primary diffuse large B-cell testicular lymphoma, presented in men over the age of 50 years. MR imaging revealed the presence of a hypointense intratesticular mass lesion on T2-weighted images, strongly and heterogeneously enhancing after gadolinium administration.     

Buried and trapped penis: a case report

While buried penis cases are characterised by congenital normal attachments to penis, trapped penis cases are characterised by insufficiency of penile skin occurring as a complication after surgical operations such as circumcision. Unless diagnosed, circumcision procedures should be avoided in congenital concealed penis cases. Here we present a case of congenital buried penis with deteriorated clinical findings after two circumcision procedures at 1.5 years of age. The surgical treatment applied in this case is discussed.