改良上睑提肌缩短术治疗中度和重度上睑下垂

目的 探讨应用改良上睑提肌缩短术治疗中、重度先天性上睑下垂的疗效.方法 对30例中、重度先天性上睑下垂患者(包括2例上睑下垂术后欠矫和复发患者),采用联合睑板切除的上睑提肌缩短术.术中睑板切除量根据睑板的宽度设计,上睑提肌切除量＝(上提量-睑板切除宽度)× (4～5) mm.并分离睑结膜和上睑提肌,切除一定量的睑结膜以防止结膜脱垂,对术后效果进行随访观察.结果 30例除3例矫正不足外,余均获得良好上提效果,上睑缘弧度自然,无严重并发症,仅少数患者早期有轻度睑裂闭合不全.结论 改良上睑提肌缩短术适用于中、重度先天性上睑下垂患者及上睑下垂术后欠矫的患者,在矫正畸形和改善外观方面均能达到良好的效果.掌握手术操作要点,有助于在功能和外形上取得满意效果.     

Treatment strategy for severe blepharoptosis

ObjectiveTo establish a treatment protocol for severe blepharoptosis. This protocol helps to achieve improved accuracy and more stable correction outcome.MethodsThe levator muscle function was evaluated pre-operation. When the levator function was less than 1 mm, the frontalis suspension technique was performed; when the levator function was more than 1 mm, the techniques of levator resection, combined excision of the tarsus and levator, and tarsus–levator–CFS suspension were performed sequentially until a satisfactory correction result was achieved.ResultsA total of 389 patients with severe ptosis (561 eyes) were included; 102 eyes received levator resection, 314 eyes received combined excision of the tarsus and levator, 53 eyes received tarsus–levator–CFS suspension, and 92 eyes received frontalis suspension. In total, a satisfactory correction result was achieved in 466 eyes, while 95 cases still presented with under-correction. The symmetry findings showed that 107 (27%) cases presented good symmetry, 203 (52%) cases presented moderate symmetry, and 79 (21%) showed poor symmetry.ConclusionThis new treatment protocol overcomes the drawbacks of the traditional strategy by standardizing the correction procedure, leading to improved accuracy and more stable correction results.     

Tarsal resection operation in correction of severe unilateral blepharoptosis with poor levator function

There are many options for surgical repair of congenital unilateral ptosis with poor levator function. We performed resection of tarsus, Müller muscle, and conjunctiva in conjunction with an intraoperative adjustable levator resection. Resection of tarsus, Müller muscle, and conjunctiva in conjunction with levator resection was performed in a prospective series of 17 consecutive patients with unilateral ptosis with poor levator function over a 2-year period. Pre- and postoperative upper eyelid margin to reflex distance, degree of levator function, amount of operative tarsus and Müller muscle resection, postoperative eyelid symmetry, and postoperative complications were evaluated. Mean preoperative upper eyelid margin to reflex distance was 0.11 mm. Mean postoperative upper eyelid margin to reflex distance was 3.20 mm. Improved postoperative eyelid symmetry within 1.0 and 1.5 mm was demonstrated in most of our cases (58% and 76%, respectively). The major complication has been exposure keratitis. Resection of tarsus, Müller muscle, and conjunctiva combined with adjustable levator resection can correct severe unilateral ptosis with poor levator function.     

不对称双侧先天性上睑下垂的分期手术治疗策略

目的 探讨不对称的先天性双侧上睑下垂进行分期手术的治疗策略。方法 对2011年至2013年的30例不对称双侧上睑下垂患者进行分期手术矫正。一期手术矫正较重侧(中~重度),行睑板部分切除联合上睑提肌缩短前徙术;3~6个月后再行较轻侧矫正,行睑板部分切除术或上睑提肌缩短术。术后随访3~24个月,术后评估内容包括矫正程度与双侧对称性。结果 全部30例患者60只眼,在矫正效果评估中,37(61.7%)只眼为充分矫正,23(38.3%)只眼为中等矫正,无矫正不足或过矫病例。对称性评估中,23(76.5%)例达到良好对称,7(23.5%)例达到中等对称,无对称不佳病例。结论 与我们以往的治疗经验相比,对于不对称的双侧先天性上睑下垂,分期手术治疗能够达到更好的对称效果。     

上睑提肌内限制韧带松解在治疗先天性上睑下垂中的意义

目的 在睑板上缘附近的上睑提肌内，有跨于内外眦角之间数条横向纤维束带即限制韧带，我们探讨其在治疗先天性上睑下垂中的意义。方法 将此韧带松解，可基本矫正大部分经度上睑下垂病例。若为轻，中度上睑下垂，且韧带松解后上睑仍有部分下垂，还需进行睑提肌腱膜折叠术。重度上睑下垂韧带松解后，还需进行眉区额肌筋膜瓣悬吊术。结果 本组27例随访3个月～1年，27例40只眼中38只眼轻、中、重度上睑下垂均矫正满意，2只眼良好，未见睑下垂复发。结论 松解上睑提肌内限制韧带，有助于恢复上睑提肌睑功能，易于矫正睑下垂且手术创伤小，形态自然，不易复发。     

Comparison of levator resection and frontalis muscle transfer in the treatment of severe blepharoptosis

BACKGROUND: The optimal surgical approach for blepharoptosis is dependent upon many factors, the most important being levator function. However, the preferred approach in severe blepharoptosis remains a matter of contention. METHODS: We investigated 130 patients with levator function between 2 and 4 mm who underwent corrective surgery for blepharoptosis between January 1990 and December 2004. There were 65 eyelids of levator resection performed in 50 patients and 105 eyelids of frontalis transfer performed in 80 patients. Postoperative results were evaluated, with an average follow-up period of 27 months. RESULTS: The average preoperative degree of ptosis was approximately 2.7 mm in cases treated with levator resection and 4.0 mm in cases treated with frontalis muscle transfer. The average postoperative level of ptosis was approximately 1.7 mm in levator resection and 2.1 mm in frontalis muscle transfer. The average degree of postoperative ptosis improvement was approximately 1.0 mm in levator resection and approximately 1.86 mm in frontalis muscle transfer. The most frequent complication of levator resection was undercorrection. Eyelid deformity due to excessive traction was more frequent in the frontalis muscle flap technique. CONCLUSION: Levator resection and frontalis transfer can effectively treat blepharoptosis patients with poor levator function. Frontalis muscle transfer should be performed more carefully in operation to avoid complications which too excessive contraction could cause for blepharoptosis patients with 2 approximately 4 mm of levator function. Also, some accessorial methods were regarded as necessary to prevent undercorrection in performing levator resection.     

Super-maximum levator resection for severe unilateral congenital blepharoptosis

The treatment for severe unilateral blepharoptosis is controversial. Sixteen consecutive cases of severe unilateral blepharoptosis were studied: eight had a super-maximum levator muscle resection (30 mm or more) and eight had a bilateral brow suspension with excision of the normal levator. Cosmetically acceptable results were achieved in six of eight cases undergoing a super maximum levator resection. Disparity in the palpebral fissure in downgaze ranged from 3 to 6 mm and was not bothersome to either patient or parent. Postoperative complications such as hypotropia and conjunctival prolapse can be minimized with careful technique. Four to eight cases undergoing bilateral brow suspension with excision of the normal levator had residual ptosis. Brow scars were occasionally noticeable. Overall cosmesis was considered better in the super-maximum levator resection group compared to the frontalis sling group by unbiased observers. Super-maximum levator resection is a good alternative in the treatment of severe unilateral blepharoptosis for selected cases, particularly for those who fear manipulation of the normal eyelid.     

Etiology and pathogenesis of aponeurotic blepharoptosis

How and why aponeurotic blepharoptosis develops was investigated in terms of the relationship between the levator aponeurosis and Mueller's muscle functioning as the muscle spindle of the levator muscle. A total of 200 consecutive patients with moderate to severe acquired blepharoptosis completed questionnaires regarding their history of physical irritations to the eyelids, and intraoperative conditions of the levator aponeurosis and Mueller's muscle were evaluated. Several kinds of physical irritations to the eyelids were reported, such as habitual rubbing of the eyelids, contact lens usage, cataract surgery, and continuous rubbing of the eyelids while crying all night. The two main findings for aponeurosis were that it was disinserted from the tarsus, resulting in a large amount of play between the aponeurosis and the tarsus, and that the aponeurosis and Mueller's muscle were attenuated and elongated. The authors believe that rubbing may have caused disinsertion as well as attenuation and elongation of the aponeurosis, which result in transmission failures between the levator muscle and the tarsus as well as between the levator muscle and the mechanoreceptor of Mueller's muscle, leading to clinical blepharoptosis.     

翼状韧带悬吊矫正先天性重度上睑下垂

目的 探讨翼状韧带悬吊矫正重度先天性上睑下垂的临床效果.方法 2010年1～11月,应用翼状韧带悬吊法治疗先天性重度上睑下垂患者15例15只眼,按照切开重睑术术式,打开眶隔,在距睑板上缘5 mm处剪断上睑提肌腱膜进入到上睑提肌下层,向结膜上穹窿分离,在上直肌前1/3和上睑提肌之间找到翼状韧带,用3-0丝线同上睑提肌缝合于睑板上缘,悬吊矫正上睑下垂,缝合形成重睑.结果 经过3～11个月随访,15只眼矫正良好,眼裂均在15～30 d基本闭合,无其他并发症发生,重睑弧度形态自然,外观满意.结论 翼状韧带悬吊治疗重度先天性上睑下垂疗效可靠,用翼状韧带代替上睑提肌,生理运动方向一致,术后眼睑外形动态与静态均较自然.

Abstract：

Objective To evaluate the clinical result of check ligament suspension for correction of congenital severe blepharoptosis. Methods Since Jan. 2010 to Nov. 2010, 15 eyes in 15 cases with congenital severe blepharoptosis were treated with the check ligament suspension. Palpebralis aponeurosis was exposured by opening fascia palpebralis during blepharoplasty. Palpebralis aponeurosis was cut off about 5 mm above the tarsus. The check ligament was seen in the intermuscular space between the segment of levator and the anterior one third of superior rectus attached to the conjunctival fornix. Congenital blepharoptosis could be corrected by suturing the check ligament and levator palpebrae superior to the upper margin of tarsal plate with 3-0 silk thread. Double eyelid plasty was carried out in the end. Results The follow-up period was 3-11 months with good cosmetic result. All the cases could close their eyes in 15 to 30 days with no complication. Conclusions In conclusion, this technique is quite successful in raising the level of the upper eyelid in severe congenital blepharoptosis. The check ligament moves in a similar direction as the natural movement of levator muscle, so both the postoperative static and dynamic appearance of the upper lid is more natural.     

Strategies for Simultaneous Double Eyelid Blepharoplasty in Asian Patients With Congenital Blepharoptosis

Background Most patients with blepharoptosis prefer to undergo a double eyelid operation and a ptosis repair simultaneously to achieve the optimal cosmetic and functional result. However, it is difficult to achieve symmetry in patients with blepharoptosis. Methods Surgery was performed on the levator aponeurosis or frontalis muscle to correct blepharoptosis while double eyelid surgery was simultaneously performed to correct blephroptosis in 264 patients over the past 15 years. This report describes 39 representative cases of unilateral congenital blepharoptosis and 30 representative cases of bilateral congenital blepharoptosis. In cases of unilateral ptosis with good or fair levator function, a levator resection or plication was performed, and the position of the lid margin was adjusted to 1 to 2 mm below the upper limbus. Cases of severe unilateral blepharoptosis were corrected by frontalis muscle flap, orbicularis oculi muscle flap, or frontalis myofacial flap, and the height of the double eyelid was created to be 1 to 2 mm less than the height on the normal side. The position of the lid margin was adjusted to the level of the superior limbus, and the height of the lid crease of the ptotic eye was determined to be according to that on the nonptotic side. For bilateral ptosis patients with equal levator function, the height of the double eyelid was designed symmetrically. Bilateral blepharoptosis patients with unequal levator muscle function should have the double eyelids on both sides created the same as in normal cases, and they must be grafted in proportion to the severity of the blepharoptosis. If the results are unpredictable, the two-stage operation should be performed. Results Only 30% of the eyelids in this study were perfectly symmetric after the blepharoptosis operation, with 70% asymmetric. These 70% showed good symmetry immediately after surgery, but asymmetry occurred 6 months after the operation. Conclusion In blepharoptosis surgery, different techniques for double eyelids must be applied according to the method of ptosis correction used. Usually, the height of the double eyelid on the ptotic side should be a little less than the normal double eyelid height on the nonptotic side. However, it is difficult to achieve symmetric double eyelids in blepharoptosis patients.     

部分睑板全层切除联合提上睑肌缩短术矫正中重度上睑下垂

目的:探讨部分睑板全层切除联合提上睑肌缩短术矫正中重度上睑下垂的方法和疗效。方法:对15例(2007年～2011年)(19只眼)中重度上睑下垂患者行部分睑板全层切除联合提上睑肌缩短术。结果:术后随访6个月～3年,本组15例(19只眼)中重度上睑下垂均矫正满意(外观满意,弧度自然)。早期均有不同程度的眼睑闭合不全的情况,一般术后1～3个月内完全恢复,无并发症发生。结论:部分睑板全层切除联合提上睑肌缩短术,此手术操作简单,并发症少,而且疗效确切。     

Restoration of involuntary tonic contraction of the levator muscle in patients with aponeurotic blepharoptosis or Horner syndrome by aponeurotic advancement using the orbital septum.

Müller's muscle can be thought of as a large serial type of muscle spindle of the levator muscle. Effective stretching of the mechanoreceptor in the proximal part of Müller's muscle by voluntary phasic contraction of the levator muscle for initial opening of the eye induces involuntary tonic contraction of the levator muscle as a stretch reflex via the mesencephalic trigeminal nucleus, to maintain an adequate visual field. After disinsertion of the levator aponeurosis from the tarsus by habitual rubbing, elongation of Müller's muscle secondary to thinning (aponeurotic blepharoptosis) or paralysis (Horner syndrome) desensitises the mechanoreceptor of Müller's muscle, resulting in blepharoptosis. Shortening of the elongated and thinned Müller's muscle by instillation of phenylephrine, and surgical shortening, and fixation of the disinserted, elongated, and thinned aponeurosis using the orbital septum, restored involuntary tonic contraction of the levator muscle in nearly all of 2000 patients with aponeurotic blepharoptosis and in 11 patients with Horner syndrome.     

RESTORATION OF INVOLUNTARY TONIC CONTRACTION OF THE LEVATOR MUSCLE IN PATIENTS WITH APONEUROTIC BLEPHAROPTOSIS OR HORNER SYNDROME BY APONEUROTIC ADVANCEMENT USING THE ORBITAL SEPTUM

Müller's muscle can be thought of as a large serial type of muscle spindle of the levator muscle. Effective stretching of the mechanoreceptor in the proximal part of Müller's muscle by voluntary phasic contraction of the levator muscle for initial opening of the eye induces involuntary tonic contraction of the levator muscle as a stretch reflex via the mesencephalic trigeminal nucleus, to maintain an adequate visual field. After disinsertion of the levator aponeurosis from the tarsus by habitual rubbing, elongation of Müller's muscle secondary to thinning (aponeurotic blepharoptosis) or paralysis (Horner syndrome) desensitises the mechanoreceptor of Müller's muscle, resulting in blepharoptosis. Shortening of the elongated and thinned Müller's muscle by instillation of phenylephrine, and surgical shortening, and fixation of the disinserted, elongated, and thinned aponeurosis using the orbital septum, restored involuntary tonic contraction of the levator muscle in nearly all of 2000 patients with aponeurotic blepharoptosis and in 11 patients with Horner syndrome.     

先天性无眼球症的整形治疗

目的 探讨先天性无眼球症的整形治疗方法。方法 手术分二期进行，一期行骨性眶窝扩大的全眼窝再造术与耳软骨移植睑板再造术，二期行上睑提肌缩短或额肌瓣悬吊的上睑下垂矫正术。结果 5例手术均获成功，效果满意。结论 骨性眶窝扩大与睑板再造后上睑下垂矫正可获得较好的义眼植入与睁眼效果。     

提上睑肌缩短联合睑板部分切除术在中重度上睑下垂患者中的应用效果

目的 探讨对中重度上睑下垂患者实施提上睑肌缩短联合睑板部分切除术的临床效果。方法 选择2019年11月-2022年11月我院收治的90例中重度上睑下垂患者为研究对象，采用随机数字表法分为 对照组和研究组，各45例。对照组行额肌瓣悬吊术，研究组行提上睑肌缩短联合睑板部分切除术，比较 两组临床疗效、眼表指标[泪液分泌试验（SIt）、泪膜破裂时间（BUT）、角膜荧光素染色（FL）]、并 发症发生情况及矫正满意度。结果 研究组治疗总有效率为97.78%，高于对照组的82.22%（P ＜0.05）； 研究组术后1个月BUT短于对照组（P ＜0.05）；两组SIt、FL比较，差异无统计学意义（P ＞0.05）；研 究组并发症发生率为6.67%，低于对照组的22.22%（P ＜0.05）；研究组矫正满意度为95.56%，高于对照 组的80.00%（P＜0.05）。结论 提上睑肌缩短联合睑板部分切除术在中重度上睑下垂患者中的应用效果确 切，可有效缓解患者上睑下垂情况，改善眼表指标，且术后并发症较少，安全性较高，有利于提升矫正满 意度，值得临床应用。     

眶隔筋膜瓣与额肌瓣重叠吻合悬吊矫正重度上睑下垂

目的:为更好地保持眼睑的原有结构,符合其生理和生物力学特点,探索一种治疗重度上睑下垂的新方法。方法:术中于眼轮匝肌下分离并显露眶隔筋膜至近眶上缘处,在眶隔表面设计一蒂位于睑板上缘的梯形瓣,按设计线全层切开眶隔,形成眶隔筋膜瓣。在患侧眉上形成一额肌瓣,将两瓣相互重叠缝合固定,上提睑缘至角膜上缘处,起到悬吊上睑、矫正下垂畸形的作用。结果:作者利用该方法对22例26侧重度上睑下垂的眼睑进行了治疗,随访病人17例,19侧眼睑,其中16侧眼睑取得了满意的效果,额肌收缩时患睑睁大两侧眼裂大小对称,可达到正常睑缘的位置。睑缘弧度及重睑外形满意。3侧眼睑矫正不完全,经二次手术修复得以矫正。讨论:作者认为利用眶隔筋膜形成的组织瓣与额肌瓣重叠吻合悬吊缝合,保持了眼睑的原有结构,具有手术损伤轻,上睑悬吊牢固,不易复发,睑缘和重睑线弧度及外观满意,畸形矫正效果良好,优于传统的单纯额肌悬吊术和上睑提肌腱膜瓣悬吊的方法。     

改良的额肌瓣辅以缝线悬吊减张治疗上睑下垂

目的　为了减少额肌损伤 ,保证额肌瓣转移 ,治疗中、重度上睑下垂 ,术后吻合口无张力愈合 ,加快血运建立的效果。方法　用 3 - 0可吸收缝线横向贯穿睑板上缘提上睑肌腱膜组织 2针 ,经额肌瓣隧道缝至眶上缘骨膜上 ,转移不等边额肌瓣使之无张力缝合。结果　减张手术组 2 5例 ,总优良率 92 % ,常规手术组 34例 ,总优良率 61 .1 8%。结论　本手术方法减少了额肌瓣外侧血管神经损伤 ,增强了额肌的收缩力 ,利用缝线悬吊减张辅助吻合口愈合 ,是治疗中、重度上睑下垂的有效辅助方法     

Correction of myopathic blepharoptosis by check ligament suspension: clinical evaluation of 89 eyelids

Myopathic blepharoptosis is a congenital anomaly of the eyelid. The levator muscle does not function because of primary myogenic atrophy. Different procedures based on eyelid suspension, or the simple or combined resection of the eyelid have been described. A simple dynamic suspension of the tarsus to the check ligament of the superior fornix, neither sacrificing nor adding any tissue was used for 89 procedures on 71 consecutive patients with primary myopathic blepharoptosis. Their mean age at operation was 16 years (range 2-58) and the follow up ranged from 2 months to 12 years. Ptosis was unilateral in 53 patients (33 left, 20 right) and bilateral in 18. Preoperatively 27 had mild ptosis (1-2 mm), 33 moderate (3-4 mm), and 29 severe (>4 mm). The patients were divided into two groups: not previously operated on (50 patients/63 eyelids) and previously operated on by other techniques (21 patients/26 eyelids); both groups were compared for duration of procedure, normalisation rate, and number of revisions. In the unoperated group the normalisation rate was 81% (51 eyelids), and to achieve a good final result nine eyelids were revised once, while just three were reoperated on twice (19%). In the group previously operated on the normalisation rate was 69% (18 eyelids), while 3 eyelids needed one revision (12%). In unilateral cases the normalisation rate was 79% (42 eyelids) and in bilateral 75% (27 eyelids). In unilateral blepharoptosis there were 13% of revisions (7 eyelids) while bilaterally there were 22% (8 eyelids). Despite a previous operation, the operating time of a unilateral correction was similar in both groups, while the number of revisions needed to achieve the final result was low for unilateral ptosis, but higher for bilateral ones. This simple atraumatic suspension technique produced an improvement in all cases and it seemed useful in both primary and secondary cases.     

额肌瓣悬吊术治疗重度上睑下垂临床探索

目的:探索重度上睑下垂的治疗方法.方法:制作宽窄和长度适宜的额肌瓣,经眼轮匝肌与眶隔膜间隧道,下移固定于睑板上缘,治疗重度上睑下垂97例.结果:临床治疗126只眼(97例),随访0.5～9年,外形自然,闭合自如,无复发现象,均获满意效果.结论:额肌瓣悬吊术是活疗重度上睑下垂可靠而有效的方法.     

Management of the blepharoplasty patient with ptosis

Patients who request correction of both dermatochalasis and acquired blepharoptosis require separate evaluation of each condition. The blepharoplasty is done in the standard way, depending on the amount of skin redundancy and fat herniation. The method of ptosis repair is dependent on whether Müller's muscle or levator aponeurosis is weak, the degree of ptosis and levator function, and the position of the upper eyelid crease. A tarsal Müller's muscle resection is employed in cases where the ptosis is minimal, the upper eyelid crease is normal, or the phenylephrine test is positive. A levator advancement is done if the ptosis is due to a levator aponeurosis dehiscence or attenuation with a higher than normal upper eyelid crease and thinning of the eyelid. Both procedures are easily combined with an upper eyelid blepharoplasty.