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1.

Background

Ninety percent of hepatic cancers are hepatocellular carcinomas (HCC) which have an unfavorable prognosis. HCC is a hypervascular tumor supplied mainly by the hepatic artery. It has a higher blood supply than the surrounding hepatic tissue due to neovascularization. Computed tomography with perfusion imaging (CTP) is a non invasive tool which quantifies the blood flow parameters of HCC and compares it to the surrounding tissue.

Purpose

To prove that CTP is a valuable diagnostic tool in diagnosis of HCC and posttherapeutic assessment.

Patients and methods

One hundred and twenty-six HCC patients with 150 focal lesions are enrolled this study. Perfusion parameters are quantified and results are compared to those of triphasic CT.

Results

CTP detected 141 lesions with 94% sensitivity and 40% specificity with elevated arterial perfusion (AP) and perfusion index (PI) with low portal flow (PF). It missed 5 lesions because of their hypovascularity and 4 lesions following radiofrequency ablation (RFA) and trans arterial chemo embolization (TACE).

Conclusion

CTP is a safe and specific imaging tool for diagnosis and assessment of therapeutic interventional procedures in HCC.  相似文献   

2.

Objectives

Comparison between digital mammography alone and with adding digital breast tomosynthesis in breast cancer screening.

Patients & methods

143 females underwent digital mammography, digital breast tomosynthesis and breast ultrasound.

Results

DBT+DM decreased recall rate by 38% in BI-RADS 0. From BI-RADS I till BI-RADS V DBT+DM showed more accuracy than DM. In BI-RADS IV DBT+DM decreased false positive results by 33%.

Conclusion

Adding digital breast tomosynthesis to digital mammography improves the diagnostic accuracy in breast cancer screening.  相似文献   

3.

Objective

To evaluate the additive value of Contrast Enhanced Spectral Mammography (CESM) in the preoperative assessment of malignant lesions in dense breast parenchyma regarding multiplicity.

Material and methods

The study included 160 women having heterogeneous dense breast parenchyma (ACR c and d) with suspicious lesions identified on sono mammography examination. All patients performed contrast enhanced spectral mammography to confirm or exclude lesion multiplicity. The number of lesions was calculated in the contrast high energy subtraction images with the reference standard being histopathological analysis.

Results

Adding CESM to sono-mammography the accuracy in identifying multiple malignant lesion increased from 81.8% accuracy of sono-mammography up to 100% accuracy after adding CESM.

Conclusion

Contrast enhanced spectral mammogram showed an added value in the preoperative assessment of breast masses increasing the accuracy of detection of lesions and multiplicity (multifocality and multi-centricity).  相似文献   

4.

Objectives

To assess the technical success and short term clinical efficacy of trans-catheter ovarian vein coiling in the treatment of symptomatic pelvic congestion syndrome in women.

Methods

This study included 10 female patients having pelvic venous congestion treated by coiling and were followed up for 3?months between February 2016 and April 2017 at Ain Shams University hospital, Cairo, Egypt. Symptomatology of pelvic congestion syndrome that was documented either by transvaginal Doppler and/or by MRI with no response to conservative treatment.

Results

Symptoms successfully disappeared in 8 patients out of 10. Partial relief of symptoms in one patient that was then disappeared after another session. Only one patient showed no improvement.

Conclusion

Our study demonstrates high efficacy of ovarian vein coiling as a new technique in the treatment of symptomatic female patients with pelvic congestion syndrome.  相似文献   

5.
6.

Purpose

To highlight the relationship between coraco-humeral distance and subscapularis tendon tear.

Material and methods

Sixty-two shoulder MRI studies were examined. Twenty-two patients had partial or complete tear of subscapularis tendon and forty shoulder as a control group. Axial and oblique sagittal MR images were examined to measure the coraco-humeral distance followed by statistical analysis to correlate the distance with tendon tear.

Results

A cut-off value of 8.25?mm for the coraco-humeral distance gave a sensitivity of 77.5% and specificity of 72.7% for subscapularis tendon tear.

Conclusion

There is a well-known relationship between the coraco-humeral distance and the subscapularis tendon tear and its meticulous assessment in subjects with pain in the anterior shoulder region increases the diagnosis of subcoracoid impingement.  相似文献   

7.

Aim of the work

To evaluate the role of diffusion weighted imaging (DWI) in the planning for CT guided biopsy of lung and mediastinal lesions.

Subjects and methods

This cross sectional study included 23 patients with mean age was 42.7?years came with clinical and imaging suspicion of chest malignancy, referred for CT guided transthoracic biopsy. DWI and apparent diffusion coefficient (ADC) were evaluated for all patients to choose the area of maximum restriction.

Results

The study showed that with DWI guidance; all the biopsy specimens were diagnostic and provide adequate material for analysis.

Conclusion

DWI and measurement of ADC value has a very helpful role in the pre-procedural planning of transthoracic biopsies.  相似文献   

8.

Aim of the work

The aim of this retrospective study is to highlight the MDCT features of portal biliopathy (PB).

Patients

This study included 32 patients with extra-hepatic portal vein obstruction (EHPVO) and biliary dilatation. Their age ranged from 27 to 63?years, including 21 males and 11 females.

Methods

The included patients had records of complete clinical examination and laboratory data, including bilirubin levels. All patients were examined by multiphase MDCT study with good portal phase.

Results

Extra-hepatic biliary dilatation without intra-hepatic dilatation seen in 5 patients (type I), intra-hepatic dilatation without extra-hepatic dilatation seen in 12 (type II) patients, unilateral intra-hepatic predominant with extra-hepatic dilatation (type IIIA) seen in 7 patients (4 right sided predominance and 3 left sided predominance). Both extra and bilateral intra-hepatic dilatation in 8 patients (type IIIB).

Conclusion

MDCT is an excellent technique for the diagnosis of portal biliopathy reducing errors in diagnosis.  相似文献   

9.

Objectives

To evaluate the efficacy and safety of percutaneous cholecystostomy (PC) in management of acute cholecystitis in elderly patients.

Methods

Retrospective study of elderly patients (age?≥?60?years) undergoing Ultrasound-guided PC for acute cholecystitis, over a period of two years. Patients were reviewed for demographic features, co-morbidity, resolution of symptoms and outcome and complications.

Results

Seventeen patients (11 women, 6 men; mean age, 66?±?7?years) underwent PC for acute cholecystitis. PC was technically successful in all patients and showed positive clinical response within 72?h in 15 patients (88.2%). Complications of PC tube placement occurred in 2 (11.8%) of 17 patients, including bile leakage around the skin in 1 patient ,tube dislodgment in another one and were treated effectively with drain replacement.

Conclusion

Percutaneous cholecystostomy is a safe, effective and technically achievable procedure for treating elderly high-risk patients who present with acute cholecystitis.  相似文献   

10.

Objective

To assess the role of multislice computed tomography (MSCT) in the diagnosis of mesenteric vascular occlusion.

Patients and methods

This study was performed on 30 patients clinically suspected and radiologically confirmed to have mesenteric vascular occlusion, they were examined with 64 row MSCT and were evaluated for evidence of bowel wall changes and abnormal mesenteric vascular changes.

Results

We found that the most prevalent MSCT findings were bowel wall thickening followed by diminished wall enhancement. MSCT gave an accurate diagnosis of the cause of mesenteric vascular occlusion as proved by the final diagnosis based on surgical exploration, laboratory investigations and clinical follow-up.

Conclusion

MSCT is accurate, fast and non invasive technique which should be used in clinically suspected patients with MVO in order to confirm the diagnosis, identify the aetiology and in addition assessing the bowel loop status for adequate management with good prognosis.  相似文献   

11.

Introduction

Endometrial polyps are a common cause of abnormal uterine bleeding. Ultrasound is the most accepted investigation to evaluate them. However, the diagnosis can be difficult and even missed on transabdominal and grayscale imaging. Our study aims to assess the evaluation of endometrial polyps on transvaginal color Doppler.

Patients and methods

A prospective study with performance of transvaginal Doppler and saline infusion sonohysterography with histopathological correlation.

Results

The pedicle artery sign on transvaginal color Doppler sonography was found to have sensitivity of 86.67%, accuracy of 86.67% and positive predictive value of 100%.

Conclusion

Addition of Doppler to transvaginal sonography and Saline infusion Sonohysterography improves characterization and diagnosis of endometrial lesions.  相似文献   

12.

Background

Assessment of treatment response in patients with a brain tumor is paramount, as true tumor recurrence and radiation necrosis are similar looking on conventional MRI.

Purpose

To evaluate the role of dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging in the differentiation between recurrent brain tumors and radiation necrosis.

Material and Methods

Twenty patients with a history of operated primary brain tumors and postoperative radiotherapy with or without chemotherapy were enrolled in this prospective study having conventional MRI findings of enhancing lesion suspicious of being recurrence or radiation necrosis. All patients were examined by DSC-perfusion MRI. Definitive diagnosis was reached through either subsequent surgical biopsy or follow up over 6-12 months.

Results

Fifteen patients (75%) were diagnosed as tumor recurrence and 5 patients as radiation necrosis (25%). The relative cerebral blood volume (rCBV) and relative peak height (rPH) were significantly higher (P?<?0.05) in recurrent tumors than in radiation necrosis lesions. The rCBV and rPH thresholds in differentiating between them were 1.8 and 1.22 respectively with 87%, 93% sensitivity and 100% specificity for each respectively.

Conclusions

DSC-perfusion MRI is a valuable non-invasive tool besides conventional MRI whenever available to differentiate between radiation injury changes and tumor recurrence.  相似文献   

13.

Objectives

To assess the clinical utility of PET-CT in assessment of thoracic involvement in lymphoma patients prior to, during and after finishing treatment and comparing it to contrast enhanced CT (CECT).

Patients and methods

PET-CT was performed for 30 patients with lymphoma. Thoracic nodal and extranodal involvement was assessed and compared to contrast enhanced CT.

Results

Comparison of CECT and PET-CT in staging and assessment of treatment response reveals significant statistical difference (P?=?.0001 & .04 respectively). CECT shows sensitivity?=?83.3% and specificity?=?75% in evaluation of patients after finishing chemotherapy.

Conclusion

PET-CT plays an important role in staging, detection of response to treatment and restaging of lymphoma after finishing chemotherapy.  相似文献   

14.
The aim of this prospective study was to evaluate the diagnostic performance of the use of strain index ratio by sonoelastography to differentiate between benign and malignant breast lesions.

Patients & Methods

This prospective study including 40 females, complaining of breast masses which were suspicious to be malignant on clinical examination. All patients were submitted to B-mode Ultrasound and sonoelastography. Biopsy as a gold standard and pathological study were done for all breast lesions.

Results

US examination of every mass was done and categorized according to BI-RADS categories according to ACR2013, according to US lexicon. Sonoelastography examination with Lesions classification was performed on the basis of a 5-point scoring method proposed by Tsukuba elasticity score. Then measurements of strain ratio were done. Statistical analysis of combination of the three methods was sensitivity of 96.7%, specificity of 100% when we use cut off value of 3–4 in elastography score and ≤3 cut off value of strain ratio.

Conclusion

The combined use of strain ratio with Tsukuba score and BI-RADS categorization increased the diagnostic performance in differentiation between benign and malignant breast lesions.  相似文献   

15.

Objectives

To evaluate accuracy of computed tomography angiography (CTA) in evaluation of post traumatic renal vascular injury.

Patients and methods

38 patients were presented with post traumatic intermittent or persistent hematuria. Renal CTA and digital subtraction angiography (DSA) were done for all patients.

Results

CTA demonstrated pseudoaneurysm (PA) in 30 patients (78.9%) and no vascular lesions in 8 patient (21.1%). CTA had 86.11% sensitivity and 50% specificity in detection of post traumatic renal pseudoaneurysms, CTA missed diagnosis of renal arteriovenous fistula (RAVF) in 10 patients which discovered later by DSA.

Conclusion

CTA with MIP as non invasive technique widely replaced renal DSA in detection of posttraumatic renal pseudoaneurysm. Renal DSA is still best modality in detection of RAVF and also has the upper hand in planning of selective renal artery embolization for the management of persistent or delayed hemorrhage from renal vessels.  相似文献   

16.

Introduction

To determine whether Computed Tomography Perfusion (CTP) can predict treatment response and prognosis in non-small cell lung cancers (NSCLC). To determine which one of the perfusion parameter correlated best with treatment outcome.

Methods

Sixteen patients with NSCLC underwent CTP before and after completion of chemo-radiotherapy. Patients with complete and partial response were grouped as responders and patients with stable and progressive disease were grouped as non-responders. Pre and post-treatment whole tumour perfusion parameters (blood flow - BF, blood volume - BV, mean transit time - MTT and permeability surface area product - PS) were compared between responders and non-responders.

Results

Responders had higher baseline BF and PS values than non-responders; P?=?0.047, 0.028 respectively. On 1?year follow up, patients with even 2.65% increase in PS value from baseline developed metastasis while patients with decrease in PS value by 24% did not develop metastasis (P?=?0.05). Greater decrease in BF values (17%) were noted among responders than non-responders (2.4%) following chemoradiation, though the results were not statistically significant (P?>?0.05).

Conclusions

Tumours with higher baseline BF and PS respond well to chemo-radiation. Changes in the PS values can predict the development of metastasis and hence, the long term outcome.  相似文献   

17.

Purpose

The aim is to assess the usefulness of cine phase-contrast MRI for evaluation of patency of endoscopic third ventriculostomy operation and correlation with clinical state postoperatively.

Material & methods

Prospective study performed upon 20 patients who underwent ETV operation, concerned on obstructive hydrocephalus (age range, 4–63 years; 11 male & 9 Female). Cine PC-MRI CSF flowmetry technique was applied for qualitative and quantitative assessment of CSF flow dynamics through ETV stoma to assess its patency.

Results

The patency of ETV stoma was evaluated according to overall flow amplitude (OFA) as it was the most effective variable to predict the response to surgery, we found that when OFA value is ≥75?μL, the sensitivity and specificity of our technique to determine patient improvement were 71.4% and 76.9%, respectively.According to OFA, we classified the state of ETV stoma into three subcategories: patent stoma with adequate flow; OFA value ≥75?μL (10 patients), patent stoma with low flow; OFA value from 25 up to <75?μL (4 patients) and obstructed stoma with impaired flow; OFA value <25?μL (6 patients).

Conclusion

Cine phase-contrast MR imaging is an effective and reliable method for evaluation and follow up of the ETV patients postoperatively.  相似文献   

18.

Objective

To assess the diagnostic accuracy of diffusion weighted imaging (DWI-MRI) being a non-contrast based MR sequence versus dynamic contrast enhanced MRI (DCE-MRI) in the preoperative loco-regional staging of the cervical carcinoma.

Methodology

Fifty cases of proved cancer cervix prior staging subjected to dynamic post contrast technique: one pre-and six post contrast phases (40?s each). DWI was scanned using different b values and ADC values were measured.

Results

DWI was the most accurate in staging operable cases (93.3%).Parametrial infiltration was overestimated in 3 cases versus 4 cases in DCE-MR. DWI showed 100% sensitivity, positive predictive value and accuracy in the assessment of locally advanced carcinomas. In metastatic lymph nodes, DCE-MR showed the least accuracy of 86%.

Conclusion

DWI is helpful in discriminating local from locally advanced cervical carcinomas. DCE-MR can delineate cervical carcinomas confined to the uterus and exclude bladder/rectal invasion.  相似文献   

19.

Aim of work

To evaluate the role of ultrasound and color Doppler in diagnoses and predicting the outcome of necrotising enterocolitis patients at neonatal ICU.

Subjects and methods

Thirty neonates clinically diagnosed with NEC were examined, 51 ultrasound examinations were done including color Doppler sonography and findings were compared with laboratory data, clinical picture, staging, abdominal radiography and patient's outcome.

Results

Bloody stools and abdominal discoloration correlated with highest risk, low PH and neutropenia and increased DAAS score matched poor outcome. echoegnic free fluid, thin bowel wall, absent wall perfusion, aprestalsis, dilated anechoic bowel, increased bowel perfusion and pneumatoses intestinalis matched adverse outcome. sonographic signs of pneumatoses intestinalis interrelated with radiographic signs.

Conclusion

US was found to be highly sensitive and specific in diagnosing, staging and predicting the outcome of NEC patients, based on group of findings that were categorized per their risk ratio and correlated with outcome.  相似文献   

20.

Objectives

To evaluate the reliability of diffusion-weighted imaging (DWI) in evaluating kidney changes after extracorporeal shock wave lithotripsy (ESWL) treatment for kidney stones.

Patients and methods

This prospective study included 28 patients who subjected to ESWL treatment for renal stones. Color Doppler ultrasonography (CDUS) and DWI were achieved before and within one day after ESWL. Follow up DWI also performed 2?weeks after ESWL. DWI was performed with b factors of 0, 500 and 1000?s/mm2 at 1.5?T MRI. For each patient, the Resistive index (RI) and ADC values were calculated for both the affected and contralateral kidneys.

Results

The ADC values of the treated kidneys were lower in all three poles of the kidney compared with ADC values done before ESWL and in comparison with the contra lateral un-treated kidney. The RI showed no significant difference in the three poles of treated and untreated kidneys before and after with ESWL (p?>?0.05).

Conclusion

DWI is a reliable method in detecting renal changes after ESWL treatment that can give prediction about kidney changes produced by shock waves.  相似文献   

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