前牙漂移正畸治疗后烤瓷联冠牙周夹板的临床应用

目的观察牙周病患者前牙漂移行牙周、正畸联合治疗后,用烤瓷联冠牙周夹板固定后的临床治疗效果。方法选择16例前牙漂移患者在进行牙周、正畸联合治疗后运用烤瓷修复技术,将发生漂移的前牙与近、远中1～2个邻牙做牙齿制备。取模制作烤瓷联冠,作为牙周夹板。结果 16例前牙漂移患者行牙周、正畸联合治疗后,采用烤瓷联冠牙周夹板固定,取得了满意效果。修复后随访至24个月,修复体美观、舒适、异物感小,对说话和进食无影响,患者均表示满意。结论运用烤瓷联冠作为前牙漂移正畸后的牙周夹板,不失为一种行之有效的方法。     

正畸联合固定保持治疗牙周病伴有前牙移位11例效果分析

目的：回顾分析对伴有前牙扇形移位的牙周病患者行正畸联合固定保持治疗的效果。方法选择因牙周病致前牙扇形漂移就诊的中老年患者11例,经牙周维护治疗及正畸牙列复位后选用烤瓷联冠或舌侧保持丝保持,观察患者前牙美观、咬合及牙周情况改善情况。结果通过正畸及固定保持治疗,纠正了牙周病前牙倾斜移位,改善了美观,调整了咬合关系,巩固了牙周治疗的效果。结论正畸联合固定保持治疗牙周病前牙漂移能有效改善美观和咬合功能,有利于牙周组织健康的修复。     

金属烤瓷联冠固定老年人松动牙的临床体会

目的对老年人松动牙齿运用金属烤瓷联冠进行固定,观察其临床效果。方法利用患牙两侧健康牙齿做基牙,制作金属烤瓷联冠形成牙周夹板,分散颌力,减轻单个牙齿牙周组织的负荷。结果33例修复体通过3年、4年随访结果成功率分别为96.8%、87.5%。结论选择适应症,对老年人松动牙齿运用金属烤瓷联冠进行固定修复可取得满意的临床效果。     

前牙松动的固定治疗

目的 探讨松动前牙的固定及正常咬合功能的恢复。方法 笔者对35例患者152颗松动前牙采用牙周夹板固定和烤瓷联冠固定，其中前下牙松动伴牙列不齐的老年患者采用牙周夹板固定，上下前牙松动牙列整齐的中老年患者采用烤瓷联冠固定。并经过半年至6年临床疗效观察。结果 35例患者前牙固定良好无松动，能行使正常咬合功能。其中2例牙周夹板固定患者曾因咀嚼硬物致牙周夹板断裂而重新固定。结论 前牙松动固定的临床效果满意。但牙周夹板固定治疗是非永久性固定治疗，临床上掌握适应症。     

牙周病前牙漂移正畸治疗及铸造夹板保持的研究

目的：探讨牙周病导致前牙漂移患者正畸治疗后的保持效果。方法：对30例前牙漂移的牙周病患者采取正畸及牙周联合治疗后进行前牙铸造夹板固定,半年后随访其保持效果进行研究。结果：30例患者的错胎畸形得到矫正矫治,结束时牙周情况较矫治前明显改善,前牙铸造夹板保持效果良好。结论：口腔正畸治疗可改善患者的牙周情况,铸造夹板保持可维持牙周健康。     

采用固定正畸技术联合前牙烤瓷修复的临床疗效分析

目的分析探究固定正畸技术联合前牙烤瓷修复应用于成人前牙美容的的临床疗效。方法对31例患者给予固定正畸技术联合前牙烤瓷修复治疗,经过两年随访复诊,对修复体协调性、牙齿移位、语言和咀嚼功能、牙周健康等各种情况进行临床效果分析评价。结果本组31例固定正畸技术联合前牙烤瓷修复治疗患者中,有1例患者3颗牙齿在6个月内出现微小移位,经相应处理后该患者在之后复诊过程中牙齿移位情况没有再出现。其余患者在修复后6个月、9个月和之后的2年内的复查中,未出现牙齿移位、松动情况,牙龈形、色、质健康,无炎症出现,语言和咀嚼功能恢复良好。结论对于牙齿美容患者,固定正畸技术联合前牙烤瓷修复术克服了单一治疗方法的局限性,达到美观、功能二者相统一的效果。临床修复治疗效果良好,值得广泛推广和应用。     

中、重度牙周炎的联冠修复治疗

目的观察联冠治疗中、重度牙周病的临床效果。方法选取我科中、重度牙周炎患者10例,患牙经过完善的牙周基础治疗后行烤瓷联冠固定。结果牙周病患牙齿行烤瓷联冠修复后固定效果良好,患者咀嚼功能改善。结论联冠修复治疗中、重度牙周病是一种有效的治疗方法。     

固定矫正配合前牙金属烤瓷冠桥修复

目的 通过固定矫正位置异常的牙齿,配合前牙金属烤瓷冠桥修复,矫正无法解决的颜色或形状异常的前牙,使其获得美容、美齿、美观等美学的目的 .方法 选择18周岁以后美观要求较高的患者,经方丝弓或直丝弓矫治技术配合前牙烤瓷冠桥修复.结果 随着固定矫治和前牙烤瓷冠桥的联合应用,118例患者,随访4-9年绝大部分患者基牙均未见龈炎、牙周炎症等异常情况.仅有2例固定矫正配合前牙金属烤瓷冠桥修复患者使用不当有瓷脱落的情况. 结论固定矫治和前牙烤瓷冠桥联合应用效果理想.     

严重前牙牙体缺损的临床处理

目的 分析总结对严重前牙牙体缺损实施牙周手术、正畸牵引的方法来进行铸造桩核加烤瓷冠修复的病例.方法 对46列前牙牙体严重缺损的病例进行牙冠延长术、正畸牵引等方法治疗后进行铸造核桩加烤瓷冠修复.通过随访,对这些病例的临床效果进行分析比较.结果 经过1～4年的跟踪随访,发现严重前牙牙体缺损后经牙周和正畸方法处理后加桩冠修复,修复固位良好,牙周无明显红肿.X线片下,不见根尖及牙槽骨有明显改变.结论 通过实施牙周及正畸方法处理后行铸造核桩加烤瓷冠修复,临床效果较好.     

金属烤瓷联冠与粘接式牙周夹板固定早期牙周病松动牙的临床运用

目的 探讨金属烤瓷联冠与树脂粘接式牙周夹板固定松动牙的临床疗效.方法 选择38例因牙周病松动牙做烤瓷联冠修复(A组),38例牙周病松动牙树脂粘接式牙周夹板修复(B组),对治疗效果进行比较.结果 6年的随访疗效A组显著优于B组.结论 烤瓷金属联冠比粘接式牙周夹板能更好的改善松动牙受力的情况,达到治疗牙周病的目的.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.