核素脑池显像诊断和定位脑脊液鼻漏的相关技术环节及临床价值

目的：探讨核素脑池显像诊断和定位脑脊液鼻漏的临床价值及提高定性和定位诊断的有关技术环节。方法：采用^99Tc^m-DTPA法对12例脑脊液鼻漏患者进行核素脑池显像。结果：11例颅底至鼻部有异常放射性浓聚影，其中9例手术证实漏口与核素脑池显像定位诊断完全一致，其诊断灵敏度和定位准确率分别为91．7％（11／12）和81．8％（9／11）。结论：^99Tc^m-DTPA脑池显像作为灵敏、简便和定位准确的检查手段，可用于诊断和定位脑脊液鼻漏。提高定性和定位诊断的技术环节包括：显像体位、图像标志、显像时机、促使脑脊液鼻漏和鼻道棉拭放射性测定。     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

目的探讨HawkeyeSPECT仪融合图像对脑脊液鼻漏诊断和定位的临床价值。方法选择33例确诊脑脊液鼻漏的患者,术前腰椎穿刺注射^99Tc^m-DTPA后120和180min行脑池平面显像,然后分别在同一床位进行SPECT和CT扫描,扫描结束后,进行图像处理及图像融合,通过图像分析确定脑脊液鼻漏的漏口、漏道,并做对比分析。采用SAS6．12软件进行统计学处理,对平面和融合显像的2组数据比较行x^2检验。结果33例患者中,融合显像31例、平面显像30例颅底至鼻部有异常放射性浓聚影,其中融合显像有30例、平面显像有18例与手术证实漏口完全一致,其诊断灵敏度和定位准确性分别为93．9％（31／33）,90．9％（30／33）和93．5％（29／31）,78．3％（18／23）。2种方法的诊断灵敏度差异无统计学意义（x^2=0．65,P〉0．05）,定位准确性差异有统计学意义（x^2=10．30,P〈0．05）。结论^99Tc^m-DTPA脑池SPECT显像与同机定位CT图像融合作为灵敏、简便和定位准确的检查手段,可用于诊断和定位脑脊液鼻漏的漏口、漏道。     

99mTc-DX淋巴显像诊断肢体淋巴水肿的初步应用

目的：探讨淋巴显像对肢体淋巴水肿的诊断价值。材料和方法：61例病人行^99mTc-右旋糖酐（DX）全身显像。结果：将显像图分为正常、侧支回流、混合回流、皮肤回流和无回流等5种类型。在74个水肿肢体中，67个显示各种回流障碍，还发现5个无水肿肢体有淋巴回流异常。4例混合型和1例无回流型病人行淋巴管-静脉吻合术后痊愈，1例皮肤回流型计划行吻合术，但术中未找到有功能的淋巴管而改行局部病变组织切除术。结论：淋巴显像诊断淋巴水肿的灵敏度高，可显示肢体淋巴链结构和淋巴回流障碍等信息，对治疗方法选择有很大价值，但需注意质量控制。     

脑脊液鼻漏的CT扫描技术

脑脊液鼻漏的ＣＴ扫描技术李小光，范焱，曲来泽脑脊液鼻漏是指脑脊液经异常通道流入副鼻窦、鼻腔形成的漏。脑脊液鼻漏通常由外伤，肿瘤术后以及肿瘤破坏等原因所致。它给患者带来了很大的痛苦，ＣＴ扫描技术的好坏，对临床诊断和治疗起着重要的指导作用。一、资料与设备...     

脑脊液鼻漏的MR诊断价值

目的　探讨脑脊液鼻漏磁共振成像的诊断价值。方法　回顾性分析临床手术证实脑脊液鼻漏患者 16例 ,所有患者均行MR检查 (T2 WI、2DTSE水成像或 3DCISS脑室成像 )及鼻腔流出液糖定量分析。结果　脑脊液漏 14例位于筛窦 ,2例位于蝶窦。所有受检者仰卧位筛窦黏膜及其窦腔内在上均未见明显脑脊液信号 ;改变体位 (脑脊液流出位 )MR扫描 ,可见鼻窦或鼻腔内液体信号积聚。 16例患者中 2DTSE、3DCISS及T2 WI可见筛板、蝶鞍及其周围有线状液体信号向下延伸及筛窦和蝶窦。所有患者鼻腔漏出液葡萄糖定量分析 >3 0mg/L。结论　MR是诊断脑脊液鼻漏有效的方法。优化MR扫描序列和检查方法有利于漏口的显示     

用99Tcm-DTPA肾动态显像判断2型糖尿病肾小球功能

目的　探讨用99Tcm DTPA肾动态显像判断 2型糖尿病患者肾小球功能的临床价值。方法正常对照者 12例 ,2型糖尿病患者 5 1例 ,根据尿微量白蛋白测定结果分组 ,分别行99Tcm DTPA肾动态显像测定总肾与分肾肾小球滤过率 (GFR)。结果　① 2型糖尿病各组总肾及分肾GFR均低于对照组。②总肾及分肾GFR与尿微量白蛋白呈显著负相关 ,r分别为 - 0 4 5 7,- 0 4 12和 - 0 4 2 4 (P均 <0 0 1)。③ 5 1例 2型糖尿病患者中有 5例总肾GFR正常 ,而分肾GFR异常。结论　用99Tcm DTPA肾动态显像判断 2型糖尿病患者早期肾小球功能损害有一定价值。     

99Tc m-DTPA SPECT/CT显像对脑脊液漏的诊断价值

目的:探讨 99Tc m-二乙撑三胺五乙酸(DTPA)SPECT/CT显像对脑脊液漏(CSFL)的诊断效能及其临床应用价值。 方法:回顾性分析2018年4月至2020年1月间于上海交通大学附属第六人民医院行手术治疗的CSFL疑似患者23例[男11例,女12例,年龄(44.2±15.1)...     

脑脊液鼻漏的CT扫描技术

本文分析了１４例脑脊液鼻漏患者ＣＴ扫描的结果,比较了横断,俯卧冠状扫描和脑池造影扫描对脑脊液鼻漏诊断的价值,充分肯定了高分辨力ＣＴ冠状扫描是显示漏孔最有效和简便的方法,同时认为横断扫描对诊断有一定帮助应作为基础扫描,而脑池造影ＣＴ扫描准确性最高,应在冠状平扫后选用。     

脑脊液漏的诊断和治疗

目的 探讨脑脊液漏的规范化诊断和治疗方法以改善患者预后.方法 回顾性分析我院自1994年1月-2007年3月收治的75例脑脊液漏的病例资料,其中鼻漏51例,耳漏9例,切口或伤口漏15例;外伤性漏39例,手术后漏32例,自发性漏4例.23例通过体位休息和药物治疗治愈,16例通过脑脊液引流和(或)伤口局部处理获愈;手术治疗36例,其中开颅修补17例,颅外修补17例,分流5例(其中3例为修补术后再行分流).结果 治愈64例,好转10例,死亡1例.结论 规范化的诊断、治疗方案有助于提高脑脊液漏的治愈率,减少并发症.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.     

Hawkeye SPECT仪融合图像用于脑脊液鼻漏诊断和定位

Objective The purpose of this study was to evaluate the clinical value of the 99Tcm-DTPA cerebrospinal fluid (CSF) Hawkeye SPECT fusion imaging for diagnosing and localizing CSF rhinorrhea (CSFR). Methods Thirty-three patients with suspected CSFR were included in this study. All cases un-derwent planar and SPECT and CT imaging at 120 and 180 min, respectively, after 99Tcm-DTPA injection via lumbar puncture before surgery treatment. The location and path of CSF leakage were diagnosed on pla-nar and SPECT fusion imaging. SAS 6.12 software was used to analyze both sets of imaging data, and the χ2 test was used to compare the results from planar imaging with those of SPECT fusion imaging. Results In 33 patients with CSFR, 31 abnormally concentrated radionuclide activity and location of leakage were foun-ded on SPECT fusion imaging, whereas 30 of such abnormalities were detected by planar imaging. All CSFR cases were confirmed by surgery afterwards. The sensitivity and accuracy for diagnosing and localizing CSFR were 93.9% (31/33), 90.9% (30/33) in SPECT fusion imaging and 93.5% (29/31), 78.3% (18/23) in planar imaging. Conclusion 99Tcm-DTPA CSF Hawkeye SPECT fusion imaging is an efficient, simple and accurate method for diagnosing and localizing CSF leakage.