TSH－IRMA──诊断甲亢的一种敏感特异性指标

对１２１例甲亢患者和１１０例正常人的促甲状腺激素（ＴＳＨ）用免疫放射法测定技术（ＩＲＭＡ）测定并进行对照性研究，发现甲亢组的ＴＳＨ－ＩＲＭＡ范围和平均浓度显著地低于正常对照组，二者之间有高度的显著性差异（Ｕ＝１３．６８，Ｐ＜０．０１）。根据ＴＳＨ－ＩＲＭＡ＜０．０３ｍＩＵ／Ｌ诊断甲亢的正确率为９３．４％。结果表明：ＴＳＨ－ＩＲＭＡ是一种高度敏感、高度特异性的方法，可以鉴别甲亢和甲状腺功能正常的人。     

A New System for Rapid Measurement of ATP

TheATPthatplaysanimportantrole'inbiologicalactivityofcells,whichisnotnonlytheenergysourceoflifebutalsoakindofregulatingagentofmanybioactivesubstances.So,itisofgreatimportancetomeasureATPrapidlyandpreciselyinthefieldsofbasicmedicine,clinicalmedicine,andpreventivemedicine.Presently,thebestmethodformeasuringATPisblolumlnescentanalysis['].Themethodistomeasureluminousintensityafterinjectionluciferase.Itneedsavastamountofexpensiveluciferase[2'3.4J.Theinstrumentiscomplex,oflargesizeandexpensive.…     

Exploration of IRES Elements within the ORF of the Coxsackievirus B3 Genome

Objective This study aimed to identify internal ribosome entry sites(IRESs) in the open reading frame(ORF) of the Coxsackievirus B3(CVB3) genome.Methods The sequences of P1, P2, or P3 of the CVB3 genome or the truncated sequences from each antithymocyte globulin(ATG) to the end of the P1, P2, or P3 gene were inserted into the pEGFP-N1vector. After transfection, possible IRES-dependent green fluorescent protein(GFP)-fused proteins were detected by anti-GFP western blotting. The sequences of possi...     

An Abduction－Traction Frame for the Treatment of Intertrochanteric Fracture of Femur

ＡｎＡｂｄｕｃｔｉｏｎ－ＴｒａｃｔｉｏｎＦｒａｍｅｆｏｒｔｈｅＴｒｅａｔｍｅｎｔｏｆＩｎｔｅｒｔｒｏｃｈａｎｔｅｒｉｃＦｒａｃｔｕｒｅｏｆＦｅｍｕｒＹＡＮＧＳｈｕ－ｈｕａ（杨述华）；ＤＵＪｉｎｇ－ｙｕａｎ（杜靖远）；ＺＨＵＴｏｎｇ－ｂａｉ（朱通伯）（...     

Imaging Techniques of Electrical Impedance Tomography for Real-time Medical Monitoring

Electrical Impedance Tomography （EIT） is a new functional imaging technique. To monitor the development of the internal hemorrhage which can not be continuously detected by presented clinical imaging methods, the imaging techniques of EIT are proposed for the continuous monitoring. The individual image mapping technique and consecutive images displaying technique were both used. Internal bleeding within human body was simulated by the drinking of 0.3% saline water and was measured continuously by EIT over a long period of time. A sequence of EIT images were generated at a rate of one image per second. It was found that the variations of the amounts of the saline water drunk could be shown by the consecutive images of EIT. Therefore, the imaging techniques are useful to facilitate EIT to become a promising bedside monitoring tool for the patients suffering from the active ongoing bleeding.     

Replacement of Helium by Argon for Measurement of Carbon Monoxide Diffusing Capacity of lung

Diffusion capacity for carbon monoxideof the lung (D_LCO_(SB)) of 118 normal subjectsand 48 patients was measured by using threedifferent gas mixtures respectively: (a) 10％He, 0.3％CO, 21％O_2 and the remainder N_2,(b)10％ Ar, 0.3％CO, 21％O_2 and the remain-der N_2; (C) 10％ He, 10％ Ar, 0.3％ CO, 21％O_2 and the remainder N_2. The results wereextremely close with each other (r= 0.99, P<0.0005). The date also showed that the concentra-     

Localization of Auricular Projection Area of the Liver and Its Use in the Monitoring of Viral Hepatitis

There is a connection between the health state of specific internal organs and the electrical characteristics of related skin areas, although sometimes remote. These skin areas are referred to as organ projection areas (OPA) and include acupuncture points…     

The Diagnostic Value of Radiographic Measurement of the Metacarpal to Senile Osteoporosis

ＴｈｅＤｉａｇｎｏｓｔｉｃＶａｌｕｅｏｆＲａｄｉｏｇｒａｐｈｉｃＭｅａｓｕｒｅｍｅｎｔｏｆｔｈｅＭｅｔａｃａｒｐａｌｔｏＳｅｎｉｌｅＯｓｔｅｏｐｏｒｏｓｉｓＤａｉＬｉｙａｎｇ；（戴力扬），ＣｈｅｎＤｅｙｕ；（陈德玉）ＷｕＤｅｓｈｅｎｇ；（吴德升）ａｎ...     

334例TSH－IRMA异常者T_3、T_4与FT_3、FT_4测定的对比研究

筛选３３４例ＴＳＨ免疫放射测定（ＴＳＨ－ＩＲＭＡ）异常者，其中甲亢２５０例，甲减８４例。并用放免法测定Ｔ３、Ｔ４与ＦＴ３、ＦＴ４水平。结果：①甲亢患者中３２．０％Ｔ３、Ｔ４、ＦＴ３、ＦＴ４正常；１１．２％仅ＦＴ３或／和ＦＴ４升高；２．０％只有Ｔ３或／和Ｔ４增高。②甲减患者中２６．２％Ｔ３、Ｔ４、ＦＴ３、ＦＴ４正常；２７４％ＦＴ３或／和ＦＴ４下降；７．１％只有Ｔ３或／和Ｔ４减低。提示联合测定ＴＳＨ－ＩＲＭＡ与ＦＴ３、ＦＴ４是了解甲状腺功能状态的首选方法；ＴＳＨ－ＩＲＭＡ宜在治疗后６～８周复查。     

A Preliminary Study of C-reactive Protein in the Diagnosis and Monitoring of Lyme Disease

Lymediseaseisatickborne,immune-mediated,inflammatorydisordercausedbythespirochete,Borreliaburgdorferi.Theinfectioncanproduceawidespectrumofclinicalmanifestationsthatcanbeconfusedwithmanyotherdiseaseentities.Clinicaldifferentiationisoftencomplexandconsequentlylaboratoriesareheavllyreliedontoprovidediagnosticevidence(Steereetal.,l977a,l977b,Steereetal.,l983a).CultureofBorreliablIrgdor/eri,thoughnotimP()ssible,israrelysuccessful,andtheseaIChfOrnonspecificlaboratoryabnormalitieswithdiagnosticv…     

Accuracy and Consistency of Respiratory Inductive Plethysmography for Overnight Tidal Volume Measurement

Breathing patterns,i.e.the time,volume andflow components of ventilation,may be recordedfrom inductive plethysmographic transducers placedaround the ribcage and abdomen.Respiratory induc-tive plethysmography ( RIP) is well suited for thestudy of breathing disturbances during sleep,since,unlike other techniques that require instrumentationof the airway,it disturbs neither ventilation norsleep.RIP has been used in recentyears for qualitativemonitoring of chestwallmotion during sleep.In par-tic…     

Preliminary Exploration of the Relationship between Apoptosisand Gastric Carcinoma and Its Precancerosis

Apoptosisisaphenomenoncommonlyseeninspecificdevelopingstageofphylogenesisinmanyanimals,andisoftenrelatedtotheshapeoforgan,maintenence,growthanddegenerationoftissues.Inrecentyears,owingtothefindingofitscloserelationtooncogenesis,studyingapoptosisbecomesthefocusincytobiologicresearch.Thisarticleexplorestherelationshipbetweenapoptosisandgastriccar.cinomaanditsprecancerosis,aswellasthepossibletherapeuticmechanismoftraditionalChinesemedicine.MORPHOLOGICCHARACERISTICSOFAPOPTOSISConfus…     

Measurement of mouse liver glutathione S-transferase activity by the integrated method

Objective: The integrated method was investigated to measure Vm/Km of mouse liver glutathione S-transfer-ase (GST) activity on GSH and 7-Cl-4-nitrobenzofurazozan. Methods: Presetting concentration of one substrate twenty-fold above the other's and taking maximum product absorbance Am as parameter while Km as constant, Vm/Km was obtained by nonlinear fitting of GST reaction curve to the integrated Michaelis-Menten equation In [Am/(Am -Ai)] + Ai/ ( ξ× Km ) = ( Vm/Km )×ti (1). Results: Vm/Km for GST showed slight dependence on initial substrate concentration and data range, but it was resistant to background absorbance, error in reaction origin and small deviation in presetting Km. Vm/Km was proportional to the amount of GST with upper limit higher than that by initial rate. There was close correlation between Vm/Km and initial rate of the same GST. Consistent results were obtained by this integrated method and classical initial rate method for the measurement of mouse liver GST. Conclusion: With the co     

Application Research of ＂3＋1＂ Mode for Birth Defects Monitoring

Objective To explore the ＂3＋1＂ monitoring mode for birth defects and quality control measures based on the population, and to obtain the related information data for birth defects.
Methods With the community population as the basis, adopting the unified monitoring scheme dominant by the leadership and administration of government, with districts （counties） as the monitoring sites, the ＂3＋1 ＂ monitoring mode for birth defects was based on a complete monitoring team with the combination of villages/residents＇ committees, townships （towns）, counties （districts） and the municipality. Demonstration research was carried out in the pilot districts/counties in Chongqing City.
Results Birth defects population monitoring system based on population and family planning management and service network was established, and during 2005 and 2006.application research was carried out for the monitoring methods among birth defects population in the pilot districts （counties）, obtaining the relevant information in regional birth defects, with a monitoring coverage of over 99%.
Conclusion Fully utilizing the birth management functions of Population and Famlty Planning System and the advantages of service networks, long term, dynamic birth defects monitoring system based on community population was established, with the integration of birth defects monitoring and regular reproductive health services, obtaining overall birth defects occurrence information in details, providing scientific basis for the government to formulate scientific, practical, economic and effective birth defects intervention policy, so as to improve the quality of the population.     

Clinical Study of Ambulatory Blood Pressure Monitoring Applied to The Evaluation of Acupuncture Treatment for Hypertension

Throughthestudyandapplicationof24hambulatorybloodpressuremonitoring(ABPM)itisfoundthatitreflectsthereallevelofhumanbloodpressurebetterthancasualmeasurementofbloodpressure(CBP)(1),ABPMhasbecomeaneffectivemeasuretoevaluateanti-hypertensiontreatments.InthisstudythetechniqueofABPMwasusedtoobservetheblood-pressure-loweringeffectofacupuncturetreatmentinpatientswithhypertension.METHODSClinicalDataAccordingtothecriteriafordiagnosinghypertensionanddecidingthestagesofhypertensionworkedoutbyWHO…     

Appleby operation for carcinoma of the body and tail of the pancreas

Objective To investigate the influence of glucose deprivation on the formation of multidrug resistance of hepatocellular carcinoma and to clarify its mechanism. Methods HepG2 cells were exposed to glucose-free DMEM medium for 24,48 and 72 h respectively. Apoptotic index of the HepG2 cells exposed to low glucose was analyzed by Annexin/P Ⅰ method using flow cytometry after administration of 5-Fu.     

Study for the Mechanisms of Acupuncture Analgesia

ＳｔｕｄｙｆｏｒｔｈｅＭｅｃｈａｎｉｓｍｓｏｆＡｃｕｐｕｎｃｔｕｒｅＡｎａｌｇｅｓｉａＨａｎＪｉ－ｓｈｅｎｇ（韩济生）；（ＮｅｕｒｏｓｃｉｅｎｃｅＲｅｓｅａｒｃｈＣｅｎｔｅｒ．ＢｅｉｊｉｎｇＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ．Ｂｅｉｊｉｎｇ）（１００...