反复发作抑郁症1例

患者,女,41岁,已婚,反复出现情绪低落,反应迟钝,不能劳动10年。于1996年5月入院。　　1987年4月,患者无原因出现话少,没兴趣,无精力,反应慢,不能劳动,整日卧床,需督促及协助料理日常生活,每次发病时,心里沉重,忧虑、发愁,脑子不会思考,想着该做饭了,却不知道怎么动手做,身边人说话声音好象从很远处传来,周围的事物象假的,如在梦里,睡眠多,食量大。自觉活着没意思,想死。病情持续至同年9月,患者在1周内迅速恢复正常。从此,每年的同期(4月～9月),患者都处于上述状态中,每次的起病形式,病程,症状,病情进展与恢复过程均相似。曾被诊断为癔病,脑…     

发作性左侧肢体无力 言语含糊

病历摘要患者女性,54岁。主因发作性左侧肢体无力、言语含糊10 h,于2010年7月14日入院治疗。患者于发病当日凌晨3:30突发左侧肢体无力、言语含糊,无眩晕、恶心、呕吐、心悸,无意识障碍,症状持续约10 min后完全缓解,至清晨4时再次发作2次,每次3～10 min。至外院就诊时再次发作,性质基本同前,持续约3 min自行缓解。发作时体格检查:血压170/100 mm Hg(1 mm Hg=0.133 kPa),心率70次/min,心律齐。神志清楚,言语含糊,伸舌左偏;左侧肢体肌力3级,病     

发作性左侧肢体无力言语含糊

病历摘要患者女性,54岁。主因发作性左侧肢体无力、言语含糊10h,于2010年7月14日入院治疗。患者于发病当日凌晨3：30突发左侧肢体无力、言语含糊,无眩晕、恶心、呕吐、心悸,无意识障碍,症状持续约10min后完全缓解,至清晨4时再次发作2次,每次3～10min。至外院就诊时再次发作,     

恶性综合征反复发作1例

<正>1 病例患者男,50岁,因兴奋与情绪低交替34年,再发情绪低半个月于2018年1月3日拟诊断双相情感障碍,目前为伴有精神症状的抑郁发作入住我院。既往有3次恶性综合征(NMS)病史,前两次发作时患者根据病情变化增减药物,当地医院诊断为NMS后随医嘱不再增减药物。第3次发病在本院住院治疗期间,诊断NMS后停用抗精神病药,予补液支持及无抽搐电休克(MECT)治疗。此次入院查体未见明显阳性体征。精神检查:意识清,情绪低落,接触被动,表情     

反复脑梗死的POEMS综合征1例及文献复习

POEMS综合征是一种与浆细胞异常增生有关的多系统损害疾病,临床上合并脑梗死极少见,而以反复脑梗死为突出表现的POEMS综合征仅Tracey Garcia等[1]在2007年报道了2例,国内尚未见。本文通过报道1例因反复脑梗死2次入住我科治疗的的POEMS综合征病例,复习相关文献,对其临床表现、血液有形成分、电生理、影像学及可能的病理生理机制进行分析,探讨POEMS综合征与脑梗死之间的内     

双相障碍抑郁发作反复“间接自杀”1例报告

正双相障碍患者抑郁发作时可出现自杀观念及行为[1]。患者的自杀行为以"直接自杀"多见,"间接自杀"较少报道。间接自杀是患者抑郁发作时,因情绪极度低落,企图自杀,但又恐惧自我伤害或既往自杀失败,故采取杀害他人的方式,使自己被司法机关判处死刑,从而达到自杀目的。本文报告1例双相障碍抑郁发作反复出现"间接自杀"案例及其司法鉴定意见,以期为司法精神鉴定实践及此类患者的治疗和监管提供一些参考信息。     

左侧肢体无力、言语不利

病历摘要 患者男性,70岁.因左侧肢体无力、言语不利4个月,于2009年5月6日入院治疗.患者于发病前4个月突发左侧肢体无力、言语含混不清,无眩晕、恶心、呕吐、黑蒙、肢体麻木.     

左侧肢体无力、言语不利

患者男性,70岁。因左侧肢体无力、言语不利4个月,于2009年5月6日入院治疗。患者于发病前4个月突发左侧肢体无力、言语含混不清,无眩晕、恶心、呕吐、黑蒙、肢体麻木。发病后6h于外院行头部CT检查显示,右侧半卵网中心斑片状低密度影,边界欠清晰;MRI扫描可见右侧颞叶、基底节区及放射冠区大面积脑梗死（图1,2）。     

反复发作性右下肢无力1例

患者男性,39岁,已婚。89年2月10日工作时突然发生右下肢麻木无力,未行任何治疗,数分钟后恢复正常。3月1日骑自行车时又突然右下肢麻木无力,倒地,当时右下肢完全不能活动,经按摩针炙,半小时后恢复正常。相隔半小时又类似发作一次,持续半小时后再度恢复正常,逐来院就诊。大小便一直正常。无腰痛。     

午后烤炉综合征反复发作1例

1　资　　料患者 ,女性 ,5 1岁 ,诊断偏执型分裂症。病期 15年 ,住院至今已 14年。现服用甲硫哒嗪 2 5 0mg/d治疗。患者目前表现被动、孤僻退缩 ,无幻觉妄想。近几年常有过多饮水 ,伴呕吐清水、多尿现象。 2 0 0 3年 5月 19日下午 3时 ,患者呕吐清水约 80 0mL ,当时意识模糊 ,约 15分钟后进入浅昏迷状态。测体温 35 6℃ ,血压 12 0 / 80mmHg ,瞳孔等圆等大约5mm ,口角抽动 ,双手细微震颤 ,肌张力正常 ,未引出病理反射。血生化结果 :K+ 4 0 1mmol/L ;Na+ 117 4mmol/L ;CI-89 3mmol/L ;Bs5 4 2mmol/L ;BUN4 74mmol/L ;Cr115 7mmol…     

Physical Activity Patterns in Youth with Autism Spectrum Disorders

The purpose of this study was to examine age-related physical activity patterns in youth with autism spectrum disorders (ASD). Thirty youth, aged 10–19 years, were divided into three groups: elementary (n=9), middle (n=9) and high (n=12) school. Participants wore an accelerometer and completed an activity questionnaire for seven consecutive days. The main findings were that (a) elementary youth are more active than the other groups, regardless type of day or time period, and (b) there are no consistent patterns in physical activity of youth with ASD according to day or time period. Findings emphasize that interventions for this population should address increasing extracurricular physical activity options during adolescence.     

卒中后神经精神障碍一例

1 病例简介 　　1.1 病史 患者男,56岁,大学文化,机关干部.患者2007年5月突然出现记忆力丧失、言语不利,无明显肢体活动障碍.头颅CT示;左侧半球脑梗死,累及颞、枕、顶及大脑中动脉供血区(图1).具体治疗不详,1个月余病情好转,家人发现其与人交谈时有停顿及找词困难.2007年9月3日,患者因悲伤,在情绪激动后再次出现不认识家人,烦躁不安,无法与人交流,记忆力下降并有头痛,无呕吐、意识不清及肢体活动障碍.急诊头颅CT示:左颞、顶、枕叶陈旧脑梗死(图2).……     

The Effect of Physical Activity Interventions on Executive Function Among People with Neurodevelopmental Disorders: A Meta-Analysis

Journal of Autism and Developmental Disorders - The current meta-analysis comprehensively examined the effects of physical activity interventions on executive function among people with...     

Maternal Recurrent Mood Disorders and High-Functioning Autism

A quantitative examination was made of the association of parental mood and anxiety disorders with severity of disability within a large sample of young children with Pervasive Developmental Disorder (PDD). Maternal recurrent mood disorders were associated with elevated cognitive and adaptive functioning in their affected children, parent reports of increased behavior problems and teacher reports of an internalizing behavioral style. Maternal histories of anxiety disorders and paternal depression or anxiety disorders were not associated with levels of adaptive/cognitive functioning or levels of maladaptive behaviors in the children. Various genetic models are discussed. It is hypothesized that genes associated with recurrent depression in women may exert a "protective" effect on cognition and adaptive functioning in children with PDD.     

视神经脊髓炎谱系疾病1例报道并文献复习

目的提高对视神经脊髓炎谱系疾病(NMOSD)的认识。方法报道1例以脑干症状为首发、继以急性横贯性脊髓炎的NMOSD患者,结合文献复习进行分析。结果青年女性患者,发病时表现为左侧味觉减退以及左侧面部瘙痒,继以出现急性横贯性脊髓炎。MRI显示延髓右侧和左侧桥脑被盖部、中脑导水管周围长T1、长T2信号病灶,脊髓MRI显示颈1~5长T2信号病灶;血清水通道蛋白4(AQP4)抗体阳性。患者符合AQP4抗体阳性NMOSD的诊断标准。结论 NMOSD常有脑部症状,尤其是脑干症状。部分患者可以脑干症状为首发临床表现,对此类患者应及早行AQP4抗体检测,以明确诊断及早干预。     

Exploring the Relationship Between Movement Disorders and Physical Activity in Patients With Schizophrenia: An Actigraphy Study

Low physical activity (PA) and sedentary behavior (SB) are major contributors to mental health burden and increased somatic comorbidity and mortality in people with schizophrenia and related psychoses. Movement disorders are highly prevalent in schizophrenia populations and are related to impaired functioning and poor clinical outcome. However, the relationship between movement disorders and PA and SB has remained largely unexplored. Therefore, we aimed to examine the relationship between movement disorders (akathisia, dyskinesia, dystonia, and parkinsonism) and PA and SB in 216 patients with schizophrenia and related psychoses. Actigraphy, the St. Hans Rating Scale for extrapyramidal syndromes, and psychopathological ratings (PANSS-r) were applied. Data were analyzed using multiple linear regression, adjusting for sex, age, negative symptoms, and defined daily dose of prescribed antipsychotics. Parkinsonism was significantly associated with decreased PA (β = −0.21, P < .01) and increased SB (β = 0.26, P < .001). For dystonia, only the relationship with SB was significant (β = 0.15, P < .05). Akathisia was associated with more PA (β = 0.14, P < .05) and less SB (β = −0.15, P < .05). For dyskinesia, the relationships were non-significant. In a prediction model, akathisia, dystonia, parkinsonism and age significantly predicted PA (F(5,209) = 16.6, P < .001, R²_Adjusted = 0.27) and SB (F(4,210) = 13.4, P < .001, R²_Adjusted = 0.19). These findings suggest that movement disorders, in particular parkinsonism, are associated with reduced PA and increased SB in patients with psychotic disorders. Future studies should take movement disorders into account when examining PA and SB, to establish the clinical value of movement disorders in activating people with psychotic disorders to improve their mental and somatic health.     

Hemispheric Timesharing: Verbal and Spatial Loading with Concurrent Unimanual Activity

Thirty right-handed university students (15 male and 15 female) engaged in a unimanual task involving sequential finger movement alone and in four conditions with concurrent cognitive activity. Overall the two “spatial” tasks interfered with activity of the left hand more than the right and the two “verbal” tasks interfered more with right than left hand activity. These findings were interpreted as support for a hemispheric timesharing model which proposes that two concurrently performed tasks interfere with each other to the extent that they compete for the same cerebral space.