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1.
Thesis·AcuteEffectsofChineseHerbsonthePeritonealDialysisEfficacyandPeritonealUltrastuctureXiChunsheng ,etal.1:( 1)…………………EffectsofHaslPlusChemotherapyonPeripheralBloodTCellSubsetsandNKCellActivityinPatientswithOvarianEpithelialCarcinomaZhuGenhai,etal.1:( 3)……  相似文献   

2.
Role of p38 protein kinase in heat-induced Raw cells apoptosis   总被引:5,自引:1,他引:4  
Aftercellsareexposedtoastressingagent,celldeathcanbeobservedasapoptosis,necrosisandmitoticdeathApoptosisorphysiologiccelldeath,isundergeneticcontrolandischaracterizedmorphologicallybycellshrinkage,marginationofchromatinandnuclearfragmentationGenomicDNA…  相似文献   

3.
Effective chemotherapy induce apoptosis in vivo in patients with leukemia   总被引:2,自引:0,他引:2  
Somestudiesinvitrosuggestthatapoptosisisthemodeofcelldeathinleukemiacells ,1 3  Chemotherapydrugskillleukemiacellsthroughinductionofapoptosis 4 ,5 Blockingtheapoptosissignalingcouldbeanothermechanismformulti drugresistance 6 Howeverlittleisknownaboutapoptos…  相似文献   

4.
Hydroxyapatiteultrofinepowder(HAUFP)cangetintotumorcellularnucleiandcombinewithDNAtokillandinhibittumorcells[1].Butfewreportswereavail-ableonitsdamagingeffectontumorcellsandnormalcells.Singlecellgelelec-trophoresis(SCGE)isafastandsensitivetechniquewh…  相似文献   

5.
Neuralstemcellsisagroupofundifferentiated ,multipotentcellswiththecapacityofself -renewalanddifferentiatingintoneurons ,astrocytesandoligo dendrocytes .Theycanbeactivatedaftercentralner vousinjurytoparticipatetheregeneration[1~ 4 ] .Itisconsideredthatneuralst…  相似文献   

6.
Mesenchymalstemcells (MSCs)aremulti potentialcells ,locatedinperiosteum ,bonetra becula,skeletalmuscleanddermis,whichhavetheabilitytodifferentiateintoseveraltypesofcell,suchasosteocyte ,chondrocyte ,cardiacmy ocyteandneuron[1,2 ] .SeperationofMSCsisrela tivelycon…  相似文献   

7.
Nephroticsyndrome (NS)isarenaldiseasecharacterizedmainlybyproteinuriaandhypoal buminemia.Theprecisepathogenesisofthissyndromeisunclear.Ithasbeensuggestedthatthedisturbanceofcellularimmunityplaysama jorroleinthemechanismsofNS .IL 1 3,pro ducedbyTh2cells ,canun…  相似文献   

8.
Fas (CD95)andFasligand (FasL) ,asmembersofTNFfamilies ,aretypeⅠandtypeⅡcellulartransmembraneproteins FasLinducesapoptosisbybindingtoitsreceptorFasonthecellsurface Thisprocessisinvolvedinimmuneresponsetovirus ,tumorcellsandtheregulationoflymphocytehomeostasis…  相似文献   

9.
Liverfibrosisisanabnormalproliferationpathologicpro cessofintrahepaticfibrousconnectivetissuethatoccursafterlivercellshavebeenne  相似文献   

10.
Vascularendothelialgrowthfactor(VEGF)isaheparinbinding,secretedgrowthfactorthatisangiogenicinvivo,andhasauniquetargetcellspecificityforvascularendothelialcellsSomestudiesshowedthatexpressionofVEGFissignificantlyincreasedbyhypoxiainadulttissueandmyo…  相似文献   

11.
Transfection and expression of HCV-NS5B gene in Huh-7 cells   总被引:1,自引:0,他引:1  
Methods NS5BgenehasbeentransfectedintoHuh 7cellsbylipofectamine TheresultsoftransfectionwereconfirmedbyPCRandSouthernblotanalysis ,andthelevelofthenon structuralprotein 5B(NS5B)inHuh 7cellswasdetectedbyWesternblotanalysis Results TherewereNS5Bgenefragmentsan…  相似文献   

12.
INTRODUCTION  CD9antigen(Ag)isa 2 4 kDmembraneglycoproteinexpressedonthesurfaceofhumanplateletsaswellasonthesurfaceoflymphoidprogenitorcells ,pre Bcellleukemiaandothercelltypes.Thisproteinbelongstoarecentlydelin eatedfamilyofcell surfaceAgsthatspanthemembra…  相似文献   

13.
Differentiationtherapyisanattractivealter nativeincaseswherecytotoxictherapyisnotef fective .Theunderlyinghypothesisisthatneo plastictransformationresultsfromdefectsincel lulardifferentiation ;inducingtumorcellstodif ferentiatewouldresultinreversalofitsm…  相似文献   

14.
The role of c-myc in regulating mdr1 gene expression in tumor cell line KB   总被引:5,自引:0,他引:5  
Thec mycproto oncogeneplaysaroleinmanycellularprocesses ,suchasproliferation ,differentiationandapoptosis Itisanearly responsegenenecessaryforcell cycleprogression (G1 Stransition)andactivatesquiescentcellsintothecellcycle (G0 G1transition) Down regulationofc …  相似文献   

15.
Humanherpesvirus 7(HHV 7)isoneofthemostrecentlydiscoveredmemberoftheher pesvirusfamily .Itwasfirstisolatedfromactivat edCD4 Tcellsfromperipheralbloodmononu clearcells (PBMCs)ofahealthyindividual[1] ,apatientwithchronicfatiguesyndrome(CFS) [2 ] ,andfromsalivaofheal…  相似文献   

16.
Paraoxysmalnocturnalhemoglobinuria(PNH),anacquireddiseaseofhematopoieticstemcell,isoneofthecommonesthemolyticdisordersinthenorthernprovincesofChina.Despitetheimportantbreakthroughsinelucidatingitsetiologyandpathogenesismadeinrecentyears,littleprogre…  相似文献   

17.
MolecularbasisoftheadhesiveprocessofpolymorphonuclearneutrophilstovascularendothelialcellsunderendotoxinconditionZhouXiangdon...  相似文献   

18.
Intracerebralhemorrhagefrequentlyoccursinner voussystemdiseases ,andleadstosecondarycerebralle sion ,suchasischemia ,edemaofperihematomalbrainre gionsandthebiochemicalchangeofthecell.Recentstudieshaveconfirmedthatcytokinessuchasbasicfi broblastgrowthfacto…  相似文献   

19.
CelladhesionmoleculesmaymediatethechemotacticmigrationbetweencellsorcellsandinterstitiumRecentstudies1,2havefoundthatdialysiswithcellulosemembranescouldleadtochangesintheexpressionofleukocyteadhesionmolecules,suchasCD11bandLselectin,ongranulocytesandmon…  相似文献   

20.
Apoptosisisaprocessofcell”suicide”inwhichthecellactivelykillsitselfataphysiologi calorpathologicalconditionoccurringininjuredspinalcord .Toexploretheprotectivemechanismsofnervegrowthfactor(NGF)oninjuredspinalcord ,thechangesofthebcl 2proteinweremea suredb…  相似文献   

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