磷酸钙骨水门汀修复髓室底穿孔后渗漏的实验研究

目的 :寻求修复髓室底穿孔较好的修复材料。方法 :在离体牙上采用染料渗入法检测CPC、LGIC及CPC与LGLC夹层技术修复髓室底穿孔后的渗漏情况。结果 :三组穿孔修复材料的渗漏从小到大排列顺序为 :LGLC组、夹层技术组、CPC组 ,三组间渗漏无显著性差异 (P >0 .0 5 )。结论 :CPC具有良好的密封性能 ,其密封性与LGIC相近似。结合CPC的其它性能 ,认为CPC可作为髓室底穿孔较理想的修复材料之一。     

磷酸钙骨水泥修复髓室底穿孔渗漏的实验研究

目的 研究磷酸钙骨水泥（CPC）修复髓室底穿孔的渗漏。方法 在离体牙上采用染料渗入法检测CPC、光固化玻璃离子水门汀（LGIC）及夹层技术修复髓室底穿孔的渗漏情况。结果 三组穿孔修复体渗漏从小到大依次为：LGIC组、夹层技术、CPC组，三组渗漏差异无显著性（P＞0．05）。结论 CPC具有良好的密封性能，其密封性与LGIC相近似。CPC可作为髓室底穿孔较理想的修复材料。     

磷酸钙骨水泥修复髓室底穿孔的临床研究

目的 :研究CPC修复髓室底穿孔的临床效果。方法 :将 6 8颗髓室底穿孔患牙随机分为CPC组 (46颗 )和对照组 (2 2颗 ) ,均先行根管治疗 ,然后穿孔处分别采用CPC和氢氧化钙充填修复 ,并作永久性充填 ,所有治疗牙均随访观察 18～ 2 4月。结果 :CPC组成功 43颗 ,失败 3颗 ,其疗效明显优于对照组 (P <0 .0 5 ) ;医源性和龋源性穿孔之间 ,其疗效无显著性差异 (P >0 .0 5 )。结论 :CPC是修复髓室底穿孔较好的一种材料 ,其疗效与穿孔大小有关     

磷酸钙骨水泥修复髓室底穿孔的临床研究

目的：研究CPC修复髓室底穿孔的临床效果。方法：将68颗髓室底穿孔患牙随机分为CPC组（46颗）和对照组（22颗）,均先行根管治疗,然后穿孔处分别采用CPC和氢氧化钙充填修复,并作永久性充填,所有治疗牙均随访观察18－24月。结果：CPC组成功43颗,失败3颗,其疗效明显优于对照组（P＜0．05）;医源性和龋源性穿孔之间,其疗效无显著性差异（P＞0．05）。结论：CPC是修复髓室底穿孔较好的一种材料,其疗效与穿孔大小有关。     

屏障材料修复比格犬髓室底穿孔的组织病理学观察

目的:从组织病理学角度评价胶原基纳米羟基磷灰石骨修复材料(nano-hydroxyapatite/collagen composite,NHAC)作为屏障材料修复比格犬髓室底穿孔的效果.方法:3只成年比格犬的36个前磨牙建立髓室底穿孔模型后,随机分配到实验组和对照组,实验组先用NHAC形成髓室底屏障,再用光固化玻璃离子水门汀(LGIC)修复穿孔;对照组直接以LGIC修复穿孔.分别于术后1、4、12周取材并制作组织病理切片,光学显微镜下观察组织病理改变.结果:术后1周,两组均未见明显改变.术后4周,两组均以轻至中度炎症反应为主,其中实验组可见NHAC部分降解,纤维组织修复或新骨形成;对照组以纤维组织修复多见.术后12周,实验组中有4例可见NHAC大部分降解,并有纤维组织修复或新骨形成,2例上皮增生伴中度炎症反应;对照组中4例为纤维组织修复,2例上皮增生.结论:与LGIC直接修复相比,NHAC作为屏障材料可诱导骨组织形成,修复后炎症反应较轻.     

复方五倍子作为髓室底穿孔屏障材料的微渗漏研究

目的:探讨复方五倍子用作髓室底穿孔屏障材料对封闭性的影响.方法:在55个离体牙上制造髓室底穿孔模型后,分别用银汞合金(A组)、复合树脂(R组)、复方五倍子作屏障银汞合金修复(AM组)、复方五倍子作屏障复合树脂修复(RM组)及MTA(MTA组)修复,通过染料渗漏法测定各组渗漏情况.结果:阳性对照组(PC)为完全渗漏,阴性对照组(NC)无染料渗入.所有实验组均有不同程度的渗漏.微渗漏值由大到小依次为:A组、R组、AM组、MTA组、RM组,各组间两两比较,除AM组和R组、AM组和MTA组外,均有统计学差异(P＜0.05).AM组和RM组无超填.结论:复方五倍子作为屏障材料来修补髓室底穿孔可以减轻微渗漏,并能有效防止修复材料的超填.     

自固化磷酸钙治疗根尖周病的临床研究

目的　寻求有效的充填根管及修复髓室底穿孔的材料。方法　将需要治疗的 2 88颗患牙随机分为实验组 15 6颗 (其中 18颗见髓室底穿孔 ) ,对照组 132颗。实验组用自固化磷酸钙糊剂充填根管 ,对照组用传统的酚醛糊剂加牙胶尖充填根管。结果　实验组有效率 96 .79% ,对照组 89.39%。经统计学检验 ,两组差异有显著性 (P <0 .0 5 )。髓室底穿孔修复率 83.33%。结论　自固化磷酸钙能有效地控制感染 ,可用于充填感染根管并修复髓室底穿孔     

生物活性玻璃微粒修复髓室底穿孔的临床观察

目的观察生物活性玻璃微粒(Bioglass)修复髓室底穿孔的临床疗效.方法选择髓室底穿孔病例75例,患牙86个,随机分为两组,试验组采用生物活性玻璃微粒,对照组采用光固化玻璃离子修复.1年后观察临床效果.结果试验组成功率81.3%,进步13.9%,对照组成功率46.5%,进步23.3%,两组间有显著性差异(P<0.05).其疗效与穿孔直径密切相关,与穿孔原因关系不明显.结论生物活性玻璃微粒是一种良好的髓室底穿孔的修复材料.     

氢氧化钙碘仿糊剂修复髓室底穿孔的临床研究

目的 观察氢氧化钙碘仿糊剂修复髓室底穿孔的临床疗效。方法 选择髓室底穿孔的患者65例，患牙68颗，随机分为两组，试验组采用氢氧化钙碘仿糊荆修复髓室底穿孔，再用玻璃离子水门汀垫底，对照组直接采用玻璃离子水门汀修复穿孔。一年后复查，观察其治疗效果。结果 试验组成功率(76．19％)明显高于对照组，两组间有显著性差异，并且其疗效与穿孔原因及穿孔直径有密切关系。结论 氢氧化钙碘仿糊剂是一种良好的髓室底穿孔的修复材料。     

iRoot BP修复磨牙髓室底穿孔的研究

目的 探讨iRoot BP直接修复髓室底穿孔的效果。方法 收集新鲜拔除的人恒磨牙40颗,其中36颗于髓室底中央制备直径2 mm的穿孔洞型,随机分为A、B组,每组18颗,分别用iRoot BP和矿物三氧化聚合体（MTA）修复髓室底穿孔;另外4颗为对照组,只开髓不制备髓室底穿孔。从A、B组中各随机选择3个样本用扫描电子显微镜观察材料和牙本质的结合界面;其余15个样本用葡萄糖氧化酶-蒽酮法检测微渗漏值。结果 A组中,iRoot BP与牙本质结合较为紧密,而B组中MTA和牙本质之间存在不均匀的微小间隙。在观察期内,B组的微渗漏值高于A组,其差异有统计学意义（P<0.05）。结论 iRoot BP修复髓室底穿孔的封闭效果优于MTA。     

Light-cured glass ionomer cement as a retrograde root seal

A light-cured glass ionomer cement was investigated as a retrograde root seal, without a retrograde cavity. This was compared with the material used in a retrograde cavity, and with a conventional glass ionomer cement, as a seal. The adaptation and sealing ability of the test materials were assessed using a confocal optical microscope with a fluorescent dye. The root canals of 40 extracted human single-rooted teeth were prepared and filled with gutta-percha and sealer. All the teeth were subsequently apicected, then divided into four equal groups. In one group, a retrograde cavity was prepared, and the light-cured glass ionomer cement was placed as a retrograde root filling. No retrograde cavities were prepared in the three remaining groups. The light-cured glass ionomer cement was applied directly onto the apicected root face. Two different thicknesses of light-cured glass ionomer cement were tested, a thin layer (≈1 mm) in one group, and a thicker layer (<1 mm) in another group. A conventional glass ionomer cement was used in the last group, and applied directly onto the root face in a single thickness (≈1 mm). In the group where the light-cured glass ionomer cement was used in a retrograde cavity, the material was often well adapted to one cavity wall, but gaps were found on the opposite wall. The light-cured and conventional glass ionomer cement retrograde root seals were well adapted to the root face, regardless of the thickness of material used. The thinly applied (≈1 mm) light-cured glass ionomer cement retrograde root seals permitted the least leakage. This was significantly less than the light-cured glass ionomer cement used with a retrograde cavity (P > 0.001). The greatest extent of dye penetration was found with the thick (< 1 mm) light-cured and conventional glass ionomer cement (≈1 mm) root seals; the differences between these were not significant. The light-cured glass ionomer cement was only suitable as a retrograde root seal when a thin layer (≈1 mm) was used.     

三种髓室底穿孔修补材料的临床对比研究

目的：评价矿物三氧化物凝聚体（ MTA）、玻璃离子水门汀和银汞合金在修补髓室底穿孔的临床疗效。方法：将78颗髓室底穿孔的患牙,进行根管治疗后随机分为3组,分别应用MTA、玻璃离子水门汀和银汞合金修补髓室底,1年后复查观察其临床疗效。结果：MTA治疗组成功率92．3％,玻璃离子水门汀治疗组成功率69．2％,银汞合金治疗组成功率53．8％。经统计学处理,MTA组与其余两组之间差异有统计学意义（P＜0．05）。 MTA组的成功率高于玻璃离子组和银汞合金组。 MTA组成功率与穿孔原因有关,医源性穿孔治疗成功率高于龋源性穿孔,两者差异有统计学意义（P＜0．05）。结论：MTA具有良好的生物活性和组织相容性,临床疗效良好,应用于修补髓室底穿孔可以提高患牙的保留率。     

玻璃离子水门汀牙体充填后边缘封闭性的观察

目的：比较三种玻璃离子水门汀牙体充填修复后边缘封闭性的差别。方法：离体前磨牙80颗按要求制备洞型,随机分成4组,分别用三种玻璃离子水门汀（新世纪齿科材料有限公司玻璃离子水门汀I型、II型,日本GCFujiII）充填修复,另外一组用玻璃离子水门汀II型修复后再涂隔湿剂（凡士林）。经冷热交替试验（0℃～55℃,循环500次）,采用1%亚甲蓝染料渗入法观察充填体与牙体洞壁间边缘微渗漏的情况。结果：玻璃离子水门汀I型（普通型）边缘封闭性与其他各组存在显著差异（P〈0.01）;玻璃离子水门汀II型（树脂增强型）、GCFujiII与隔湿剂组边缘封闭性存在差异（P〈0.05）;玻璃离子水门汀II型与GCFujiII边缘封闭性比较不存在差异（P〉0.05）。结论：玻璃离子水门汀II型与GCFujiII边缘封闭效果相同;隔湿剂能降低微渗漏。     

The adaptation and sealing ability of light-cured glass ionomer retrograde root fillings

The adaptation and sealing ability of a light-cured glass ionomer cement when used as a retrograde root filling was assessed using a confocal optical microscope with and without a fluorescent dye. This material was compared with a conventional glass ionomer cement and amalgam. The root canals of 60 extracted human single-rooted teeth were prepared and filled with gutta-percha and sealer. All the teeth were apicected, retrograde cavities were prepared, and then divided into three groups of 20 teeth each and filled with the test materials. The light-cured glass ionomer cement was well adapted to the retrograde cavity and apicected root surface. Within the retrograde cavity the cement was often well adapted to one wall, but gaps were found on the opposite cavity wall. This was probably caused by the polymerization contraction of the material. In contrast, the amalgam retrograde root fillings were poorly adapted to the cavities, with gaps between the cavity walls and amalgam. This group exhibited the poorest sealing ability as measured by the extent of dye penetration. The conventional glass ionomer cement was often found smeared over the root face, and there were unfilled voids at the base of some retrograde cavities. The results of the dye leakage study were analysed statistically. The sealing ability of the light-cured glass ionomer cement was significantly better than that of amalgam (P less than 0.001). The dye penetration around the light-cured glass ionomer cement and the conventional glass ionomer cement was not significantly different (P greater than 0.05). However, the sealing ability of the conventional glass ionomer cement was significantly better than that of amalgam (P less than 0.05).     

A comparative scalability study of different retrofitting materials

The purpose of this study was to compare the sealing ability of high-copper amalgam, glass ionomer cement, and silver glass ionomer cement as retrofitting materials when used with and without varnish. Seventy extracted human single-rooted anterior teeth were instrumented and the root canals obturated with laterally condensed gutta-percha and sealer. The apical 3 mm of each root was resected and a 2 mm-deep apical Class I preparation cut. The roots were then randomly allocated to six groups of 10 teeth and retrofitled with one of die experiment materials. Group I comprised high-copper amalgam; group 2, high-copper amalgam with cavity varnish; group 3, glass ionomer cement without varnish: group 4, glass ionomer cement with varnish; group 5, silver glass ionomer cement without varnish; and group 6, silver glass ionomer cement with varnish. Two groups of five roots each were used as positive and negative controls. The root surfaces were coated with nail polish and specimens immersed in 2% methylene blue solution for 14 days. After vertical sectioning, dye penetration was examined under a stereomicroscope. The results of the study were analysed statistically. The sealing ability of the conventional glass ionomer cement with varnish was significantly better while dye penetration was higher in silver glass ionomer cement without varnish group than the other groups (P > 0.01).