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R Kobza E Oechslin R Prêtre D J Kurz R Jenni 《European journal of echocardiography》2003,4(3):223-225
Diverticula and aneurysms are rare congenital anomalies of the right atrium. Here, we report a case of a giant congenital diverticulum of the right atrium in a 27-year-old female and discuss the morphological characteristics distinguishing diverticula and aneurysms. 相似文献
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The cause of enlargement of the heart in infants and young children is still a fertile field for investigation. Only in recent years has it been demonstrated that in many cases what was formerly called “idiopathic hypertrophy” of the heart was in reality associated with congenital malformations, rheumatic fever, glycogen-storage disease, myocardial degeneration and fibrosis, etc. 相似文献
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Amyloid fibrils are formed when soluble proteins misfold into highly ordered insoluble fibrillar aggregates and affect various organs and tissues. The deposition of amyloid fibrils is the main hallmark of a group of disorders, called amyloidoses. Curiously, fibril deposition has been also recorded as a complication in a number of other pathological conditions, including well-known neurodegenerative or endocrine diseases. To date, amyloidoses are roughly classified, owing to their tremendous heterogeneity. In this work, we introduce AmyCo, a freely available collection of amyloidoses and clinical disorders related to amyloid deposition. AmyCo classifies 75 diseases associated with amyloid deposition into two distinct categories, namely 1) amyloidosis and 2) clinical conditions associated with amyloidosis. Each database entry is annotated with the major protein component (causative protein), other components of amyloid deposits and affected tissues or organs. Database entries are also supplemented with appropriate detailed annotation and are referenced to ICD-10, MeSH, OMIM, PubMed, AmyPro and UniProtKB databases. To our knowledge, AmyCo is the first attempt towards the creation of a complete and an up-to-date repository, containing information about amyloidoses and diseases related to amyloid deposition. The AmyCo web interface is available at http://bioinformatics.biol.uoa.gr/amyco. 相似文献
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A study of leukocyte antibodies is presented using (1) the sera of rabbits immunized with human leukocytes, and (2) the sera of three patients screened forthe presence of such antibodies from among 36 patients with hematologic disease,31 of whom (including the 3 studied in detail) had received multiple transfusions.The following technics are described and were employed: Leukoagglutination,leukoprecipitation including tube and agar-plate methods, agglutination ofantigen-coated tanned and untanned sheep erythrocytes, the effect of antiseraupon phagocytosis of heat-killed staphylococci by leukocytes, and upon ameboidmotility of leukocytes.The leukoagglutinin test gives reliable clearcut results providing that appropriate controls are included and certain criteria adhered to, in order to facilitatethe recognition of clumping due to other factors than true antigen-antibodyunion.No leukoprecipitins were detected in human sera with the technics used inthis study. Immune rabbit sera, on the other hand, gave two reaction-lines inagar media, when set up against leukocyte extract.Immune rabbit sera reacted strongly with antigen-coated tanned sheep redblood cells. Human sera did not so react. One of the three selected human serareacted with antigen-coated untanned erythrocytes, suggesting the presence of apolysaccharide antigen extractable from human leukocytes and capable of stimulating antibody formation in the human. Immune rabbit sera, and otherhuman sera, did not react in this test.A suggestive but perhaps not a conclusive effect upon phagocytosis of bacteriaby leukocytes exposed to human leukocyte antibody for 1 hour could be demonstrated.By means of ameboid motility studies, a cytotoxic effect of the human antiseraupon human leukocytes could be demonstrated after 18 hours of incubation, butnot after 3 hours. This was interpreted as evidence of a delayed reaction.Certain cardinal points from a clinical and theoretical standpoint with regardto the genesis of leukocyte antibodies in man are briefly reviewed. A possibleanalogy between leukocyte antibody formation and the homograft reaction isdiscussed. It is suggested that the rarity of leukocyte iso-antibody formationfollowing transfusion is related to the fact that the intravenous pathway may bea poor route of immunization for these antigens. Submitted on April 4, 1957 Accepted on July 1, 1957 相似文献
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标 题1.生存和心室肥大试验的基本原理、设计和基本特征 2.卡托普利对心肌梗死后左室功能不全患者病死率和患病率的影响:生存和心室肥大试验的结果 3.心肌梗死后2年的心血管死亡和左心室重构,基本的预报因子和长期应用卡托普利的结果:来源于生存和心室 肥大试验的资料作 者1.Moye LA,等 2.Pfeffer MA,等 3.St.John Srtton M,等 参考文献 1.Am J Cardiol,1991,68:70D~79D 2.N Engl J Mek,1992,327:669~677 3.Circulat… 相似文献
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