共查询到20条相似文献，搜索用时 15 毫秒
1.
Cosgrove DO Berg WA Doré CJ Skyba DM Henry JP Gay J Cohen-Bacrie C;BE Study Group 《European radiology》2012,22(5):1023-1032
Objectives
To evaluate intra- and interobserver reproducibility of shear wave elastography (SWE) for breast masses.Methods
For intraobserver reproducibility, each observer obtained three consecutive SWE images of 758 masses that were visible on ultrasound. 144 (19%) were malignant. Weighted kappa was used to assess the agreement of qualitative elastographic features; the reliability of quantitative measurements was assessed by intraclass correlation coefficients (ICC). For the interobserver reproducibility, a blinded observer reviewed images and agreement on features was determined.Results
Mean age was 50 years; mean mass size was 13 mm. Qualitatively, SWE images were at least reasonably similar for 666/758 (87.9%). Intraclass correlation for SWE diameter, area and perimeter was almost perfect (ICC?≥?0.94). Intraobserver reliability for maximum and mean elasticity was almost perfect (ICC?=?0.84 and 0.87) and was substantial for the ratio of mass-to-fat elasticity (ICC?=?0.77). Interobserver agreement was moderate for SWE homogeneity (κ?=?0.57), substantial for qualitative colour assessment of maximum elasticity (κ?=?0.66), fair for SWE shape (κ?=?0.40), fair for B-mode mass margins (κ?=?0.38), and moderate for B-mode mass shape (κ?=?0.58), orientation (κ?=?0.53) and BI-RADS assessment (κ?=?0.59).Conclusions
SWE is highly reproducible for assessing elastographic features of breast masses within and across observers. SWE interpretation is at least as consistent as that of BI-RADS ultrasound B-mode features.Key Points
? Shear wave ultrasound elastography can measure the stiffness of breast tissue ? It provides a qualitatively and quantitatively interpretable colour-coded map of tissue stiffness ? Intraobserver reproducibility of SWE is almost perfect while intraobserver reproducibility of SWE proved to be moderate to substantial ? The most reproducible SWE features between observers were SWE image homogeneity and maximum elasticity2.
Mohamed H. Zahran Mohamed M. El-Shafei Doaa M. Emara Samar M. Eshiba 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(1):249-258
Introduction
Elastography is considered a non-invasive imaging modality which determines the tumors according to their stiffness. Strain images representing the stiffness of the lesions compared to that of the surrounding normal tissue.Purpose
To prospectively evaluate the sensitivity and specificity of the real-time sonoelastography together with B-mode US for distinguishing benign from malignant breast lesions.Methods
The study was conducted on 80 patients, each patient was subjected to complete history taking, thorough clinical examination. All patients had conventional US and elastography using Hitachi 7.5?MHz linear probe (Hitachi hi vision avirus ultrasound), while only in 68 patients mammography was done.Results
Among the 80 patients, sensitivity and specificity of the elastography test of breast lesions according to the elastography score were 80% and 80.95% respectively, while sensitivity and specificity of conventional B mode US were 80% and 76% respectively and the combined B mode US and US elastography showed higher sensitivity and specificity of 86.6% and 90.4% respectively.Conclusion
Elastography is a non-invasive imaging technique which is done in the same session of ultrasound in an attempt to increase and improve the accuracy of diagnostic efficiency of ultrasound. 相似文献3.
Objectives
To investigate whether mass stiffness measured by shear-wave elastography (SWE) can predict the histological upgrade of ductal carcinoma in situ (DCIS) confirmed through ultrasound (US)-guided core needle biopsy (CNB).Methods
The institutional review board approved this study and informed consent was waived. A database search revealed 120 biopsy-confirmed DCIS in patients who underwent B-mode US and SWE prior to surgery. Clinicopathologic results, B-mode findings, size on US, and mean and maximum elasticity values on SWE were recorded. Associations between upgrade to invasive cancer and B-mode US findings, SWE information, and clinical variables were assessed using univariate, multivariate logistic regression, and multiple linear regression analysis.Results
The overall upgrade rate was 41.7 % (50/120). Mean stiffness value (P?=?.014) and mass size (P?=?.001) were significantly correlated with histological upgrade. The optimal cut-off value of mean stiffness value, yielding the maximal sum of sensitivity and specificity, was 70.7 kPa showing sensitivity of 72 % and specificity of 65.7 % for detecting invasiveness. Qualitative elasticity colour scores were significantly correlated with the histological upgrade, mammographic density, and B-mode category (P?<?.04).Conclusion
Mean stiffness values evaluated through SWE can be utilized as a preoperative predictor of histological upgrade to invasive cancer in DCIS confirmed at US-guided needle biopsy.Key Points
? Higher stiffness values were noted in invasive cancer than DCIS. ? Qualitative SWE colour scores significantly correlated with the histological upgrade. ? Qualitative SWE colour scores had excellent interobserver agreement.4.
Mahmoud Abd Elaziz Dawood Noha Mohamed AbdelMaboud Ibrahim Haytham Haroun Elsaeed Nancy Gamal Hegazy 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(1):265-271
The aim of this prospective study was to evaluate the diagnostic performance of the use of strain index ratio by sonoelastography to differentiate between benign and malignant breast lesions.
Patients & Methods
This prospective study including 40 females, complaining of breast masses which were suspicious to be malignant on clinical examination. All patients were submitted to B-mode Ultrasound and sonoelastography. Biopsy as a gold standard and pathological study were done for all breast lesions.Results
US examination of every mass was done and categorized according to BI-RADS categories according to ACR2013, according to US lexicon. Sonoelastography examination with Lesions classification was performed on the basis of a 5-point scoring method proposed by Tsukuba elasticity score. Then measurements of strain ratio were done. Statistical analysis of combination of the three methods was sensitivity of 96.7%, specificity of 100% when we use cut off value of 3–4 in elastography score and ≤3 cut off value of strain ratio.Conclusion
The combined use of strain ratio with Tsukuba score and BI-RADS categorization increased the diagnostic performance in differentiation between benign and malignant breast lesions. 相似文献5.
Ahmed Ebraheem Ebeed Marwa Abd El-hamied Romeih Medhat Mohamed Refat Nehad Mohamed Salah 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):603-610
Purpose
To evaluate the role of ultrasound elastography, Doppler and micropure imaging in the assessment of thyroid nodules, using the pathological analysis as the reference standard.Patients and methods
A prospective study was carried on all patients referred to radio-diagnosis department at Tanta Cancer Centre between November 2015 and November 2016 for evaluation of undiagnosed thyroid nodules. All patients were examined by B-mode ultrasound, color Doppler, micropure imaging and ultrasound elastography. All thyroid nodules were subjected to fine-needle aspiration biopsy.Results
90 patients (78 women, 12 men) with 159 incompletely diagnosed thyroid nodules. 24 nodules were malignant and 135 nodules were benign, micro calcification was detected by micropure imaging in 40 nodules (29.6%) in the benign thyroid nodules and in 20 nodules (83.3%) in the malignant thyroid nodules (sensitivity 83.3%, specificity 70.4%, and accuracy 84.9%). Color flow Doppler (type III) with marked intranodular and absent or slight perinodular blood flow, was detected in 19 malignant nodules, with sensitivity 79.2%, specificity 95.6%, and the overall accuracy rate was 88.7%. The predictivity of ultrasound elastographic score measurement has high sensitivity 87.5%, and specificity 91.1%, Strain elastography cutoff value for malignant nodules was 2.7 (Sensitivity 83.3% and specificity 91.1%).Conclusion
Elastography and micropure imaging technique are useful imaging modalities to detect the nature of thyroid nodules. In combination with Doppler and B-mode sonography, they could give a better assessment for undiagnosed thyroid nodules. 相似文献6.
Ji Hyun Youk Hye Mi Gweon Eun Ju Son Jin Chung Jeong-Ah Kim Eun-kyung Kim 《European radiology》2013,23(6):1519-1527
Objectives
To evaluate the interobserver agreement and the diagnostic performance of 3D shear-wave elastography (SWE) for breast lesions in comparison with 2D SWE.Methods
A total of 163 breast lesions (malignant 48, benign 115) in 146 women who underwent B-mode ultrasound and SWE before biopsy were included. Two radiologists reviewed six data sets (B-mode, SWE, and a combination of both for 2D and 3D ultrasound). B-mode and SWE features were recorded. BI-RADS category was assigned for B-mode and combined sets. Interobserver variability was assessed using the κ statistic. Diagnostic performance of each data set was evaluated using the area under the ROC curve (AUC).Results
SWE showed substantial to almost perfect agreement, with Ehomo in 2D SWE being higher than in 3D SWE. The AUC of 2D SWE was higher than 3D SWE for all SWE features, significantly so for Ecol (0.933 vs. 0.867, P?=?0.002) and Emax (0.961 vs. 0.874, P?=?0.006). After adding SWE to B-mode ultrasound, the AUC in 2D ultrasound increased significantly (0.968 vs. 0.912, P?=?0.008), but 3D ultrasound showed no significant difference (0.966 vs. 0.935; P?=?0.07).Conclusion
For 3D SWE, interobserver agreement was good, but the diagnostic performance was inferior to 2D SWE even after adding to B-mode ultrasound.Key Points
? Shear-wave elastography (SWE) provides further diagnostic information during breast ultrasound. ? 3D SWE diagnostic performance is inferior to 2D SWE. ? In 3D SWE, interobserver agreement was good. ? 2D B-mode ultrasound showed significant diagnostic improvement when combined with 2D SWE. ? 3D B-mode ultrasound performance was not significantly improved when combined with 3D SWE. 相似文献7.
Ayman M.A.M. Nada Rashad Hamdi Ahmed Shokry 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1179-1186
Purpose
To evaluate the value of dual energy contrast enhanced (DECE) soft tissue digital mammography and ultrasound elastography (UE) in the detection of breast lesions and discrimination between benign and malignant ones.Patients and methods
32 female patients with breast lesions were prospectively evaluated at the female imaging unit of Diagnostic and Interventional Radiology Department of the National Cancer Institute, Cairo University. Routine sono-mammography was done for each patient then these patients were submitted to DECE soft tissue digital mammography as well as UE.The DECE digital mammography scans were held via GE Senographe 2000D “GE Healthcare; Chalfont St-Giles, UK” FFDM system with some specific software and hardware adaptations.The UE exams were held on ultrasound scanner with elastography unit and 7.5?Mhz linear array electronic probe (Hitachi digital, EUB- 7500; Hitachi medical, Tokyo, Japan).Results
This study showed that sensitivity and specificity of DECE soft tissue digital mammography and UE were 86.3%, 60% and 80.9%, 40% respectively.Conclusion
DECE soft tissue digital mammography demonstrated significant increase in the sensitivity without a loss in specificity. DECE soft tissue digital mammography is fast-reproducible imaging tool without operator dependency. DECE soft tissue digital mammography and UE are valuable tools to evaluate equivocal lesions. 相似文献8.
Maha Helal Manal F. Abu Samra Mohammed A. Ibraheem Asmaa Salama Ebtesam Esmail Hassan Nour El-Huda Hassan 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):741-750
Aim
Assess accuracy of contrast enhanced spectral mammography (CESM) versus conventional mammography and ultrasound in evaluation of BI-RADS 3 and 4 breast lesions with pathological correlation.Patients and methods
Thirty female patients with 35 breast lesions diagnosed by conventional imaging as BI-RADS 3 and 4, presented to Women’s Imaging Unit of Radiology Department between January and December 2015, age ranged from 23 to 70 years. All patients underwent conventional mammography and ultrasound then CESM.Results
Patients divided into two groups, benign and malignant lesions group according to histological analysis. Mammography results that malignant lesions detected in 18/35 (51.4%) while benign lesions 17/35 (48.6%). Ultrasound revealed 27/35 (77.1%) lesions were malignant and 8/35 (22.9%) lesions benign. But CESM, revealed 25/35 (71.4%) lesions were malignant & 10/35 (28.6%) lesions benign. Among 7 patients with multifocal/ multi-centric histologically proven malignant lesions, all detected by CESM 7/7 cases (100%) versus 2/7 cases (28.6%) and 6/7 cases (85.7%) detected by mammography and ultrasound respectively. Based on, CESM had 95.2% sensitivity and 82.9% diagnostic accuracy.Conclusion
CESM has better diagnostic accuracy than mammography alone and mammography plus ultrasound. CESM has 82.9% diagnostic accuracy in comparison to 51.4% for mammography and 77.1% for ultrasound. 相似文献9.
Amr Farouk Ibrahim Moustafa Eman Faker Kamal Maher M. Hassan Mona Sakr Mohammed Mohammed Mohammed Gomaa 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(1):259-264
Objective
To evaluate the additive value of Contrast Enhanced Spectral Mammography (CESM) in the preoperative assessment of malignant lesions in dense breast parenchyma regarding multiplicity.Material and methods
The study included 160 women having heterogeneous dense breast parenchyma (ACR c and d) with suspicious lesions identified on sono mammography examination. All patients performed contrast enhanced spectral mammography to confirm or exclude lesion multiplicity. The number of lesions was calculated in the contrast high energy subtraction images with the reference standard being histopathological analysis.Results
Adding CESM to sono-mammography the accuracy in identifying multiple malignant lesion increased from 81.8% accuracy of sono-mammography up to 100% accuracy after adding CESM.Conclusion
Contrast enhanced spectral mammogram showed an added value in the preoperative assessment of breast masses increasing the accuracy of detection of lesions and multiplicity (multifocality and multi-centricity). 相似文献10.
Hanan S. Gewefel 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(1):285-292
Background
Ultrasound and mammography alone may not always identify malignant breast lesions. Samsung Medison has added the Smart detect? (S-detect?) program to its ultrasound features, and this may improve the identification of benign and malignant breast lesions.Objective
To evaluate the accuracy of S-detect?, a new ultrasound added feature, and to identify benign and malignant breast lesions in women with symptoms or signs of focal breast disease.Methods
In a pilot study, the registered data of a selected 45 women is retrospectively audited and analyzed. These women, presenting with clinical symptoms of breast disease (diagnostic), were examined by mammography and ultrasound. The interpretation and Hand Held Ultrasound (HHUS) have been done with 2 radiologists determining the BIRADS® classification results for every woman (benign or malignant). In addition, S-detect? was applied during the ultrasound examination, and S-detect? findings (benign or malignant) were recorded in either concordance or discordance with radiologists’ findings. Biopsy was performed as a gold standard.Results
Among the enrolled 45 women in the study, 33 (73.3%) had concordant results with the radiologists while the remaining 12 (26.6%) were discordant, in 10 (22.2%) of the 12 discordant cases, S-detect? findings of benign contradicted radiologists’ findings and in 2 of the cases, S-detect? findings of malignant contradicted radiologists’ findings. In the 10 discordant cases where S-detect? recommended benign, only 2 were correct, but in the 2 discordant cases where S-detect? recommended malignant, both were correct. The overall accuracy of S-detect? was 82.22%, sensitivity 61.90%, but a specificity was 100%.Conclusion
The use of S-detect? in this study identified additional cases of malignancy, so this technology may be a useful tool in addition to mammography and US for the diagnosis of breast disease. The specificity of the S-detect? in this study is remarkably high; yet, the sensitivity is low. Despite a small number of cases, we suggest a larger scale study, to validate the clinical utility in using the B-mode plus S-detect? to enhance diagnosis in patients presenting with symptoms and signs of breast diseases. 相似文献11.
Su Hyun Lee Jung Min Chang Won Hwa Kim Min Sun Bae Nariya Cho Ann Yi Hye Ryoung Koo Seung Ja Kim Jin You Kim Woo Kyung Moon 《European radiology》2013,23(4):1015-1026
Objectives
To prospectively compare the diagnostic performances of two-dimensional (2D) and three-dimensional (3D) shear-wave elastography (SWE) for differentiating benign from malignant breast masses.Methods
B-mode ultrasound and SWE were performed for 134 consecutive women with 144 breast masses before biopsy. Quantitative elasticity values (maximum and mean elasticity in the stiffest portion of mass, Emax and Emean; lesion-to-fat elasticity ratio, Erat) were measured with both 2D and 3D SWE. The area under the receiver operating characteristic curve (AUC), sensitivity and specificity of B-mode, 2D, 3D SWE and combined data of B-mode and SWE were compared.Results
Sixty-seven of the 144 breast masses (47 %) were malignant. Overall, higher elasticity values of 3D SWE than 2D SWE were noted for both benign and malignant masses. The AUC for 2D and 3D SWE were not significantly different: Emean, 0.938 vs 0.928; Emax, 0.939 vs 0.930; Erat, 0.907 vs 0.871. Either 2D or 3D SWE significantly improved the specificity of B-mode ultrasound from 29.9 % (23 of 77) up to 71.4 % (55 of 77) and 63.6 % (49 of 77) without a significant change in sensitivity.Conclusion
Two-dimensional and 3D SWE performed equally in distinguishing benign from malignant masses and both techniques improved the specificity of B-mode ultrasound.Key Points
? Shear-wave elastography (SWE) is increasingly used during ultrasound of the breast ? 2D and 3D SWE performed equally in distinguishing benign from malignant masses ? Either SWE method, combined with B-mode, outperformed B-mode ultrasound alone ? Quantitative elasticity was greater for 3D than 2D SWE for all masses 相似文献12.
Doaa M. Emara Mohamed M. El Shafei Hoda M. Abdel Naby 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(2):408-414
Objective
The aim of this study was to assess the accuracy of ultrasound elastography as a recent imaging technique in diagnosis of CTS and evaluation of its severity in patients suffering clinically compared to the results of the gold standard electrophysiological tests.Materials and methods
This was a prospective cross sectional study included 100 patients clinically diagnosed as having unilateral idiopathic CTS (90% of the dominant hand), referred to radiology department from physical medicine department at Alexandria main university hospital from June 2015 till May 2016 after being evaluated electrophysiologically for correlation with the data of the ultrasound and ultrasound elastography of the median nerve. A control group of 100 patients with no wrist or hand complain were included in the study.Results
As diagnosed electrophysiologically, there were 44 (44%), 35 (35%) and 21 (21%) patients with mild, moderate and severe degree of CTS respectively. The mean cross sectional area of the median nerve among the studied cases was 12.19?±?1.59?mm2 while the mean strain ratio of the median nerve by ultrasound elastography was 2.20 (1.0–5.0).Conclusion
In addition to electrophysiological study, ultrasound and ultrasound elastography are valuable tools for the diagnosis and classification of CTS. 相似文献13.
Enas A. Azab Marwa E. Ibrahim 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(2):564-570
Introduction
Diffusion-weighted imaging (DWI) is a modality that depicts the diffusivity of water molecules. This technique has the potential to play an adjunct role to conventional and dynamic MRI in the assessment of breast tissue.Aim of work
To evaluate the role of DWI with absolute and normalized ADC value measurements in characterization of breast lesions.Patients and methods
Seventy patients with mass or non mass lesions on mammography or breast ultrasound were included in this study. DWI were added to routine MR study with calculation of ADC absolute value and normalized ratio for lesions before biopsy of their breast lesions and results were correlated with histopathology.Results
Thirty out of 70 detected lesions were malignant. Malignant lesions showed lower ADC values and lower ratio of normalized ADC than benign lesions. The ROC study revealed that a cutoff ADC value of 1.1?×?10?3?mm2/s and normalized ADC ratio of 0.9 had high sensitivity of 89.75%, and 92.2% with specificity of 94.4% and 94.4% respectively in the differentiation between benign and malignant breast lesions.Conclusion
DWI is a short unenhanced scan that can be potential adjunct to conventional breast MRI and can be used to accurately characterize breast lesions with high sensitivity and specificity Suggested. 相似文献14.
Noha Mohamed Osman Enas Abdel Ghany Nivine Chalabi 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(4):1182-1186
Objectives
We aimed to compare the recall rate (RR) and the cancer detection rate (CDR) of combined full field digital mammography and digital breast tomosynthesis (FFDM?+?DBT) to those of full field digital mammography (FFDM) alone in breast cancer survivors.Methods
We enrolled 146 female breast cancer survivors schedule. All patients underwent FFDM and DBT in the same setting. Results of FFDM alone were compared to those of FFDM?+?DBT regarding patients' RR and CDR.Sensitivity, specificity, accuracy, positive and negative predictive values were also calculated for FFDM alone and for FFDM?+?DBT in detecting breast cancer lesions.Results
Our results showed that FFDM?+?DBT decreased patients' RR by 3.4% and increased the CDR by 4.1%. Reduction in RR was evident in higher breast densities. FFDM mammography had 18 false negative lesions and 29 false positives. Sensitivity, specificity, accuracy, NPV and PPV in detecting breast lesions were: 84.2%, 53.1%, 64.0%, 86.7% and 48.9% for FFDM compared to 100%, 92.1%, 95.3%, 100% and 89.7% for FFDM?+?DBT.Conclusion
Combined FFDM?+?DBT in the post breast cancer surveillance regimen has shown to reduce the patients' RR and to increase the CDR. FFDM?+?DBT had higher diagnostic accuracy than FFDM alone. FFDM?+?DBT ought to be a standard combination in the breast cancer surveillance in treated patients. 相似文献15.
Mai E.M. Khamis Ahmad Abdel Azim Ismail Ahmed M. Alaa El-deen Mohamed Farouk Amin 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):913-920
Objective
To detect if strain ultrasound elastography and strain ratio have additional value to the conventional grey scale ultrasound in predicting thyroid malignancy.Patients and methods
This study included 92 thyroid nodules from 62 patients (the mean age was 40.64?±?13.93). Morphologic aspects of the thyroid nodule in conventional grey scale ultrasonography and elastographic examinations with elastography score and strain ratio (SR) were performed for all nodules. The final diagnosis was confirmed by fine needle aspiration biopsies in 72 nodules and by excisional biopsies in 20 nodules.Results
We found that combination of both conventional ultrasound and strain elastography score have the best diagnostic performance with sensitivity, specificity, PPV, NPV and accuracy accounting for 80%, 97%, 57%, 99% and 96% respectively. The means SR for benign nodules (1.37?±?0.56) was significantly lower than that for malignant nodules (3.0?±?0.71) [p-value .003].The optimal SR cutoff is 2.5 with estimated 80% sensitivity, 98% specificity, PPV 67%, NPV 99% and accuracy 97%.Conclusion
The clinical application of elastography score and SR should be carried out hand in hand with conventional sonographic assessment of thyroid nodules to achieve the best diagnostic performance. 相似文献16.
Rehab Abdel Rahman El Bakry 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(2):529-535
Objectives
Comparison between digital mammography alone and with adding digital breast tomosynthesis in breast cancer screening.Patients & methods
143 females underwent digital mammography, digital breast tomosynthesis and breast ultrasound.Results
DBT+DM decreased recall rate by 38% in BI-RADS 0. From BI-RADS I till BI-RADS V DBT+DM showed more accuracy than DM. In BI-RADS IV DBT+DM decreased false positive results by 33%.Conclusion
Adding digital breast tomosynthesis to digital mammography improves the diagnostic accuracy in breast cancer screening. 相似文献17.
Purpose
To evaluate the interobserver agreement and the diagnostic performance of various qualitative features in shear-wave elastography (SWE) for breast masses.Materials and methods
A total of 153 breast lesions in 152 women who underwent B-mode ultrasound and SWE before biopsy were included. Qualitative analysis in SWE was performed using two different classifications: E values (Ecol; 6-point color score, Ehomo; homogeneity score and Esha; shape score) and a four-color pattern classification. Two radiologists reviewed five data sets: B-mode ultrasound, SWE, and combination of both for E values and four-color pattern. The BI-RADS categories were assessed B-mode and combined sets. Interobserver agreement was assessed using weighted κ statistics. Areas under the receiver operating characteristic curve (AUC), sensitivity, and specificity were analyzed.Results
Interobserver agreement was substantial for Ecol (κ = 0.79), Ehomo (κ = 0.77) and four-color pattern (κ = 0.64), and moderate for Esha (κ = 0.56). Better-performing qualitative features were Ecol and four-color pattern (AUCs, 0.932 and 0.925) compared with Ehomo and Esha (AUCs, 0.857 and 0.864; P < 0.05). The diagnostic performance of B-mode ultrasound (AUC, 0.950) was not significantly different from combined sets with E value and with four color pattern (AUCs, 0.962 and 0.954). When all qualitative values were negative, leading to downgrade the BI-RADS category, the specificity increased significantly from 16.5% to 56.1% (E value) and 57.0% (four-color pattern) (P < 0.001) without improvement in sensitivity.Conclusion
The qualitative SWE features were highly reproducible and showed good diagnostic performance in suspicious breast masses. Adding qualitative SWE to B-mode ultrasound increased specificity in decision making for biopsy recommendation. 相似文献18.
Youstina G.S. Ebrahim Mariam R. Louis Engy A. Ali 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(4):1175-1181
Objectives
Comparing the diagnostic accuracy of different MRI techniques in characterization of breast lesions.Methods
The study was performed using 1.5T MRI and included 35 females with detected 47 breast lesions. Lesions were analyzed regarding their morphology, kinetic curve pattern, DWI and tCho peak measurement. The results of each MRI parameter were correlated to histo-pathology.Results
The study included 35 females with 47 breast lesions. Sensitivity and specificity were 87.5% and 93.3% using morphology alone. By using curve pattern, they were 96.9% and 73.3%. DWI was 96.9% sensitive, 66.7% specific, and MRS was 74.2% sensitive and 71.4% specific. The cut-off ADC value was 1.063?×?10?3?mm2/s. Choline cut-off value was (0.36?mmol/l). Sensitivity and specificity were increased to 100% and 93.3% after combining either kinetic curve or DWI with morphology. Sensitivity was increased to 90.3%, after combining MRS with morphology, however this slightly reduced the specificity to 92.9%.Conclusion
MRI is very sensitive for detection of breast lesions, however it lacks specificity. Post-processing tools and functional MRI have improved the specificity. MRS has increased the sensitivity, however specificity has been slightly decreased.Advances in knowledge
Functional MRI is very helpful for characterization of different breast lesions, thus avoiding unnecessary intervention. 相似文献19.
Objective
To compare the diagnostic performances of strain elastography (SE) and shear-wave elastography (SWE) for predicting response to neoadjuvant chemotherapy (NACT) in patients with breast cancer.Methods
This prospective study recruited 71 eligible patients from June 2014 to May 2016. All patients provided written informed consent. Tumour stiffness was assessed by the SE strain ratio (R), SWE maximum elasticity (Emax) and SWE mean elasticity (Emean). Ultrasonic elastography (UE) assessments were performed at each NACT cycle (t1???t6). For the purpose of predicting, the relative changes in elastographic parameters after the first and second NACT cycles were considered as the variables [Δ(t1) and Δ(t2)]. The area under the receiver operating characteristics (AUC) curve was compared.Results
ΔEmean(t2) and R2 displayed the best diagnostic performances within their own modalities (AUC?=?0.93 and 0.90 for predicting favourable response to NACT; AUC?=?0.92 and 0.78 for predicting NACT resistance, respectively). There were no significant differences in AUCs for ΔEmean(t2) and some UE parameters (P?>?0.05). By contrast, ΔEmean(t2) was significantly superior to all other SE parameters for predicting resistance (P?<?0.05).Conclusions
SE and SWE exhibited similar performances for predicting favourable NACT responses; SWE was better than SE for predicting NACT resistance.Key Points
? Elastography parameters after the second NACT cycle showed the best diagnostic performances. ? SWE and SE yielded similar diagnostic performances in predicting favourable responses. ? SWE performed better than SE in predicting the pathological resistance to NACT. ? Discrepant results may be due to the breast thickness and lesion depth.20.
Hye Shin Ahn Jong Beum Lee Mirinae Seo Sung Hee Park Byung Ihn Choi 《La Radiologia medica》2018,123(4):260-270