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Persistent pain is not a normal part of aging. Nevertheless, many older patients have long-lasting, more or less medically unexplained pain symptoms and, consequently, are often severely disabled, incur high health care costs, and have high comorbidity rates. Moreover, the effects of early traumatization, especially due to wars, and even below the level of posttraumatic stress disorder (PTSD) are apparent. However, the developmental and neurobiological underpinnings of somatoform pain disorder, especially in pain-prone elderly patients, and its correlations with a history of war traumatization even decades after the incident remain unclear. Furthermore, a management strategy for this disorder tailored to older people and their special needs is lacking. Adequate therapeutic regimens such as adjusted psychotherapeutic procedures for elderly patients can only be promoted through a better understanding of the neurobiological and biographical underpinnings of this still controversial disorder.  相似文献   

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《Lancet》2003,361(9363):1065
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Fundamental ideas of the chaotic non-linear dynamical systems and their application in parasitology (e.g. Cephalomyvia populations, Trichomronas vaginalis invasions, Homo-Plasmodium systems) are discussed.  相似文献   

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Bamforth I 《Lancet》2002,359(9313):1260
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